CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 364 | P364L | nonsyn | cCa | cTa | 4426 | 4416 | 0.997741 | 29363-29365 | |
N | 364 | P364L | nonsyn | CCa | TTa | 4426 | 5 | 0.00112969 | 29363-29365 | |
N | 364 | P364L | nonsyn | cCA | cTC | 4426 | 4 | 0.000903751 | 29363-29365 | |
N | 364 | P364L | nonsyn | cCA | cTG | 4426 | 1 | 0.000225938 | 29363-29365 |
Details of the mutation P364L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 364 | P364L | cCa | cTa | 4416 | 4426 | All | 0.000845 |
N | 364 | P364L | CCa | TTa | 5 | 4426 | All | 0.000001 |
N | 364 | P364L | cCA | cTC | 4 | 4426 | All | 0.000001 |
N | 364 | P364L | cCA | cTG | 1 | 4426 | All | 0 |
N | 364 | P364L | cCa | cTa | 2367 | 2370 | B.1.2 | 0.020842 |
N | 364 | P364L | cCA | cTC | 1 | 2370 | B.1.2 | 0.000009 |
N | 364 | P364L | CCa | TTa | 1 | 2370 | B.1.2 | 0.000009 |
N | 364 | P364L | cCA | cTG | 1 | 2370 | B.1.2 | 0.000009 |
N | 364 | P364L | cCa | cTa | 380 | 381 | B.1.617.2 | 0.001431 |
N | 364 | P364L | CCa | TTa | 1 | 381 | B.1.617.2 | 0.000004 |
N | 364 | P364L | cCa | cTa | 262 | 263 | B.1.1.7 | 0.000235 |
N | 364 | P364L | cCA | cTC | 1 | 263 | B.1.1.7 | 0.000001 |
N | 364 | P364L | cCa | cTa | 170 | 170 | AY.102 | 0.004507 |
N | 364 | P364L | cCa | cTa | 162 | 162 | B.1.573 | 0.987805 |
N | 364 | P364L | cCa | cTa | 137 | 137 | AY.4 | 0.000213 |
N | 364 | P364L | cCa | cTa | 114 | 116 | B.1 | 0.001044 |
N | 364 | P364L | cCA | cTC | 1 | 116 | B.1 | 0.000009 |
N | 364 | P364L | CCa | TTa | 1 | 116 | B.1 | 0.000009 |
N | 364 | P364L | cCa | cTa | 60 | 60 | B.1.1 | 0.001088 |
N | 364 | P364L | cCa | cTa | 49 | 49 | AY.44 | 0.000298 |
N | 364 | P364L | cCa | cTa | 42 | 42 | AY.43 | 0.000186 |
N | 364 | P364L | cCa | cTa | 37 | 39 | B.1.160 | 0.001154 |
N | 364 | P364L | cCA | cTC | 1 | 39 | B.1.160 | 0.000031 |
N | 364 | P364L | CCa | TTa | 1 | 39 | B.1.160 | 0.000031 |
N | 364 | P364L | cCa | cTa | 39 | 39 | P.1 | 0.000614 |
N | 364 | P364L | cCa | cTa | 33 | 33 | P.1.14 | 0.001577 |
N | 364 | P364L | cCa | cTa | 30 | 30 | B.1.429 | 0.000706 |
N | 364 | P364L | cCa | cTa | 25 | 25 | AY.39 | 0.000618 |
N | 364 | P364L | cCa | cTa | 25 | 25 | AY.47 | 0.000778 |
N | 364 | P364L | cCa | cTa | 23 | 23 | AY.98.1 | 0.001114 |
N | 364 | P364L | cCa | cTa | 22 | 22 | AY.3 | 0.000219 |
N | 364 | P364L | cCa | cTa | 21 | 21 | B.1.596 | 0.00183 |
N | 364 | P364L | cCa | cTa | 18 | 18 | AY.103 | 0.000112 |
N | 364 | P364L | cCa | cTa | 17 | 17 | B.1.427 | 0.000858 |
N | 364 | P364L | cCa | cTa | 16 | 16 | AY.25 | 0.000096 |
N | 364 | P364L | cCa | cTa | 14 | 14 | B.1.1.416 | 0.01267 |
N | 364 | P364L | cCa | cTa | 13 | 13 | AY.4.2 | 0.000282 |
N | 364 | P364L | cCa | cTa | 11 | 11 | AY.26 | 0.000311 |
N | 364 | P364L | cCa | cTa | 11 | 11 | B.1.1.318 | 0.003319 |
N | 364 | P364L | cCa | cTa | 9 | 10 | AY.98 | 0.000711 |
N | 364 | P364L | CCa | TTa | 1 | 10 | AY.98 | 0.000079 |
N | 364 | P364L | cCa | cTa | 10 | 10 | B.1.258 | 0.000665 |
N | 364 | P364L | cCa | cTa | 9 | 9 | P.2 | 0.00168 |
N | 364 | P364L | cCa | cTa | 8 | 8 | AY.34 | 0.000776 |
N | 364 | P364L | cCa | cTa | 8 | 8 | B.1.1.214 | 0.000444 |
N | 364 | P364L | cCa | cTa | 8 | 8 | B.1.1.244 | 0.123077 |
N | 364 | P364L | cCa | cTa | 8 | 8 | B.1.351 | 0.000238 |
N | 364 | P364L | cCa | cTa | 8 | 8 | B.1.400 | 0.003432 |
N | 364 | P364L | cCa | cTa | 7 | 7 | AY.45 | 0.000852 |
N | 364 | P364L | cCa | cTa | 7 | 7 | B.1.221 | 0.000497 |
N | 364 | P364L | cCa | cTa | 7 | 7 | B.1.258.17 | 0.000728 |
N | 364 | P364L | cCa | cTa | 6 | 6 | AY.117 | 0.000507 |
N | 364 | P364L | cCa | cTa | 6 | 6 | AY.46 | 0.000624 |
N | 364 | P364L | cCa | cTa | 6 | 6 | AY.54 | 0.000572 |
N | 364 | P364L | cCa | cTa | 6 | 6 | B.1.1.519 | 0.000238 |
N | 364 | P364L | cCa | cTa | 6 | 6 | B.3 | 0.004983 |
N | 364 | P364L | cCa | cTa | 5 | 5 | AY.111 | 0.000916 |
N | 364 | P364L | cCa | cTa | 5 | 5 | AY.84 | 0.002187 |
N | 364 | P364L | cCa | cTa | 5 | 5 | B | 0.000639 |
N | 364 | P364L | cCa | cTa | 5 | 5 | B.1.1.50 | 0.003394 |
N | 364 | P364L | cCa | cTa | 5 | 5 | B.1.621 | 0.000443 |
N | 364 | P364L | cCa | cTa | 4 | 4 | AY.105 | 0.002572 |
N | 364 | P364L | cCa | cTa | 4 | 4 | AY.120 | 0.000149 |
N | 364 | P364L | cCa | cTa | 4 | 4 | AY.21 | 0.00759 |
N | 364 | P364L | cCa | cTa | 4 | 4 | AY.29 | 0.000063 |
N | 364 | P364L | cCa | cTa | 4 | 4 | AY.82 | 0.005427 |
N | 364 | P364L | cCa | cTa | 4 | 4 | B.1.1.409 | 0.011331 |
N | 364 | P364L | cCa | cTa | 4 | 4 | B.1.177 | 0.000053 |
N | 364 | P364L | cCa | cTa | 4 | 4 | B.1.243 | 0.000278 |
N | 364 | P364L | cCa | cTa | 3 | 3 | AY.34.1 | 0.00153 |
N | 364 | P364L | cCa | cTa | 3 | 3 | AY.59 | 0.001589 |
N | 364 | P364L | cCa | cTa | 3 | 3 | AY.74 | 0.000347 |
N | 364 | P364L | cCa | cTa | 3 | 3 | AY.78 | 0.004622 |
N | 364 | P364L | cCa | cTa | 3 | 3 | B.1.177.60 | 0.000655 |
N | 364 | P364L | cCa | cTa | 3 | 3 | B.1.177.73 | 0.001699 |
N | 364 | P364L | cCa | cTa | 3 | 3 | B.1.369 | 0.000856 |
N | 364 | P364L | cCa | cTa | 3 | 3 | B.1.466.2 | 0.001174 |
N | 364 | P364L | cCa | cTa | 2 | 2 | 0.111111 | |
N | 364 | P364L | cCa | cTa | 2 | 2 | A | 0.000774 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.100 | 0.000092 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.116 | 0.000574 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.13 | 0.000322 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.20 | 0.000078 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.23 | 0.000139 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.33 | 0.000134 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.5 | 0.000041 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.5.3 | 0.000675 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.51 | 0.001818 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.60 | 0.001876 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.64 | 0.00119 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.7 | 0.000392 |
N | 364 | P364L | cCa | cTa | 2 | 2 | AY.92 | 0.000575 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.1.311 | 0.000716 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.177.77 | 0.001452 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.346 | 0.002621 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.526 | 0.000047 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.588 | 0.00182 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.623 | 0.001073 |
N | 364 | P364L | cCa | cTa | 2 | 2 | B.1.628 | 0.000705 |
N | 364 | P364L | cCa | cTa | 2 | 2 | C.35 | 0.001548 |
N | 364 | P364L | cCa | cTa | 2 | 2 | C.37 | 0.000232 |
N | 364 | P364L | cCa | cTa | 2 | 2 | P.3 | 0.00319 |
N | 364 | P364L | cCa | cTa | 2 | 2 | P.4 | 0.007605 |
N | 364 | P364L | cCa | cTa | 2 | 2 | Q.1 | 0.000253 |
N | 364 | P364L | cCa | cTa | 1 | 1 | A.23 | 0.010526 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.108 | 0.001103 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.110 | 0.000113 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.118 | 0.000063 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.119 | 0.000035 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.120.1 | 0.000321 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.14 | 0.000088 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.27 | 0.000065 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.3.1 | 0.000085 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.42 | 0.00004 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.46.2 | 0.000635 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.46.4 | 0.000165 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.53 | 0.000288 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.68 | 0.000274 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.70 | 0.000209 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.75 | 0.000056 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.9 | 0.000068 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.9.1 | 0.000084 |
N | 364 | P364L | cCa | cTa | 1 | 1 | AY.99.2 | 0.000092 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.121 | 0.002427 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.153 | 0.001095 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.170 | 0.001247 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.251 | 0.007937 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.263 | 0.001558 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.28 | 0.000311 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.306 | 0.000438 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.335 | 0.012987 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.372 | 0.000689 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.398 | 0.003226 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.507 | 0.008696 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.63 | 0.000386 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.1.70 | 0.000341 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.142 | 0.002899 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.177.57 | 0.000281 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.177.81 | 0.000189 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.210 | 0.002132 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.214.2 | 0.0006 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.232 | 0.000537 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.234 | 0.000132 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.258.23 | 0.02381 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.279 | 0.000514 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.301 | 0.005917 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.351.5 | 0.0006 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.36.8 | 0.001 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.434 | 0.052632 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.499 | 0.00105 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.509 | 0.000866 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.517 | 0.000427 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.520 | 0.021739 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.524 | 0.001406 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.561 | 0.000397 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.612 | 0.002653 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.617.3 | 0.002985 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.627 | 0.00202 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.637 | 0.000073 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.1.8 | 0.001972 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.31 | 0.003731 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.4.4 | 0.018868 |
N | 364 | P364L | cCa | cTa | 1 | 1 | B.40 | 0.000364 |
N | 364 | P364L | cCa | cTa | 1 | 1 | C.30 | 0.001727 |
N | 364 | P364L | cCa | cTa | 1 | 1 | C.8 | 0.004464 |
N | 364 | P364L | cCa | cTa | 1 | 1 | D.2 | 0.000075 |
N | 364 | P364L | cCa | cTa | 1 | 1 | P.1.12 | 0.000484 |
N | 364 | P364L | cCa | cTa | 1 | 1 | P.1.15 | 0.000232 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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