CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 151 | P151L | nonsyn | cCt | cTt | 16417 | 16416 | 0.999939 | 28724-28726 | |
N | 151 | P151L | nonsyn | cCT | cTA | 16417 | 1 | 0.0000609125 | 28724-28726 |
Details of the mutation P151L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 151 | P151L | cCt | cTt | 16416 | 16417 | All | 0.00314 |
N | 151 | P151L | cCT | cTA | 1 | 16417 | All | 0 |
N | 151 | P151L | cCt | cTt | 9285 | 9285 | B.1.1.284 | 0.997208 |
N | 151 | P151L | cCt | cTt | 3088 | 3088 | B.1.1.7 | 0.002764 |
N | 151 | P151L | cCt | cTt | 1131 | 1131 | B.1.617.2 | 0.004259 |
N | 151 | P151L | cCt | cTt | 437 | 437 | AY.4 | 0.00068 |
N | 151 | P151L | cCt | cTt | 421 | 421 | AY.98 | 0.033257 |
N | 151 | P151L | cCt | cTt | 192 | 192 | AY.103 | 0.001192 |
N | 151 | P151L | cCt | cTt | 171 | 171 | B.1.1 | 0.003102 |
N | 151 | P151L | cCt | cTt | 165 | 166 | AY.44 | 0.001004 |
N | 151 | P151L | cCT | cTA | 1 | 166 | AY.44 | 0.000006 |
N | 151 | P151L | cCt | cTt | 140 | 140 | AY.39.1 | 0.005546 |
N | 151 | P151L | cCt | cTt | 82 | 82 | AY.120 | 0.003049 |
N | 151 | P151L | cCt | cTt | 80 | 80 | AY.20 | 0.003109 |
N | 151 | P151L | cCt | cTt | 77 | 77 | AY.43 | 0.000341 |
N | 151 | P151L | cCt | cTt | 71 | 71 | B.1.177 | 0.000935 |
N | 151 | P151L | cCt | cTt | 70 | 70 | AY.25 | 0.000421 |
N | 151 | P151L | cCt | cTt | 58 | 58 | D.2 | 0.004352 |
N | 151 | P151L | cCt | cTt | 52 | 52 | AY.3 | 0.000517 |
N | 151 | P151L | cCt | cTt | 35 | 35 | B.1 | 0.000321 |
N | 151 | P151L | cCt | cTt | 30 | 30 | B.1.1.160 | 0.714286 |
N | 151 | P151L | cCt | cTt | 28 | 28 | AY.5 | 0.000578 |
N | 151 | P151L | cCt | cTt | 28 | 28 | B.1.351 | 0.000832 |
N | 151 | P151L | cCt | cTt | 28 | 28 | B.1.427 | 0.001414 |
N | 151 | P151L | cCt | cTt | 28 | 28 | B.23 | 0.081871 |
N | 151 | P151L | cCt | cTt | 27 | 27 | B.1.2 | 0.000238 |
N | 151 | P151L | cCt | cTt | 25 | 25 | AY.4.2 | 0.000542 |
N | 151 | P151L | cCt | cTt | 24 | 24 | AY.46.6 | 0.001733 |
N | 151 | P151L | cCt | cTt | 24 | 24 | B.1.1.294 | 0.03038 |
N | 151 | P151L | cCt | cTt | 23 | 23 | AY.23 | 0.001604 |
N | 151 | P151L | cCt | cTt | 21 | 21 | B.1.429 | 0.000494 |
N | 151 | P151L | cCt | cTt | 20 | 20 | AY.102 | 0.00053 |
N | 151 | P151L | cCt | cTt | 19 | 19 | B.1.1.519 | 0.000755 |
N | 151 | P151L | cCt | cTt | 18 | 18 | P.1 | 0.000284 |
N | 151 | P151L | cCt | cTt | 17 | 17 | B.1.369 | 0.004849 |
N | 151 | P151L | cCt | cTt | 16 | 16 | AY.29 | 0.000252 |
N | 151 | P151L | cCt | cTt | 16 | 16 | AY.39 | 0.000395 |
N | 151 | P151L | cCt | cTt | 14 | 14 | B.1.597 | 0.064815 |
N | 151 | P151L | cCt | cTt | 12 | 12 | B.1.526 | 0.000282 |
N | 151 | P151L | cCt | cTt | 10 | 10 | AY.118 | 0.000626 |
N | 151 | P151L | cCt | cTt | 10 | 10 | AY.26 | 0.000283 |
N | 151 | P151L | cCt | cTt | 10 | 10 | AY.46.4 | 0.001645 |
N | 151 | P151L | cCt | cTt | 10 | 10 | B.1.160 | 0.000312 |
N | 151 | P151L | cCt | cTt | 9 | 9 | B.1.1.291 | 0.006682 |
N | 151 | P151L | cCt | cTt | 8 | 8 | AY.106 | 0.002679 |
N | 151 | P151L | cCt | cTt | 8 | 8 | AY.37 | 0.002528 |
N | 151 | P151L | cCt | cTt | 8 | 8 | B.1.1.135 | 0.037559 |
N | 151 | P151L | cCt | cTt | 7 | 7 | AY.119 | 0.000247 |
N | 151 | P151L | cCt | cTt | 7 | 7 | B.1.177.12 | 0.001062 |
N | 151 | P151L | cCt | cTt | 6 | 6 | AY.29.1 | 0.001323 |
N | 151 | P151L | cCt | cTt | 6 | 6 | AY.46.1 | 0.00616 |
N | 151 | P151L | cCt | cTt | 6 | 6 | AY.99 | 0.006296 |
N | 151 | P151L | cCt | cTt | 6 | 6 | B.1.1.420 | 0.006036 |
N | 151 | P151L | cCt | cTt | 6 | 6 | B.1.221 | 0.000426 |
N | 151 | P151L | cCt | cTt | 6 | 6 | B.1.348 | 0.109091 |
N | 151 | P151L | cCt | cTt | 6 | 6 | B.1.36 | 0.000875 |
N | 151 | P151L | cCt | cTt | 6 | 6 | C.37 | 0.000696 |
N | 151 | P151L | cCt | cTt | 5 | 5 | AY.42 | 0.000201 |
N | 151 | P151L | cCt | cTt | 5 | 5 | AY.6 | 0.000206 |
N | 151 | P151L | cCt | cTt | 5 | 5 | AY.9.2 | 0.000184 |
N | 151 | P151L | cCt | cTt | 5 | 5 | AY.95 | 0.003805 |
N | 151 | P151L | cCt | cTt | 5 | 5 | B.1.221.1 | 0.014535 |
N | 151 | P151L | cCt | cTt | 5 | 5 | B.1.568 | 0.005556 |
N | 151 | P151L | cCt | cTt | 5 | 5 | Q.8 | 0.000825 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.121 | 0.000541 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.3.1 | 0.000341 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.33 | 0.000267 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.45 | 0.000487 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.46 | 0.000416 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.5.4 | 0.001107 |
N | 151 | P151L | cCt | cTt | 4 | 4 | AY.68 | 0.001095 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.177.39 | 0.061538 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.214.4 | 0.036364 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.243 | 0.000278 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.36.18 | 0.001681 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.525 | 0.000453 |
N | 151 | P151L | cCt | cTt | 4 | 4 | B.1.621 | 0.000354 |
N | 151 | P151L | cCt | cTt | 4 | 4 | P.2 | 0.000747 |
N | 151 | P151L | cCt | cTt | 3 | 3 | AY.100 | 0.000138 |
N | 151 | P151L | cCt | cTt | 3 | 3 | AY.105 | 0.001929 |
N | 151 | P151L | cCt | cTt | 3 | 3 | AY.16 | 0.001139 |
N | 151 | P151L | cCt | cTt | 3 | 3 | AY.61 | 0.000314 |
N | 151 | P151L | cCt | cTt | 3 | 3 | AY.9 | 0.000203 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.1.253 | 0.007519 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.1.37 | 0.000579 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.1.434 | 0.001046 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.1.89 | 0.018182 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.177.4 | 0.000633 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.177.57 | 0.000843 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.177.82 | 0.001432 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.234 | 0.000396 |
N | 151 | P151L | cCt | cTt | 3 | 3 | B.1.428 | 0.003061 |
N | 151 | P151L | cCt | cTt | 3 | 3 | P.1.14 | 0.000143 |
N | 151 | P151L | cCt | cTt | 3 | 3 | Q.1 | 0.000379 |
N | 151 | P151L | cCt | cTt | 3 | 3 | R.1 | 0.00027 |
N | 151 | P151L | cCt | cTt | 2 | 2 | A | 0.000774 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.120.2 | 0.002571 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.16.1 | 0.00094 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.28 | 0.003781 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.32 | 0.001065 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.34 | 0.000194 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.35 | 0.000466 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.46.2 | 0.001271 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.48 | 0.00093 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.52 | 0.001629 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.7.1 | 0.000225 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.7.2 | 0.001119 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.75 | 0.000112 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.75.1 | 0.000361 |
N | 151 | P151L | cCt | cTt | 2 | 2 | AY.98.1 | 0.000097 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.1.214 | 0.000111 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.1.28 | 0.000622 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.1.280 | 0.006173 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.1.306 | 0.000877 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.1.56 | 0.035714 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.160.30 | 0.005952 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.177.81 | 0.000379 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.177.86 | 0.000367 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.258 | 0.000133 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.351.3 | 0.001753 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.36.17 | 0.000988 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.36.27 | 0.001527 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.371 | 0.002245 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.399 | 0.003868 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.466.2 | 0.000782 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.575 | 0.000607 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.609 | 0.000959 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.623 | 0.001073 |
N | 151 | P151L | cCt | cTt | 2 | 2 | B.1.637 | 0.000146 |
N | 151 | P151L | cCt | cTt | 2 | 2 | P.1.15 | 0.000465 |
N | 151 | P151L | cCt | cTt | 2 | 2 | P.1.16 | 0.000748 |
N | 151 | P151L | cCt | cTt | 1 | 1 | A.2.2 | 0.001689 |
N | 151 | P151L | cCt | cTt | 1 | 1 | A.2.5 | 0.000499 |
N | 151 | P151L | cCt | cTt | 1 | 1 | A.2.5.2 | 0.001572 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AD.2 | 0.000219 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AE.8 | 0.000489 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AU.2 | 0.002421 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.101 | 0.00049 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.109 | 0.00074 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.11 | 0.001339 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.110 | 0.000113 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.117 | 0.000085 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.12 | 0.000316 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.2 | 0.000356 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.34.1 | 0.00051 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.4.2.1 | 0.000149 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.47 | 0.000031 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.53 | 0.000288 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.63 | 0.000387 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.65 | 0.000533 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.69 | 0.000187 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.7 | 0.000196 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.73 | 0.000665 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.74 | 0.000116 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.8 | 0.000606 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.9.1 | 0.000084 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.92 | 0.000287 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.93 | 0.000273 |
N | 151 | P151L | cCt | cTt | 1 | 1 | AY.99.2 | 0.000092 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.1 | 0.000327 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.10 | 0.001115 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.153 | 0.001095 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.222 | 0.000204 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.236 | 0.006897 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.25 | 0.000569 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.266 | 0.012195 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.279 | 0.001121 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.312 | 0.001912 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.317 | 0.000412 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.33 | 0.000421 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.348 | 0.000796 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.369 | 0.000446 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.378 | 0.007299 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.487 | 0.005587 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.50 | 0.000679 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.52 | 0.012195 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.1.70 | 0.000341 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.110.3 | 0.000718 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.112 | 0.005181 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.10 | 0.000878 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.16 | 0.000664 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.17 | 0.000821 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.35 | 0.000691 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.54 | 0.000606 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.55 | 0.002331 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.58 | 0.001332 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.65 | 0.000665 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.177.8 | 0.000752 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.239 | 0.001221 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.281 | 0.021739 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.311 | 0.000275 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.356 | 0.001727 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.36.1 | 0.00114 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.36.22 | 0.001208 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.36.24 | 0.006173 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.367 | 0.000792 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.396 | 0.000706 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.416 | 0.001269 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.436 | 0.001029 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.448 | 0.002625 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.468 | 0.005714 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.503 | 0.002488 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.541 | 0.004425 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.560 | 0.00463 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.561 | 0.000397 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.564 | 0.000426 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.564.1 | 0.001577 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.577 | 0.000687 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.582 | 0.000491 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.596 | 0.000087 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.605 | 0.005952 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.617.1 | 0.000129 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.627 | 0.00202 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.630 | 0.005236 |
N | 151 | P151L | cCt | cTt | 1 | 1 | B.1.9.5 | 0.005682 |
N | 151 | P151L | cCt | cTt | 1 | 1 | C.1 | 0.002392 |
N | 151 | P151L | cCt | cTt | 1 | 1 | C.14 | 0.004329 |
N | 151 | P151L | cCt | cTt | 1 | 1 | C.3 | 0.007634 |
N | 151 | P151L | cCt | cTt | 1 | 1 | C.36 | 0.000911 |
N | 151 | P151L | cCt | cTt | 1 | 1 | D.5 | 0.004975 |
N | 151 | P151L | cCt | cTt | 1 | 1 | N.5 | 0.001767 |
N | 151 | P151L | cCt | cTt | 1 | 1 | P.1.2 | 0.001156 |
N | 151 | P151L | cCt | cTt | 1 | 1 | Q.2 | 0.000613 |
N | 151 | P151L | cCt | cTt | 1 | 1 | Q.3 | 0.000145 |
N | 151 | P151L | cCt | cTt | 1 | 1 | U.2 | 0.008772 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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