CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = V158V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	158	V158V		syn	gtG	gtT	2930	2324	0.793174	28745-28747
N	158	V158V		syn	gtG	gtA	2930	476	0.162457	28745-28747
N	158	V158V		syn	gtG	gtC	2930	130	0.0443686	28745-28747

Details of the mutation V158V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	158	V158V	gtG	gtT	2324	2930	All	0.000444
N	158	V158V	gtG	gtA	476	2930	All	0.000091
N	158	V158V	gtG	gtC	130	2930	All	0.000025
N	158	V158V	gtG	gtT	571	727	B.1.1.7	0.000511
N	158	V158V	gtG	gtA	150	727	B.1.1.7	0.000134
N	158	V158V	gtG	gtC	6	727	B.1.1.7	0.000005
N	158	V158V	gtG	gtT	232	232	B.1.146	0.983051
N	158	V158V	gtG	gtT	192	192	AY.7.2	0.107383
N	158	V158V	gtG	gtT	178	183	AY.44	0.001083
N	158	V158V	gtG	gtA	5	183	AY.44	0.00003
N	158	V158V	gtG	gtT	155	178	AY.4	0.000241
N	158	V158V	gtG	gtC	15	178	AY.4	0.000023
N	158	V158V	gtG	gtA	8	178	AY.4	0.000012
N	158	V158V	gtG	gtA	144	144	AY.9	0.009734
N	158	V158V	gtG	gtT	138	143	B.1.221	0.009803
N	158	V158V	gtG	gtA	5	143	B.1.221	0.000355
N	158	V158V	gtG	gtT	97	100	B.1.1	0.00176
N	158	V158V	gtG	gtA	2	100	B.1.1	0.000036
N	158	V158V	gtG	gtC	1	100	B.1.1	0.000018
N	158	V158V	gtG	gtT	57	98	B.1.617.2	0.000215
N	158	V158V	gtG	gtA	23	98	B.1.617.2	0.000087
N	158	V158V	gtG	gtC	18	98	B.1.617.2	0.000068
N	158	V158V	gtG	gtT	77	77	AY.33	0.005142
N	158	V158V	gtG	gtT	63	65	B.1.1.519	0.002502
N	158	V158V	gtG	gtA	2	65	B.1.1.519	0.000079
N	158	V158V	gtG	gtC	43	64	AY.25	0.000259
N	158	V158V	gtG	gtT	20	64	AY.25	0.00012
N	158	V158V	gtG	gtA	1	64	AY.25	0.000006
N	158	V158V	gtG	gtT	40	64	AY.43	0.000177
N	158	V158V	gtG	gtA	24	64	AY.43	0.000106
N	158	V158V	gtG	gtT	52	63	B.1	0.000476
N	158	V158V	gtG	gtA	9	63	B.1	0.000082
N	158	V158V	gtG	gtC	2	63	B.1	0.000018
N	158	V158V	gtG	gtT	32	35	AY.3	0.000318
N	158	V158V	gtG	gtA	3	35	AY.3	0.00003
N	158	V158V	gtG	gtT	32	35	AY.4.2	0.000694
N	158	V158V	gtG	gtA	3	35	AY.4.2	0.000065
N	158	V158V	gtG	gtT	23	27	AY.103	0.000143
N	158	V158V	gtG	gtA	3	27	AY.103	0.000019
N	158	V158V	gtG	gtC	1	27	AY.103	0.000006
N	158	V158V	gtG	gtT	22	22	AY.26	0.000623
N	158	V158V	gtG	gtT	22	22	B.1.1.231	0.068111
N	158	V158V	gtG	gtT	15	21	AY.102	0.000398
N	158	V158V	gtG	gtA	6	21	AY.102	0.000159
N	158	V158V	gtG	gtT	21	21	AY.5.3	0.007085
N	158	V158V	gtG	gtT	10	19	B.1.2	0.000088
N	158	V158V	gtG	gtA	9	19	B.1.2	0.000079
N	158	V158V	gtG	gtA	10	19	B.1.526	0.000235
N	158	V158V	gtG	gtT	9	19	B.1.526	0.000212
N	158	V158V	gtG	gtC	16	16	A.2.5.1	0.076923
N	158	V158V	gtG	gtT	15	15	B.1.258.17	0.00156
N	158	V158V	gtG	gtC	10	14	AY.42	0.000402
N	158	V158V	gtG	gtT	4	14	AY.42	0.000161
N	158	V158V	gtG	gtT	12	12	AY.34	0.001164
N	158	V158V	gtG	gtT	11	12	B.1.177	0.000145
N	158	V158V	gtG	gtA	1	12	B.1.177	0.000013
N	158	V158V	gtG	gtT	11	11	AY.23	0.000767
N	158	V158V	gtG	gtT	10	11	P.1	0.000158
N	158	V158V	gtG	gtC	1	11	P.1	0.000016
N	158	V158V	gtG	gtA	9	11	P.1.15	0.002091
N	158	V158V	gtG	gtT	2	11	P.1.15	0.000465
N	158	V158V	gtG	gtA	10	10	AY.46.4	0.001645
N	158	V158V	gtG	gtC	6	10	AY.46.5	0.00119
N	158	V158V	gtG	gtT	4	10	AY.46.5	0.000794
N	158	V158V	gtG	gtT	7	9	AY.75	0.000392
N	158	V158V	gtG	gtA	2	9	AY.75	0.000112
N	158	V158V	gtG	gtT	4	8	AY.118	0.000251
N	158	V158V	gtG	gtC	3	8	AY.118	0.000188
N	158	V158V	gtG	gtA	1	8	AY.118	0.000063
N	158	V158V	gtG	gtA	4	8	AY.39	0.000099
N	158	V158V	gtG	gtT	4	8	AY.39	0.000099
N	158	V158V	gtG	gtT	8	8	B.1.1.193	0.888889
N	158	V158V	gtG	gtT	8	8	B.1.1.33	0.003367
N	158	V158V	gtG	gtA	5	8	B.1.351	0.000149
N	158	V158V	gtG	gtT	3	8	B.1.351	0.000089
N	158	V158V	gtG	gtT	6	7	B.1.36	0.000875
N	158	V158V	gtG	gtA	1	7	B.1.36	0.000146
N	158	V158V	gtG	gtT	6	6	AY.4.2.1	0.000894
N	158	V158V	gtG	gtT	5	6	AY.46	0.00052
N	158	V158V	gtG	gtA	1	6	AY.46	0.000104
N	158	V158V	gtG	gtC	5	6	AY.70	0.001043
N	158	V158V	gtG	gtA	1	6	AY.70	0.000209
N	158	V158V	gtG	gtT	6	6	B.1.1.70	0.002046
N	158	V158V	gtG	gtT	3	6	B.1.258	0.0002
N	158	V158V	gtG	gtA	3	6	B.1.258	0.0002
N	158	V158V	gtG	gtT	5	5	AY.100	0.00023
N	158	V158V	gtG	gtT	4	5	AY.119	0.000141
N	158	V158V	gtG	gtA	1	5	AY.119	0.000035
N	158	V158V	gtG	gtT	3	5	AY.9.1	0.000251
N	158	V158V	gtG	gtA	2	5	AY.9.1	0.000167
N	158	V158V	gtG	gtT	4	4	AY.4.4	0.001637
N	158	V158V	gtG	gtT	4	4	B.1.1.216	0.003562
N	158	V158V	gtG	gtT	4	4	B.1.1.419	0.02963
N	158	V158V	gtG	gtT	4	4	B.1.160	0.000125
N	158	V158V	gtG	gtT	3	4	B.1.243	0.000209
N	158	V158V	gtG	gtA	1	4	B.1.243	0.00007
N	158	V158V	gtG	gtT	4	4	B.1.438.1	0.000429
N	158	V158V	gtG	gtT	4	4	B.1.525	0.000453
N	158	V158V	gtG	gtA	3	3	AY.30	0.001187
N	158	V158V	gtG	gtT	3	3	AY.32	0.001597
N	158	V158V	gtG	gtA	2	3	AY.47	0.000062
N	158	V158V	gtG	gtT	1	3	AY.47	0.000031
N	158	V158V	gtG	gtT	2	3	AY.5	0.000041
N	158	V158V	gtG	gtA	1	3	AY.5	0.000021
N	158	V158V	gtG	gtT	3	3	AY.79	0.003632
N	158	V158V	gtG	gtT	3	3	B	0.000383
N	158	V158V	gtG	gtT	3	3	B.1.1.333	0.003229
N	158	V158V	gtG	gtT	3	3	B.1.470	0.004213
N	158	V158V	gtG	gtT	2	2	A	0.000774
N	158	V158V	gtG	gtT	2	2	AU.2	0.004843
N	158	V158V	gtG	gtT	1	2	AY.101	0.00049
N	158	V158V	gtG	gtA	1	2	AY.101	0.00049
N	158	V158V	gtG	gtT	1	2	AY.13	0.000161
N	158	V158V	gtG	gtA	1	2	AY.13	0.000161
N	158	V158V	gtG	gtA	2	2	AY.14	0.000176
N	158	V158V	gtG	gtT	2	2	AY.20	0.000078
N	158	V158V	gtG	gtT	2	2	AY.45	0.000243
N	158	V158V	gtG	gtT	2	2	AY.46.6	0.000144
N	158	V158V	gtG	gtT	2	2	AY.61	0.00021
N	158	V158V	gtG	gtT	2	2	AY.67	0.000929
N	158	V158V	gtG	gtA	1	2	B.1.1.214	0.000055
N	158	V158V	gtG	gtT	1	2	B.1.1.214	0.000055
N	158	V158V	gtG	gtT	2	2	B.1.1.416	0.00181
N	158	V158V	gtG	gtT	2	2	B.1.177.7	0.00033
N	158	V158V	gtG	gtA	2	2	B.1.596	0.000174
N	158	V158V	gtG	gtT	2	2	B.1.617.1	0.000258
N	158	V158V	gtG	gtT	2	2	R.1	0.00018
N	158	V158V	gtG	gtA	1	1	AY.10	0.00053
N	158	V158V	gtG	gtT	1	1	AY.106	0.000335
N	158	V158V	gtG	gtT	1	1	AY.117	0.000085
N	158	V158V	gtG	gtT	1	1	AY.120	0.000037
N	158	V158V	gtG	gtT	1	1	AY.120.1	0.000321
N	158	V158V	gtG	gtT	1	1	AY.121	0.000135
N	158	V158V	gtG	gtT	1	1	AY.16	0.00038
N	158	V158V	gtG	gtT	1	1	AY.16.1	0.00047
N	158	V158V	gtG	gtT	1	1	AY.19	0.00114
N	158	V158V	gtG	gtC	1	1	AY.22	0.002092
N	158	V158V	gtG	gtT	1	1	AY.29	0.000016
N	158	V158V	gtG	gtT	1	1	AY.34.1	0.00051
N	158	V158V	gtG	gtT	1	1	AY.38	0.000499
N	158	V158V	gtG	gtT	1	1	AY.39.1	0.00004
N	158	V158V	gtG	gtA	1	1	AY.4.1	0.000737
N	158	V158V	gtG	gtA	1	1	AY.4.5	0.000107
N	158	V158V	gtG	gtT	1	1	AY.46.2	0.000635
N	158	V158V	gtG	gtA	1	1	AY.5.4	0.000277
N	158	V158V	gtG	gtA	1	1	AY.74	0.000116
N	158	V158V	gtG	gtA	1	1	AY.75.1	0.00018
N	158	V158V	gtG	gtA	1	1	AY.8	0.000606
N	158	V158V	gtG	gtT	1	1	AY.80	0.001129
N	158	V158V	gtG	gtT	1	1	AY.84	0.000437
N	158	V158V	gtG	gtT	1	1	AY.85	0.000427
N	158	V158V	gtG	gtT	1	1	AY.9.2	0.000037
N	158	V158V	gtG	gtA	1	1	AY.96	0.002075
N	158	V158V	gtG	gtT	1	1	AY.97	0.001701
N	158	V158V	gtG	gtT	1	1	AY.98.1	0.000048
N	158	V158V	gtG	gtT	1	1	B.1.1.236	0.006897
N	158	V158V	gtG	gtT	1	1	B.1.1.237	0.005405
N	158	V158V	gtG	gtT	1	1	B.1.1.316	0.000925
N	158	V158V	gtG	gtT	1	1	B.1.1.317	0.000412
N	158	V158V	gtG	gtT	1	1	B.1.1.39	0.00051
N	158	V158V	gtG	gtT	1	1	B.1.1.411	0.014706
N	158	V158V	gtG	gtT	1	1	B.1.1.57	0.011494
N	158	V158V	gtG	gtT	1	1	B.1.111	0.001175
N	158	V158V	gtG	gtT	1	1	B.1.160.9	0.007194
N	158	V158V	gtG	gtT	1	1	B.1.169	0.014925
N	158	V158V	gtG	gtT	1	1	B.1.177.4	0.000211
N	158	V158V	gtG	gtT	1	1	B.1.177.65	0.000665
N	158	V158V	gtG	gtT	1	1	B.1.236	0.002053
N	158	V158V	gtG	gtC	1	1	B.1.305	0.002151
N	158	V158V	gtG	gtT	1	1	B.1.311	0.000275
N	158	V158V	gtG	gtA	1	1	B.1.321	0.034483
N	158	V158V	gtG	gtT	1	1	B.1.350	0.002933
N	158	V158V	gtG	gtT	1	1	B.1.351.2	0.000303
N	158	V158V	gtG	gtA	1	1	B.1.36.29	0.000517
N	158	V158V	gtG	gtT	1	1	B.1.36.8	0.001
N	158	V158V	gtG	gtT	1	1	B.1.362	0.001541
N	158	V158V	gtG	gtT	1	1	B.1.375	0.00082
N	158	V158V	gtG	gtT	1	1	B.1.398	0.002976
N	158	V158V	gtG	gtT	1	1	B.1.427	0.00005
N	158	V158V	gtG	gtT	1	1	B.1.429	0.000024
N	158	V158V	gtG	gtA	1	1	B.1.468	0.005714
N	158	V158V	gtG	gtT	1	1	B.1.497	0.000315
N	158	V158V	gtG	gtT	1	1	B.1.509	0.000866
N	158	V158V	gtG	gtA	1	1	B.1.567	0.003333
N	158	V158V	gtG	gtT	1	1	B.1.595	0.000261
N	158	V158V	gtG	gtT	1	1	B.1.600	0.005848
N	158	V158V	gtG	gtT	1	1	B.1.620	0.000946
N	158	V158V	gtG	gtC	1	1	B.1.636	0.006711
N	158	V158V	gtG	gtT	1	1	B.1.637	0.000073
N	158	V158V	gtG	gtT	1	1	B.1.9.1	0.032258
N	158	V158V	gtG	gtT	1	1	B.4.8	0.071429
N	158	V158V	gtG	gtA	1	1	C.1.2	0.004255
N	158	V158V	gtG	gtT	1	1	C.23	0.005814
N	158	V158V	gtG	gtT	1	1	C.37	0.000116
N	158	V158V	gtG	gtT	1	1	C.8	0.004464
N	158	V158V	gtG	gtT	1	1	N.9	0.005952
N	158	V158V	gtG	gtT	1	1	P.1.14	0.000048
N	158	V158V	gtG	gtT	1	1	P.1.7	0.000319
N	158	V158V	gtG	gtA	1	1	Q.3	0.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.