CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = P162C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	162	P162C		nonsyn	CCt	TGt	30	17	0.566667	28757-28759
N	162	P162C		nonsyn	CCT	TGC	30	13	0.433333	28757-28759

Details of the mutation P162C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	162	P162C	CCt	TGt	17	30	All	0.000003
N	162	P162C	CCT	TGC	13	30	All	0.000002
N	162	P162C	CCt	TGt	9	17	B.1	0.000082
N	162	P162C	CCT	TGC	8	17	B.1	0.000073
N	162	P162C	CCt	TGt	2	4	B.1.177	0.000026
N	162	P162C	CCT	TGC	2	4	B.1.177	0.000026
N	162	P162C	CCt	TGt	2	3	K.1	0.047619
N	162	P162C	CCT	TGC	1	3	K.1	0.02381
N	162	P162C	CCt	TGt	1	2	B.1.1.385	0.004464
N	162	P162C	CCT	TGC	1	2	B.1.1.385	0.004464
N	162	P162C	CCT	TGC	1	2	B.1.258	0.000067
N	162	P162C	CCt	TGt	1	2	B.1.258	0.000067
N	162	P162C	CCt	TGt	1	1	B.1.576	0.000907
N	162	P162C	CCt	TGt	1	1	B.1.609	0.000479

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.