CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 206 | S206F | nonsyn | tCt | tTt | 5670 | 5668 | 0.999647 | 28889-28891 | |
N | 206 | S206F | nonsyn | tCT | tTC | 5670 | 2 | 0.000352734 | 28889-28891 |
Details of the mutation S206F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 206 | S206F | tCt | tTt | 5668 | 5670 | All | 0.001084 |
N | 206 | S206F | tCT | tTC | 2 | 5670 | All | 0 |
N | 206 | S206F | tCt | tTt | 2317 | 2317 | B.1.517 | 0.989325 |
N | 206 | S206F | tCt | tTt | 972 | 972 | B.1.436 | 1 |
N | 206 | S206F | tCt | tTt | 446 | 446 | B.1.324 | 0.715891 |
N | 206 | S206F | tCt | tTt | 310 | 310 | B.1.617.2 | 0.001167 |
N | 206 | S206F | tCt | tTt | 218 | 219 | B.1 | 0.001997 |
N | 206 | S206F | tCT | tTC | 1 | 219 | B.1 | 0.000009 |
N | 206 | S206F | tCt | tTt | 204 | 204 | AY.4 | 0.000318 |
N | 206 | S206F | tCt | tTt | 189 | 189 | B.1.517.1 | 0.994737 |
N | 206 | S206F | tCt | tTt | 84 | 84 | AY.103 | 0.000522 |
N | 206 | S206F | tCt | tTt | 76 | 76 | B.1.1 | 0.001379 |
N | 206 | S206F | tCt | tTt | 69 | 69 | AY.26 | 0.001953 |
N | 206 | S206F | tCt | tTt | 52 | 52 | AY.43 | 0.00023 |
N | 206 | S206F | tCt | tTt | 52 | 52 | AY.44 | 0.000317 |
N | 206 | S206F | tCt | tTt | 43 | 43 | AY.23 | 0.002999 |
N | 206 | S206F | tCt | tTt | 40 | 40 | AY.3 | 0.000398 |
N | 206 | S206F | tCt | tTt | 34 | 34 | B.1.1.7 | 0.00003 |
N | 206 | S206F | tCt | tTt | 31 | 31 | AY.25 | 0.000186 |
N | 206 | S206F | tCt | tTt | 27 | 27 | AY.61 | 0.002829 |
N | 206 | S206F | tCt | tTt | 25 | 25 | B.1.2 | 0.00022 |
N | 206 | S206F | tCt | tTt | 19 | 19 | AY.39 | 0.00047 |
N | 206 | S206F | tCt | tTt | 17 | 17 | AY.52 | 0.013844 |
N | 206 | S206F | tCt | tTt | 16 | 16 | AY.113 | 0.002278 |
N | 206 | S206F | tCt | tTt | 16 | 16 | AY.118 | 0.001002 |
N | 206 | S206F | tCt | tTt | 16 | 16 | AY.119 | 0.000565 |
N | 206 | S206F | tCt | tTt | 15 | 15 | AY.100 | 0.00069 |
N | 206 | S206F | tCt | tTt | 14 | 14 | AY.29 | 0.000221 |
N | 206 | S206F | tCt | tTt | 13 | 13 | AY.20 | 0.000505 |
N | 206 | S206F | tCt | tTt | 12 | 12 | AY.74 | 0.001388 |
N | 206 | S206F | tCt | tTt | 11 | 11 | AY.117 | 0.00093 |
N | 206 | S206F | tCt | tTt | 11 | 11 | AY.75 | 0.000616 |
N | 206 | S206F | tCt | tTt | 10 | 10 | AY.47 | 0.000311 |
N | 206 | S206F | tCt | tTt | 9 | 9 | AY.120 | 0.000335 |
N | 206 | S206F | tCt | tTt | 8 | 8 | AY.14 | 0.000704 |
N | 206 | S206F | tCt | tTt | 8 | 8 | AY.57 | 0.005249 |
N | 206 | S206F | tCt | tTt | 8 | 8 | AY.6 | 0.000329 |
N | 206 | S206F | tCt | tTt | 7 | 7 | AY.102 | 0.000186 |
N | 206 | S206F | tCt | tTt | 7 | 7 | AY.95 | 0.005327 |
N | 206 | S206F | tCt | tTt | 7 | 7 | AY.98 | 0.000553 |
N | 206 | S206F | tCt | tTt | 7 | 7 | B.1.37 | 0.102941 |
N | 206 | S206F | tCt | tTt | 6 | 6 | AY.33 | 0.000401 |
N | 206 | S206F | tCt | tTt | 6 | 6 | AY.4.2 | 0.00013 |
N | 206 | S206F | tCt | tTt | 6 | 6 | AY.42 | 0.000241 |
N | 206 | S206F | tCt | tTt | 6 | 6 | AY.64 | 0.003571 |
N | 206 | S206F | tCt | tTt | 6 | 6 | AZ.2 | 0.004926 |
N | 206 | S206F | tCt | tTt | 6 | 6 | B.1.1.214 | 0.000333 |
N | 206 | S206F | tCt | tTt | 6 | 6 | B.1.111 | 0.007051 |
N | 206 | S206F | tCt | tTt | 6 | 6 | B.1.617.1 | 0.000774 |
N | 206 | S206F | tCt | tTt | 5 | 5 | AY.13 | 0.000805 |
N | 206 | S206F | tCt | tTt | 5 | 5 | AY.27 | 0.000324 |
N | 206 | S206F | tCt | tTt | 5 | 5 | AY.3.1 | 0.000426 |
N | 206 | S206F | tCt | tTt | 5 | 5 | AY.5 | 0.000103 |
N | 206 | S206F | tCt | tTt | 5 | 5 | AY.62 | 0.002179 |
N | 206 | S206F | tCt | tTt | 4 | 5 | AY.9.2 | 0.000147 |
N | 206 | S206F | tCT | tTC | 1 | 5 | AY.9.2 | 0.000037 |
N | 206 | S206F | tCt | tTt | 5 | 5 | B.1.1.519 | 0.000199 |
N | 206 | S206F | tCt | tTt | 5 | 5 | B.1.596 | 0.000436 |
N | 206 | S206F | tCt | tTt | 5 | 5 | P.1.12 | 0.00242 |
N | 206 | S206F | tCt | tTt | 4 | 4 | AY.16.1 | 0.00188 |
N | 206 | S206F | tCt | tTt | 4 | 4 | AY.35 | 0.000932 |
N | 206 | S206F | tCt | tTt | 4 | 4 | AY.9 | 0.00027 |
N | 206 | S206F | tCt | tTt | 4 | 4 | AY.98.1 | 0.000194 |
N | 206 | S206F | tCt | tTt | 4 | 4 | B.1.1.153 | 0.004381 |
N | 206 | S206F | tCt | tTt | 4 | 4 | B.1.1.63 | 0.001543 |
N | 206 | S206F | tCt | tTt | 4 | 4 | B.1.609 | 0.001918 |
N | 206 | S206F | tCt | tTt | 3 | 3 | AY.114 | 0.000693 |
N | 206 | S206F | tCt | tTt | 3 | 3 | AY.121 | 0.000406 |
N | 206 | S206F | tCt | tTt | 3 | 3 | AY.24 | 0.001293 |
N | 206 | S206F | tCt | tTt | 3 | 3 | AY.45 | 0.000365 |
N | 206 | S206F | tCt | tTt | 3 | 3 | B.1.1.318 | 0.000905 |
N | 206 | S206F | tCt | tTt | 3 | 3 | B.1.378 | 0.020548 |
N | 206 | S206F | tCt | tTt | 3 | 3 | B.1.473 | 0.057692 |
N | 206 | S206F | tCt | tTt | 2 | 2 | A.1 | 0.000564 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AD.2 | 0.000438 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.12 | 0.000632 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.15 | 0.004444 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.2 | 0.000712 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.31 | 0.037037 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.36 | 0.000296 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.37 | 0.000632 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.4.2.1 | 0.000298 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.4.5 | 0.000215 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.46 | 0.000208 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.46.1 | 0.002053 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.51 | 0.001818 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.55 | 0.001835 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.63 | 0.000774 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.69 | 0.000373 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.75.1 | 0.000361 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.79 | 0.002421 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.84 | 0.000875 |
N | 206 | S206F | tCt | tTt | 2 | 2 | AY.99 | 0.002099 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.1.227 | 0.008696 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.1.353 | 0.041667 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.1.448 | 0.004065 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.1.464 | 0.002946 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.580 | 0.00813 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.593 | 0.021739 |
N | 206 | S206F | tCt | tTt | 2 | 2 | B.1.619.1 | 0.001283 |
N | 206 | S206F | tCt | tTt | 2 | 2 | Q.8 | 0.00033 |
N | 206 | S206F | tCt | tTt | 1 | 1 | 0.055556 | |
N | 206 | S206F | tCt | tTt | 1 | 1 | A.21 | 0.00277 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.116.1 | 0.000311 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.16 | 0.00038 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.28 | 0.00189 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.39.1 | 0.00004 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.46.2 | 0.000635 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.46.4 | 0.000165 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.49 | 0.003195 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.68 | 0.000274 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.7.1 | 0.000113 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.71 | 0.000475 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.83 | 0.001724 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.85 | 0.000427 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.86 | 0.00083 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.87 | 0.000833 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.92 | 0.000287 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.94 | 0.000443 |
N | 206 | S206F | tCt | tTt | 1 | 1 | AY.99.2 | 0.000092 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B | 0.000128 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.189 | 0.001513 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.25 | 0.000569 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.277 | 0.000759 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.28 | 0.000311 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.284 | 0.000107 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.31 | 0.066667 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.317 | 0.000412 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.1.419 | 0.007407 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.143 | 0.021277 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.160.30 | 0.002976 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.177.58 | 0.001332 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.177.81 | 0.000189 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.177.83 | 0.001481 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.218 | 0.005155 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.221 | 0.000071 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.311 | 0.000275 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.320 | 0.001245 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.36.17 | 0.000494 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.362 | 0.001541 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.369 | 0.000285 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.465 | 0.003802 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.509 | 0.000866 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.526 | 0.000024 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.533 | 0.009615 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.564 | 0.000426 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.1.612 | 0.002653 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.4.1 | 0.018868 |
N | 206 | S206F | tCt | tTt | 1 | 1 | B.40 | 0.000364 |
N | 206 | S206F | tCt | tTt | 1 | 1 | D.2 | 0.000075 |
N | 206 | S206F | tCt | tTt | 1 | 1 | P.1 | 0.000016 |
N | 206 | S206F | tCt | tTt | 1 | 1 | P.1.16 | 0.000374 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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