CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 6 | P6L | nonsyn | cCc | cTc | 5735 | 5735 | 1 | 28289-28291 |
Details of the mutation P6L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 6 | P6L | cCc | cTc | 5735 | 5735 | All | 0.001097 |
N | 6 | P6L | cCc | cTc | 1812 | 1812 | B.1.438.1 | 0.194358 |
N | 6 | P6L | cCc | cTc | 753 | 753 | AY.103 | 0.004675 |
N | 6 | P6L | cCc | cTc | 382 | 382 | B.1.617.2 | 0.001438 |
N | 6 | P6L | cCc | cTc | 375 | 375 | B.1.1.7 | 0.000336 |
N | 6 | P6L | cCc | cTc | 235 | 235 | AY.4 | 0.000366 |
N | 6 | P6L | cCc | cTc | 210 | 210 | B.1.1.159 | 0.981308 |
N | 6 | P6L | cCc | cTc | 177 | 177 | AY.44 | 0.001077 |
N | 6 | P6L | cCc | cTc | 155 | 155 | AY.36 | 0.022973 |
N | 6 | P6L | cCc | cTc | 146 | 146 | B.1.2 | 0.001286 |
N | 6 | P6L | cCc | cTc | 131 | 131 | B.1 | 0.0012 |
N | 6 | P6L | cCc | cTc | 80 | 80 | AY.102 | 0.002121 |
N | 6 | P6L | cCc | cTc | 64 | 64 | AY.121 | 0.00866 |
N | 6 | P6L | cCc | cTc | 60 | 60 | B.1.1 | 0.001088 |
N | 6 | P6L | cCc | cTc | 57 | 57 | P.1 | 0.000898 |
N | 6 | P6L | cCc | cTc | 56 | 56 | AY.26 | 0.001585 |
N | 6 | P6L | cCc | cTc | 52 | 52 | AY.25 | 0.000313 |
N | 6 | P6L | cCc | cTc | 47 | 47 | B.1.243 | 0.00327 |
N | 6 | P6L | cCc | cTc | 41 | 41 | AY.43 | 0.000182 |
N | 6 | P6L | cCc | cTc | 32 | 32 | AY.3 | 0.000318 |
N | 6 | P6L | cCc | cTc | 32 | 32 | B.1.351 | 0.000951 |
N | 6 | P6L | cCc | cTc | 31 | 31 | AY.23 | 0.002162 |
N | 6 | P6L | cCc | cTc | 29 | 29 | R.1 | 0.00261 |
N | 6 | P6L | cCc | cTc | 28 | 28 | AY.33 | 0.00187 |
N | 6 | P6L | cCc | cTc | 26 | 26 | AY.105 | 0.01672 |
N | 6 | P6L | cCc | cTc | 23 | 23 | B.1.177 | 0.000303 |
N | 6 | P6L | cCc | cTc | 20 | 20 | AY.5 | 0.000413 |
N | 6 | P6L | cCc | cTc | 18 | 18 | AY.29 | 0.000284 |
N | 6 | P6L | cCc | cTc | 18 | 18 | B.1.1.519 | 0.000715 |
N | 6 | P6L | cCc | cTc | 17 | 17 | B.1.1.222 | 0.003468 |
N | 6 | P6L | cCc | cTc | 16 | 16 | B.1.1.424 | 0.727273 |
N | 6 | P6L | cCc | cTc | 16 | 16 | B.1.369 | 0.004564 |
N | 6 | P6L | cCc | cTc | 16 | 16 | B.1.517 | 0.006832 |
N | 6 | P6L | cCc | cTc | 15 | 15 | B.1.111 | 0.017626 |
N | 6 | P6L | cCc | cTc | 14 | 14 | AY.20 | 0.000544 |
N | 6 | P6L | cCc | cTc | 14 | 14 | B.1.1.397 | 0.031532 |
N | 6 | P6L | cCc | cTc | 13 | 13 | AY.46 | 0.001353 |
N | 6 | P6L | cCc | cTc | 13 | 13 | B.1.234 | 0.001715 |
N | 6 | P6L | cCc | cTc | 13 | 13 | B.1.36.17 | 0.006423 |
N | 6 | P6L | cCc | cTc | 13 | 13 | B.1.577 | 0.008935 |
N | 6 | P6L | cCc | cTc | 12 | 12 | AY.9.1 | 0.001005 |
N | 6 | P6L | cCc | cTc | 12 | 12 | B.1.1.406 | 0.077922 |
N | 6 | P6L | cCc | cTc | 11 | 11 | AY.117 | 0.00093 |
N | 6 | P6L | cCc | cTc | 11 | 11 | P.1.16 | 0.004115 |
N | 6 | P6L | cCc | cTc | 10 | 10 | B.1.596 | 0.000871 |
N | 6 | P6L | cCc | cTc | 9 | 9 | AY.39.2 | 0.013867 |
N | 6 | P6L | cCc | cTc | 9 | 9 | AY.47 | 0.00028 |
N | 6 | P6L | cCc | cTc | 9 | 9 | B.1.258 | 0.000599 |
N | 6 | P6L | cCc | cTc | 8 | 8 | AY.39 | 0.000198 |
N | 6 | P6L | cCc | cTc | 8 | 8 | AY.55 | 0.007339 |
N | 6 | P6L | cCc | cTc | 8 | 8 | AY.64 | 0.004762 |
N | 6 | P6L | cCc | cTc | 8 | 8 | AY.74 | 0.000925 |
N | 6 | P6L | cCc | cTc | 8 | 8 | B.1.177.32 | 0.010796 |
N | 6 | P6L | cCc | cTc | 7 | 7 | AY.4.2 | 0.000152 |
N | 6 | P6L | cCc | cTc | 7 | 7 | B.1.617.1 | 0.000903 |
N | 6 | P6L | cCc | cTc | 7 | 7 | P.1.14 | 0.000335 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.100 | 0.000276 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.4.5 | 0.000645 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.46.6 | 0.000433 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.95 | 0.004566 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.98 | 0.000474 |
N | 6 | P6L | cCc | cTc | 6 | 6 | AY.98.1 | 0.000291 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.1.1.28 | 0.001867 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.1.221 | 0.000426 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.1.240 | 0.001293 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.1.241 | 0.00487 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.1.526 | 0.000141 |
N | 6 | P6L | cCc | cTc | 6 | 6 | B.6.6 | 0.005333 |
N | 6 | P6L | cCc | cTc | 5 | 5 | AY.118 | 0.000313 |
N | 6 | P6L | cCc | cTc | 5 | 5 | AY.15 | 0.011111 |
N | 6 | P6L | cCc | cTc | 5 | 5 | AY.61 | 0.000524 |
N | 6 | P6L | cCc | cTc | 5 | 5 | B.1.1.317 | 0.002058 |
N | 6 | P6L | cCc | cTc | 5 | 5 | B.1.160 | 0.000156 |
N | 6 | P6L | cCc | cTc | 5 | 5 | B.1.36 | 0.00073 |
N | 6 | P6L | cCc | cTc | 5 | 5 | B.1.429 | 0.000118 |
N | 6 | P6L | cCc | cTc | 4 | 4 | A.2.5 | 0.001996 |
N | 6 | P6L | cCc | cTc | 4 | 4 | AY.116.1 | 0.001246 |
N | 6 | P6L | cCc | cTc | 4 | 4 | AY.120 | 0.000149 |
N | 6 | P6L | cCc | cTc | 4 | 4 | AY.42 | 0.000161 |
N | 6 | P6L | cCc | cTc | 4 | 4 | AY.9.2 | 0.000147 |
N | 6 | P6L | cCc | cTc | 4 | 4 | AY.99.2 | 0.000369 |
N | 6 | P6L | cCc | cTc | 4 | 4 | B.1.1.33 | 0.001684 |
N | 6 | P6L | cCc | cTc | 4 | 4 | B.1.1.37 | 0.000771 |
N | 6 | P6L | cCc | cTc | 4 | 4 | B.1.1.50 | 0.002716 |
N | 6 | P6L | cCc | cTc | 4 | 4 | B.1.621 | 0.000354 |
N | 6 | P6L | cCc | cTc | 4 | 4 | B.1.623 | 0.002146 |
N | 6 | P6L | cCc | cTc | 4 | 4 | P.1.10 | 0.001078 |
N | 6 | P6L | cCc | cTc | 4 | 4 | P.1.17 | 0.000647 |
N | 6 | P6L | cCc | cTc | 3 | 3 | A | 0.001161 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.14 | 0.000264 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.27 | 0.000194 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.3.1 | 0.000256 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.35 | 0.000699 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.6 | 0.000123 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.67 | 0.001393 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.75 | 0.000168 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.84 | 0.001312 |
N | 6 | P6L | cCc | cTc | 3 | 3 | AY.9 | 0.000203 |
N | 6 | P6L | cCc | cTc | 3 | 3 | B | 0.000383 |
N | 6 | P6L | cCc | cTc | 3 | 3 | B.1.1.482 | 0.069767 |
N | 6 | P6L | cCc | cTc | 3 | 3 | B.1.177.81 | 0.000568 |
N | 6 | P6L | cCc | cTc | 3 | 3 | B.1.438 | 0.019608 |
N | 6 | P6L | cCc | cTc | 3 | 3 | B.1.609 | 0.001438 |
N | 6 | P6L | cCc | cTc | 3 | 3 | C.2 | 0.048387 |
N | 6 | P6L | cCc | cTc | 3 | 3 | P.1.7 | 0.000958 |
N | 6 | P6L | cCc | cTc | 2 | 2 | A.21 | 0.00554 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.113 | 0.000285 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.30 | 0.000791 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.45 | 0.000243 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.46.2 | 0.001271 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.5.4 | 0.000553 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.52 | 0.001629 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.54 | 0.000191 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.59 | 0.001059 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.66 | 0.002139 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.75.1 | 0.000361 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.82 | 0.002714 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.85 | 0.000854 |
N | 6 | P6L | cCc | cTc | 2 | 2 | AY.89 | 0.009804 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.1.220 | 0.003717 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.1.284 | 0.000215 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.1.356 | 0.017094 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.1.416 | 0.00181 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.110.3 | 0.001437 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.177.54 | 0.001213 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.177.87 | 0.001456 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.427 | 0.000101 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.507 | 0.022472 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.525 | 0.000226 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.557 | 0.1 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.597 | 0.009259 |
N | 6 | P6L | cCc | cTc | 2 | 2 | B.1.637 | 0.000146 |
N | 6 | P6L | cCc | cTc | 2 | 2 | L.2 | 0.022727 |
N | 6 | P6L | cCc | cTc | 2 | 2 | P.1.13 | 0.001797 |
N | 6 | P6L | cCc | cTc | 2 | 2 | P.2 | 0.000373 |
N | 6 | P6L | cCc | cTc | 1 | 1 | A.2.5.2 | 0.001572 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AE.8 | 0.000489 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.101 | 0.00049 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.110 | 0.000113 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.111 | 0.000183 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.114 | 0.000231 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.119 | 0.000035 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.12 | 0.000316 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.120.1 | 0.000321 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.120.2 | 0.001285 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.16.1 | 0.00047 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.23.1 | 0.000417 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.24 | 0.000431 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.34 | 0.000097 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.38 | 0.000499 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.4.2.1 | 0.000149 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.46.1 | 0.001027 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.46.4 | 0.000165 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.48 | 0.000465 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.49 | 0.003195 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.5.3 | 0.000337 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.53 | 0.000288 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.7.1 | 0.000113 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.86 | 0.00083 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.87 | 0.000833 |
N | 6 | P6L | cCc | cTc | 1 | 1 | AY.99.1 | 0.001553 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.1 | 0.000327 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.141 | 0.002012 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.176 | 0.000439 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.189 | 0.001513 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.216 | 0.00089 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.25 | 0.000569 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.302 | 0.002075 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.306 | 0.000438 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.389 | 0.006061 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.437 | 0.010417 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.1.525 | 0.005464 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.10 | 0.000878 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.12 | 0.000152 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.23 | 0.003236 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.41 | 0.0025 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.46 | 0.000918 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.74 | 0.015152 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.80 | 0.001912 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.177.9 | 0.001332 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.223 | 0.002778 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.236 | 0.002053 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.239 | 0.001221 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.258.17 | 0.000104 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.319 | 0.003049 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.351.2 | 0.000303 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.408 | 0.00369 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.459 | 0.004082 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.465 | 0.003802 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.466.2 | 0.000391 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.538 | 0.008065 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.561 | 0.000397 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.565 | 0.00081 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.580 | 0.004065 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.619 | 0.000871 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.1.621.1 | 0.000506 |
N | 6 | P6L | cCc | cTc | 1 | 1 | B.61 | 0.005747 |
N | 6 | P6L | cCc | cTc | 1 | 1 | C.37 | 0.000116 |
N | 6 | P6L | cCc | cTc | 1 | 1 | D.2 | 0.000075 |
N | 6 | P6L | cCc | cTc | 1 | 1 | N.3 | 0.005814 |
N | 6 | P6L | cCc | cTc | 1 | 1 | N.6 | 0.007092 |
N | 6 | P6L | cCc | cTc | 1 | 1 | N.9 | 0.005952 |
N | 6 | P6L | cCc | cTc | 1 | 1 | P.1.12 | 0.000484 |
N | 6 | P6L | cCc | cTc | 1 | 1 | P.1.15 | 0.000232 |
N | 6 | P6L | cCc | cTc | 1 | 1 | Q.1 | 0.000126 |
N | 6 | P6L | cCc | cTc | 1 | 1 | Z.1 | 0.00289 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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