CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 203 | R203I | nonsyn | aGG | aTT | 1679 | 1092 | 0.650387 | 28880-28882 | |
N | 203 | R203I | nonsyn | aGG | aTA | 1679 | 413 | 0.24598 | 28880-28882 | |
N | 203 | R203I | nonsyn | aGG | aTC | 1679 | 174 | 0.103633 | 28880-28882 |
Details of the mutation R203I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 203 | R203I | aGG | aTT | 1092 | 1679 | All | 0.000209 |
N | 203 | R203I | aGG | aTA | 413 | 1679 | All | 0.000079 |
N | 203 | R203I | aGG | aTC | 174 | 1679 | All | 0.000033 |
N | 203 | R203I | aGG | aTT | 247 | 253 | AY.98.1 | 0.011962 |
N | 203 | R203I | aGG | aTA | 6 | 253 | AY.98.1 | 0.000291 |
N | 203 | R203I | aGG | aTC | 131 | 206 | AY.44 | 0.000797 |
N | 203 | R203I | aGG | aTT | 61 | 206 | AY.44 | 0.000371 |
N | 203 | R203I | aGG | aTA | 14 | 206 | AY.44 | 0.000085 |
N | 203 | R203I | aGG | aTT | 116 | 149 | B.1.617.2 | 0.000437 |
N | 203 | R203I | aGG | aTA | 27 | 149 | B.1.617.2 | 0.000102 |
N | 203 | R203I | aGG | aTC | 6 | 149 | B.1.617.2 | 0.000023 |
N | 203 | R203I | aGG | aTT | 105 | 130 | AY.43 | 0.000465 |
N | 203 | R203I | aGG | aTA | 24 | 130 | AY.43 | 0.000106 |
N | 203 | R203I | aGG | aTC | 1 | 130 | AY.43 | 0.000004 |
N | 203 | R203I | aGG | aTT | 94 | 115 | AY.4 | 0.000146 |
N | 203 | R203I | aGG | aTA | 13 | 115 | AY.4 | 0.00002 |
N | 203 | R203I | aGG | aTC | 8 | 115 | AY.4 | 0.000012 |
N | 203 | R203I | aGG | aTA | 94 | 95 | AY.5.3 | 0.031714 |
N | 203 | R203I | aGG | aTT | 1 | 95 | AY.5.3 | 0.000337 |
N | 203 | R203I | aGG | aTT | 79 | 79 | AY.45 | 0.009613 |
N | 203 | R203I | aGG | aTT | 49 | 55 | AY.3 | 0.000487 |
N | 203 | R203I | aGG | aTA | 4 | 55 | AY.3 | 0.00004 |
N | 203 | R203I | aGG | aTC | 2 | 55 | AY.3 | 0.00002 |
N | 203 | R203I | aGG | aTT | 30 | 50 | AY.25 | 0.00018 |
N | 203 | R203I | aGG | aTA | 18 | 50 | AY.25 | 0.000108 |
N | 203 | R203I | aGG | aTC | 2 | 50 | AY.25 | 0.000012 |
N | 203 | R203I | aGG | aTA | 46 | 47 | B.1 | 0.000421 |
N | 203 | R203I | aGG | aTT | 1 | 47 | B.1 | 0.000009 |
N | 203 | R203I | aGG | aTT | 26 | 40 | AY.103 | 0.000161 |
N | 203 | R203I | aGG | aTC | 10 | 40 | AY.103 | 0.000062 |
N | 203 | R203I | aGG | aTA | 4 | 40 | AY.103 | 0.000025 |
N | 203 | R203I | aGG | aTT | 37 | 37 | AY.119 | 0.001306 |
N | 203 | R203I | aGG | aTT | 26 | 29 | AY.102 | 0.000689 |
N | 203 | R203I | aGG | aTA | 2 | 29 | AY.102 | 0.000053 |
N | 203 | R203I | aGG | aTC | 1 | 29 | AY.102 | 0.000027 |
N | 203 | R203I | aGG | aTA | 26 | 26 | B.1.1.7 | 0.000023 |
N | 203 | R203I | aGG | aTT | 21 | 23 | AY.20 | 0.000816 |
N | 203 | R203I | aGG | aTA | 1 | 23 | AY.20 | 0.000039 |
N | 203 | R203I | aGG | aTC | 1 | 23 | AY.20 | 0.000039 |
N | 203 | R203I | aGG | aTT | 19 | 21 | AY.47 | 0.000591 |
N | 203 | R203I | aGG | aTA | 2 | 21 | AY.47 | 0.000062 |
N | 203 | R203I | aGG | aTA | 18 | 20 | AY.4.2 | 0.00039 |
N | 203 | R203I | aGG | aTT | 2 | 20 | AY.4.2 | 0.000043 |
N | 203 | R203I | aGG | aTC | 11 | 19 | AY.29 | 0.000174 |
N | 203 | R203I | aGG | aTT | 7 | 19 | AY.29 | 0.00011 |
N | 203 | R203I | aGG | aTA | 1 | 19 | AY.29 | 0.000016 |
N | 203 | R203I | aGG | aTT | 16 | 17 | AY.9.2 | 0.000588 |
N | 203 | R203I | aGG | aTA | 1 | 17 | AY.9.2 | 0.000037 |
N | 203 | R203I | aGG | aTT | 14 | 15 | AY.100 | 0.000644 |
N | 203 | R203I | aGG | aTC | 1 | 15 | AY.100 | 0.000046 |
N | 203 | R203I | aGG | aTT | 15 | 15 | AY.99.2 | 0.001382 |
N | 203 | R203I | aGG | aTA | 7 | 11 | AY.23 | 0.000488 |
N | 203 | R203I | aGG | aTT | 4 | 11 | AY.23 | 0.000279 |
N | 203 | R203I | aGG | aTT | 10 | 10 | AY.14 | 0.00088 |
N | 203 | R203I | aGG | aTT | 9 | 9 | AY.46 | 0.000937 |
N | 203 | R203I | aGG | aTA | 4 | 8 | AY.26 | 0.000113 |
N | 203 | R203I | aGG | aTT | 4 | 8 | AY.26 | 0.000113 |
N | 203 | R203I | aGG | aTT | 8 | 8 | AY.33 | 0.000534 |
N | 203 | R203I | aGG | aTT | 5 | 8 | AY.75.1 | 0.000902 |
N | 203 | R203I | aGG | aTA | 3 | 8 | AY.75.1 | 0.000541 |
N | 203 | R203I | aGG | aTA | 8 | 8 | P.1 | 0.000126 |
N | 203 | R203I | aGG | aTT | 6 | 7 | AY.5.4 | 0.00166 |
N | 203 | R203I | aGG | aTA | 1 | 7 | AY.5.4 | 0.000277 |
N | 203 | R203I | aGG | aTT | 5 | 6 | AY.113 | 0.000712 |
N | 203 | R203I | aGG | aTA | 1 | 6 | AY.113 | 0.000142 |
N | 203 | R203I | aGG | aTA | 5 | 6 | AY.27 | 0.000324 |
N | 203 | R203I | aGG | aTT | 1 | 6 | AY.27 | 0.000065 |
N | 203 | R203I | aGG | aTA | 5 | 6 | B | 0.000639 |
N | 203 | R203I | aGG | aTT | 1 | 6 | B | 0.000128 |
N | 203 | R203I | aGG | aTA | 3 | 5 | AY.120 | 0.000112 |
N | 203 | R203I | aGG | aTT | 2 | 5 | AY.120 | 0.000074 |
N | 203 | R203I | aGG | aTA | 3 | 5 | AY.5 | 0.000062 |
N | 203 | R203I | aGG | aTT | 2 | 5 | AY.5 | 0.000041 |
N | 203 | R203I | aGG | aTT | 5 | 5 | AY.60 | 0.00469 |
N | 203 | R203I | aGG | aTT | 5 | 5 | AY.78 | 0.007704 |
N | 203 | R203I | aGG | aTA | 5 | 5 | AY.92 | 0.001436 |
N | 203 | R203I | aGG | aTT | 4 | 4 | AY.19 | 0.004561 |
N | 203 | R203I | aGG | aTT | 4 | 4 | AY.36 | 0.000593 |
N | 203 | R203I | aGG | aTT | 4 | 4 | AY.39 | 0.000099 |
N | 203 | R203I | aGG | aTA | 4 | 4 | AY.39.1 | 0.000158 |
N | 203 | R203I | aGG | aTA | 3 | 4 | AY.42 | 0.000121 |
N | 203 | R203I | aGG | aTT | 1 | 4 | AY.42 | 0.00004 |
N | 203 | R203I | aGG | aTA | 4 | 4 | AY.52 | 0.003257 |
N | 203 | R203I | aGG | aTT | 4 | 4 | AY.61 | 0.000419 |
N | 203 | R203I | aGG | aTA | 2 | 3 | AY.30 | 0.000791 |
N | 203 | R203I | aGG | aTT | 1 | 3 | AY.30 | 0.000396 |
N | 203 | R203I | aGG | aTT | 3 | 3 | AY.46.6 | 0.000217 |
N | 203 | R203I | aGG | aTT | 3 | 3 | AY.54 | 0.000286 |
N | 203 | R203I | aGG | aTA | 2 | 3 | AY.68 | 0.000547 |
N | 203 | R203I | aGG | aTT | 1 | 3 | AY.68 | 0.000274 |
N | 203 | R203I | aGG | aTT | 3 | 3 | AY.73 | 0.001996 |
N | 203 | R203I | aGG | aTA | 2 | 3 | AY.80 | 0.002257 |
N | 203 | R203I | aGG | aTT | 1 | 3 | AY.80 | 0.001129 |
N | 203 | R203I | aGG | aTA | 3 | 3 | AY.9.1 | 0.000251 |
N | 203 | R203I | aGG | aTA | 3 | 3 | B.1.1 | 0.000054 |
N | 203 | R203I | aGG | aTA | 3 | 3 | B.1.375 | 0.002459 |
N | 203 | R203I | aGG | aTA | 3 | 3 | B.1.576 | 0.00272 |
N | 203 | R203I | aGG | aTA | 2 | 2 | AY.110 | 0.000225 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.114 | 0.000462 |
N | 203 | R203I | aGG | aTA | 2 | 2 | AY.116.1 | 0.000623 |
N | 203 | R203I | aGG | aTA | 1 | 2 | AY.117 | 0.000085 |
N | 203 | R203I | aGG | aTT | 1 | 2 | AY.117 | 0.000085 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.121 | 0.000271 |
N | 203 | R203I | aGG | aTA | 1 | 2 | AY.13 | 0.000161 |
N | 203 | R203I | aGG | aTT | 1 | 2 | AY.13 | 0.000161 |
N | 203 | R203I | aGG | aTA | 2 | 2 | AY.34 | 0.000194 |
N | 203 | R203I | aGG | aTA | 2 | 2 | AY.4.2.1 | 0.000298 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.46.3 | 0.001867 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.6 | 0.000082 |
N | 203 | R203I | aGG | aTT | 1 | 2 | AY.75 | 0.000056 |
N | 203 | R203I | aGG | aTA | 1 | 2 | AY.75 | 0.000056 |
N | 203 | R203I | aGG | aTA | 2 | 2 | AY.95 | 0.001522 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.98 | 0.000158 |
N | 203 | R203I | aGG | aTT | 2 | 2 | AY.99 | 0.002099 |
N | 203 | R203I | aGG | aTA | 1 | 2 | B.1.617.1 | 0.000129 |
N | 203 | R203I | aGG | aTT | 1 | 2 | B.1.617.1 | 0.000129 |
N | 203 | R203I | aGG | aTA | 2 | 2 | C.37.1 | 0.005236 |
N | 203 | R203I | aGG | aTA | 2 | 2 | P.1.17 | 0.000324 |
N | 203 | R203I | aGG | aTA | 1 | 1 | A | 0.000387 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.106 | 0.000335 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.108 | 0.001103 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.11 | 0.001339 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.118 | 0.000063 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.16 | 0.00038 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.16.1 | 0.00047 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.23.1 | 0.000417 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.3.1 | 0.000085 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.32 | 0.000532 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.34.1 | 0.00051 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.4.5 | 0.000107 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.51 | 0.000909 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.55 | 0.000917 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.58 | 0.000907 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.65 | 0.000533 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.71 | 0.000475 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AY.77 | 0.001127 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.87 | 0.000833 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.88 | 0.000884 |
N | 203 | R203I | aGG | aTT | 1 | 1 | AY.99.1 | 0.001553 |
N | 203 | R203I | aGG | aTA | 1 | 1 | AZ.2 | 0.000821 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.1.413 | 0.006897 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.131 | 0.008772 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.2 | 0.000009 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.301 | 0.005917 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.432 | 0.011236 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.433 | 0.003195 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.581 | 0.009434 |
N | 203 | R203I | aGG | aTA | 1 | 1 | B.1.623 | 0.000536 |
N | 203 | R203I | aGG | aTT | 1 | 1 | C.36.3 | 0.000567 |
N | 203 | R203I | aGG | aTA | 1 | 1 | C.36.3.1 | 0.002717 |
N | 203 | R203I | aGG | aTA | 1 | 1 | C.37 | 0.000116 |
N | 203 | R203I | aGG | aTA | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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