CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 32 | R32H | nonsyn | cGc | cAc | 3825 | 3825 | 1 | 28367-28369 |
Details of the mutation R32H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 32 | R32H | cGc | cAc | 3825 | 3825 | All | 0.000732 |
N | 32 | R32H | cGc | cAc | 1231 | 1231 | B.1.422 | 1 |
N | 32 | R32H | cGc | cAc | 401 | 401 | B.1.221 | 0.028484 |
N | 32 | R32H | cGc | cAc | 262 | 262 | AY.61 | 0.027452 |
N | 32 | R32H | cGc | cAc | 236 | 236 | B.1.617.2 | 0.000889 |
N | 32 | R32H | cGc | cAc | 219 | 219 | AY.44 | 0.001333 |
N | 32 | R32H | cGc | cAc | 197 | 197 | AY.4 | 0.000307 |
N | 32 | R32H | cGc | cAc | 176 | 176 | B.1.1.157 | 0.160731 |
N | 32 | R32H | cGc | cAc | 139 | 139 | B.1.1.7 | 0.000124 |
N | 32 | R32H | cGc | cAc | 87 | 87 | B.1.177.57 | 0.024445 |
N | 32 | R32H | cGc | cAc | 82 | 82 | AZ.1 | 0.071119 |
N | 32 | R32H | cGc | cAc | 73 | 73 | AY.103 | 0.000453 |
N | 32 | R32H | cGc | cAc | 69 | 69 | AY.14 | 0.006073 |
N | 32 | R32H | cGc | cAc | 48 | 48 | B.1 | 0.00044 |
N | 32 | R32H | cGc | cAc | 45 | 45 | B.1.305 | 0.096774 |
N | 32 | R32H | cGc | cAc | 29 | 29 | AY.5 | 0.000599 |
N | 32 | R32H | cGc | cAc | 27 | 27 | B.1.2 | 0.000238 |
N | 32 | R32H | cGc | cAc | 27 | 27 | B.1.429 | 0.000635 |
N | 32 | R32H | cGc | cAc | 27 | 27 | B.1.526 | 0.000635 |
N | 32 | R32H | cGc | cAc | 20 | 20 | AY.75.1 | 0.003606 |
N | 32 | R32H | cGc | cAc | 19 | 19 | AY.25 | 0.000114 |
N | 32 | R32H | cGc | cAc | 19 | 19 | B.1.36.36 | 0.011439 |
N | 32 | R32H | cGc | cAc | 19 | 19 | B.1.617.1 | 0.00245 |
N | 32 | R32H | cGc | cAc | 18 | 18 | B.1.1.63 | 0.006944 |
N | 32 | R32H | cGc | cAc | 16 | 16 | AY.4.4 | 0.006547 |
N | 32 | R32H | cGc | cAc | 15 | 15 | AY.20 | 0.000583 |
N | 32 | R32H | cGc | cAc | 15 | 15 | B.1.1 | 0.000272 |
N | 32 | R32H | cGc | cAc | 13 | 13 | AY.3 | 0.000129 |
N | 32 | R32H | cGc | cAc | 12 | 12 | AY.47 | 0.000373 |
N | 32 | R32H | cGc | cAc | 11 | 11 | AY.102 | 0.000292 |
N | 32 | R32H | cGc | cAc | 11 | 11 | P.1 | 0.000173 |
N | 32 | R32H | cGc | cAc | 10 | 10 | AY.29 | 0.000158 |
N | 32 | R32H | cGc | cAc | 10 | 10 | B.1.128 | 0.006353 |
N | 32 | R32H | cGc | cAc | 10 | 10 | B.1.351 | 0.000297 |
N | 32 | R32H | cGc | cAc | 8 | 8 | B.1.1.50 | 0.005431 |
N | 32 | R32H | cGc | cAc | 8 | 8 | B.1.427 | 0.000404 |
N | 32 | R32H | cGc | cAc | 7 | 7 | AY.26 | 0.000198 |
N | 32 | R32H | cGc | cAc | 7 | 7 | B.1.177 | 0.000092 |
N | 32 | R32H | cGc | cAc | 7 | 7 | B.1.366 | 0.034146 |
N | 32 | R32H | cGc | cAc | 6 | 6 | AY.120 | 0.000223 |
N | 32 | R32H | cGc | cAc | 6 | 6 | AY.43 | 0.000027 |
N | 32 | R32H | cGc | cAc | 6 | 6 | AY.91 | 0.004383 |
N | 32 | R32H | cGc | cAc | 6 | 6 | B.1.1.519 | 0.000238 |
N | 32 | R32H | cGc | cAc | 6 | 6 | B.1.459 | 0.02449 |
N | 32 | R32H | cGc | cAc | 5 | 5 | AY.100 | 0.00023 |
N | 32 | R32H | cGc | cAc | 5 | 5 | AY.4.2 | 0.000108 |
N | 32 | R32H | cGc | cAc | 5 | 5 | AY.71 | 0.002375 |
N | 32 | R32H | cGc | cAc | 5 | 5 | B.1.448 | 0.013123 |
N | 32 | R32H | cGc | cAc | 5 | 5 | B.6 | 0.00455 |
N | 32 | R32H | cGc | cAc | 4 | 4 | AY.27 | 0.000259 |
N | 32 | R32H | cGc | cAc | 4 | 4 | AY.42 | 0.000161 |
N | 32 | R32H | cGc | cAc | 4 | 4 | AY.86 | 0.00332 |
N | 32 | R32H | cGc | cAc | 4 | 4 | C.11 | 0.042553 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.110 | 0.000338 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.113 | 0.000427 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.24 | 0.001293 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.39 | 0.000074 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.54 | 0.000286 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.62 | 0.001307 |
N | 32 | R32H | cGc | cAc | 3 | 3 | AY.87 | 0.002498 |
N | 32 | R32H | cGc | cAc | 3 | 3 | B.1.1.348 | 0.002389 |
N | 32 | R32H | cGc | cAc | 3 | 3 | B.1.177.60 | 0.000655 |
N | 32 | R32H | cGc | cAc | 3 | 3 | B.1.258 | 0.0002 |
N | 32 | R32H | cGc | cAc | 3 | 3 | B.1.619.1 | 0.001924 |
N | 32 | R32H | cGc | cAc | 3 | 3 | R.1 | 0.00027 |
N | 32 | R32H | cGc | cAc | 2 | 2 | A.23.1 | 0.001408 |
N | 32 | R32H | cGc | cAc | 2 | 2 | AY.13 | 0.000322 |
N | 32 | R32H | cGc | cAc | 2 | 2 | AY.23 | 0.000139 |
N | 32 | R32H | cGc | cAc | 2 | 2 | AY.55 | 0.001835 |
N | 32 | R32H | cGc | cAc | 2 | 2 | AY.59 | 0.001059 |
N | 32 | R32H | cGc | cAc | 2 | 2 | AY.65 | 0.001066 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.1.318 | 0.000604 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.243 | 0.000139 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.596 | 0.000174 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.609 | 0.000959 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.619 | 0.001742 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.621 | 0.000177 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.1.93 | 0.001867 |
N | 32 | R32H | cGc | cAc | 2 | 2 | B.35 | 0.015625 |
N | 32 | R32H | cGc | cAc | 2 | 2 | P.1.14 | 0.000096 |
N | 32 | R32H | cGc | cAc | 2 | 2 | P.1.15 | 0.000465 |
N | 32 | R32H | cGc | cAc | 1 | 1 | A.2.4 | 0.003367 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AP.1 | 0.001502 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.10 | 0.00053 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.117 | 0.000085 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.118 | 0.000063 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.119 | 0.000035 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.121 | 0.000135 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.16 | 0.00038 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.16.1 | 0.00047 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.19 | 0.00114 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.32 | 0.000532 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.34.1 | 0.00051 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.36 | 0.000148 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.39.1 | 0.00004 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.41 | 0.000294 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.46 | 0.000104 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.46.6 | 0.000072 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.57 | 0.000656 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.64 | 0.000595 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.69 | 0.000187 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.75 | 0.000056 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.8 | 0.000606 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.95 | 0.000761 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.98 | 0.000079 |
N | 32 | R32H | cGc | cAc | 1 | 1 | AY.98.1 | 0.000048 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B | 0.000128 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.176 | 0.000439 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.189 | 0.001513 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.28 | 0.000311 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.311 | 0.000358 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.362 | 0.005618 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.37 | 0.000193 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.434 | 0.000349 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.1.440 | 0.011765 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.131 | 0.008772 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.160.10 | 0.008065 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.177.4 | 0.000211 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.177.7 | 0.000165 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.177.75 | 0.001041 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.234 | 0.000132 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.240 | 0.000216 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.36.1 | 0.00114 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.487 | 0.019608 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.497 | 0.000315 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.509 | 0.000866 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.525 | 0.000113 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.555 | 0.022222 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.564 | 0.000426 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.595 | 0.000261 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.623 | 0.000536 |
N | 32 | R32H | cGc | cAc | 1 | 1 | B.1.637 | 0.000073 |
N | 32 | R32H | cGc | cAc | 1 | 1 | N.5 | 0.001767 |
N | 32 | R32H | cGc | cAc | 1 | 1 | P.1.10 | 0.000269 |
N | 32 | R32H | cGc | cAc | 1 | 1 | P.1.4 | 0.000977 |
N | 32 | R32H | cGc | cAc | 1 | 1 | P.2 | 0.000187 |
N | 32 | R32H | cGc | cAc | 1 | 1 | U.1 | 0.012821 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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