CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 180 | S180I | nonsyn | aGt | aTt | 1635 | 1634 | 0.999388 | 28811-28813 | |
N | 180 | S180I | nonsyn | aGT | aTC | 1635 | 1 | 0.000611621 | 28811-28813 |
Details of the mutation S180I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 180 | S180I | aGt | aTt | 1634 | 1635 | All | 0.000313 |
N | 180 | S180I | aGT | aTC | 1 | 1635 | All | 0 |
N | 180 | S180I | aGt | aTt | 193 | 193 | B.1.258 | 0.012844 |
N | 180 | S180I | aGt | aTt | 149 | 149 | AY.4 | 0.000232 |
N | 180 | S180I | aGt | aTt | 116 | 116 | A.1 | 0.032694 |
N | 180 | S180I | aGt | aTt | 115 | 115 | AY.43 | 0.00051 |
N | 180 | S180I | aGt | aTt | 108 | 109 | B.1.1.7 | 0.000097 |
N | 180 | S180I | aGT | aTC | 1 | 109 | B.1.1.7 | 0.000001 |
N | 180 | S180I | aGt | aTt | 108 | 108 | B.1 | 0.000989 |
N | 180 | S180I | aGt | aTt | 79 | 79 | AY.25 | 0.000475 |
N | 180 | S180I | aGt | aTt | 68 | 68 | B.1.617.2 | 0.000256 |
N | 180 | S180I | aGt | aTt | 46 | 46 | AY.26 | 0.001302 |
N | 180 | S180I | aGt | aTt | 38 | 38 | B.1.1.519 | 0.001509 |
N | 180 | S180I | aGt | aTt | 36 | 36 | AY.54 | 0.003432 |
N | 180 | S180I | aGt | aTt | 24 | 24 | AY.103 | 0.000149 |
N | 180 | S180I | aGt | aTt | 22 | 22 | AY.45 | 0.002677 |
N | 180 | S180I | aGt | aTt | 20 | 20 | AY.29 | 0.000315 |
N | 180 | S180I | aGt | aTt | 20 | 20 | B.1.358 | 1 |
N | 180 | S180I | aGt | aTt | 19 | 19 | B.1.160 | 0.000593 |
N | 180 | S180I | aGt | aTt | 17 | 17 | AY.42 | 0.000684 |
N | 180 | S180I | aGt | aTt | 17 | 17 | AY.6 | 0.000699 |
N | 180 | S180I | aGt | aTt | 17 | 17 | B.1.1 | 0.000308 |
N | 180 | S180I | aGt | aTt | 15 | 15 | AY.109 | 0.011095 |
N | 180 | S180I | aGt | aTt | 15 | 15 | AY.67 | 0.006964 |
N | 180 | S180I | aGt | aTt | 15 | 15 | B.1.2 | 0.000132 |
N | 180 | S180I | aGt | aTt | 12 | 12 | AY.44 | 0.000073 |
N | 180 | S180I | aGt | aTt | 12 | 12 | B.1.1.112 | 0.705882 |
N | 180 | S180I | aGt | aTt | 11 | 11 | AY.7 | 0.002156 |
N | 180 | S180I | aGt | aTt | 11 | 11 | B.1.617.1 | 0.001419 |
N | 180 | S180I | aGt | aTt | 11 | 11 | P.1 | 0.000173 |
N | 180 | S180I | aGt | aTt | 10 | 10 | B.3 | 0.008306 |
N | 180 | S180I | aGt | aTt | 9 | 9 | AY.5 | 0.000186 |
N | 180 | S180I | aGt | aTt | 9 | 9 | AY.61 | 0.000943 |
N | 180 | S180I | aGt | aTt | 9 | 9 | B.1.147 | 0.006803 |
N | 180 | S180I | aGt | aTt | 8 | 8 | B.1.1.302 | 0.016598 |
N | 180 | S180I | aGt | aTt | 8 | 8 | B.1.177 | 0.000105 |
N | 180 | S180I | aGt | aTt | 7 | 7 | AC.1 | 0.259259 |
N | 180 | S180I | aGt | aTt | 7 | 7 | AY.119 | 0.000247 |
N | 180 | S180I | aGt | aTt | 7 | 7 | B.1.177.86 | 0.001284 |
N | 180 | S180I | aGt | aTt | 7 | 7 | B.1.351 | 0.000208 |
N | 180 | S180I | aGt | aTt | 7 | 7 | P.1.17 | 0.001132 |
N | 180 | S180I | aGt | aTt | 6 | 6 | AY.3 | 0.00006 |
N | 180 | S180I | aGt | aTt | 6 | 6 | B.1.232 | 0.003224 |
N | 180 | S180I | aGt | aTt | 6 | 6 | B.1.429 | 0.000141 |
N | 180 | S180I | aGt | aTt | 6 | 6 | C.37 | 0.000696 |
N | 180 | S180I | aGt | aTt | 5 | 5 | AY.100 | 0.00023 |
N | 180 | S180I | aGt | aTt | 5 | 5 | AY.71 | 0.002375 |
N | 180 | S180I | aGt | aTt | 5 | 5 | B.1.1.311 | 0.001791 |
N | 180 | S180I | aGt | aTt | 5 | 5 | B.1.595 | 0.001305 |
N | 180 | S180I | aGt | aTt | 5 | 5 | D.2 | 0.000375 |
N | 180 | S180I | aGt | aTt | 4 | 4 | AY.102 | 0.000106 |
N | 180 | S180I | aGt | aTt | 4 | 4 | AY.16.1 | 0.00188 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.1.17 | 0.066667 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.160.10 | 0.032258 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.466.2 | 0.001565 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.474 | 0.007605 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.526 | 0.000094 |
N | 180 | S180I | aGt | aTt | 4 | 4 | B.1.609 | 0.001918 |
N | 180 | S180I | aGt | aTt | 3 | 3 | A.3 | 0.006289 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.13 | 0.000483 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.14 | 0.000264 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.36 | 0.000445 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.37 | 0.000948 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.4.2.1 | 0.000447 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.55 | 0.002752 |
N | 180 | S180I | aGt | aTt | 3 | 3 | AY.9 | 0.000203 |
N | 180 | S180I | aGt | aTt | 3 | 3 | B.1.1.214 | 0.000166 |
N | 180 | S180I | aGt | aTt | 3 | 3 | B.1.1.222 | 0.000612 |
N | 180 | S180I | aGt | aTt | 3 | 3 | B.1.413 | 0.012766 |
N | 180 | S180I | aGt | aTt | 3 | 3 | B.1.427 | 0.000151 |
N | 180 | S180I | aGt | aTt | 3 | 3 | B.1.590 | 0.013636 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.117 | 0.000169 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.33 | 0.000134 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.35 | 0.000466 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.39 | 0.000049 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.4.2 | 0.000043 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.70 | 0.000417 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.98.1 | 0.000097 |
N | 180 | S180I | aGt | aTt | 2 | 2 | AY.99.2 | 0.000184 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.1.318 | 0.000604 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.1.39 | 0.001019 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.1.50 | 0.001358 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.1.70 | 0.000682 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.438.1 | 0.000215 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.497 | 0.00063 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.621 | 0.000177 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.1.637 | 0.000146 |
N | 180 | S180I | aGt | aTt | 2 | 2 | B.42 | 0.066667 |
N | 180 | S180I | aGt | aTt | 2 | 2 | C.16 | 0.002121 |
N | 180 | S180I | aGt | aTt | 2 | 2 | C.35 | 0.001548 |
N | 180 | S180I | aGt | aTt | 2 | 2 | P.1.10 | 0.000539 |
N | 180 | S180I | aGt | aTt | 2 | 2 | Q.1 | 0.000253 |
N | 180 | S180I | aGt | aTt | 2 | 2 | R.1 | 0.00018 |
N | 180 | S180I | aGt | aTt | 1 | 1 | A | 0.000387 |
N | 180 | S180I | aGt | aTt | 1 | 1 | A.2.5 | 0.000499 |
N | 180 | S180I | aGt | aTt | 1 | 1 | A.5 | 0.001923 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AU.2 | 0.002421 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AW.1 | 0.003049 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.107 | 0.000466 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.108 | 0.001103 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.111 | 0.000183 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.116.1 | 0.000311 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.12 | 0.000316 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.121 | 0.000135 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.16 | 0.00038 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.2 | 0.000356 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.24 | 0.000431 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.29.1 | 0.000221 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.30 | 0.000396 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.4.5 | 0.000107 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.40 | 0.000964 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.46 | 0.000104 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.46.4 | 0.000165 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.46.6 | 0.000072 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.47 | 0.000031 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.53 | 0.000288 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.72 | 0.001361 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.75.1 | 0.00018 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.77 | 0.001127 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.9.2 | 0.000037 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AY.98 | 0.000079 |
N | 180 | S180I | aGt | aTt | 1 | 1 | AZ.2 | 0.000821 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B | 0.000128 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.1 | 0.000327 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.207 | 0.001182 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.216 | 0.00089 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.232 | 0.001815 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.284 | 0.000107 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.448 | 0.002033 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.459 | 0.015385 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.1.462 | 0.008621 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.110.1 | 0.1 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.113 | 0.015625 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.157 | 0.002985 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.169 | 0.014925 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.177.30 | 0.002513 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.177.63 | 0.002703 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.177.8 | 0.000752 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.258.14 | 0.00098 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.3 | 0.002618 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.350 | 0.002933 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.351.2 | 0.000303 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.36 | 0.000146 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.36.24 | 0.006173 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.382 | 0.008929 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.396 | 0.000706 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.479 | 0.038462 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.492 | 0.007042 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.499 | 0.00105 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.504 | 0.03125 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.521 | 0.004975 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.1.612 | 0.002653 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.28 | 0.003279 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.39 | 0.002331 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.40 | 0.000364 |
N | 180 | S180I | aGt | aTt | 1 | 1 | B.6 | 0.00091 |
N | 180 | S180I | aGt | aTt | 1 | 1 | N.9 | 0.005952 |
N | 180 | S180I | aGt | aTt | 1 | 1 | P.1.14 | 0.000048 |
N | 180 | S180I | aGt | aTt | 1 | 1 | P.1.15 | 0.000232 |
N | 180 | S180I | aGt | aTt | 1 | 1 | P.1.2 | 0.001156 |
N | 180 | S180I | aGt | aTt | 1 | 1 | Q.8 | 0.000165 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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