CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = D147V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1147D147VD147VnonsyngAcgTc80380.475704-706
ORF1ab/nsp1147D147VD147VnonsyngACgTG80190.2375704-706
ORF1ab/nsp1147D147VD147VnonsyngACgTA80130.1625704-706
ORF1ab/nsp1147D147VD147VnonsyngACgTT80100.125704-706

Details of the mutation D147V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1147D147VgAcgTc3880All0.000007
ORF1ab/nsp1147D147VgACgTG1980All0.000004
ORF1ab/nsp1147D147VgACgTA1380All0.000002
ORF1ab/nsp1147D147VgACgTT1080All0.000002
ORF1ab/nsp1147D147VgAcgTc1029B.10.000092
ORF1ab/nsp1147D147VgACgTA829B.10.000073
ORF1ab/nsp1147D147VgACgTT629B.10.000055
ORF1ab/nsp1147D147VgACgTG529B.10.000046
ORF1ab/nsp1147D147VgAcgTc1328B.1.1.70.000012
ORF1ab/nsp1147D147VgACgTG1128B.1.1.70.00001
ORF1ab/nsp1147D147VgACgTA228B.1.1.70.000002
ORF1ab/nsp1147D147VgACgTT228B.1.1.70.000002
ORF1ab/nsp1147D147VgAcgTc45B.1.617.20.000015
ORF1ab/nsp1147D147VgACgTT15B.1.617.20.000004
ORF1ab/nsp1147D147VgACgTG13B.1.1.10.000327
ORF1ab/nsp1147D147VgAcgTc13B.1.1.10.000327
ORF1ab/nsp1147D147VgACgTA13B.1.1.10.000327
ORF1ab/nsp1147D147VgACgTA13B.1.1770.000013
ORF1ab/nsp1147D147VgAcgTc13B.1.1770.000013
ORF1ab/nsp1147D147VgACgTG13B.1.1770.000013
ORF1ab/nsp1147D147VgACgTG13B.1.2580.000067
ORF1ab/nsp1147D147VgAcgTc13B.1.2580.000067
ORF1ab/nsp1147D147VgACgTA13B.1.2580.000067
ORF1ab/nsp1147D147VgAcgTc22AY.1020.000053
ORF1ab/nsp1147D147VgAcgTc22AY.40.000003
ORF1ab/nsp1147D147VgAcgTc11AY.390.000025
ORF1ab/nsp1147D147VgAcgTc11B.1.177.210.000076
ORF1ab/nsp1147D147VgACgTT11B.1.177.70.000165
ORF1ab/nsp1147D147VgAcgTc11B.1.5050.004386
ORF1ab/nsp1147D147VgAcgTc11B.1.5260.000024

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.