CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = P162N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	162	P162N		nonsyn	CCt	AAt	74	42	0.567568	28757-28759
N	162	P162N		nonsyn	CCT	AAC	74	32	0.432432	28757-28759

Details of the mutation P162N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	162	P162N	CCt	AAt	42	74	All	0.000008
N	162	P162N	CCT	AAC	32	74	All	0.000006
N	162	P162N	CCt	AAt	18	30	B.1	0.000165
N	162	P162N	CCT	AAC	12	30	B.1	0.00011
N	162	P162N	CCt	AAt	5	9	B.1.177	0.000066
N	162	P162N	CCT	AAC	4	9	B.1.177	0.000053
N	162	P162N	CCt	AAt	4	7	B.1.1	0.000073
N	162	P162N	CCT	AAC	3	7	B.1.1	0.000054
N	162	P162N	CCt	AAt	3	6	B.1.258	0.0002
N	162	P162N	CCT	AAC	3	6	B.1.258	0.0002
N	162	P162N	CCT	AAC	2	4	B.1.2	0.000018
N	162	P162N	CCt	AAt	2	4	B.1.2	0.000018
N	162	P162N	CCt	AAt	2	3	B.1.160	0.000062
N	162	P162N	CCT	AAC	1	3	B.1.160	0.000031
N	162	P162N	CCt	AAt	1	2	B.1.1.170	0.001247
N	162	P162N	CCT	AAC	1	2	B.1.1.170	0.001247
N	162	P162N	CCt	AAt	1	2	B.1.1.39	0.00051
N	162	P162N	CCT	AAC	1	2	B.1.1.39	0.00051
N	162	P162N	CCT	AAC	1	2	B.1.1.515	0.02
N	162	P162N	CCt	AAt	1	2	B.1.1.515	0.02
N	162	P162N	CCt	AAt	1	2	B.1.177.86	0.000183
N	162	P162N	CCT	AAC	1	2	B.1.177.86	0.000183
N	162	P162N	CCT	AAC	1	2	B.1.221	0.000071
N	162	P162N	CCt	AAt	1	2	B.1.221	0.000071
N	162	P162N	CCt	AAt	1	2	B.1.525	0.000113
N	162	P162N	CCT	AAC	1	2	B.1.525	0.000113
N	162	P162N	CCt	AAt	1	2	B.1.78	0.008547
N	162	P162N	CCT	AAC	1	2	B.1.78	0.008547
N	162	P162N	CCt	AAt	1	1	B.1.1.7	0.000001

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.