CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : CodonNum = 114 & Codon = aCa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1114I114TI114TnonsynaTaaCa307230721605-607

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1114I114TaTaaCa30723072All0.000588
ORF1ab/nsp1114I114TaTaaCa952952B.1.1.70.000852
ORF1ab/nsp1114I114TaTaaCa451451B.1.1110.529965
ORF1ab/nsp1114I114TaTaaCa271271AY.40.000422
ORF1ab/nsp1114I114TaTaaCa204204B.1.5250.023085
ORF1ab/nsp1114I114TaTaaCa128128AY.250.00077
ORF1ab/nsp1114I114TaTaaCa125125B.1.2580.008318
ORF1ab/nsp1114I114TaTaaCa9191B.1.617.20.000343
ORF1ab/nsp1114I114TaTaaCa6969B.1.20.000608
ORF1ab/nsp1114I114TaTaaCa6565B.1.4290.001529
ORF1ab/nsp1114I114TaTaaCa4949B.10.000449
ORF1ab/nsp1114I114TaTaaCa3939AY.1030.000242
ORF1ab/nsp1114I114TaTaaCa3939AY.430.000173
ORF1ab/nsp1114I114TaTaaCa3636AY.800.040632
ORF1ab/nsp1114I114TaTaaCa3535AY.440.000213
ORF1ab/nsp1114I114TaTaaCa2727B.1.1.5190.001072
ORF1ab/nsp1114I114TaTaaCa2222B.1.2430.001531
ORF1ab/nsp1114I114TaTaaCa2121P.10.000331
ORF1ab/nsp1114I114TaTaaCa2020B.1.10.000363
ORF1ab/nsp1114I114TaTaaCa1818B.1.5750.005461
ORF1ab/nsp1114I114TaTaaCa1414AY.990.01469
ORF1ab/nsp1114I114TaTaaCa1414B.4.70.141414
ORF1ab/nsp1114I114TaTaaCa1212AY.580.010889
ORF1ab/nsp1114I114TaTaaCa1111AY.30.000109
ORF1ab/nsp1114I114TaTaaCa1010AY.1100.001127
ORF1ab/nsp1114I114TaTaaCa1010AY.1190.000353
ORF1ab/nsp1114I114TaTaaCa1010AY.390.000247
ORF1ab/nsp1114I114TaTaaCa99AY.860.007469
ORF1ab/nsp1114I114TaTaaCa99B.1.3510.000268
ORF1ab/nsp1114I114TaTaaCa99B.1.5960.000784
ORF1ab/nsp1114I114TaTaaCa88AY.200.000311
ORF1ab/nsp1114I114TaTaaCa88AY.260.000226
ORF1ab/nsp1114I114TaTaaCa88Q.10.001011
ORF1ab/nsp1114I114TaTaaCa77AH.11
ORF1ab/nsp1114I114TaTaaCa77AY.1000.000322
ORF1ab/nsp1114I114TaTaaCa77B.1.438.40.148936
ORF1ab/nsp1114I114TaTaaCa77P.1.140.000335
ORF1ab/nsp1114I114TaTaaCa66AY.1020.000159
ORF1ab/nsp1114I114TaTaaCa66AY.4.20.00013
ORF1ab/nsp1114I114TaTaaCa66AY.4.50.000645
ORF1ab/nsp1114I114TaTaaCa66B.1.177.200.009105
ORF1ab/nsp1114I114TaTaaCa66B.1.177.210.000459
ORF1ab/nsp1114I114TaTaaCa66B.1.6280.002114
ORF1ab/nsp1114I114TaTaaCa55AY.1180.000313
ORF1ab/nsp1114I114TaTaaCa55AY.4.40.002046
ORF1ab/nsp1114I114TaTaaCa55AY.9.20.000184
ORF1ab/nsp1114I114TaTaaCa55AY.99.20.000461
ORF1ab/nsp1114I114TaTaaCa55B.1.5260.000118
ORF1ab/nsp1114I114TaTaaCa55B.1.6210.000443
ORF1ab/nsp1114I114TaTaaCa55B.1.6370.000365
ORF1ab/nsp1114I114TaTaaCa55P.1.150.001162
ORF1ab/nsp1114I114TaTaaCa44AY.1070.001864
ORF1ab/nsp1114I114TaTaaCa44AY.1200.000149
ORF1ab/nsp1114I114TaTaaCa44AY.290.000063
ORF1ab/nsp1114I114TaTaaCa44AY.330.000267
ORF1ab/nsp1114I114TaTaaCa44AY.470.000124
ORF1ab/nsp1114I114TaTaaCa44AY.60.000165
ORF1ab/nsp1114I114TaTaaCa44AY.610.000419
ORF1ab/nsp1114I114TaTaaCa44AY.750.000224
ORF1ab/nsp1114I114TaTaaCa44AY.950.003044
ORF1ab/nsp1114I114TaTaaCa44B.1.1.1410.008048
ORF1ab/nsp1114I114TaTaaCa44B.1.1.330.001684
ORF1ab/nsp1114I114TaTaaCa44B.1.1770.000053
ORF1ab/nsp1114I114TaTaaCa44B.1.3490.002859
ORF1ab/nsp1114I114TaTaaCa44B.1.5170.001708
ORF1ab/nsp1114I114TaTaaCa33AD.20.000657
ORF1ab/nsp1114I114TaTaaCa33AY.1110.000549
ORF1ab/nsp1114I114TaTaaCa33AY.160.001139
ORF1ab/nsp1114I114TaTaaCa33AY.270.000194
ORF1ab/nsp1114I114TaTaaCa33AY.340.000291
ORF1ab/nsp1114I114TaTaaCa33AY.39.10.000119
ORF1ab/nsp1114I114TaTaaCa33AY.50.000062
ORF1ab/nsp1114I114TaTaaCa33AY.90.000203
ORF1ab/nsp1114I114TaTaaCa33AY.980.000237
ORF1ab/nsp1114I114TaTaaCa33D.20.000225
ORF1ab/nsp1114I114TaTaaCa22A0.000774
ORF1ab/nsp1114I114TaTaaCa22AY.100.00106
ORF1ab/nsp1114I114TaTaaCa22AY.370.000632
ORF1ab/nsp1114I114TaTaaCa22AY.450.000243
ORF1ab/nsp1114I114TaTaaCa22AY.460.000208
ORF1ab/nsp1114I114TaTaaCa22AY.880.001768
ORF1ab/nsp1114I114TaTaaCa22AY.920.000575
ORF1ab/nsp1114I114TaTaaCa22AY.98.10.000097
ORF1ab/nsp1114I114TaTaaCa22B0.000256
ORF1ab/nsp1114I114TaTaaCa22B.1.1.370.000386
ORF1ab/nsp1114I114TaTaaCa22B.1.177.730.001133
ORF1ab/nsp1114I114TaTaaCa22B.1.2210.000142
ORF1ab/nsp1114I114TaTaaCa22B.1.4270.000101
ORF1ab/nsp1114I114TaTaaCa22B.1.4990.002101
ORF1ab/nsp1114I114TaTaaCa22B.1.5090.001732
ORF1ab/nsp1114I114TaTaaCa22B.1.617.10.000258
ORF1ab/nsp1114I114TaTaaCa22C.370.000232
ORF1ab/nsp1114I114TaTaaCa22Q.80.00033
ORF1ab/nsp1114I114TaTaaCa11AY.1160.000287
ORF1ab/nsp1114I114TaTaaCa11AY.116.10.000311
ORF1ab/nsp1114I114TaTaaCa11AY.1170.000085
ORF1ab/nsp1114I114TaTaaCa11AY.120.000316
ORF1ab/nsp1114I114TaTaaCa11AY.1210.000135
ORF1ab/nsp1114I114TaTaaCa11AY.140.000088
ORF1ab/nsp1114I114TaTaaCa11AY.20.000356
ORF1ab/nsp1114I114TaTaaCa11AY.230.00007
ORF1ab/nsp1114I114TaTaaCa11AY.34.10.00051
ORF1ab/nsp1114I114TaTaaCa11AY.380.000499
ORF1ab/nsp1114I114TaTaaCa11AY.46.60.000072
ORF1ab/nsp1114I114TaTaaCa11AY.5.30.000337
ORF1ab/nsp1114I114TaTaaCa11AY.5.40.000277
ORF1ab/nsp1114I114TaTaaCa11AY.570.000656
ORF1ab/nsp1114I114TaTaaCa11AY.700.000209
ORF1ab/nsp1114I114TaTaaCa11AY.740.000116
ORF1ab/nsp1114I114TaTaaCa11AY.75.10.00018
ORF1ab/nsp1114I114TaTaaCa11B.1.1.1350.004695
ORF1ab/nsp1114I114TaTaaCa11B.1.1.2220.000204
ORF1ab/nsp1114I114TaTaaCa11B.1.1.280.000311
ORF1ab/nsp1114I114TaTaaCa11B.1.1.3160.000925
ORF1ab/nsp1114I114TaTaaCa11B.1.1.3980.003226
ORF1ab/nsp1114I114TaTaaCa11B.1.1.4010.066667
ORF1ab/nsp1114I114TaTaaCa11B.1.1580.02381
ORF1ab/nsp1114I114TaTaaCa11B.1.1600.000031
ORF1ab/nsp1114I114TaTaaCa11B.1.177.570.000281
ORF1ab/nsp1114I114TaTaaCa11B.1.177.80.000752
ORF1ab/nsp1114I114TaTaaCa11B.1.177.860.000183
ORF1ab/nsp1114I114TaTaaCa11B.1.2400.000216
ORF1ab/nsp1114I114TaTaaCa11B.1.2470.014925
ORF1ab/nsp1114I114TaTaaCa11B.1.258.140.00098
ORF1ab/nsp1114I114TaTaaCa11B.1.360.000146
ORF1ab/nsp1114I114TaTaaCa11B.1.36.310.001751
ORF1ab/nsp1114I114TaTaaCa11B.1.3610.001289
ORF1ab/nsp1114I114TaTaaCa11B.1.3670.000792
ORF1ab/nsp1114I114TaTaaCa11B.1.3910.001127
ORF1ab/nsp1114I114TaTaaCa11B.1.4080.00369
ORF1ab/nsp1114I114TaTaaCa11B.1.4160.001269
ORF1ab/nsp1114I114TaTaaCa11B.1.440.008333
ORF1ab/nsp1114I114TaTaaCa11B.1.4590.004082
ORF1ab/nsp1114I114TaTaaCa11B.1.466.20.000391
ORF1ab/nsp1114I114TaTaaCa11B.1.4680.005714
ORF1ab/nsp1114I114TaTaaCa11B.1.5680.001111
ORF1ab/nsp1114I114TaTaaCa11B.1.5820.000491
ORF1ab/nsp1114I114TaTaaCa11B.1.6200.000946
ORF1ab/nsp1114I114TaTaaCa11B.1.6250.002353
ORF1ab/nsp1114I114TaTaaCa11B.30.000831
ORF1ab/nsp1114I114TaTaaCa11C.160.00106
ORF1ab/nsp1114I114TaTaaCa11C.360.000911
ORF1ab/nsp1114I114TaTaaCa11P.1.120.000484
ORF1ab/nsp1114I114TaTaaCa11P.1.70.000319
ORF1ab/nsp1114I114TaTaaCa11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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