CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : Mut = A182D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	182	A182D		nonsyn	gCc	gAc	97	97	1	28817-28819

Details of the mutation A182D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	182	A182D	gCc	gAc	97	97	All	0.000019
N	182	A182D	gCc	gAc	46	46	P.2	0.008585
N	182	A182D	gCc	gAc	20	20	B.1.1.7	0.000018
N	182	A182D	gCc	gAc	6	6	AY.4	0.000009
N	182	A182D	gCc	gAc	4	4	AY.103	0.000025
N	182	A182D	gCc	gAc	3	3	B.1	0.000027
N	182	A182D	gCc	gAc	2	2	B.1.2	0.000018
N	182	A182D	gCc	gAc	2	2	B.1.617.2	0.000008
N	182	A182D	gCc	gAc	1	1		0.055556
N	182	A182D	gCc	gAc	1	1	AY.116	0.000287
N	182	A182D	gCc	gAc	1	1	AY.118	0.000063
N	182	A182D	gCc	gAc	1	1	AY.20	0.000039
N	182	A182D	gCc	gAc	1	1	AY.3	0.00001
N	182	A182D	gCc	gAc	1	1	AY.42	0.00004
N	182	A182D	gCc	gAc	1	1	AY.43	0.000004
N	182	A182D	gCc	gAc	1	1	AY.44	0.000006
N	182	A182D	gCc	gAc	1	1	B.1.1.28	0.000311
N	182	A182D	gCc	gAc	1	1	B.1.221	0.000071
N	182	A182D	gCc	gAc	1	1	B.1.375	0.00082
N	182	A182D	gCc	gAc	1	1	B.1.561	0.000397
N	182	A182D	gCc	gAc	1	1	P.1	0.000016
N	182	A182D	gCc	gAc	1	1	Q.3	0.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.