CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = G179S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	179	G179S		nonsyn	Ggc	Agc	2762	2759	0.998914	28808-28810
N	179	G179S		nonsyn	GgC	AgT	2762	2	0.000724113	28808-28810
N	179	G179S		nonsyn	GGc	TCc	2762	1	0.000362056	28808-28810

Details of the mutation G179S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	179	G179S	Ggc	Agc	2759	2762	All	0.000528
N	179	G179S	GgC	AgT	2	2762	All	0
N	179	G179S	GGc	TCc	1	2762	All	0
N	179	G179S	Ggc	Agc	860	860	AY.103	0.00534
N	179	G179S	Ggc	Agc	310	310	B.1.617.2	0.001167
N	179	G179S	Ggc	Agc	226	228	B.1.1.7	0.000202
N	179	G179S	GgC	AgT	2	228	B.1.1.7	0.000002
N	179	G179S	Ggc	Agc	162	162	AY.47	0.005039
N	179	G179S	Ggc	Agc	157	157	AY.44	0.000956
N	179	G179S	Ggc	Agc	149	149	AY.99.2	0.013731
N	179	G179S	Ggc	Agc	91	91	AY.4	0.000142
N	179	G179S	Ggc	Agc	85	85	AY.43	0.000377
N	179	G179S	Ggc	Agc	52	52	AY.25	0.000313
N	179	G179S	Ggc	Agc	47	47	AY.29	0.000741
N	179	G179S	Ggc	Agc	43	43	B.1.480	0.106965
N	179	G179S	Ggc	Agc	39	39	AY.3	0.000388
N	179	G179S	Ggc	Agc	35	35	AY.102	0.000928
N	179	G179S	Ggc	Agc	34	34	AY.39	0.00084
N	179	G179S	Ggc	Agc	33	33	B.1.2	0.000291
N	179	G179S	Ggc	Agc	31	31	B.1.1.316	0.028677
N	179	G179S	Ggc	Agc	29	29	B.1.334	0.527273
N	179	G179S	Ggc	Agc	22	22	AY.5	0.000454
N	179	G179S	Ggc	Agc	21	21	B.1.177	0.000277
N	179	G179S	Ggc	Agc	19	19	AY.12	0.006005
N	179	G179S	Ggc	Agc	18	18	AY.26	0.00051
N	179	G179S	Ggc	Agc	16	16	AY.38	0.007988
N	179	G179S	Ggc	Agc	15	15	P.1.14	0.000717
N	179	G179S	Ggc	Agc	14	14	B.1.160	0.000437
N	179	G179S	Ggc	Agc	13	13	AY.119	0.000459
N	179	G179S	Ggc	Agc	13	13	P.1	0.000205
N	179	G179S	Ggc	Agc	9	9	B.1.1.241	0.018634
N	179	G179S	Ggc	Agc	7	7	AY.117	0.000592
N	179	G179S	Ggc	Agc	7	7	AY.20	0.000272
N	179	G179S	Ggc	Agc	7	7	AY.4.2	0.000152
N	179	G179S	Ggc	Agc	7	7	B.1.177.4	0.001477
N	179	G179S	Ggc	Agc	7	7	B.1.429	0.000165
N	179	G179S	Ggc	Agc	6	6	AY.23	0.000418
N	179	G179S	Ggc	Agc	6	6	AY.46	0.000624
N	179	G179S	Ggc	Agc	6	6	B.1	0.000055
N	179	G179S	Ggc	Agc	5	5	AY.75.1	0.000902
N	179	G179S	Ggc	Agc	5	5	B.1.1	0.000091
N	179	G179S	Ggc	Agc	5	5	B.1.351	0.000149
N	179	G179S	Ggc	Agc	4	4	AY.100	0.000184
N	179	G179S	Ggc	Agc	4	4	AY.110	0.000451
N	179	G179S	Ggc	Agc	4	4	AY.27	0.000259
N	179	G179S	Ggc	Agc	4	4	AY.9.2	0.000147
N	179	G179S	Ggc	Agc	4	4	AY.98	0.000316
N	179	G179S	Ggc	Agc	4	4	AY.98.1	0.000194
N	179	G179S	Ggc	Agc	3	3	AY.45	0.000365
N	179	G179S	Ggc	Agc	3	3	AY.46.6	0.000217
N	179	G179S	Ggc	Agc	3	3	AY.61	0.000314
N	179	G179S	Ggc	Agc	3	3	AY.77	0.003382
N	179	G179S	Ggc	Agc	3	3	B.1.1.25	0.001706
N	179	G179S	Ggc	Agc	2	3	B.1.36	0.000292
N	179	G179S	GGc	TCc	1	3	B.1.36	0.000146
N	179	G179S	Ggc	Agc	3	3	P.2	0.00056
N	179	G179S	Ggc	Agc	2	2	AD.1	0.00823
N	179	G179S	Ggc	Agc	2	2	AY.120	0.000074
N	179	G179S	Ggc	Agc	2	2	AY.120.2.1	0.000997
N	179	G179S	Ggc	Agc	2	2	AY.19	0.002281
N	179	G179S	Ggc	Agc	2	2	AY.3.1	0.000171
N	179	G179S	Ggc	Agc	2	2	AY.34	0.000194
N	179	G179S	Ggc	Agc	2	2	AY.42	0.00008
N	179	G179S	Ggc	Agc	2	2	AY.5.4	0.000553
N	179	G179S	Ggc	Agc	2	2	AY.58	0.001815
N	179	G179S	Ggc	Agc	2	2	AY.88	0.001768
N	179	G179S	Ggc	Agc	2	2	AY.9	0.000135
N	179	G179S	Ggc	Agc	2	2	B.1.1.222	0.000408
N	179	G179S	Ggc	Agc	2	2	B.1.1.277	0.001517
N	179	G179S	Ggc	Agc	2	2	B.1.1.298	0.001724
N	179	G179S	Ggc	Agc	2	2	B.1.1.317	0.000823
N	179	G179S	Ggc	Agc	2	2	B.1.1.39	0.001019
N	179	G179S	Ggc	Agc	2	2	B.1.1.434	0.000697
N	179	G179S	Ggc	Agc	2	2	B.1.1.519	0.000079
N	179	G179S	Ggc	Agc	2	2	B.1.177.21	0.000153
N	179	G179S	Ggc	Agc	2	2	B.1.221.1	0.005814
N	179	G179S	Ggc	Agc	2	2	B.1.258.16	0.003273
N	179	G179S	Ggc	Agc	2	2	B.1.427	0.000101
N	179	G179S	Ggc	Agc	2	2	B.1.526	0.000047
N	179	G179S	Ggc	Agc	2	2	N.6	0.014184
N	179	G179S	Ggc	Agc	2	2	P.1.15	0.000465
N	179	G179S	Ggc	Agc	2	2	Q.8	0.00033
N	179	G179S	Ggc	Agc	1	1		0.055556
N	179	G179S	Ggc	Agc	1	1	AY.111	0.000183
N	179	G179S	Ggc	Agc	1	1	AY.118	0.000063
N	179	G179S	Ggc	Agc	1	1	AY.13	0.000161
N	179	G179S	Ggc	Agc	1	1	AY.14	0.000088
N	179	G179S	Ggc	Agc	1	1	AY.15	0.002222
N	179	G179S	Ggc	Agc	1	1	AY.2	0.000356
N	179	G179S	Ggc	Agc	1	1	AY.23.1	0.000417
N	179	G179S	Ggc	Agc	1	1	AY.28	0.00189
N	179	G179S	Ggc	Agc	1	1	AY.33	0.000067
N	179	G179S	Ggc	Agc	1	1	AY.36	0.000148
N	179	G179S	Ggc	Agc	1	1	AY.37	0.000316
N	179	G179S	Ggc	Agc	1	1	AY.4.5	0.000107
N	179	G179S	Ggc	Agc	1	1	AY.40	0.000964
N	179	G179S	Ggc	Agc	1	1	AY.46.1	0.001027
N	179	G179S	Ggc	Agc	1	1	AY.46.4	0.000165
N	179	G179S	Ggc	Agc	1	1	AY.5.3	0.000337
N	179	G179S	Ggc	Agc	1	1	AY.54	0.000095
N	179	G179S	Ggc	Agc	1	1	AY.55	0.000917
N	179	G179S	Ggc	Agc	1	1	AY.64	0.000595
N	179	G179S	Ggc	Agc	1	1	AY.65	0.000533
N	179	G179S	Ggc	Agc	1	1	AY.7.1	0.000113
N	179	G179S	Ggc	Agc	1	1	AY.73	0.000665
N	179	G179S	Ggc	Agc	1	1	AY.75	0.000056
N	179	G179S	Ggc	Agc	1	1	AY.82	0.001357
N	179	G179S	Ggc	Agc	1	1	AY.85	0.000427
N	179	G179S	Ggc	Agc	1	1	AY.9.1	0.000084
N	179	G179S	Ggc	Agc	1	1	AY.99.1	0.001553
N	179	G179S	Ggc	Agc	1	1	B	0.000128
N	179	G179S	Ggc	Agc	1	1	B.1.1.174	0.003378
N	179	G179S	Ggc	Agc	1	1	B.1.1.290	0.018182
N	179	G179S	Ggc	Agc	1	1	B.1.1.306	0.000438
N	179	G179S	Ggc	Agc	1	1	B.1.1.318	0.000302
N	179	G179S	Ggc	Agc	1	1	B.1.1.33	0.000421
N	179	G179S	Ggc	Agc	1	1	B.1.1.44	0.00241
N	179	G179S	Ggc	Agc	1	1	B.1.177.86	0.000183
N	179	G179S	Ggc	Agc	1	1	B.1.189	0.004292
N	179	G179S	Ggc	Agc	1	1	B.1.243	0.00007
N	179	G179S	Ggc	Agc	1	1	B.1.258	0.000067
N	179	G179S	Ggc	Agc	1	1	B.1.311	0.000275
N	179	G179S	Ggc	Agc	1	1	B.1.36.17	0.000494
N	179	G179S	Ggc	Agc	1	1	B.1.36.36	0.000602
N	179	G179S	Ggc	Agc	1	1	B.1.399	0.001934
N	179	G179S	Ggc	Agc	1	1	B.1.466.2	0.000391
N	179	G179S	Ggc	Agc	1	1	B.1.474	0.001901
N	179	G179S	Ggc	Agc	1	1	B.1.523	0.002451
N	179	G179S	Ggc	Agc	1	1	B.1.575	0.000303
N	179	G179S	Ggc	Agc	1	1	B.1.617.1	0.000129
N	179	G179S	Ggc	Agc	1	1	B.1.639	0.021739
N	179	G179S	Ggc	Agc	1	1	B.50	0.111111
N	179	G179S	Ggc	Agc	1	1	P.1.17	0.000162
N	179	G179S	Ggc	Agc	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.