CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = K257K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	257	K257K		syn	aaG	aaA	3717	3717	1	29042-29044

Details of the mutation K257K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	257	K257K	aaG	aaA	3717	3717	All	0.000711
N	257	K257K	aaG	aaA	1641	1641	B.1.1.7	0.001469
N	257	K257K	aaG	aaA	988	988	B.1.389	0.98998
N	257	K257K	aaG	aaA	163	163	B.1.1.284	0.017506
N	257	K257K	aaG	aaA	124	124	B.1	0.001136
N	257	K257K	aaG	aaA	116	116	AY.9	0.007841
N	257	K257K	aaG	aaA	97	97	B.1.497	0.030532
N	257	K257K	aaG	aaA	91	91	Q.8	0.015007
N	257	K257K	aaG	aaA	61	61	B.1.617.2	0.00023
N	257	K257K	aaG	aaA	60	60	AY.44	0.000365
N	257	K257K	aaG	aaA	35	35	AY.43	0.000155
N	257	K257K	aaG	aaA	33	33	AY.4	0.000051
N	257	K257K	aaG	aaA	26	26	B.1.177	0.000342
N	257	K257K	aaG	aaA	23	23	AY.103	0.000143
N	257	K257K	aaG	aaA	23	23	B.1.1.519	0.000913
N	257	K257K	aaG	aaA	23	23	C.37	0.002669
N	257	K257K	aaG	aaA	20	20	B.1.2	0.000176
N	257	K257K	aaG	aaA	13	13	AY.3	0.000129
N	257	K257K	aaG	aaA	12	12	B.1.218	0.061856
N	257	K257K	aaG	aaA	9	9	AY.50	0.007194
N	257	K257K	aaG	aaA	8	8	AY.25	0.000048
N	257	K257K	aaG	aaA	8	8	B.1.637	0.000585
N	257	K257K	aaG	aaA	8	8	P.1.7	0.002554
N	257	K257K	aaG	aaA	7	7	P.1	0.00011
N	257	K257K	aaG	aaA	6	6	AY.5	0.000124
N	257	K257K	aaG	aaA	6	6	B.1.1	0.000109
N	257	K257K	aaG	aaA	5	5	AY.117	0.000423
N	257	K257K	aaG	aaA	5	5	AY.13	0.000805
N	257	K257K	aaG	aaA	5	5	B.1.609	0.002397
N	257	K257K	aaG	aaA	4	4	Q.1	0.000505
N	257	K257K	aaG	aaA	3	3	AU.3	0.006329
N	257	K257K	aaG	aaA	3	3	AY.102	0.00008
N	257	K257K	aaG	aaA	3	3	AY.120	0.000112
N	257	K257K	aaG	aaA	3	3	AY.34	0.000291
N	257	K257K	aaG	aaA	3	3	AY.74	0.000347
N	257	K257K	aaG	aaA	3	3	B.1.1.216	0.002671
N	257	K257K	aaG	aaA	3	3	B.1.258	0.0002
N	257	K257K	aaG	aaA	3	3	B.1.36.39	0.006652
N	257	K257K	aaG	aaA	3	3	B.1.427	0.000151
N	257	K257K	aaG	aaA	3	3	B.1.509	0.002597
N	257	K257K	aaG	aaA	3	3	P.1.16	0.001122
N	257	K257K	aaG	aaA	2	2		0.111111
N	257	K257K	aaG	aaA	2	2	AY.106	0.00067
N	257	K257K	aaG	aaA	2	2	AY.119	0.000071
N	257	K257K	aaG	aaA	2	2	AY.26	0.000057
N	257	K257K	aaG	aaA	2	2	AY.65	0.001066
N	257	K257K	aaG	aaA	2	2	AY.69	0.000373
N	257	K257K	aaG	aaA	2	2	AY.75	0.000112
N	257	K257K	aaG	aaA	2	2	AY.98	0.000158
N	257	K257K	aaG	aaA	2	2	B.1.1.326	0.003521
N	257	K257K	aaG	aaA	2	2	B.1.1.33	0.000842
N	257	K257K	aaG	aaA	2	2	B.1.1.70	0.000682
N	257	K257K	aaG	aaA	2	2	B.1.177.81	0.000379
N	257	K257K	aaG	aaA	2	2	B.1.400	0.000858
N	257	K257K	aaG	aaA	2	2	B.1.600	0.011696
N	257	K257K	aaG	aaA	2	2	B.1.621	0.000177
N	257	K257K	aaG	aaA	2	2	P.1.12	0.000968
N	257	K257K	aaG	aaA	1	1	AE.8	0.000489
N	257	K257K	aaG	aaA	1	1	AY.12	0.000316
N	257	K257K	aaG	aaA	1	1	AY.20	0.000039
N	257	K257K	aaG	aaA	1	1	AY.4.2	0.000022
N	257	K257K	aaG	aaA	1	1	AY.45	0.000122
N	257	K257K	aaG	aaA	1	1	AY.46	0.000104
N	257	K257K	aaG	aaA	1	1	AY.46.5	0.000198
N	257	K257K	aaG	aaA	1	1	AY.47	0.000031
N	257	K257K	aaG	aaA	1	1	AY.75.1	0.00018
N	257	K257K	aaG	aaA	1	1	AY.98.1	0.000048
N	257	K257K	aaG	aaA	1	1	AY.99.2	0.000092
N	257	K257K	aaG	aaA	1	1	B.1.1.273	0.006757
N	257	K257K	aaG	aaA	1	1	B.1.1.297	0.002237
N	257	K257K	aaG	aaA	1	1	B.1.128	0.000635
N	257	K257K	aaG	aaA	1	1	B.1.13	0.002375
N	257	K257K	aaG	aaA	1	1	B.1.177.73	0.000566
N	257	K257K	aaG	aaA	1	1	B.1.177.84	0.006667
N	257	K257K	aaG	aaA	1	1	B.1.243	0.00007
N	257	K257K	aaG	aaA	1	1	B.1.258.17	0.000104
N	257	K257K	aaG	aaA	1	1	B.1.36	0.000146
N	257	K257K	aaG	aaA	1	1	B.1.429	0.000024
N	257	K257K	aaG	aaA	1	1	B.1.466.2	0.000391
N	257	K257K	aaG	aaA	1	1	B.1.525	0.000113
N	257	K257K	aaG	aaA	1	1	B.1.526	0.000024
N	257	K257K	aaG	aaA	1	1	B.1.541	0.004425
N	257	K257K	aaG	aaA	1	1	B.1.595	0.000261
N	257	K257K	aaG	aaA	1	1	B.1.617.3	0.002985
N	257	K257K	aaG	aaA	1	1	B.4.6	0.016667
N	257	K257K	aaG	aaA	1	1	D.2	0.000075
N	257	K257K	aaG	aaA	1	1	P.1.14	0.000048
N	257	K257K	aaG	aaA	1	1	P.1.17.1	0.000875
N	257	K257K	aaG	aaA	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.