CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = D371D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	371	D371D		syn	gaC	gaT	18057	18057	1	29384-29386

Details of the mutation D371D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	371	D371D	gaC	gaT	18057	18057	All	0.003454
N	371	D371D	gaC	gaT	6496	6496	B.1.177.12	0.985437
N	371	D371D	gaC	gaT	4550	4550	B.1.177	0.059913
N	371	D371D	gaC	gaT	1730	1730	B.1.177.44	0.897769
N	371	D371D	gaC	gaT	1364	1364	B.1.177.35	0.94264
N	371	D371D	gaC	gaT	1074	1074	B.1.177.42	0.960644
N	371	D371D	gaC	gaT	618	618	B.1.177.43	0.912851
N	371	D371D	gaC	gaT	391	391	B.1.177.41	0.9775
N	371	D371D	gaC	gaT	192	192	B.1.1.7	0.000172
N	371	D371D	gaC	gaT	181	181	B.1.177.85	0.983696
N	371	D371D	gaC	gaT	178	178	AY.5	0.003676
N	371	D371D	gaC	gaT	178	178	B.1.177.40	0.917526
N	371	D371D	gaC	gaT	114	114	B.1	0.001044
N	371	D371D	gaC	gaT	92	92	B.1.177.38	0.958333
N	371	D371D	gaC	gaT	74	74	AY.103	0.000459
N	371	D371D	gaC	gaT	62	62	B.1.177.39	0.953846
N	371	D371D	gaC	gaT	60	60	B.1.177.36	0.967742
N	371	D371D	gaC	gaT	48	48	B.1.160	0.001497
N	371	D371D	gaC	gaT	46	46	B.1.160.30	0.136905
N	371	D371D	gaC	gaT	44	44	AY.4	0.000068
N	371	D371D	gaC	gaT	41	41	B.1.221	0.002912
N	371	D371D	gaC	gaT	39	39	AY.25	0.000235
N	371	D371D	gaC	gaT	37	37	B.1.617.2	0.000139
N	371	D371D	gaC	gaT	33	33	B.1.177.37	0.891892
N	371	D371D	gaC	gaT	22	22	B.1.36	0.00321
N	371	D371D	gaC	gaT	21	21	AY.43	0.000093
N	371	D371D	gaC	gaT	19	19	AY.44	0.000116
N	371	D371D	gaC	gaT	19	19	C.38	0.153226
N	371	D371D	gaC	gaT	16	16	AY.53	0.0046
N	371	D371D	gaC	gaT	14	14	B.1.240	0.003018
N	371	D371D	gaC	gaT	13	13	B.1.177.6	0.012695
N	371	D371D	gaC	gaT	12	12	B.1.1.39	0.006116
N	371	D371D	gaC	gaT	10	10	B.1.427	0.000505
N	371	D371D	gaC	gaT	9	9	B.1.416.1	0.014063
N	371	D371D	gaC	gaT	8	8	B.1.177.9	0.010652
N	371	D371D	gaC	gaT	8	8	B.1.2	0.00007
N	371	D371D	gaC	gaT	8	8	B.1.429	0.000188
N	371	D371D	gaC	gaT	7	7	AY.29	0.00011
N	371	D371D	gaC	gaT	7	7	AY.47	0.000218
N	371	D371D	gaC	gaT	7	7	B.1.1.100	0.28
N	371	D371D	gaC	gaT	7	7	B.1.1.432	0.008861
N	371	D371D	gaC	gaT	7	7	P.1	0.00011
N	371	D371D	gaC	gaT	6	6	AY.3	0.00006
N	371	D371D	gaC	gaT	6	6	B.1.1	0.000109
N	371	D371D	gaC	gaT	6	6	B.1.160.32	0.025751
N	371	D371D	gaC	gaT	6	6	B.1.177.31	0.068966
N	371	D371D	gaC	gaT	6	6	B.1.351	0.000178
N	371	D371D	gaC	gaT	5	5	B.1.1.216	0.004452
N	371	D371D	gaC	gaT	4	4	AY.102	0.000106
N	371	D371D	gaC	gaT	4	4	AY.39	0.000099
N	371	D371D	gaC	gaT	4	4	AY.39.1	0.000158
N	371	D371D	gaC	gaT	4	4	AY.46.4	0.000658
N	371	D371D	gaC	gaT	4	4	B.1.1.25	0.002274
N	371	D371D	gaC	gaT	4	4	B.1.177.73	0.002265
N	371	D371D	gaC	gaT	4	4	B.1.466.2	0.001565
N	371	D371D	gaC	gaT	4	4	P.1.6	0.007782
N	371	D371D	gaC	gaT	3	3	AY.114	0.000693
N	371	D371D	gaC	gaT	3	3	AY.27	0.000194
N	371	D371D	gaC	gaT	3	3	AY.69	0.00056
N	371	D371D	gaC	gaT	3	3	AY.7	0.000588
N	371	D371D	gaC	gaT	3	3	B.1.177.21	0.000229
N	371	D371D	gaC	gaT	3	3	B.1.177.45	0.001144
N	371	D371D	gaC	gaT	3	3	B.1.177.86	0.00055
N	371	D371D	gaC	gaT	3	3	B.1.258	0.0002
N	371	D371D	gaC	gaT	3	3	P.1.14	0.000143
N	371	D371D	gaC	gaT	2	2	AY.118	0.000125
N	371	D371D	gaC	gaT	2	2	AY.16	0.000759
N	371	D371D	gaC	gaT	2	2	AY.23	0.000139
N	371	D371D	gaC	gaT	2	2	AY.26	0.000057
N	371	D371D	gaC	gaT	2	2	AY.37	0.000632
N	371	D371D	gaC	gaT	2	2	AY.4.2	0.000043
N	371	D371D	gaC	gaT	2	2	AY.67	0.000929
N	371	D371D	gaC	gaT	2	2	AY.79	0.002421
N	371	D371D	gaC	gaT	2	2	AY.80	0.002257
N	371	D371D	gaC	gaT	2	2	AY.9.2	0.000073
N	371	D371D	gaC	gaT	2	2	B	0.000256
N	371	D371D	gaC	gaT	2	2	B.1.1.372	0.001377
N	371	D371D	gaC	gaT	2	2	B.1.160.10	0.016129
N	371	D371D	gaC	gaT	2	2	B.1.177.24	0.002591
N	371	D371D	gaC	gaT	2	2	B.1.177.52	0.003515
N	371	D371D	gaC	gaT	2	2	B.1.177.57	0.000562
N	371	D371D	gaC	gaT	2	2	B.1.177.84	0.013333
N	371	D371D	gaC	gaT	2	2	B.1.243	0.000139
N	371	D371D	gaC	gaT	2	2	B.1.381	0.015625
N	371	D371D	gaC	gaT	2	2	B.1.497	0.00063
N	371	D371D	gaC	gaT	2	2	B.1.526	0.000047
N	371	D371D	gaC	gaT	2	2	C.37	0.000232
N	371	D371D	gaC	gaT	2	2	P.1.15	0.000465
N	371	D371D	gaC	gaT	1	1	AN.1	0.02
N	371	D371D	gaC	gaT	1	1	AY.23.1	0.000417
N	371	D371D	gaC	gaT	1	1	AY.30	0.000396
N	371	D371D	gaC	gaT	1	1	AY.33	0.000067
N	371	D371D	gaC	gaT	1	1	AY.4.1	0.000737
N	371	D371D	gaC	gaT	1	1	AY.45	0.000122
N	371	D371D	gaC	gaT	1	1	AY.5.3	0.000337
N	371	D371D	gaC	gaT	1	1	AY.7.1	0.000113
N	371	D371D	gaC	gaT	1	1	AY.84	0.000437
N	371	D371D	gaC	gaT	1	1	AY.9	0.000068
N	371	D371D	gaC	gaT	1	1	AY.92	0.000287
N	371	D371D	gaC	gaT	1	1	AY.98	0.000079
N	371	D371D	gaC	gaT	1	1	AY.98.1	0.000048
N	371	D371D	gaC	gaT	1	1	AZ.2	0.000821
N	371	D371D	gaC	gaT	1	1	B.1.1.189	0.001513
N	371	D371D	gaC	gaT	1	1	B.1.1.269	0.001353
N	371	D371D	gaC	gaT	1	1	B.1.1.303	0.002762
N	371	D371D	gaC	gaT	1	1	B.1.1.306	0.000438
N	371	D371D	gaC	gaT	1	1	B.1.1.326	0.001761
N	371	D371D	gaC	gaT	1	1	B.1.1.389	0.006061
N	371	D371D	gaC	gaT	1	1	B.1.1.433	0.001425
N	371	D371D	gaC	gaT	1	1	B.1.1.434	0.000349
N	371	D371D	gaC	gaT	1	1	B.1.1.519	0.00004
N	371	D371D	gaC	gaT	1	1	B.1.1.521	0.005348
N	371	D371D	gaC	gaT	1	1	B.1.1.70	0.000341
N	371	D371D	gaC	gaT	1	1	B.1.1.71	0.006061
N	371	D371D	gaC	gaT	1	1	B.1.160.25	0.011111
N	371	D371D	gaC	gaT	1	1	B.1.177.17	0.000821
N	371	D371D	gaC	gaT	1	1	B.1.177.23	0.003236
N	371	D371D	gaC	gaT	1	1	B.1.177.32	0.00135
N	371	D371D	gaC	gaT	1	1	B.1.177.50	0.004695
N	371	D371D	gaC	gaT	1	1	B.1.177.65	0.000665
N	371	D371D	gaC	gaT	1	1	B.1.177.81	0.000189
N	371	D371D	gaC	gaT	1	1	B.1.177.83	0.001481
N	371	D371D	gaC	gaT	1	1	B.1.22	0.001318
N	371	D371D	gaC	gaT	1	1	B.1.222	0.001692
N	371	D371D	gaC	gaT	1	1	B.1.236	0.002053
N	371	D371D	gaC	gaT	1	1	B.1.258.11	0.000396
N	371	D371D	gaC	gaT	1	1	B.1.258.21	0.007752
N	371	D371D	gaC	gaT	1	1	B.1.260	0.003344
N	371	D371D	gaC	gaT	1	1	B.1.35	0.008475
N	371	D371D	gaC	gaT	1	1	B.1.36.22	0.001208
N	371	D371D	gaC	gaT	1	1	B.1.362	0.001541
N	371	D371D	gaC	gaT	1	1	B.1.375	0.00082
N	371	D371D	gaC	gaT	1	1	B.1.421	0.007463
N	371	D371D	gaC	gaT	1	1	B.1.462	0.007246
N	371	D371D	gaC	gaT	1	1	B.1.509	0.000866
N	371	D371D	gaC	gaT	1	1	B.1.525	0.000113
N	371	D371D	gaC	gaT	1	1	B.1.590	0.004545
N	371	D371D	gaC	gaT	1	1	B.1.595	0.000261
N	371	D371D	gaC	gaT	1	1	B.1.609	0.000479
N	371	D371D	gaC	gaT	1	1	B.1.617.1	0.000129
N	371	D371D	gaC	gaT	1	1	B.1.619.1	0.000641
N	371	D371D	gaC	gaT	1	1	B.1.621	0.000089
N	371	D371D	gaC	gaT	1	1	B.1.627	0.00202
N	371	D371D	gaC	gaT	1	1	B.1.628	0.000352
N	371	D371D	gaC	gaT	1	1	D.2	0.000075
N	371	D371D	gaC	gaT	1	1	P.1.12	0.000484
N	371	D371D	gaC	gaT	1	1	P.1.2	0.001156
N	371	D371D	gaC	gaT	1	1	Q.3	0.000145
N	371	D371D	gaC	gaT	1	1	Z.1	0.00289

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.