CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 175 | G175G | syn | ggG | ggT | 4326 | 2907 | 0.671983 | 28796-28798 | |
N | 175 | G175G | syn | ggG | ggA | 4326 | 1413 | 0.32663 | 28796-28798 | |
N | 175 | G175G | syn | ggG | ggC | 4326 | 6 | 0.00138696 | 28796-28798 |
Details of the mutation G175G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 175 | G175G | ggG | ggT | 2907 | 4326 | All | 0.000556 |
N | 175 | G175G | ggG | ggA | 1413 | 4326 | All | 0.00027 |
N | 175 | G175G | ggG | ggC | 6 | 4326 | All | 0.000001 |
N | 175 | G175G | ggG | ggT | 2169 | 2170 | AY.5 | 0.044788 |
N | 175 | G175G | ggG | ggA | 1 | 2170 | AY.5 | 0.000021 |
N | 175 | G175G | ggG | ggA | 744 | 818 | B.1.1.7 | 0.000666 |
N | 175 | G175G | ggG | ggT | 73 | 818 | B.1.1.7 | 0.000065 |
N | 175 | G175G | ggG | ggC | 1 | 818 | B.1.1.7 | 0.000001 |
N | 175 | G175G | ggG | ggA | 132 | 188 | AY.4 | 0.000205 |
N | 175 | G175G | ggG | ggT | 56 | 188 | AY.4 | 0.000087 |
N | 175 | G175G | ggG | ggT | 71 | 98 | B.1.617.2 | 0.000267 |
N | 175 | G175G | ggG | ggA | 27 | 98 | B.1.617.2 | 0.000102 |
N | 175 | G175G | ggG | ggT | 71 | 71 | AY.5.3 | 0.023954 |
N | 175 | G175G | ggG | ggA | 52 | 60 | AY.103 | 0.000323 |
N | 175 | G175G | ggG | ggT | 8 | 60 | AY.103 | 0.00005 |
N | 175 | G175G | ggG | ggT | 59 | 60 | AY.29 | 0.000931 |
N | 175 | G175G | ggG | ggA | 1 | 60 | AY.29 | 0.000016 |
N | 175 | G175G | ggG | ggA | 58 | 58 | B.1.258.20 | 0.920635 |
N | 175 | G175G | ggG | ggA | 52 | 52 | B.1.599 | 0.189781 |
N | 175 | G175G | ggG | ggT | 43 | 49 | AY.46 | 0.004475 |
N | 175 | G175G | ggG | ggA | 6 | 49 | AY.46 | 0.000624 |
N | 175 | G175G | ggG | ggT | 46 | 46 | AY.108 | 0.050717 |
N | 175 | G175G | ggG | ggT | 29 | 45 | B.1 | 0.000266 |
N | 175 | G175G | ggG | ggA | 13 | 45 | B.1 | 0.000119 |
N | 175 | G175G | ggG | ggC | 3 | 45 | B.1 | 0.000027 |
N | 175 | G175G | ggG | ggA | 41 | 44 | AY.26 | 0.001161 |
N | 175 | G175G | ggG | ggT | 3 | 44 | AY.26 | 0.000085 |
N | 175 | G175G | ggG | ggA | 27 | 41 | AY.44 | 0.000164 |
N | 175 | G175G | ggG | ggT | 14 | 41 | AY.44 | 0.000085 |
N | 175 | G175G | ggG | ggT | 27 | 37 | B.1.2 | 0.000238 |
N | 175 | G175G | ggG | ggA | 10 | 37 | B.1.2 | 0.000088 |
N | 175 | G175G | ggG | ggT | 32 | 32 | P.1.14 | 0.00153 |
N | 175 | G175G | ggG | ggA | 23 | 29 | AY.25 | 0.000138 |
N | 175 | G175G | ggG | ggT | 6 | 29 | AY.25 | 0.000036 |
N | 175 | G175G | ggG | ggA | 21 | 29 | AY.3 | 0.000209 |
N | 175 | G175G | ggG | ggT | 8 | 29 | AY.3 | 0.00008 |
N | 175 | G175G | ggG | ggT | 22 | 22 | B.1.1.170 | 0.027431 |
N | 175 | G175G | ggG | ggT | 12 | 21 | B.1.427 | 0.000606 |
N | 175 | G175G | ggG | ggA | 9 | 21 | B.1.427 | 0.000454 |
N | 175 | G175G | ggG | ggT | 13 | 20 | AY.43 | 0.000058 |
N | 175 | G175G | ggG | ggA | 7 | 20 | AY.43 | 0.000031 |
N | 175 | G175G | ggG | ggT | 13 | 20 | B.1.177 | 0.000171 |
N | 175 | G175G | ggG | ggA | 7 | 20 | B.1.177 | 0.000092 |
N | 175 | G175G | ggG | ggA | 11 | 19 | AY.47 | 0.000342 |
N | 175 | G175G | ggG | ggT | 8 | 19 | AY.47 | 0.000249 |
N | 175 | G175G | ggG | ggT | 17 | 17 | AY.120 | 0.000632 |
N | 175 | G175G | ggG | ggT | 17 | 17 | AY.98 | 0.001343 |
N | 175 | G175G | ggG | ggA | 9 | 16 | AY.102 | 0.000239 |
N | 175 | G175G | ggG | ggT | 7 | 16 | AY.102 | 0.000186 |
N | 175 | G175G | ggG | ggA | 13 | 16 | P.1 | 0.000205 |
N | 175 | G175G | ggG | ggT | 3 | 16 | P.1 | 0.000047 |
N | 175 | G175G | ggG | ggA | 10 | 11 | B.1.351 | 0.000297 |
N | 175 | G175G | ggG | ggT | 1 | 11 | B.1.351 | 0.00003 |
N | 175 | G175G | ggG | ggT | 8 | 9 | AY.42 | 0.000322 |
N | 175 | G175G | ggG | ggA | 1 | 9 | AY.42 | 0.00004 |
N | 175 | G175G | ggG | ggA | 8 | 9 | B.1.1 | 0.000145 |
N | 175 | G175G | ggG | ggC | 1 | 9 | B.1.1 | 0.000018 |
N | 175 | G175G | ggG | ggA | 7 | 9 | B.1.429 | 0.000165 |
N | 175 | G175G | ggG | ggT | 2 | 9 | B.1.429 | 0.000047 |
N | 175 | G175G | ggG | ggA | 8 | 8 | B.1.258.17 | 0.000832 |
N | 175 | G175G | ggG | ggA | 7 | 7 | AY.39.1 | 0.000277 |
N | 175 | G175G | ggG | ggA | 7 | 7 | B.1.1.414 | 1 |
N | 175 | G175G | ggG | ggA | 5 | 6 | B.1.160 | 0.000156 |
N | 175 | G175G | ggG | ggT | 1 | 6 | B.1.160 | 0.000031 |
N | 175 | G175G | ggG | ggT | 6 | 6 | B.1.507 | 0.067416 |
N | 175 | G175G | ggG | ggA | 6 | 6 | B.1.577 | 0.004124 |
N | 175 | G175G | ggG | ggT | 3 | 5 | AY.119 | 0.000106 |
N | 175 | G175G | ggG | ggA | 2 | 5 | AY.119 | 0.000071 |
N | 175 | G175G | ggG | ggA | 4 | 5 | AY.20 | 0.000155 |
N | 175 | G175G | ggG | ggT | 1 | 5 | AY.20 | 0.000039 |
N | 175 | G175G | ggG | ggT | 3 | 5 | AY.39 | 0.000074 |
N | 175 | G175G | ggG | ggA | 2 | 5 | AY.39 | 0.000049 |
N | 175 | G175G | ggG | ggA | 4 | 5 | B.1.526 | 0.000094 |
N | 175 | G175G | ggG | ggT | 1 | 5 | B.1.526 | 0.000024 |
N | 175 | G175G | ggG | ggA | 3 | 5 | C.37 | 0.000348 |
N | 175 | G175G | ggG | ggT | 2 | 5 | C.37 | 0.000232 |
N | 175 | G175G | ggG | ggA | 4 | 4 | AY.48 | 0.00186 |
N | 175 | G175G | ggG | ggT | 4 | 4 | AY.54 | 0.000381 |
N | 175 | G175G | ggG | ggA | 4 | 4 | AY.75 | 0.000224 |
N | 175 | G175G | ggG | ggA | 4 | 4 | B.1.36.31 | 0.007005 |
N | 175 | G175G | ggG | ggA | 4 | 4 | B.1.400 | 0.001716 |
N | 175 | G175G | ggG | ggA | 3 | 4 | B.1.621 | 0.000266 |
N | 175 | G175G | ggG | ggT | 1 | 4 | B.1.621 | 0.000089 |
N | 175 | G175G | ggG | ggA | 2 | 3 | AY.117 | 0.000169 |
N | 175 | G175G | ggG | ggC | 1 | 3 | AY.117 | 0.000085 |
N | 175 | G175G | ggG | ggT | 3 | 3 | AY.23 | 0.000209 |
N | 175 | G175G | ggG | ggA | 3 | 3 | AY.34 | 0.000291 |
N | 175 | G175G | ggG | ggT | 2 | 3 | AY.4.2 | 0.000043 |
N | 175 | G175G | ggG | ggA | 1 | 3 | AY.4.2 | 0.000022 |
N | 175 | G175G | ggG | ggT | 3 | 3 | AY.45 | 0.000365 |
N | 175 | G175G | ggG | ggT | 3 | 3 | AY.69 | 0.00056 |
N | 175 | G175G | ggG | ggT | 3 | 3 | AY.9 | 0.000203 |
N | 175 | G175G | ggG | ggA | 3 | 3 | B.1.1.337 | 0.010791 |
N | 175 | G175G | ggG | ggT | 2 | 3 | B.1.221 | 0.000142 |
N | 175 | G175G | ggG | ggA | 1 | 3 | B.1.221 | 0.000071 |
N | 175 | G175G | ggG | ggA | 3 | 3 | C.35 | 0.002322 |
N | 175 | G175G | ggG | ggA | 3 | 3 | P.2 | 0.00056 |
N | 175 | G175G | ggG | ggT | 2 | 2 | AE.1 | 0.022727 |
N | 175 | G175G | ggG | ggA | 2 | 2 | AY.113 | 0.000285 |
N | 175 | G175G | ggG | ggT | 2 | 2 | AY.121 | 0.000271 |
N | 175 | G175G | ggG | ggT | 2 | 2 | AY.33 | 0.000134 |
N | 175 | G175G | ggG | ggT | 2 | 2 | AY.73 | 0.001331 |
N | 175 | G175G | ggG | ggA | 2 | 2 | B.1.1.48 | 0.005747 |
N | 175 | G175G | ggG | ggT | 2 | 2 | B.1.177.73 | 0.001133 |
N | 175 | G175G | ggG | ggA | 2 | 2 | B.1.36 | 0.000292 |
N | 175 | G175G | ggG | ggA | 1 | 2 | D.2 | 0.000075 |
N | 175 | G175G | ggG | ggT | 1 | 2 | D.2 | 0.000075 |
N | 175 | G175G | ggG | ggT | 1 | 1 | A | 0.000387 |
N | 175 | G175G | ggG | ggA | 1 | 1 | A.2.5 | 0.000499 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.100 | 0.000046 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.12 | 0.000316 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.34.1 | 0.00051 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.36 | 0.000148 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.4.3 | 0.000842 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.46.4 | 0.000165 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.46.5 | 0.000198 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.46.6 | 0.000072 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.5.4 | 0.000277 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.52 | 0.000814 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.59 | 0.00053 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.6 | 0.000041 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.61 | 0.000105 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.67 | 0.000464 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.70 | 0.000209 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.84 | 0.000437 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.88 | 0.000884 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.9.2 | 0.000037 |
N | 175 | G175G | ggG | ggT | 1 | 1 | AY.93 | 0.000273 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.99.1 | 0.001553 |
N | 175 | G175G | ggG | ggA | 1 | 1 | AY.99.2 | 0.000092 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B | 0.000128 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.214 | 0.000055 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.222 | 0.000204 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.1.25 | 0.000569 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.263 | 0.001558 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.28 | 0.000311 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.311 | 0.000358 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.1.413 | 0.006897 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.1.519 | 0.00004 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.162 | 0.005025 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.177.12 | 0.000152 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.235 | 0.002519 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.239 | 0.001221 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.240 | 0.000216 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.258 | 0.000067 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.346 | 0.001311 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.356 | 0.001727 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.36.18 | 0.00042 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.36.29 | 0.000517 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.367 | 0.000792 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.369 | 0.000285 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.438.1 | 0.000107 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.462 | 0.007246 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.509 | 0.000866 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.525 | 0.000113 |
N | 175 | G175G | ggG | ggT | 1 | 1 | B.1.582 | 0.000491 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.587 | 0.001898 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.620 | 0.000946 |
N | 175 | G175G | ggG | ggA | 1 | 1 | B.1.628 | 0.000352 |
N | 175 | G175G | ggG | ggA | 1 | 1 | Q.7 | 0.001111 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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