CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = G164R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	164	G164R		nonsyn	Gga	Aga	677	529	0.781388	28763-28765
N	164	G164R		nonsyn	Gga	Cga	677	111	0.163959	28763-28765
N	164	G164R		nonsyn	GgA	CgT	677	18	0.0265879	28763-28765
N	164	G164R		nonsyn	GgA	CgC	677	8	0.0118168	28763-28765
N	164	G164R		nonsyn	GgA	CgG	677	7	0.0103397	28763-28765
N	164	G164R		nonsyn	GgA	AgG	677	4	0.00590842	28763-28765

Details of the mutation G164R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	164	G164R	Gga	Aga	529	677	All	0.000101
N	164	G164R	Gga	Cga	111	677	All	0.000021
N	164	G164R	GgA	CgT	18	677	All	0.000003
N	164	G164R	GgA	CgC	8	677	All	0.000002
N	164	G164R	GgA	CgG	7	677	All	0.000001
N	164	G164R	GgA	AgG	4	677	All	0.000001
N	164	G164R	Gga	Aga	152	153	B.1.617.2	0.000572
N	164	G164R	Gga	Cga	1	153	B.1.617.2	0.000004
N	164	G164R	Gga	Aga	115	117	AY.4	0.000179
N	164	G164R	Gga	Cga	2	117	AY.4	0.000003
N	164	G164R	Gga	Cga	27	69	B.1	0.000247
N	164	G164R	Gga	Aga	25	69	B.1	0.000229
N	164	G164R	GgA	CgT	9	69	B.1	0.000082
N	164	G164R	GgA	CgC	3	69	B.1	0.000027
N	164	G164R	GgA	AgG	3	69	B.1	0.000027
N	164	G164R	GgA	CgG	2	69	B.1	0.000018
N	164	G164R	Gga	Aga	50	50	B.1.591	0.531915
N	164	G164R	Gga	Aga	38	38	B.1.595.1	0.222222
N	164	G164R	Gga	Cga	9	25	B.1.177	0.000119
N	164	G164R	Gga	Aga	8	25	B.1.177	0.000105
N	164	G164R	GgA	CgT	3	25	B.1.177	0.00004
N	164	G164R	GgA	CgC	2	25	B.1.177	0.000026
N	164	G164R	GgA	CgG	2	25	B.1.177	0.000026
N	164	G164R	GgA	AgG	1	25	B.1.177	0.000013
N	164	G164R	Gga	Cga	18	20	AY.44	0.00011
N	164	G164R	Gga	Aga	2	20	AY.44	0.000012
N	164	G164R	Gga	Aga	12	20	B.1.1	0.000218
N	164	G164R	Gga	Cga	4	20	B.1.1	0.000073
N	164	G164R	GgA	CgC	2	20	B.1.1	0.000036
N	164	G164R	GgA	CgT	2	20	B.1.1	0.000036
N	164	G164R	Gga	Aga	9	11	B.1.177.86	0.001651
N	164	G164R	Gga	Cga	1	11	B.1.177.86	0.000183
N	164	G164R	GgA	CgC	1	11	B.1.177.86	0.000183
N	164	G164R	Gga	Aga	10	10	A	0.00387
N	164	G164R	Gga	Aga	9	10	B.1.1.7	0.000008
N	164	G164R	Gga	Cga	1	10	B.1.1.7	0.000001
N	164	G164R	Gga	Aga	4	9	B.1.2	0.000035
N	164	G164R	Gga	Cga	3	9	B.1.2	0.000026
N	164	G164R	GgA	CgG	1	9	B.1.2	0.000009
N	164	G164R	GgA	CgT	1	9	B.1.2	0.000009
N	164	G164R	Gga	Aga	8	8	AY.102	0.000212
N	164	G164R	Gga	Aga	8	8	AY.23.1	0.003339
N	164	G164R	Gga	Aga	8	8	B.1.595	0.002088
N	164	G164R	Gga	Cga	4	7	B.1.160	0.000125
N	164	G164R	GgA	CgG	1	7	B.1.160	0.000031
N	164	G164R	Gga	Aga	1	7	B.1.160	0.000031
N	164	G164R	GgA	CgT	1	7	B.1.160	0.000031
N	164	G164R	Gga	Aga	4	6	AY.43	0.000018
N	164	G164R	Gga	Cga	2	6	AY.43	0.000009
N	164	G164R	Gga	Aga	5	5	AY.13	0.000805
N	164	G164R	Gga	Cga	4	5	AY.3	0.00004
N	164	G164R	Gga	Aga	1	5	AY.3	0.00001
N	164	G164R	Gga	Aga	3	5	AY.39	0.000074
N	164	G164R	Gga	Cga	2	5	AY.39	0.000049
N	164	G164R	Gga	Cga	2	4	AY.5	0.000041
N	164	G164R	Gga	Aga	2	4	AY.5	0.000041
N	164	G164R	Gga	Aga	4	4	B.1.36	0.000584
N	164	G164R	Gga	Aga	4	4	B.1.509	0.003463
N	164	G164R	Gga	Aga	4	4	B.1.617.1	0.000516
N	164	G164R	Gga	Aga	3	3	AY.25	0.000018
N	164	G164R	Gga	Aga	3	3	AY.42	0.000121
N	164	G164R	Gga	Cga	2	3	B.1.1.385	0.008929
N	164	G164R	Gga	Aga	1	3	B.1.1.385	0.004464
N	164	G164R	Gga	Cga	3	3	B.1.177.44	0.001557
N	164	G164R	Gga	Aga	2	3	B.1.221	0.000142
N	164	G164R	Gga	Cga	1	3	B.1.221	0.000071
N	164	G164R	Gga	Cga	2	3	B.1.258	0.000133
N	164	G164R	Gga	Aga	1	3	B.1.258	0.000067
N	164	G164R	Gga	Aga	1	3	B.1.525	0.000113
N	164	G164R	GgA	CgT	1	3	B.1.525	0.000113
N	164	G164R	Gga	Cga	1	3	B.1.525	0.000113
N	164	G164R	Gga	Aga	2	2	AY.103	0.000012
N	164	G164R	Gga	Aga	1	2	AY.23	0.00007
N	164	G164R	Gga	Cga	1	2	AY.23	0.00007
N	164	G164R	Gga	Aga	2	2	AY.24	0.000862
N	164	G164R	Gga	Aga	2	2	AY.47	0.000062
N	164	G164R	Gga	Aga	2	2	AY.5.4	0.000553
N	164	G164R	Gga	Aga	2	2	AY.59	0.001059
N	164	G164R	GgA	CgT	1	2	B.1.1.515	0.02
N	164	G164R	Gga	Cga	1	2	B.1.1.515	0.02
N	164	G164R	Gga	Cga	2	2	B.1.110.3	0.001437
N	164	G164R	Gga	Aga	2	2	B.1.499	0.002101
N	164	G164R	Gga	Cga	1	2	B.1.609	0.000479
N	164	G164R	GgA	CgG	1	2	B.1.609	0.000479
N	164	G164R	Gga	Cga	2	2	P.1	0.000032
N	164	G164R	Gga	Aga	2	2	P.3	0.00319
N	164	G164R	Gga	Cga	1	1	AY.116.1	0.000311
N	164	G164R	Gga	Aga	1	1	AY.20	0.000039
N	164	G164R	Gga	Aga	1	1	AY.5.3	0.000337
N	164	G164R	Gga	Aga	1	1	AY.73	0.000665
N	164	G164R	Gga	Aga	1	1	AY.98	0.000079
N	164	G164R	Gga	Aga	1	1	B.1.1.135	0.004695
N	164	G164R	Gga	Cga	1	1	B.1.1.170	0.001247
N	164	G164R	Gga	Aga	1	1	B.1.1.301	0.001179
N	164	G164R	Gga	Cga	1	1	B.1.1.33	0.000421
N	164	G164R	Gga	Cga	1	1	B.1.1.372	0.000689
N	164	G164R	Gga	Aga	1	1	B.1.1.39	0.00051
N	164	G164R	Gga	Cga	1	1	B.1.1.521	0.005348
N	164	G164R	Gga	Aga	1	1	B.1.177.7	0.000165
N	164	G164R	Gga	Aga	1	1	B.1.177.81	0.000189
N	164	G164R	Gga	Aga	1	1	B.1.232	0.000537
N	164	G164R	Gga	Cga	1	1	B.1.258.17	0.000104
N	164	G164R	Gga	Cga	1	1	B.1.284	0.013158
N	164	G164R	Gga	Cga	1	1	B.1.311	0.000275
N	164	G164R	Gga	Aga	1	1	B.1.351	0.00003
N	164	G164R	Gga	Aga	1	1	B.1.372	0.010989
N	164	G164R	Gga	Cga	1	1	B.1.389	0.001002
N	164	G164R	Gga	Aga	1	1	B.1.427	0.00005
N	164	G164R	Gga	Aga	1	1	B.1.438.1	0.000107
N	164	G164R	Gga	Cga	1	1	B.1.497	0.000315
N	164	G164R	Gga	Cga	1	1	B.1.526	0.000024
N	164	G164R	Gga	Aga	1	1	B.1.576	0.000907
N	164	G164R	Gga	Cga	1	1	B.1.619.1	0.000641
N	164	G164R	Gga	Cga	1	1	C.35	0.000774
N	164	G164R	Gga	Cga	1	1	D.2	0.000075
N	164	G164R	Gga	Cga	1	1	K.1	0.02381
N	164	G164R	Gga	Aga	1	1	P.6	0.003145
N	164	G164R	Gga	Aga	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.