CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = M1X

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	1	M1X		nonsyn	ATG	TAA	270	171	0.633333	28274-28276
N	1	M1X		nonsyn	ATg	TAg	270	99	0.366667	28274-28276

Details of the mutation M1X within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	1	M1X	ATG	TAA	171	270	All	0.000033
N	1	M1X	ATg	TAg	99	270	All	0.000019
N	1	M1X	ATG	TAA	118	204	P.1	0.001859
N	1	M1X	ATg	TAg	86	204	P.1	0.001355
N	1	M1X	ATG	TAA	19	20	P.1.12	0.009197
N	1	M1X	ATg	TAg	1	20	P.1.12	0.000484
N	1	M1X	ATG	TAA	17	17	P.1.17	0.00275
N	1	M1X	ATG	TAA	6	12	P.1.4	0.005859
N	1	M1X	ATg	TAg	6	12	P.1.4	0.005859
N	1	M1X	ATG	TAA	3	6	P.1.2	0.003468
N	1	M1X	ATg	TAg	3	6	P.1.2	0.003468
N	1	M1X	ATG	TAA	4	5	P.1.10	0.001078
N	1	M1X	ATg	TAg	1	5	P.1.10	0.000269
N	1	M1X	ATG	TAA	2	4	P.1.15	0.000465
N	1	M1X	ATg	TAg	2	4	P.1.15	0.000465
N	1	M1X	ATG	TAA	1	1	P.1.13	0.000898
N	1	M1X	ATG	TAA	1	1	P.1.14	0.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.