CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 308 | A308S | nonsyn | Gcc | Tcc | 2835 | 2831 | 0.998589 | 29195-29197 | |
N | 308 | A308S | nonsyn | GcC | TcT | 2835 | 3 | 0.0010582 | 29195-29197 | |
N | 308 | A308S | nonsyn | GCc | AGc | 2835 | 1 | 0.000352734 | 29195-29197 |
Details of the mutation A308S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 308 | A308S | Gcc | Tcc | 2831 | 2835 | All | 0.000541 |
N | 308 | A308S | GcC | TcT | 3 | 2835 | All | 0.000001 |
N | 308 | A308S | GCc | AGc | 1 | 2835 | All | 0 |
N | 308 | A308S | Gcc | Tcc | 552 | 552 | B.1.1.7 | 0.000494 |
N | 308 | A308S | Gcc | Tcc | 392 | 392 | AY.4 | 0.00061 |
N | 308 | A308S | Gcc | Tcc | 258 | 258 | B.1.1.141 | 0.519115 |
N | 308 | A308S | Gcc | Tcc | 150 | 150 | B.1.2 | 0.001321 |
N | 308 | A308S | Gcc | Tcc | 115 | 115 | B.1.610 | 0.407801 |
N | 308 | A308S | Gcc | Tcc | 108 | 108 | AY.43 | 0.000478 |
N | 308 | A308S | Gcc | Tcc | 102 | 102 | AY.25 | 0.000614 |
N | 308 | A308S | Gcc | Tcc | 75 | 75 | B.1.617.2 | 0.000282 |
N | 308 | A308S | Gcc | Tcc | 63 | 63 | AY.3.1 | 0.005371 |
N | 308 | A308S | Gcc | Tcc | 56 | 56 | AY.9.2 | 0.002057 |
N | 308 | A308S | Gcc | Tcc | 48 | 48 | Q.2 | 0.029448 |
N | 308 | A308S | Gcc | Tcc | 47 | 47 | B.1.177 | 0.000619 |
N | 308 | A308S | Gcc | Tcc | 46 | 46 | AY.103 | 0.000286 |
N | 308 | A308S | Gcc | Tcc | 44 | 44 | B.1 | 0.000403 |
N | 308 | A308S | Gcc | Tcc | 39 | 39 | AY.75.1 | 0.007032 |
N | 308 | A308S | Gcc | Tcc | 38 | 38 | B.1.429 | 0.000894 |
N | 308 | A308S | Gcc | Tcc | 34 | 34 | AY.44 | 0.000207 |
N | 308 | A308S | Gcc | Tcc | 32 | 32 | P.2 | 0.005972 |
N | 308 | A308S | Gcc | Tcc | 31 | 31 | AY.98.1 | 0.001501 |
N | 308 | A308S | Gcc | Tcc | 30 | 30 | R.1 | 0.0027 |
N | 308 | A308S | Gcc | Tcc | 26 | 26 | B.1.1 | 0.000472 |
N | 308 | A308S | Gcc | Tcc | 25 | 25 | B.1.1.37 | 0.004822 |
N | 308 | A308S | Gcc | Tcc | 22 | 22 | AY.5 | 0.000454 |
N | 308 | A308S | Gcc | Tcc | 19 | 19 | B.1.258 | 0.001264 |
N | 308 | A308S | Gcc | Tcc | 18 | 18 | AY.117 | 0.001521 |
N | 308 | A308S | Gcc | Tcc | 16 | 16 | AY.102 | 0.000424 |
N | 308 | A308S | Gcc | Tcc | 15 | 15 | AY.20 | 0.000583 |
N | 308 | A308S | Gcc | Tcc | 14 | 14 | AY.120 | 0.000521 |
N | 308 | A308S | Gcc | Tcc | 14 | 14 | AY.23 | 0.000976 |
N | 308 | A308S | Gcc | Tcc | 14 | 14 | C.16 | 0.014846 |
N | 308 | A308S | Gcc | Tcc | 12 | 12 | AY.39 | 0.000297 |
N | 308 | A308S | Gcc | Tcc | 12 | 12 | B.1.380 | 0.07947 |
N | 308 | A308S | Gcc | Tcc | 11 | 11 | P.1 | 0.000173 |
N | 308 | A308S | Gcc | Tcc | 11 | 11 | Q.1 | 0.00139 |
N | 308 | A308S | Gcc | Tcc | 10 | 10 | AY.4.2 | 0.000217 |
N | 308 | A308S | Gcc | Tcc | 10 | 10 | AY.74 | 0.001156 |
N | 308 | A308S | Gcc | Tcc | 10 | 10 | B.1.221 | 0.00071 |
N | 308 | A308S | Gcc | Tcc | 9 | 9 | AY.116.1 | 0.002803 |
N | 308 | A308S | Gcc | Tcc | 9 | 9 | AY.75 | 0.000504 |
N | 308 | A308S | Gcc | Tcc | 9 | 9 | B.1.234 | 0.001187 |
N | 308 | A308S | Gcc | Tcc | 8 | 8 | B.1.596 | 0.000697 |
N | 308 | A308S | Gcc | Tcc | 8 | 8 | P.1.15 | 0.001859 |
N | 308 | A308S | Gcc | Tcc | 7 | 7 | AY.100 | 0.000322 |
N | 308 | A308S | Gcc | Tcc | 7 | 7 | AY.4.2.1 | 0.001043 |
N | 308 | A308S | Gcc | Tcc | 7 | 7 | AY.47 | 0.000218 |
N | 308 | A308S | Gcc | Tcc | 6 | 6 | AY.42 | 0.000241 |
N | 308 | A308S | Gcc | Tcc | 6 | 6 | AY.85 | 0.002563 |
N | 308 | A308S | Gcc | Tcc | 6 | 6 | B.1.609 | 0.002876 |
N | 308 | A308S | Gcc | Tcc | 6 | 6 | B.1.617.1 | 0.000774 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.23.1 | 0.002087 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.29 | 0.000079 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.29.1 | 0.001103 |
N | 308 | A308S | Gcc | Tcc | 4 | 5 | AY.3 | 0.00004 |
N | 308 | A308S | GCc | AGc | 1 | 5 | AY.3 | 0.00001 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.35 | 0.001165 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.36 | 0.000741 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.39.1 | 0.000198 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.68 | 0.001369 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | AY.99.2 | 0.000461 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | B.1.1.214 | 0.000277 |
N | 308 | A308S | Gcc | Tcc | 5 | 5 | B.1.427 | 0.000252 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | AY.26 | 0.000113 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | AY.45 | 0.000487 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | B.1.1.28 | 0.001245 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | B.1.1.398 | 0.012903 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | B.1.160 | 0.000125 |
N | 308 | A308S | Gcc | Tcc | 4 | 4 | P.1.17 | 0.000647 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | A.2.5 | 0.001497 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.1 | 0.001187 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.119 | 0.000106 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.12 | 0.000948 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.33 | 0.0002 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.58 | 0.002722 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | AY.7.1 | 0.000338 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.1.464 | 0.004418 |
N | 308 | A308S | GcC | TcT | 3 | 3 | B.1.1.519 | 0.000119 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.177.37 | 0.081081 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.177.81 | 0.000568 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.36 | 0.000438 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.525 | 0.000339 |
N | 308 | A308S | Gcc | Tcc | 3 | 3 | B.1.621 | 0.000266 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.106 | 0.00067 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.13 | 0.000322 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.16.1 | 0.00094 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.2 | 0.000712 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.34 | 0.000194 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.46 | 0.000208 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.46.6 | 0.000144 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.5.4 | 0.000553 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.61 | 0.00021 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.67 | 0.000929 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.9.1 | 0.000167 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | AY.98 | 0.000158 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.1.1 | 0.000653 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.146 | 0.008475 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.177.16 | 0.001329 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.177.60 | 0.000437 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.243 | 0.000139 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.36.17 | 0.000988 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.503 | 0.004975 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.526 | 0.000047 |
N | 308 | A308S | Gcc | Tcc | 2 | 2 | B.1.588 | 0.00182 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | A.23.1 | 0.000704 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.10 | 0.00053 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.101 | 0.00049 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.27 | 0.000065 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.32 | 0.000532 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.38 | 0.000499 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.46.2 | 0.000635 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.46.5 | 0.000198 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.49 | 0.003195 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.54 | 0.000095 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.56 | 0.001605 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.64 | 0.000595 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.65 | 0.000533 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.73 | 0.000665 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.8 | 0.000606 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.87 | 0.000833 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | AY.94 | 0.000443 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B | 0.000128 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.10 | 0.001115 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.138 | 0.006061 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.184 | 0.058824 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.194 | 0.00495 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.198 | 0.001468 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.222 | 0.000204 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.232 | 0.001815 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.269 | 0.001353 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.272 | 0.005208 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.277 | 0.000759 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.294 | 0.001266 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.317 | 0.000412 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.322 | 0.008772 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.373 | 0.02381 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.377 | 0.001381 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.39 | 0.00051 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.433 | 0.001425 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.1.89 | 0.006061 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.13 | 0.002375 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.177.15 | 0.000631 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.177.21 | 0.000076 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.177.4 | 0.000211 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.214 | 0.003663 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.241 | 0.000812 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.311 | 0.000275 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.314 | 0.007519 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.320 | 0.001245 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.351 | 0.00003 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.36.1 | 0.00114 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.398 | 0.002976 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.399 | 0.001934 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.400 | 0.000429 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.404 | 0.001302 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.456 | 0.003268 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.527 | 0.003704 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.1.575 | 0.000303 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.4 | 0.002208 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | B.40 | 0.000364 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | C.35 | 0.000774 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | C.37 | 0.000116 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | C.37.1 | 0.002618 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | D.2 | 0.000075 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | K.3 | 0.006173 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | L.3 | 0.003546 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | P.1.14 | 0.000048 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | P.1.7 | 0.000319 |
N | 308 | A308S | Gcc | Tcc | 1 | 1 | P.1.8 | 0.004785 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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