CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = P162K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	162	P162K		nonsyn	CCT	AAA	34	28	0.823529	28757-28759
N	162	P162K		nonsyn	CCT	AAG	34	6	0.176471	28757-28759

Details of the mutation P162K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	162	P162K	CCT	AAA	28	34	All	0.000005
N	162	P162K	CCT	AAG	6	34	All	0.000001
N	162	P162K	CCT	AAA	11	15	B.1	0.000101
N	162	P162K	CCT	AAG	4	15	B.1	0.000037
N	162	P162K	CCT	AAA	4	4	B.1.177	0.000053
N	162	P162K	CCT	AAA	2	3	B.1.1	0.000036
N	162	P162K	CCT	AAG	1	3	B.1.1	0.000018
N	162	P162K	CCT	AAA	3	3	B.1.258	0.0002
N	162	P162K	CCT	AAA	2	2	B.1.160	0.000062
N	162	P162K	CCT	AAA	2	2	B.1.2	0.000018
N	162	P162K	CCT	AAA	1	1	B.1.1.170	0.001247
N	162	P162K	CCT	AAA	1	1	B.1.1.515	0.02
N	162	P162K	CCT	AAG	1	1	B.1.1.7	0.000001
N	162	P162K	CCT	AAA	1	1	B.1.221	0.000071
N	162	P162K	CCT	AAA	1	1	B.1.78	0.008547

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.