CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = R385K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	385	R385K		nonsyn	aGa	aAa	18584	18577	0.999623	29426-29428
N	385	R385K		nonsyn	aGA	aAG	18584	7	0.000376668	29426-29428

Details of the mutation R385K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	385	R385K	aGa	aAa	18577	18584	All	0.003553
N	385	R385K	aGA	aAG	7	18584	All	0.000001
N	385	R385K	aGa	aAa	10576	10581	B.1.617.2	0.039823
N	385	R385K	aGA	aAG	5	10581	B.1.617.2	0.000019
N	385	R385K	aGa	aAa	3224	3224	B.1.160	0.100549
N	385	R385K	aGa	aAa	2426	2426	AY.30	0.960032
N	385	R385K	aGa	aAa	758	758	AY.40	0.730955
N	385	R385K	aGa	aAa	206	206	B.1.160.23	0.995169
N	385	R385K	aGa	aAa	140	140	B.1.160.22	0.945946
N	385	R385K	aGa	aAa	89	89	AY.43	0.000394
N	385	R385K	aGa	aAa	88	88	B.1	0.000806
N	385	R385K	aGa	aAa	73	73	AY.16.1	0.034305
N	385	R385K	aGa	aAa	72	72	AY.67	0.033426
N	385	R385K	aGa	aAa	66	66	B.1.1.7	0.000059
N	385	R385K	aGa	aAa	64	64	AY.46.5	0.012698
N	385	R385K	aGa	aAa	53	54	AY.31	0.981481
N	385	R385K	aGA	aAG	1	54	AY.31	0.018519
N	385	R385K	aGa	aAa	38	38	AY.13	0.006117
N	385	R385K	aGa	aAa	34	34	AY.56	0.054575
N	385	R385K	aGa	aAa	25	25	AY.75	0.001401
N	385	R385K	aGa	aAa	24	24	AY.44	0.000146
N	385	R385K	aGa	aAa	22	22	AY.59	0.011653
N	385	R385K	aGa	aAa	22	22	AY.65	0.011727
N	385	R385K	aGa	aAa	20	20	AY.54	0.001907
N	385	R385K	aGa	aAa	19	19	AY.39	0.00047
N	385	R385K	aGa	aAa	18	18	AY.9.2	0.000661
N	385	R385K	aGa	aAa	16	16	AY.26	0.000453
N	385	R385K	aGa	aAa	16	16	B.1.214	0.058608
N	385	R385K	aGa	aAa	14	14	AY.75.1	0.002524
N	385	R385K	aGa	aAa	13	13	AY.117	0.001099
N	385	R385K	aGa	aAa	13	13	AY.16	0.004935
N	385	R385K	aGa	aAa	13	13	AY.41	0.003821
N	385	R385K	aGa	aAa	13	13	AY.58	0.011797
N	385	R385K	aGa	aAa	12	12	AY.37	0.003793
N	385	R385K	aGa	aAa	12	12	AY.47	0.000373
N	385	R385K	aGa	aAa	12	12	AY.62	0.005229
N	385	R385K	aGa	aAa	12	12	AY.85	0.005126
N	385	R385K	aGa	aAa	11	11	AY.21	0.020873
N	385	R385K	aGa	aAa	11	11	AY.45	0.001339
N	385	R385K	aGa	aAa	11	11	AY.68	0.003011
N	385	R385K	aGa	aAa	10	10	AY.61	0.001048
N	385	R385K	aGa	aAa	10	10	AY.86	0.008299
N	385	R385K	aGa	aAa	10	10	B.1.617.1	0.00129
N	385	R385K	aGa	aAa	9	9	AY.4	0.000014
N	385	R385K	aGa	aAa	9	9	AY.42	0.000362
N	385	R385K	aGa	aAa	9	9	B.1.497	0.002833
N	385	R385K	aGa	aAa	9	9	P.1	0.000142
N	385	R385K	aGa	aAa	8	8	AY.33	0.000534
N	385	R385K	aGa	aAa	8	8	B	0.001022
N	385	R385K	aGa	aAa	7	7	AY.103	0.000043
N	385	R385K	aGa	aAa	7	7	AY.24	0.003017
N	385	R385K	aGa	aAa	7	7	AY.25	0.000042
N	385	R385K	aGa	aAa	7	7	AY.39.1	0.000277
N	385	R385K	aGa	aAa	7	7	AY.48	0.003256
N	385	R385K	aGa	aAa	7	7	AY.52	0.0057
N	385	R385K	aGa	aAa	7	7	AY.53	0.002013
N	385	R385K	aGa	aAa	7	7	AY.64	0.004167
N	385	R385K	aGa	aAa	7	7	B.1.160.30	0.020833
N	385	R385K	aGa	aAa	7	7	B.1.429	0.000165
N	385	R385K	aGa	aAa	6	6	AY.49	0.019169
N	385	R385K	aGa	aAa	6	6	AY.51	0.005455
N	385	R385K	aGa	aAa	6	6	AY.79	0.007264
N	385	R385K	aGa	aAa	6	6	AY.9	0.000406
N	385	R385K	aGa	aAa	5	5	AY.100	0.00023
N	385	R385K	aGa	aAa	5	5	AY.121	0.000677
N	385	R385K	aGa	aAa	5	5	AY.19	0.005701
N	385	R385K	aGa	aAa	5	5	AY.46	0.00052
N	385	R385K	aGa	aAa	5	5	B.1.1	0.000091
N	385	R385K	aGa	aAa	4	4	AY.102	0.000106
N	385	R385K	aGa	aAa	4	4	AY.3	0.00004
N	385	R385K	aGa	aAa	4	4	AY.5.4	0.001107
N	385	R385K	aGa	aAa	4	4	AY.70	0.000834
N	385	R385K	aGa	aAa	4	4	AY.77	0.00451
N	385	R385K	aGa	aAa	4	4	AY.78	0.006163
N	385	R385K	aGa	aAa	4	4	B.1.160.15	0.019802
N	385	R385K	aGa	aAa	4	4	B.1.596	0.000349
N	385	R385K	aGa	aAa	3	3	AY.104	0.005952
N	385	R385K	aGa	aAa	3	3	AY.106	0.001005
N	385	R385K	aGa	aAa	3	3	AY.118	0.000188
N	385	R385K	aGa	aAa	3	3	AY.12	0.000948
N	385	R385K	aGa	aAa	3	3	AY.32	0.001597
N	385	R385K	aGa	aAa	3	3	AY.55	0.002752
N	385	R385K	aGa	aAa	3	3	AY.73	0.001996
N	385	R385K	aGa	aAa	3	3	AY.88	0.002653
N	385	R385K	aGa	aAa	3	3	B.1.1.519	0.000119
N	385	R385K	aGa	aAa	3	3	B.1.221	0.000213
N	385	R385K	aGa	aAa	3	3	P.1.1	0.000953
N	385	R385K	aGa	aAa	2	2	AY.101	0.000981
N	385	R385K	aGa	aAa	2	2	AY.105	0.001286
N	385	R385K	aGa	aAa	2	2	AY.109	0.001479
N	385	R385K	aGa	aAa	2	2	AY.110	0.000225
N	385	R385K	aGa	aAa	2	2	AY.114	0.000462
N	385	R385K	aGa	aAa	2	2	AY.116	0.000574
N	385	R385K	aGa	aAa	2	2	AY.23	0.000139
N	385	R385K	aGa	aAa	2	2	AY.71	0.00095
N	385	R385K	aGa	aAa	2	2	AY.87	0.001665
N	385	R385K	aGa	aAa	2	2	B.1.160.25	0.022222
N	385	R385K	aGa	aAa	2	2	B.1.177.43	0.002954
N	385	R385K	aGa	aAa	2	2	B.1.222	0.003384
N	385	R385K	aGa	aAa	2	2	B.1.258	0.000133
N	385	R385K	aGa	aAa	2	2	B.1.258.11	0.000793
N	385	R385K	aGa	aAa	2	2	B.1.39	0.007812
N	385	R385K	aGa	aAa	1	1	A	0.000387
N	385	R385K	aGa	aAa	1	1	AH.3	0.003802
N	385	R385K	aGa	aAa	1	1	AY.1	0.000396
N	385	R385K	aGa	aAa	1	1	AY.10	0.00053
N	385	R385K	aGa	aAa	1	1	AY.113	0.000142
N	385	R385K	aGa	aAa	1	1	AY.120.2	0.001285
N	385	R385K	aGa	aAa	1	1	AY.14	0.000088
N	385	R385K	aGa	aAa	1	1	AY.20	0.000039
N	385	R385K	aGa	aAa	1	1	AY.27	0.000065
N	385	R385K	aGa	aAa	1	1	AY.29	0.000016
N	385	R385K	aGa	aAa	1	1	AY.38	0.000499
N	385	R385K	aGa	aAa	1	1	AY.46.2	0.000635
N	385	R385K	aGa	aAa	1	1	AY.46.4	0.000165
N	385	R385K	aGa	aAa	1	1	AY.50	0.000799
N	385	R385K	aGa	aAa	1	1	AY.60	0.000938
N	385	R385K	aGa	aAa	1	1	AY.63	0.000387
N	385	R385K	aGa	aAa	1	1	AY.69	0.000187
N	385	R385K	aGa	aAa	1	1	AY.80	0.001129
N	385	R385K	aGa	aAa	1	1	AY.83	0.001724
N	385	R385K	aGa	aAa	1	1	AY.84	0.000437
N	385	R385K	aGa	aAa	1	1	AY.91	0.00073
N	385	R385K	aGa	aAa	1	1	AY.92	0.000287
N	385	R385K	aGa	aAa	1	1	AY.99.1	0.001553
N	385	R385K	aGa	aAa	1	1	B.1.1.10	0.001115
N	385	R385K	aGa	aAa	1	1	B.1.1.228	0.003049
N	385	R385K	aGA	aAG	1	1	B.1.1.27	0.00565
N	385	R385K	aGa	aAa	1	1	B.1.1.39	0.00051
N	385	R385K	aGa	aAa	1	1	B.1.1.442	0.018519
N	385	R385K	aGa	aAa	1	1	B.1.160.26	0.002421
N	385	R385K	aGa	aAa	1	1	B.1.160.33	0.004425
N	385	R385K	aGa	aAa	1	1	B.1.160.8	0.001289
N	385	R385K	aGa	aAa	1	1	B.1.177	0.000013
N	385	R385K	aGa	aAa	1	1	B.1.177.26	0.006993
N	385	R385K	aGa	aAa	1	1	B.1.177.57	0.000281
N	385	R385K	aGa	aAa	1	1	B.1.177.7	0.000165
N	385	R385K	aGa	aAa	1	1	B.1.177.73	0.000566
N	385	R385K	aGa	aAa	1	1	B.1.177.8	0.000752
N	385	R385K	aGa	aAa	1	1	B.1.214.2	0.0006
N	385	R385K	aGa	aAa	1	1	B.1.260	0.003344
N	385	R385K	aGa	aAa	1	1	B.1.36.29	0.000517
N	385	R385K	aGa	aAa	1	1	B.1.473	0.019231
N	385	R385K	aGa	aAa	1	1	B.1.509	0.000866
N	385	R385K	aGa	aAa	1	1	B.1.576	0.000907
N	385	R385K	aGa	aAa	1	1	B.1.595	0.000261
N	385	R385K	aGa	aAa	1	1	B.4.7	0.010101
N	385	R385K	aGa	aAa	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.