CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = E93D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp193E93DE93DnonsyngaAgaC8016330.790262542-544
ORF1ab/nsp193E93DE93DnonsyngaAgaT8011680.209738542-544

Details of the mutation E93D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp193E93DgaAgaC633801All0.000121
ORF1ab/nsp193E93DgaAgaT168801All0.000032
ORF1ab/nsp193E93DgaAgaC493493B.1.4290.0116
ORF1ab/nsp193E93DgaAgaT89120B.1.1.70.00008
ORF1ab/nsp193E93DgaAgaC31120B.1.1.70.000028
ORF1ab/nsp193E93DgaAgaT4056AY.4.20.000868
ORF1ab/nsp193E93DgaAgaC1656AY.4.20.000347
ORF1ab/nsp193E93DgaAgaC1820AY.40.000028
ORF1ab/nsp193E93DgaAgaT220AY.40.000003
ORF1ab/nsp193E93DgaAgaC1818AY.1030.000112
ORF1ab/nsp193E93DgaAgaC99B.1.5250.001018
ORF1ab/nsp193E93DgaAgaC47B.10.000037
ORF1ab/nsp193E93DgaAgaT37B.10.000027
ORF1ab/nsp193E93DgaAgaC46AY.440.000024
ORF1ab/nsp193E93DgaAgaT26AY.440.000012
ORF1ab/nsp193E93DgaAgaC55AY.290.000079
ORF1ab/nsp193E93DgaAgaT35AY.430.000013
ORF1ab/nsp193E93DgaAgaC25AY.430.000009
ORF1ab/nsp193E93DgaAgaC44AY.4.50.00043
ORF1ab/nsp193E93DgaAgaT34B.1.10.000054
ORF1ab/nsp193E93DgaAgaC14B.1.10.000018
ORF1ab/nsp193E93DgaAgaT44B.1.1.3180.001207
ORF1ab/nsp193E93DgaAgaC44B.1.1.5190.000159
ORF1ab/nsp193E93DgaAgaT34B.1.617.20.000011
ORF1ab/nsp193E93DgaAgaC14B.1.617.20.000004
ORF1ab/nsp193E93DgaAgaC33B.1.1.2200.005576
ORF1ab/nsp193E93DgaAgaC23B.1.4270.000101
ORF1ab/nsp193E93DgaAgaT13B.1.4270.00005
ORF1ab/nsp193E93DgaAgaC22AY.1200.000074
ORF1ab/nsp193E93DgaAgaT22AY.250.000012
ORF1ab/nsp193E93DgaAgaC22AY.30.00002
ORF1ab/nsp193E93DgaAgaC12AY.98.10.000048
ORF1ab/nsp193E93DgaAgaT12AY.98.10.000048
ORF1ab/nsp193E93DgaAgaT22B.1.1.5230.003125
ORF1ab/nsp193E93DgaAgaT22B.1.1770.000026
ORF1ab/nsp193E93DgaAgaT22B.1.20.000018
ORF1ab/nsp193E93DgaAgaC11A.20.000662
ORF1ab/nsp193E93DgaAgaT11AY.1000.000046
ORF1ab/nsp193E93DgaAgaT11AY.160.00038
ORF1ab/nsp193E93DgaAgaC11AY.3.10.000085
ORF1ab/nsp193E93DgaAgaC11AY.420.00004
ORF1ab/nsp193E93DgaAgaT11AY.610.000105
ORF1ab/nsp193E93DgaAgaT11AY.75.10.00018
ORF1ab/nsp193E93DgaAgaT11AY.840.000437
ORF1ab/nsp193E93DgaAgaC11AY.99.20.000092
ORF1ab/nsp193E93DgaAgaC11B.1.2210.000071
ORF1ab/nsp193E93DgaAgaT11B.1.2580.000067
ORF1ab/nsp193E93DgaAgaC11B.1.258.170.000104
ORF1ab/nsp193E93DgaAgaC11B.1.3110.000275
ORF1ab/nsp193E93DgaAgaT11B.1.4000.000429
ORF1ab/nsp193E93DgaAgaC11B.1.4590.004082
ORF1ab/nsp193E93DgaAgaT11B.1.466.20.000391
ORF1ab/nsp193E93DgaAgaC11B.1.6210.000089
ORF1ab/nsp193E93DgaAgaC11B.1.621.10.000506
ORF1ab/nsp193E93DgaAgaC11B.1.6360.006711
ORF1ab/nsp193E93DgaAgaC11B.1.90.006173
ORF1ab/nsp193E93DgaAgaT11B.330.021277
ORF1ab/nsp193E93DgaAgaC11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.