CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = N : Mut = G204L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
N204G204LnonsynGGaCTa292929220.9976128883-28885
N204G204LnonsynGGaTTa292950.0017070728883-28885
N204G204LnonsynGGACTT292920.00068282728883-28885

Details of the mutation G204L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
N204G204LGGaCTa29222929All0.000559
N204G204LGGaTTa52929All0.000001
N204G204LGGACTT22929All0
N204G204LGGaCTa773773B.1.10.014023
N204G204LGGaCTa536536B.1.1.1530.587076
N204G204LGGaCTa423423B.1.1.70.000379
N204G204LGGaCTa415415B.1.1.441
N204G204LGGaCTa278278AM.40.992857
N204G204LGGaCTa7777P.10.001213
N204G204LGGaCTa6161B.1.1.370.011765
N204G204LGGaCTa4242B.1.1.3040.117978
N204G204LGGaCTa3939B.1.1.4320.049367
N204G204LGGaCTa3434B.1.1.1940.168317
N204G204LGGaCTa2020P.20.003733
N204G204LGGaCTa1317B.10.000119
N204G204LGGaTTa217B.10.000018
N204G204LGGACTT217B.10.000018
N204G204LGGaCTa1717P.1.140.000813
N204G204LGGaCTa1111B.1.1.2320.019964
N204G204LGGaCTa1010B.1.1.2140.000555
N204G204LGGaCTa88B.1.1.2200.01487
N204G204LGGaCTa88B.1.1.4160.00724
N204G204LGGaCTa77B.1.1.2220.001428
N204G204LGGaCTa77Q.80.001154
N204G204LGGaCTa66B.1.1.280.001867
N204G204LGGaCTa55B.1.1.100.005574
N204G204LGGaCTa55B.1.1.1760.002197
N204G204LGGaCTa55B.1.1.2160.004452
N204G204LGGaCTa55B.1.1.4030.128205
N204G204LGGaCTa44B.1.1.1740.013514
N204G204LGGaCTa44B.1.1.3440.043011
N204G204LGGaCTa44B.1.1.4640.005891
N204G204LGGaCTa44B.1.1.5190.000159
N204G204LGGaCTa44C.370.000464
N204G204LGGaCTa44D.20.0003
N204G204LGGaCTa44P.1.150.000929
N204G204LGGaCTa44P.1.70.001277
N204G204LGGaCTa33B.1.1.2280.009146
N204G204LGGaCTa33B.1.1.250.001706
N204G204LGGaCTa33B.1.1.2890.00625
N204G204LGGaCTa33B.1.1.2940.003797
N204G204LGGaCTa33B.1.1.4340.001046
N204G204LGGaCTa33B.1.1.5210.016043
N204G204LGGaCTa22B.1.1.1280.014184
N204G204LGGaCTa22B.1.1.1410.004024
N204G204LGGaCTa22B.1.1.1710.007353
N204G204LGGaCTa22B.1.1.1890.003026
N204G204LGGaCTa22B.1.1.3060.000877
N204G204LGGaCTa22B.1.1.3070.005063
N204G204LGGaCTa22B.1.1.3110.000716
N204G204LGGaCTa22B.1.1.3170.000823
N204G204LGGaCTa22B.1.1.3260.003521
N204G204LGGaCTa22B.1.1.3720.001377
N204G204LGGaCTa22B.1.1.3760.011905
N204G204LGGaCTa22B.1.1.3980.006452
N204G204LGGaCTa22B.1.1.4480.004065
N204G204LGGaCTa22B.1.1.630.000772
N204G204LGGaCTa22P.1.100.000539
N204G204LGGaCTa22P.1.120.000968
N204G204LGGaCTa11AE.30.032258
N204G204LGGaCTa11AE.80.000489
N204G204LGGaCTa11AY.430.000004
N204G204LGGaTTa11AY.440.000006
N204G204LGGaTTa11AY.610.000105
N204G204LGGaCTa11B0.000128
N204G204LGGaCTa11B.1.1.1210.002427
N204G204LGGaCTa11B.1.1.1590.004673
N204G204LGGaCTa11B.1.1.1610.003534
N204G204LGGaCTa11B.1.1.2000.007463
N204G204LGGaCTa11B.1.1.2410.00207
N204G204LGGaCTa11B.1.1.2630.001558
N204G204LGGaCTa11B.1.1.2740.005051
N204G204LGGaCTa11B.1.1.3160.000925
N204G204LGGaCTa11B.1.1.330.000421
N204G204LGGaCTa11B.1.1.3630.005988
N204G204LGGaCTa11B.1.1.3680.003086
N204G204LGGaCTa11B.1.1.3710.010417
N204G204LGGaCTa11B.1.1.3740.002375
N204G204LGGaCTa11B.1.1.3780.007299
N204G204LGGaCTa11B.1.1.4170.002703
N204G204LGGaCTa11B.1.1.4870.005587
N204G204LGGaCTa11B.1.1.610.008772
N204G204LGGaCTa11B.1.1.740.00431
N204G204LGGaCTa11B.1.1770.000013
N204G204LGGaCTa11B.1.2350.002519
N204G204LGGaTTa11B.1.4220.000812
N204G204LGGaCTa11B.1.617.20.000004
N204G204LGGaCTa11C.20.016129
N204G204LGGaCTa11C.50.090909
N204G204LGGaCTa11N.90.005952
N204G204LGGaCTa11P.1.10.000318
N204G204LGGaCTa11P.1.160.000374
N204G204LGGaCTa11P.1.170.000162
N204G204LGGaCTa11P.1.40.000977
N204G204LGGaCTa11P.30.001595
N204G204LGGaCTa11Q.30.000145
N204G204LGGaCTa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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