CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 367 | E367E | syn | gaG | gaA | 1974 | 1974 | 1 | 29372-29374 |
Details of the mutation E367E within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 367 | E367E | gaG | gaA | 1974 | 1974 | All | 0.000378 |
N | 367 | E367E | gaG | gaA | 421 | 421 | B.1.2 | 0.003707 |
N | 367 | E367E | gaG | gaA | 237 | 237 | B.1.1.7 | 0.000212 |
N | 367 | E367E | gaG | gaA | 222 | 222 | AY.9.1 | 0.018587 |
N | 367 | E367E | gaG | gaA | 146 | 146 | P.1 | 0.0023 |
N | 367 | E367E | gaG | gaA | 92 | 92 | AY.4 | 0.000143 |
N | 367 | E367E | gaG | gaA | 62 | 62 | B.1.617.2 | 0.000233 |
N | 367 | E367E | gaG | gaA | 60 | 60 | B.4.6 | 1 |
N | 367 | E367E | gaG | gaA | 58 | 58 | AY.103 | 0.00036 |
N | 367 | E367E | gaG | gaA | 55 | 55 | AY.43 | 0.000244 |
N | 367 | E367E | gaG | gaA | 47 | 47 | AY.44 | 0.000286 |
N | 367 | E367E | gaG | gaA | 42 | 42 | AY.100 | 0.001932 |
N | 367 | E367E | gaG | gaA | 40 | 40 | AY.3 | 0.000398 |
N | 367 | E367E | gaG | gaA | 36 | 36 | B.1 | 0.00033 |
N | 367 | E367E | gaG | gaA | 34 | 34 | AY.25 | 0.000205 |
N | 367 | E367E | gaG | gaA | 33 | 33 | B.1.1.377 | 0.04558 |
N | 367 | E367E | gaG | gaA | 25 | 25 | AY.39 | 0.000618 |
N | 367 | E367E | gaG | gaA | 21 | 21 | B.1.1.284 | 0.002255 |
N | 367 | E367E | gaG | gaA | 19 | 19 | B.1.221 | 0.00135 |
N | 367 | E367E | gaG | gaA | 15 | 15 | B.1.177 | 0.000198 |
N | 367 | E367E | gaG | gaA | 14 | 14 | AY.119 | 0.000494 |
N | 367 | E367E | gaG | gaA | 14 | 14 | P.1.14 | 0.000669 |
N | 367 | E367E | gaG | gaA | 12 | 12 | B.1.1 | 0.000218 |
N | 367 | E367E | gaG | gaA | 12 | 12 | B.1.438.1 | 0.001287 |
N | 367 | E367E | gaG | gaA | 12 | 12 | B.1.596 | 0.001046 |
N | 367 | E367E | gaG | gaA | 11 | 11 | AY.26 | 0.000311 |
N | 367 | E367E | gaG | gaA | 11 | 11 | B.1.526 | 0.000259 |
N | 367 | E367E | gaG | gaA | 10 | 10 | B.1.1.519 | 0.000397 |
N | 367 | E367E | gaG | gaA | 9 | 9 | AY.117 | 0.000761 |
N | 367 | E367E | gaG | gaA | 9 | 9 | B.1.177.43 | 0.013294 |
N | 367 | E367E | gaG | gaA | 9 | 9 | B.1.258 | 0.000599 |
N | 367 | E367E | gaG | gaA | 9 | 9 | B.1.351 | 0.000268 |
N | 367 | E367E | gaG | gaA | 7 | 7 | AY.102 | 0.000186 |
N | 367 | E367E | gaG | gaA | 7 | 7 | C.37 | 0.000812 |
N | 367 | E367E | gaG | gaA | 6 | 6 | AY.5 | 0.000124 |
N | 367 | E367E | gaG | gaA | 6 | 6 | B.1.1.218 | 0.046154 |
N | 367 | E367E | gaG | gaA | 6 | 6 | B.1.1.37 | 0.001157 |
N | 367 | E367E | gaG | gaA | 6 | 6 | B.4 | 0.013245 |
N | 367 | E367E | gaG | gaA | 5 | 5 | AY.46.4 | 0.000823 |
N | 367 | E367E | gaG | gaA | 5 | 5 | B.1.564 | 0.002129 |
N | 367 | E367E | gaG | gaA | 4 | 4 | AY.98.1 | 0.000194 |
N | 367 | E367E | gaG | gaA | 4 | 4 | B.1.1.25 | 0.002274 |
N | 367 | E367E | gaG | gaA | 4 | 4 | B.1.258.22 | 0.010667 |
N | 367 | E367E | gaG | gaA | 4 | 4 | B.1.470 | 0.005618 |
N | 367 | E367E | gaG | gaA | 3 | 3 | AY.13 | 0.000483 |
N | 367 | E367E | gaG | gaA | 3 | 3 | AY.3.1 | 0.000256 |
N | 367 | E367E | gaG | gaA | 3 | 3 | AY.91 | 0.002191 |
N | 367 | E367E | gaG | gaA | 3 | 3 | AZ.2 | 0.002463 |
N | 367 | E367E | gaG | gaA | 3 | 3 | B.1.234 | 0.000396 |
N | 367 | E367E | gaG | gaA | 3 | 3 | B.1.621 | 0.000266 |
N | 367 | E367E | gaG | gaA | 3 | 3 | P.1.7 | 0.000958 |
N | 367 | E367E | gaG | gaA | 2 | 2 | 0.111111 | |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.11 | 0.002677 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.120 | 0.000074 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.42 | 0.00008 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.46.6 | 0.000144 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.47 | 0.000062 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.61 | 0.00021 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.74 | 0.000231 |
N | 367 | E367E | gaG | gaA | 2 | 2 | AY.75 | 0.000112 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.1.214 | 0.000111 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.1.28 | 0.000622 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.1.39 | 0.001019 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.1.398 | 0.006452 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.1.419 | 0.014815 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.258.17 | 0.000208 |
N | 367 | E367E | gaG | gaA | 2 | 2 | B.1.36 | 0.000292 |
N | 367 | E367E | gaG | gaA | 2 | 2 | P.1.2 | 0.002312 |
N | 367 | E367E | gaG | gaA | 2 | 2 | Q.1 | 0.000253 |
N | 367 | E367E | gaG | gaA | 1 | 1 | A.2 | 0.000662 |
N | 367 | E367E | gaG | gaA | 1 | 1 | A.2.4 | 0.003367 |
N | 367 | E367E | gaG | gaA | 1 | 1 | A.2.5 | 0.000499 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.106 | 0.000335 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.110 | 0.000113 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.113 | 0.000142 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.121 | 0.000135 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.14 | 0.000088 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.23 | 0.00007 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.23.1 | 0.000417 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.27 | 0.000065 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.28 | 0.00189 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.29 | 0.000016 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.38 | 0.000499 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.39.1 | 0.00004 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.4.2.1 | 0.000149 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.4.3 | 0.000842 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.45 | 0.000122 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.5.3 | 0.000337 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.54 | 0.000095 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.59 | 0.00053 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.73 | 0.000665 |
N | 367 | E367E | gaG | gaA | 1 | 1 | AY.9.2 | 0.000037 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B | 0.000128 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.1 | 0.000327 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.134 | 0.011364 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.220 | 0.001859 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.241 | 0.00207 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.277 | 0.000759 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.289 | 0.002083 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.33 | 0.000421 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.420 | 0.001006 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.434 | 0.000349 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.459 | 0.015385 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.486 | 0.001577 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.50 | 0.000679 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.1.523 | 0.001563 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.127 | 0.002198 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.177.63 | 0.002703 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.177.81 | 0.000189 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.240 | 0.000216 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.258.19 | 0.007092 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.351.3 | 0.000876 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.356 | 0.001727 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.36.29 | 0.000517 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.36.31 | 0.001751 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.427 | 0.00005 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.451 | 0.008197 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.533 | 0.009615 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.599 | 0.00365 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.600 | 0.005848 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.1.623 | 0.000536 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.11 | 0.005128 |
N | 367 | E367E | gaG | gaA | 1 | 1 | B.40 | 0.000364 |
N | 367 | E367E | gaG | gaA | 1 | 1 | C.16 | 0.00106 |
N | 367 | E367E | gaG | gaA | 1 | 1 | P.1.17 | 0.000162 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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