CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = D103Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	103	D103Y		nonsyn	Gat	Tat	3644	3643	0.999726	28580-28582
N	103	D103Y		nonsyn	GaT	TaC	3644	1	0.000274424	28580-28582

Details of the mutation D103Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	103	D103Y	Gat	Tat	3643	3644	All	0.000697
N	103	D103Y	GaT	TaC	1	3644	All	0
N	103	D103Y	Gat	Tat	2237	2237	B.1.1.369	0.998215
N	103	D103Y	Gat	Tat	239	239	B.1.160	0.007454
N	103	D103Y	Gat	Tat	141	141	B.1.429	0.003318
N	103	D103Y	Gat	Tat	101	101	B.1.243	0.007028
N	103	D103Y	Gat	Tat	90	90	AY.103	0.000559
N	103	D103Y	Gat	Tat	67	67	AY.4	0.000104
N	103	D103Y	Gat	Tat	62	62	B.1.1.366	0.984127
N	103	D103Y	Gat	Tat	59	59	B.1.1.7	0.000053
N	103	D103Y	Gat	Tat	59	59	B.1.617.2	0.000222
N	103	D103Y	Gat	Tat	49	49	AY.43	0.000217
N	103	D103Y	Gat	Tat	38	38	B.1	0.000348
N	103	D103Y	Gat	Tat	25	25	B.1.2	0.00022
N	103	D103Y	Gat	Tat	24	24	P.1	0.000378
N	103	D103Y	Gat	Tat	23	23	AY.44	0.00014
N	103	D103Y	Gat	Tat	16	16	AY.42	0.000644
N	103	D103Y	Gat	Tat	13	13	AY.75	0.000728
N	103	D103Y	Gat	Tat	13	13	B.1.234	0.001715
N	103	D103Y	Gat	Tat	12	12	B.1.177	0.000158
N	103	D103Y	Gat	Tat	12	12	B.1.36	0.001751
N	103	D103Y	Gat	Tat	10	11	B.1.1	0.000181
N	103	D103Y	GaT	TaC	1	11	B.1.1	0.000018
N	103	D103Y	Gat	Tat	10	10	B.1.1.519	0.000397
N	103	D103Y	Gat	Tat	10	10	B.1.427	0.000505
N	103	D103Y	Gat	Tat	9	9	AY.16	0.003417
N	103	D103Y	Gat	Tat	9	9	AY.25	0.000054
N	103	D103Y	Gat	Tat	9	9	AY.74	0.001041
N	103	D103Y	Gat	Tat	9	9	B.1.351	0.000268
N	103	D103Y	Gat	Tat	8	8	AY.119	0.000282
N	103	D103Y	Gat	Tat	8	8	AY.26	0.000226
N	103	D103Y	Gat	Tat	8	8	B.1.1.222	0.001632
N	103	D103Y	Gat	Tat	8	8	B.1.304	0.186047
N	103	D103Y	Gat	Tat	8	8	B.1.544	0.048193
N	103	D103Y	Gat	Tat	7	7	B.1.596	0.00061
N	103	D103Y	Gat	Tat	7	7	P.1.15	0.001626
N	103	D103Y	Gat	Tat	6	6	AY.3	0.00006
N	103	D103Y	Gat	Tat	6	6	AY.47	0.000187
N	103	D103Y	Gat	Tat	6	6	AY.5	0.000124
N	103	D103Y	Gat	Tat	6	6	AY.61	0.000629
N	103	D103Y	Gat	Tat	6	6	B.1.1.1	0.00196
N	103	D103Y	Gat	Tat	6	6	B.1.526	0.000141
N	103	D103Y	Gat	Tat	5	5	A.5	0.009615
N	103	D103Y	Gat	Tat	5	5	AY.29	0.000079
N	103	D103Y	Gat	Tat	5	5	AY.65	0.002665
N	103	D103Y	Gat	Tat	5	5	AY.98.1	0.000242
N	103	D103Y	Gat	Tat	5	5	B.1.1.284	0.000537
N	103	D103Y	Gat	Tat	5	5	B.1.623	0.002682
N	103	D103Y	Gat	Tat	4	4	AY.20	0.000155
N	103	D103Y	Gat	Tat	4	4	AY.39.1	0.000158
N	103	D103Y	Gat	Tat	4	4	B.1.1.216	0.003562
N	103	D103Y	Gat	Tat	4	4	B.1.398	0.011905
N	103	D103Y	Gat	Tat	4	4	B.1.621	0.000354
N	103	D103Y	Gat	Tat	4	4	D.2	0.0003
N	103	D103Y	Gat	Tat	3	3	AY.100	0.000138
N	103	D103Y	Gat	Tat	3	3	AY.102	0.00008
N	103	D103Y	Gat	Tat	3	3	AY.117	0.000254
N	103	D103Y	Gat	Tat	3	3	AY.4.2	0.000065
N	103	D103Y	Gat	Tat	3	3	B.1.1.28	0.000934
N	103	D103Y	Gat	Tat	3	3	B.1.1.311	0.001074
N	103	D103Y	Gat	Tat	3	3	B.1.192	0.027778
N	103	D103Y	Gat	Tat	3	3	B.1.36.29	0.001552
N	103	D103Y	Gat	Tat	3	3	B.1.369	0.000856
N	103	D103Y	Gat	Tat	3	3	B.1.468	0.017143
N	103	D103Y	Gat	Tat	3	3	B.1.595	0.000783
N	103	D103Y	Gat	Tat	3	3	B.1.617.1	0.000387
N	103	D103Y	Gat	Tat	3	3	B.41	0.024
N	103	D103Y	Gat	Tat	3	3	C.37	0.000348
N	103	D103Y	Gat	Tat	2	2	AY.13	0.000322
N	103	D103Y	Gat	Tat	2	2	AY.23	0.000139
N	103	D103Y	Gat	Tat	2	2	AY.30	0.000791
N	103	D103Y	Gat	Tat	2	2	AY.39	0.000049
N	103	D103Y	Gat	Tat	2	2	AY.62	0.000871
N	103	D103Y	Gat	Tat	2	2	AY.68	0.000547
N	103	D103Y	Gat	Tat	2	2	AY.71	0.00095
N	103	D103Y	Gat	Tat	2	2	AY.9	0.000135
N	103	D103Y	Gat	Tat	2	2	AY.9.1	0.000167
N	103	D103Y	Gat	Tat	2	2	AY.98	0.000158
N	103	D103Y	Gat	Tat	2	2	B.1.1.214	0.000111
N	103	D103Y	Gat	Tat	2	2	B.1.1.269	0.002706
N	103	D103Y	Gat	Tat	2	2	B.1.1.306	0.000877
N	103	D103Y	Gat	Tat	2	2	B.1.1.317	0.000823
N	103	D103Y	Gat	Tat	2	2	B.1.1.70	0.000682
N	103	D103Y	Gat	Tat	2	2	B.1.177.57	0.000562
N	103	D103Y	Gat	Tat	2	2	B.1.177.82	0.000955
N	103	D103Y	Gat	Tat	2	2	B.1.218	0.010309
N	103	D103Y	Gat	Tat	2	2	B.1.23	0.012121
N	103	D103Y	Gat	Tat	2	2	B.1.311	0.000549
N	103	D103Y	Gat	Tat	2	2	B.1.36.8	0.002
N	103	D103Y	Gat	Tat	2	2	B.1.466.2	0.000782
N	103	D103Y	Gat	Tat	2	2	P.1.17	0.000324
N	103	D103Y	Gat	Tat	2	2	Q.8	0.00033
N	103	D103Y	Gat	Tat	1	1	A	0.000387
N	103	D103Y	Gat	Tat	1	1	A.3	0.002096
N	103	D103Y	Gat	Tat	1	1	AY.105	0.000643
N	103	D103Y	Gat	Tat	1	1	AY.106	0.000335
N	103	D103Y	Gat	Tat	1	1	AY.113	0.000142
N	103	D103Y	Gat	Tat	1	1	AY.120	0.000037
N	103	D103Y	Gat	Tat	1	1	AY.120.2.1	0.000498
N	103	D103Y	Gat	Tat	1	1	AY.14	0.000088
N	103	D103Y	Gat	Tat	1	1	AY.3.1	0.000085
N	103	D103Y	Gat	Tat	1	1	AY.33	0.000067
N	103	D103Y	Gat	Tat	1	1	AY.36	0.000148
N	103	D103Y	Gat	Tat	1	1	AY.4.2.1	0.000149
N	103	D103Y	Gat	Tat	1	1	AY.4.4	0.000409
N	103	D103Y	Gat	Tat	1	1	AY.46	0.000104
N	103	D103Y	Gat	Tat	1	1	AY.46.6	0.000072
N	103	D103Y	Gat	Tat	1	1	AY.54	0.000095
N	103	D103Y	Gat	Tat	1	1	AY.6	0.000041
N	103	D103Y	Gat	Tat	1	1	AY.8	0.000606
N	103	D103Y	Gat	Tat	1	1	AY.84	0.000437
N	103	D103Y	Gat	Tat	1	1	AY.9.2	0.000037
N	103	D103Y	Gat	Tat	1	1	B	0.000128
N	103	D103Y	Gat	Tat	1	1	B.1.1.192	0.002309
N	103	D103Y	Gat	Tat	1	1	B.1.1.227	0.004348
N	103	D103Y	Gat	Tat	1	1	B.1.1.263	0.001558
N	103	D103Y	Gat	Tat	1	1	B.1.1.27	0.00565
N	103	D103Y	Gat	Tat	1	1	B.1.1.29	0.010309
N	103	D103Y	Gat	Tat	1	1	B.1.1.297	0.002237
N	103	D103Y	Gat	Tat	1	1	B.1.1.312	0.001912
N	103	D103Y	Gat	Tat	1	1	B.1.1.37	0.000193
N	103	D103Y	Gat	Tat	1	1	B.1.1.372	0.000689
N	103	D103Y	Gat	Tat	1	1	B.1.1.375	0.011905
N	103	D103Y	Gat	Tat	1	1	B.1.1.58	0.005376
N	103	D103Y	Gat	Tat	1	1	B.1.1.61	0.008772
N	103	D103Y	Gat	Tat	1	1	B.1.177.4	0.000211
N	103	D103Y	Gat	Tat	1	1	B.1.177.45	0.000381
N	103	D103Y	Gat	Tat	1	1	B.1.177.60	0.000218
N	103	D103Y	Gat	Tat	1	1	B.1.177.73	0.000566
N	103	D103Y	Gat	Tat	1	1	B.1.177.75	0.001041
N	103	D103Y	Gat	Tat	1	1	B.1.221	0.000071
N	103	D103Y	Gat	Tat	1	1	B.1.241	0.000812
N	103	D103Y	Gat	Tat	1	1	B.1.258	0.000067
N	103	D103Y	Gat	Tat	1	1	B.1.258.11	0.000396
N	103	D103Y	Gat	Tat	1	1	B.1.3	0.002618
N	103	D103Y	Gat	Tat	1	1	B.1.324	0.001605
N	103	D103Y	Gat	Tat	1	1	B.1.351.3	0.000876
N	103	D103Y	Gat	Tat	1	1	B.1.36.21	0.00216
N	103	D103Y	Gat	Tat	1	1	B.1.36.24	0.006173
N	103	D103Y	Gat	Tat	1	1	B.1.389	0.001002
N	103	D103Y	Gat	Tat	1	1	B.1.397	0.004854
N	103	D103Y	Gat	Tat	1	1	B.1.456	0.003268
N	103	D103Y	Gat	Tat	1	1	B.1.465	0.003802
N	103	D103Y	Gat	Tat	1	1	B.1.497	0.000315
N	103	D103Y	Gat	Tat	1	1	B.1.500	0.052632
N	103	D103Y	Gat	Tat	1	1	B.1.525	0.000113
N	103	D103Y	Gat	Tat	1	1	B.1.577	0.000687
N	103	D103Y	Gat	Tat	1	1	B.1.582	0.000491
N	103	D103Y	Gat	Tat	1	1	B.1.637	0.000073
N	103	D103Y	Gat	Tat	1	1	B.40	0.000364
N	103	D103Y	Gat	Tat	1	1	B.58	0.010204
N	103	D103Y	Gat	Tat	1	1	N.5	0.001767
N	103	D103Y	Gat	Tat	1	1	P.1.10	0.000269
N	103	D103Y	Gat	Tat	1	1	P.1.14	0.000048
N	103	D103Y	Gat	Tat	1	1	P.2	0.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.