CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 252 | A252S | nonsyn | Gct | Tct | 3379 | 3379 | 1 | 29027-29029 |
Details of the mutation A252S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 252 | A252S | Gct | Tct | 3379 | 3379 | All | 0.000646 |
N | 252 | A252S | Gct | Tct | 478 | 478 | AY.4 | 0.000744 |
N | 252 | A252S | Gct | Tct | 414 | 414 | B.1.1.7 | 0.000371 |
N | 252 | A252S | Gct | Tct | 404 | 404 | AY.39 | 0.009983 |
N | 252 | A252S | Gct | Tct | 315 | 315 | B.1.1.298 | 0.271552 |
N | 252 | A252S | Gct | Tct | 288 | 288 | B.1.177.19 | 0.412017 |
N | 252 | A252S | Gct | Tct | 128 | 128 | B.1.351 | 0.003805 |
N | 252 | A252S | Gct | Tct | 104 | 104 | B.1.617.2 | 0.000392 |
N | 252 | A252S | Gct | Tct | 81 | 81 | AY.43 | 0.000359 |
N | 252 | A252S | Gct | Tct | 80 | 80 | B.1.243 | 0.005567 |
N | 252 | A252S | Gct | Tct | 72 | 72 | AY.103 | 0.000447 |
N | 252 | A252S | Gct | Tct | 66 | 66 | B.1 | 0.000605 |
N | 252 | A252S | Gct | Tct | 60 | 60 | B.1.177.79 | 0.140515 |
N | 252 | A252S | Gct | Tct | 54 | 54 | B.1.160 | 0.001684 |
N | 252 | A252S | Gct | Tct | 53 | 53 | AY.44 | 0.000323 |
N | 252 | A252S | Gct | Tct | 45 | 45 | AY.9.2.1 | 0.088933 |
N | 252 | A252S | Gct | Tct | 41 | 41 | AY.3 | 0.000408 |
N | 252 | A252S | Gct | Tct | 36 | 36 | AY.80 | 0.040632 |
N | 252 | A252S | Gct | Tct | 30 | 30 | AY.25 | 0.00018 |
N | 252 | A252S | Gct | Tct | 29 | 29 | B.1.1 | 0.000526 |
N | 252 | A252S | Gct | Tct | 27 | 27 | B.1.2 | 0.000238 |
N | 252 | A252S | Gct | Tct | 27 | 27 | P.1 | 0.000425 |
N | 252 | A252S | Gct | Tct | 26 | 26 | B.1.177 | 0.000342 |
N | 252 | A252S | Gct | Tct | 20 | 20 | B.1.1.207 | 0.023641 |
N | 252 | A252S | Gct | Tct | 20 | 20 | B.1.1.70 | 0.006821 |
N | 252 | A252S | Gct | Tct | 15 | 15 | B.1.1.369 | 0.006693 |
N | 252 | A252S | Gct | Tct | 15 | 15 | B.1.177.29 | 1 |
N | 252 | A252S | Gct | Tct | 14 | 14 | B.1.1.519 | 0.000556 |
N | 252 | A252S | Gct | Tct | 13 | 13 | B.1.120 | 0.1 |
N | 252 | A252S | Gct | Tct | 13 | 13 | B.1.429 | 0.000306 |
N | 252 | A252S | Gct | Tct | 12 | 12 | B.1.526 | 0.000282 |
N | 252 | A252S | Gct | Tct | 11 | 11 | AY.120 | 0.000409 |
N | 252 | A252S | Gct | Tct | 10 | 10 | AY.20 | 0.000389 |
N | 252 | A252S | Gct | Tct | 9 | 9 | AY.102 | 0.000239 |
N | 252 | A252S | Gct | Tct | 9 | 9 | AY.64 | 0.005357 |
N | 252 | A252S | Gct | Tct | 8 | 8 | AY.98 | 0.000632 |
N | 252 | A252S | Gct | Tct | 8 | 8 | B.1.1.153 | 0.008762 |
N | 252 | A252S | Gct | Tct | 8 | 8 | B.1.596 | 0.000697 |
N | 252 | A252S | Gct | Tct | 7 | 7 | AY.45 | 0.000852 |
N | 252 | A252S | Gct | Tct | 7 | 7 | AY.9.2 | 0.000257 |
N | 252 | A252S | Gct | Tct | 7 | 7 | AY.98.1 | 0.000339 |
N | 252 | A252S | Gct | Tct | 7 | 7 | B.1.575 | 0.002124 |
N | 252 | A252S | Gct | Tct | 7 | 7 | P.1.7 | 0.002235 |
N | 252 | A252S | Gct | Tct | 6 | 6 | AY.117 | 0.000507 |
N | 252 | A252S | Gct | Tct | 6 | 6 | AY.33 | 0.000401 |
N | 252 | A252S | Gct | Tct | 6 | 6 | AY.46.5 | 0.00119 |
N | 252 | A252S | Gct | Tct | 6 | 6 | AY.99 | 0.006296 |
N | 252 | A252S | Gct | Tct | 6 | 6 | B.1.1.318 | 0.001811 |
N | 252 | A252S | Gct | Tct | 6 | 6 | D.2 | 0.00045 |
N | 252 | A252S | Gct | Tct | 6 | 6 | Q.4 | 0.002729 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.100 | 0.00023 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.23 | 0.000349 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.26 | 0.000142 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.29 | 0.000079 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.39.1 | 0.000198 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.41 | 0.00147 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.5 | 0.000103 |
N | 252 | A252S | Gct | Tct | 5 | 5 | AY.61 | 0.000524 |
N | 252 | A252S | Gct | Tct | 5 | 5 | B.1.1.311 | 0.001791 |
N | 252 | A252S | Gct | Tct | 5 | 5 | B.1.221 | 0.000355 |
N | 252 | A252S | Gct | Tct | 5 | 5 | B.1.351.3 | 0.004382 |
N | 252 | A252S | Gct | Tct | 5 | 5 | B.1.36 | 0.00073 |
N | 252 | A252S | Gct | Tct | 5 | 5 | B.1.619.1 | 0.003207 |
N | 252 | A252S | Gct | Tct | 4 | 4 | AY.119 | 0.000141 |
N | 252 | A252S | Gct | Tct | 4 | 4 | AY.75.1 | 0.000721 |
N | 252 | A252S | Gct | Tct | 4 | 4 | AY.9 | 0.00027 |
N | 252 | A252S | Gct | Tct | 4 | 4 | B.1.177.21 | 0.000306 |
N | 252 | A252S | Gct | Tct | 4 | 4 | B.1.258 | 0.000266 |
N | 252 | A252S | Gct | Tct | 3 | 3 | AY.16.1 | 0.00141 |
N | 252 | A252S | Gct | Tct | 3 | 3 | AY.46 | 0.000312 |
N | 252 | A252S | Gct | Tct | 3 | 3 | AY.47 | 0.000093 |
N | 252 | A252S | Gct | Tct | 3 | 3 | AY.7.1 | 0.000338 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B | 0.000383 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.1.1.222 | 0.000612 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.1.1.306 | 0.001315 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.1.369 | 0.000856 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.1.525 | 0.000339 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.1.617.1 | 0.000387 |
N | 252 | A252S | Gct | Tct | 3 | 3 | B.4 | 0.006623 |
N | 252 | A252S | Gct | Tct | 3 | 3 | P.1.14 | 0.000143 |
N | 252 | A252S | Gct | Tct | 3 | 3 | P.1.4 | 0.00293 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.116 | 0.000574 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.121 | 0.000271 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.14 | 0.000176 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.30 | 0.000791 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.36 | 0.000296 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.4.2 | 0.000043 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.4.5 | 0.000215 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.5.3 | 0.000675 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.53 | 0.000575 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.77 | 0.002255 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.9.1 | 0.000167 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.94 | 0.000885 |
N | 252 | A252S | Gct | Tct | 2 | 2 | AY.95 | 0.001522 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.1.164 | 0.010309 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.1.214 | 0.000111 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.1.25 | 0.001137 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.1.33 | 0.000842 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.1.434 | 0.000697 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.177.32 | 0.002699 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.177.73 | 0.001133 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.301 | 0.011834 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.396 | 0.001411 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.427 | 0.000101 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.539 | 0.035088 |
N | 252 | A252S | Gct | Tct | 2 | 2 | B.1.621 | 0.000177 |
N | 252 | A252S | Gct | Tct | 2 | 2 | P.2 | 0.000373 |
N | 252 | A252S | Gct | Tct | 2 | 2 | R.1 | 0.00018 |
N | 252 | A252S | Gct | Tct | 1 | 1 | A | 0.000387 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.101 | 0.00049 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.106 | 0.000335 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.109 | 0.00074 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.110 | 0.000113 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.111 | 0.000183 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.113 | 0.000142 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.118 | 0.000063 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.12 | 0.000316 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.16 | 0.00038 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.22 | 0.002092 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.23.1 | 0.000417 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.24 | 0.000431 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.3.1 | 0.000085 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.34 | 0.000097 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.4.4 | 0.000409 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.42 | 0.00004 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.46.3 | 0.000934 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.46.4 | 0.000165 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.54 | 0.000095 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.55 | 0.000917 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.6 | 0.000041 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.65 | 0.000533 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.67 | 0.000464 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.7 | 0.000196 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.70 | 0.000209 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.74 | 0.000116 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.85 | 0.000427 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.87 | 0.000833 |
N | 252 | A252S | Gct | Tct | 1 | 1 | AY.99.2 | 0.000092 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.10 | 0.001115 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.28 | 0.000311 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.296 | 0.018182 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.397 | 0.002252 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.409 | 0.002833 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.507 | 0.008696 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.58 | 0.005376 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.1.83 | 0.00271 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.110.3 | 0.000718 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.13 | 0.002375 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.139 | 0.000733 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.160.26 | 0.002421 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.177.55 | 0.002331 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.177.57 | 0.000281 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.177.75 | 0.001041 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.236 | 0.002053 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.237 | 0.004975 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.240 | 0.000216 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.258.11 | 0.000396 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.265 | 0.001271 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.281 | 0.021739 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.311 | 0.000275 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.351.2 | 0.000303 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.36.35 | 0.002604 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.36.7 | 0.004 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.367 | 0.000792 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.409 | 0.000781 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.459 | 0.004082 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.473 | 0.019231 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.517 | 0.000427 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.523 | 0.002451 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.524 | 0.001406 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.540 | 0.009709 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.560 | 0.00463 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.561 | 0.000397 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.570 | 0.002941 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.610 | 0.003546 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.620 | 0.000946 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.621.1 | 0.000506 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.623 | 0.000536 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.1.627 | 0.00202 |
N | 252 | A252S | Gct | Tct | 1 | 1 | B.40 | 0.000364 |
N | 252 | A252S | Gct | Tct | 1 | 1 | C.1 | 0.002392 |
N | 252 | A252S | Gct | Tct | 1 | 1 | C.26 | 0.007353 |
N | 252 | A252S | Gct | Tct | 1 | 1 | C.37 | 0.000116 |
N | 252 | A252S | Gct | Tct | 1 | 1 | P.1.10 | 0.000269 |
N | 252 | A252S | Gct | Tct | 1 | 1 | P.1.13 | 0.000898 |
N | 252 | A252S | Gct | Tct | 1 | 1 | P.1.17 | 0.000162 |
N | 252 | A252S | Gct | Tct | 1 | 1 | P.1.17.1 | 0.000875 |
N | 252 | A252S | Gct | Tct | 1 | 1 | Q.8 | 0.000165 |
N | 252 | A252S | Gct | Tct | 1 | 1 | U.1 | 0.012821 |
![]() |
![]() |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
|