CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = I292T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	292	I292T		nonsyn	aTc	aCc	4675	4520	0.966845	29147-29149
N	292	I292T		nonsyn	aTC	aCT	4675	155	0.0331551	29147-29149

Details of the mutation I292T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	292	I292T	aTc	aCc	4520	4675	All	0.000865
N	292	I292T	aTC	aCT	155	4675	All	0.00003
N	292	I292T	aTc	aCc	2353	2363	B.1.1.33	0.99032
N	292	I292T	aTC	aCT	10	2363	B.1.1.33	0.004209
N	292	I292T	aTc	aCc	395	538	N.5	0.69788
N	292	I292T	aTC	aCT	143	538	N.5	0.25265
N	292	I292T	aTc	aCc	234	235	N.4	0.995745
N	292	I292T	aTC	aCT	1	235	N.4	0.004255
N	292	I292T	aTc	aCc	229	229	B.1.1	0.004154
N	292	I292T	aTc	aCc	172	172	N.3	1
N	292	I292T	aTc	aCc	164	164	N.9	0.97619
N	292	I292T	aTc	aCc	140	140	N.6	0.992908
N	292	I292T	aTc	aCc	127	127	B.1.1.7	0.000114
N	292	I292T	aTc	aCc	96	96	B.1.160.16	0.089219
N	292	I292T	aTc	aCc	83	84	B.1	0.00076
N	292	I292T	aTC	aCT	1	84	B.1	0.000009
N	292	I292T	aTc	aCc	42	42	N.1	0.711864
N	292	I292T	aTc	aCc	34	34	N.10	1
N	292	I292T	aTc	aCc	34	34	N.7	1
N	292	I292T	aTc	aCc	32	32	N.8	1
N	292	I292T	aTc	aCc	31	31	AY.25	0.000186
N	292	I292T	aTc	aCc	26	26	AK.1	0.329114
N	292	I292T	aTc	aCc	26	26	AY.4	0.00004
N	292	I292T	aTc	aCc	26	26	N.2	1
N	292	I292T	aTc	aCc	19	19	B.1.139	0.01393
N	292	I292T	aTc	aCc	19	19	B.1.177.44	0.00986
N	292	I292T	aTc	aCc	18	18	AY.44	0.00011
N	292	I292T	aTc	aCc	17	17	B.1.1.519	0.000675
N	292	I292T	aTc	aCc	10	10	B.1.2	0.000088
N	292	I292T	aTc	aCc	10	10	B.1.617.2	0.000038
N	292	I292T	aTc	aCc	9	9	AY.3	0.00009
N	292	I292T	aTc	aCc	9	9	B.1.160	0.000281
N	292	I292T	aTc	aCc	9	9	B.1.351	0.000268
N	292	I292T	aTc	aCc	8	8	B.1.177.75	0.008325
N	292	I292T	aTc	aCc	8	8	B.1.429	0.000188
N	292	I292T	aTc	aCc	7	7	AY.102	0.000186
N	292	I292T	aTc	aCc	7	7	B.1.1.393	0.777778
N	292	I292T	aTc	aCc	7	7	B.1.177	0.000092
N	292	I292T	aTc	aCc	7	7	B.1.609	0.003356
N	292	I292T	aTc	aCc	7	7	P.1	0.00011
N	292	I292T	aTc	aCc	6	6	AY.43	0.000027
N	292	I292T	aTc	aCc	6	6	AZ.5	0.021053
N	292	I292T	aTc	aCc	6	6	B.1.1.28	0.001867
N	292	I292T	aTc	aCc	5	5	AY.34	0.000485
N	292	I292T	aTc	aCc	4	4	AY.75	0.000224
N	292	I292T	aTc	aCc	4	4	B.1.221	0.000284
N	292	I292T	aTc	aCc	3	3	AY.20	0.000117
N	292	I292T	aTc	aCc	3	3	AY.42	0.000121
N	292	I292T	aTc	aCc	3	3	B.1.1.303	0.008287
N	292	I292T	aTc	aCc	2	2		0.111111
N	292	I292T	aTc	aCc	2	2	AY.119	0.000071
N	292	I292T	aTc	aCc	2	2	AY.29	0.000032
N	292	I292T	aTc	aCc	2	2	AY.39	0.000049
N	292	I292T	aTc	aCc	2	2	AY.46.2	0.001271
N	292	I292T	aTc	aCc	2	2	AY.47	0.000062
N	292	I292T	aTc	aCc	2	2	B.1.1.318	0.000604
N	292	I292T	aTc	aCc	2	2	B.1.36.18	0.00084
N	292	I292T	aTc	aCc	2	2	B.1.499	0.002101
N	292	I292T	aTc	aCc	2	2	B.1.526	0.000047
N	292	I292T	aTc	aCc	2	2	B.1.596	0.000174
N	292	I292T	aTc	aCc	2	2	B.4	0.004415
N	292	I292T	aTc	aCc	1	1	A.2	0.000662
N	292	I292T	aTc	aCc	1	1	AY.103	0.000006
N	292	I292T	aTc	aCc	1	1	AY.117	0.000085
N	292	I292T	aTc	aCc	1	1	AY.13	0.000161
N	292	I292T	aTc	aCc	1	1	AY.2	0.000356
N	292	I292T	aTc	aCc	1	1	AY.23	0.00007
N	292	I292T	aTc	aCc	1	1	AY.26	0.000028
N	292	I292T	aTc	aCc	1	1	AY.39.1	0.00004
N	292	I292T	aTc	aCc	1	1	AY.46.1	0.001027
N	292	I292T	aTc	aCc	1	1	AY.68	0.000274
N	292	I292T	aTc	aCc	1	1	AY.73	0.000665
N	292	I292T	aTc	aCc	1	1	AY.79	0.001211
N	292	I292T	aTc	aCc	1	1	AY.9.2	0.000037
N	292	I292T	aTc	aCc	1	1	AY.93	0.000273
N	292	I292T	aTc	aCc	1	1	AY.98.1	0.000048
N	292	I292T	aTc	aCc	1	1	AY.99.2	0.000092
N	292	I292T	aTc	aCc	1	1	B.1.1.27	0.00565
N	292	I292T	aTc	aCc	1	1	B.1.1.332	0.03125
N	292	I292T	aTc	aCc	1	1	B.1.1.356	0.008547
N	292	I292T	aTc	aCc	1	1	B.1.1.362	0.005618
N	292	I292T	aTc	aCc	1	1	B.1.1.70	0.000341
N	292	I292T	aTc	aCc	1	1	B.1.104	0.00369
N	292	I292T	aTc	aCc	1	1	B.1.170	0.00431
N	292	I292T	aTc	aCc	1	1	B.1.177.51	0.004566
N	292	I292T	aTc	aCc	1	1	B.1.177.73	0.000566
N	292	I292T	aTc	aCc	1	1	B.1.201	0.005682
N	292	I292T	aTc	aCc	1	1	B.1.258	0.000067
N	292	I292T	aTc	aCc	1	1	B.1.404	0.001302
N	292	I292T	aTc	aCc	1	1	B.1.459	0.004082
N	292	I292T	aTc	aCc	1	1	B.1.466.2	0.000391
N	292	I292T	aTc	aCc	1	1	B.1.479	0.038462
N	292	I292T	aTc	aCc	1	1	B.1.621	0.000089
N	292	I292T	aTc	aCc	1	1	B.1.91	0.002075
N	292	I292T	aTc	aCc	1	1	C.1.2	0.004255
N	292	I292T	aTc	aCc	1	1	C.27	0.018519
N	292	I292T	aTc	aCc	1	1	C.37	0.000116
N	292	I292T	aTc	aCc	1	1	C.39	0.018868
N	292	I292T	aTc	aCc	1	1	P.1.12	0.000484
N	292	I292T	aTc	aCc	1	1	P.1.15	0.000232
N	292	I292T	aTc	aCc	1	1	P.1.7	0.000319
N	292	I292T	aTc	aCc	1	1	P.2	0.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.