CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 173 | A173A | syn | gcA | gcT | 3810 | 3343 | 0.877428 | 28790-28792 | |
N | 173 | A173A | syn | gcA | gcG | 3810 | 427 | 0.112073 | 28790-28792 | |
N | 173 | A173A | syn | gcA | gcC | 3810 | 40 | 0.0104987 | 28790-28792 |
Details of the mutation A173A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 173 | A173A | gcA | gcT | 3343 | 3810 | All | 0.000639 |
N | 173 | A173A | gcA | gcG | 427 | 3810 | All | 0.000082 |
N | 173 | A173A | gcA | gcC | 40 | 3810 | All | 0.000008 |
N | 173 | A173A | gcA | gcT | 934 | 936 | B.1.429 | 0.021976 |
N | 173 | A173A | gcA | gcG | 2 | 936 | B.1.429 | 0.000047 |
N | 173 | A173A | gcA | gcT | 354 | 451 | B.1.1.7 | 0.000317 |
N | 173 | A173A | gcA | gcG | 97 | 451 | B.1.1.7 | 0.000087 |
N | 173 | A173A | gcA | gcT | 313 | 317 | AY.103 | 0.001943 |
N | 173 | A173A | gcA | gcG | 4 | 317 | AY.103 | 0.000025 |
N | 173 | A173A | gcA | gcT | 171 | 250 | AY.4 | 0.000266 |
N | 173 | A173A | gcA | gcG | 50 | 250 | AY.4 | 0.000078 |
N | 173 | A173A | gcA | gcC | 29 | 250 | AY.4 | 0.000045 |
N | 173 | A173A | gcA | gcT | 167 | 168 | B.1 | 0.00153 |
N | 173 | A173A | gcA | gcG | 1 | 168 | B.1 | 0.000009 |
N | 173 | A173A | gcA | gcT | 149 | 156 | B.1.2 | 0.001312 |
N | 173 | A173A | gcA | gcG | 7 | 156 | B.1.2 | 0.000062 |
N | 173 | A173A | gcA | gcT | 147 | 149 | P.1 | 0.002316 |
N | 173 | A173A | gcA | gcG | 2 | 149 | P.1 | 0.000032 |
N | 173 | A173A | gcA | gcT | 137 | 137 | B.1.9.4 | 0.840491 |
N | 173 | A173A | gcA | gcT | 87 | 104 | B.1.617.2 | 0.000328 |
N | 173 | A173A | gcA | gcG | 17 | 104 | B.1.617.2 | 0.000064 |
N | 173 | A173A | gcA | gcT | 76 | 82 | B.1.177 | 0.001001 |
N | 173 | A173A | gcA | gcG | 6 | 82 | B.1.177 | 0.000079 |
N | 173 | A173A | gcA | gcT | 65 | 67 | AY.39 | 0.001606 |
N | 173 | A173A | gcA | gcG | 2 | 67 | AY.39 | 0.000049 |
N | 173 | A173A | gcA | gcG | 51 | 62 | AY.119 | 0.001801 |
N | 173 | A173A | gcA | gcT | 11 | 62 | AY.119 | 0.000388 |
N | 173 | A173A | gcA | gcT | 53 | 60 | B.1.1 | 0.000961 |
N | 173 | A173A | gcA | gcG | 7 | 60 | B.1.1 | 0.000127 |
N | 173 | A173A | gcA | gcT | 40 | 50 | AY.44 | 0.000243 |
N | 173 | A173A | gcA | gcG | 10 | 50 | AY.44 | 0.000061 |
N | 173 | A173A | gcA | gcT | 48 | 48 | AY.3 | 0.000477 |
N | 173 | A173A | gcA | gcT | 37 | 41 | AY.43 | 0.000164 |
N | 173 | A173A | gcA | gcG | 4 | 41 | AY.43 | 0.000018 |
N | 173 | A173A | gcA | gcG | 40 | 40 | B.1.177.32 | 0.053981 |
N | 173 | A173A | gcA | gcT | 30 | 30 | AY.47 | 0.000933 |
N | 173 | A173A | gcA | gcT | 26 | 26 | B.1.1.328 | 0.440678 |
N | 173 | A173A | gcA | gcG | 22 | 23 | B.1.258 | 0.001464 |
N | 173 | A173A | gcA | gcT | 1 | 23 | B.1.258 | 0.000067 |
N | 173 | A173A | gcA | gcT | 23 | 23 | B.1.258.17 | 0.002391 |
N | 173 | A173A | gcA | gcT | 23 | 23 | B.1.427 | 0.001161 |
N | 173 | A173A | gcA | gcT | 22 | 22 | AY.100 | 0.001012 |
N | 173 | A173A | gcA | gcT | 22 | 22 | B.1.1.317 | 0.009057 |
N | 173 | A173A | gcA | gcT | 20 | 20 | AY.9.2 | 0.000735 |
N | 173 | A173A | gcA | gcT | 14 | 16 | AY.102 | 0.000371 |
N | 173 | A173A | gcA | gcG | 2 | 16 | AY.102 | 0.000053 |
N | 173 | A173A | gcA | gcG | 16 | 16 | B.1.554 | 0.070485 |
N | 173 | A173A | gcA | gcG | 9 | 15 | B | 0.00115 |
N | 173 | A173A | gcA | gcT | 6 | 15 | B | 0.000767 |
N | 173 | A173A | gcA | gcG | 9 | 14 | B.1.637 | 0.000658 |
N | 173 | A173A | gcA | gcT | 5 | 14 | B.1.637 | 0.000365 |
N | 173 | A173A | gcA | gcT | 13 | 13 | AY.110 | 0.001465 |
N | 173 | A173A | gcA | gcT | 9 | 13 | AY.25 | 0.000054 |
N | 173 | A173A | gcA | gcG | 4 | 13 | AY.25 | 0.000024 |
N | 173 | A173A | gcA | gcT | 13 | 13 | AY.98.1 | 0.00063 |
N | 173 | A173A | gcA | gcT | 12 | 12 | AY.23 | 0.000837 |
N | 173 | A173A | gcA | gcT | 12 | 12 | AY.5 | 0.000248 |
N | 173 | A173A | gcA | gcG | 8 | 12 | B.1.596 | 0.000697 |
N | 173 | A173A | gcA | gcT | 4 | 12 | B.1.596 | 0.000349 |
N | 173 | A173A | gcA | gcT | 11 | 11 | P.1.12 | 0.005324 |
N | 173 | A173A | gcA | gcT | 10 | 10 | AY.30 | 0.003957 |
N | 173 | A173A | gcA | gcT | 7 | 10 | B.1.351 | 0.000208 |
N | 173 | A173A | gcA | gcG | 2 | 10 | B.1.351 | 0.000059 |
N | 173 | A173A | gcA | gcC | 1 | 10 | B.1.351 | 0.00003 |
N | 173 | A173A | gcA | gcG | 9 | 10 | B.1.617.1 | 0.001161 |
N | 173 | A173A | gcA | gcT | 1 | 10 | B.1.617.1 | 0.000129 |
N | 173 | A173A | gcA | gcT | 9 | 9 | B.1.525 | 0.001018 |
N | 173 | A173A | gcA | gcT | 8 | 8 | B.1.1.318 | 0.002414 |
N | 173 | A173A | gcA | gcT | 8 | 8 | B.1.621 | 0.000708 |
N | 173 | A173A | gcA | gcT | 5 | 8 | D.2 | 0.000375 |
N | 173 | A173A | gcA | gcG | 3 | 8 | D.2 | 0.000225 |
N | 173 | A173A | gcA | gcT | 7 | 7 | AY.20 | 0.000272 |
N | 173 | A173A | gcA | gcT | 5 | 7 | AY.29 | 0.000079 |
N | 173 | A173A | gcA | gcG | 2 | 7 | AY.29 | 0.000032 |
N | 173 | A173A | gcA | gcT | 7 | 7 | AY.39.1 | 0.000277 |
N | 173 | A173A | gcA | gcT | 7 | 7 | AY.42 | 0.000282 |
N | 173 | A173A | gcA | gcT | 7 | 7 | B.1.111 | 0.008226 |
N | 173 | A173A | gcA | gcT | 6 | 6 | AY.4.2 | 0.00013 |
N | 173 | A173A | gcA | gcT | 6 | 6 | AY.69 | 0.00112 |
N | 173 | A173A | gcA | gcG | 4 | 6 | AY.9 | 0.00027 |
N | 173 | A173A | gcA | gcT | 2 | 6 | AY.9 | 0.000135 |
N | 173 | A173A | gcA | gcG | 4 | 6 | B.1.177.73 | 0.002265 |
N | 173 | A173A | gcA | gcT | 2 | 6 | B.1.177.73 | 0.001133 |
N | 173 | A173A | gcA | gcT | 6 | 6 | P.1.14 | 0.000287 |
N | 173 | A173A | gcA | gcT | 6 | 6 | P.1.15 | 0.001394 |
N | 173 | A173A | gcA | gcC | 5 | 5 | AY.94 | 0.002213 |
N | 173 | A173A | gcA | gcT | 5 | 5 | B.1.1.335 | 0.064935 |
N | 173 | A173A | gcA | gcT | 3 | 5 | B.1.36 | 0.000438 |
N | 173 | A173A | gcA | gcG | 2 | 5 | B.1.36 | 0.000292 |
N | 173 | A173A | gcA | gcT | 5 | 5 | B.1.36.27 | 0.003817 |
N | 173 | A173A | gcA | gcT | 4 | 5 | B.1.526 | 0.000094 |
N | 173 | A173A | gcA | gcG | 1 | 5 | B.1.526 | 0.000024 |
N | 173 | A173A | gcA | gcT | 5 | 5 | B.1.9 | 0.030864 |
N | 173 | A173A | gcA | gcT | 4 | 4 | AY.118 | 0.000251 |
N | 173 | A173A | gcA | gcT | 3 | 4 | AY.33 | 0.0002 |
N | 173 | A173A | gcA | gcG | 1 | 4 | AY.33 | 0.000067 |
N | 173 | A173A | gcA | gcT | 3 | 4 | AY.49 | 0.009585 |
N | 173 | A173A | gcA | gcG | 1 | 4 | AY.49 | 0.003195 |
N | 173 | A173A | gcA | gcT | 4 | 4 | AY.70 | 0.000834 |
N | 173 | A173A | gcA | gcT | 4 | 4 | B.1.369 | 0.001141 |
N | 173 | A173A | gcA | gcT | 4 | 4 | B.1.425 | 0.011976 |
N | 173 | A173A | gcA | gcT | 4 | 4 | B.1.9.5 | 0.022727 |
N | 173 | A173A | gcA | gcT | 3 | 3 | AY.113 | 0.000427 |
N | 173 | A173A | gcA | gcT | 3 | 3 | AY.7.1 | 0.000338 |
N | 173 | A173A | gcA | gcT | 3 | 3 | AY.75 | 0.000168 |
N | 173 | A173A | gcA | gcT | 3 | 3 | AY.99.2 | 0.000276 |
N | 173 | A173A | gcA | gcT | 3 | 3 | B.1.1.1 | 0.00098 |
N | 173 | A173A | gcA | gcT | 3 | 3 | B.1.1.101 | 0.03 |
N | 173 | A173A | gcA | gcT | 3 | 3 | B.1.1.50 | 0.002037 |
N | 173 | A173A | gcA | gcT | 3 | 3 | B.1.160 | 0.000094 |
N | 173 | A173A | gcA | gcG | 3 | 3 | B.1.177.58 | 0.003995 |
N | 173 | A173A | gcA | gcT | 3 | 3 | B.1.426 | 0.003027 |
N | 173 | A173A | gcA | gcT | 2 | 2 | A | 0.000774 |
N | 173 | A173A | gcA | gcT | 2 | 2 | AY.121 | 0.000271 |
N | 173 | A173A | gcA | gcT | 2 | 2 | AY.2 | 0.000712 |
N | 173 | A173A | gcA | gcG | 1 | 2 | AY.4.2.1 | 0.000149 |
N | 173 | A173A | gcA | gcC | 1 | 2 | AY.4.2.1 | 0.000149 |
N | 173 | A173A | gcA | gcT | 2 | 2 | AY.6 | 0.000082 |
N | 173 | A173A | gcA | gcT | 2 | 2 | AY.61 | 0.00021 |
N | 173 | A173A | gcA | gcT | 1 | 2 | AY.9.1 | 0.000084 |
N | 173 | A173A | gcA | gcG | 1 | 2 | AY.9.1 | 0.000084 |
N | 173 | A173A | gcA | gcG | 1 | 2 | AY.92 | 0.000287 |
N | 173 | A173A | gcA | gcT | 1 | 2 | AY.92 | 0.000287 |
N | 173 | A173A | gcA | gcG | 2 | 2 | B.1.1.141 | 0.004024 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.1.373 | 0.047619 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.1.519 | 0.000079 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.146 | 0.008475 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.177.15 | 0.001262 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.177.4 | 0.000422 |
N | 173 | A173A | gcA | gcG | 1 | 2 | B.1.177.60 | 0.000218 |
N | 173 | A173A | gcA | gcT | 1 | 2 | B.1.177.60 | 0.000218 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.177.75 | 0.002081 |
N | 173 | A173A | gcA | gcG | 1 | 2 | B.1.221 | 0.000071 |
N | 173 | A173A | gcA | gcT | 1 | 2 | B.1.221 | 0.000071 |
N | 173 | A173A | gcA | gcG | 1 | 2 | B.1.234 | 0.000132 |
N | 173 | A173A | gcA | gcT | 1 | 2 | B.1.234 | 0.000132 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.324 | 0.00321 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.36.26 | 0.005714 |
N | 173 | A173A | gcA | gcT | 2 | 2 | B.1.389 | 0.002004 |
N | 173 | A173A | gcA | gcG | 2 | 2 | B.1.466.2 | 0.000782 |
N | 173 | A173A | gcA | gcC | 2 | 2 | B.1.497 | 0.00063 |
N | 173 | A173A | gcA | gcT | 1 | 2 | B.1.595 | 0.000261 |
N | 173 | A173A | gcA | gcG | 1 | 2 | B.1.595 | 0.000261 |
N | 173 | A173A | gcA | gcT | 2 | 2 | C.36 | 0.001821 |
N | 173 | A173A | gcA | gcT | 2 | 2 | P.1.17 | 0.000324 |
N | 173 | A173A | gcA | gcT | 2 | 2 | P.2 | 0.000373 |
N | 173 | A173A | gcA | gcT | 2 | 2 | Q.8 | 0.00033 |
N | 173 | A173A | gcA | gcT | 1 | 1 | A.2.4 | 0.003367 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AE.8 | 0.000489 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AP.1 | 0.001502 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AU.3 | 0.00211 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.108 | 0.001103 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.114 | 0.000231 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.116 | 0.000287 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.116.1 | 0.000311 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.117 | 0.000085 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.120 | 0.000037 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.16 | 0.00038 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.16.1 | 0.00047 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.3.1 | 0.000085 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.34 | 0.000097 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.34.1 | 0.00051 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.37 | 0.000316 |
N | 173 | A173A | gcA | gcG | 1 | 1 | AY.38 | 0.000499 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.4.5 | 0.000107 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.45 | 0.000122 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.46.2 | 0.000635 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.46.6 | 0.000072 |
N | 173 | A173A | gcA | gcG | 1 | 1 | AY.5.2 | 0.002463 |
N | 173 | A173A | gcA | gcG | 1 | 1 | AY.55 | 0.000917 |
N | 173 | A173A | gcA | gcG | 1 | 1 | AY.74 | 0.000116 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.75.1 | 0.00018 |
N | 173 | A173A | gcA | gcG | 1 | 1 | AY.79 | 0.001211 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.84 | 0.000437 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.87 | 0.000833 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.93 | 0.000273 |
N | 173 | A173A | gcA | gcT | 1 | 1 | AY.98 | 0.000079 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.135 | 0.004695 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.176 | 0.000439 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.192 | 0.002309 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.214 | 0.000055 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.216 | 0.00089 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.262 | 0.015152 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.277 | 0.000759 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.28 | 0.000311 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.363 | 0.005988 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.389 | 0.006061 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.1.409 | 0.002833 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.422 | 0.045455 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.1.448 | 0.002033 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.1.63 | 0.000386 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.177.12 | 0.000152 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.177.16 | 0.000664 |
N | 173 | A173A | gcA | gcC | 1 | 1 | B.1.177.56 | 0.000668 |
N | 173 | A173A | gcA | gcC | 1 | 1 | B.1.177.63 | 0.002703 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.177.65 | 0.000665 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.177.86 | 0.000183 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.189 | 0.004292 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.192 | 0.009259 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.22 | 0.001318 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.221.1 | 0.002907 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.221.4 | 0.004167 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.233 | 0.014085 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.240 | 0.000216 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.243 | 0.00007 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.311 | 0.000275 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.36.17 | 0.000494 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.367 | 0.000792 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.400 | 0.000429 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.409 | 0.000781 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.432 | 0.011236 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.456 | 0.003268 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.501 | 0.007353 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.533 | 0.009615 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.560 | 0.00463 |
N | 173 | A173A | gcA | gcT | 1 | 1 | B.1.564 | 0.000426 |
N | 173 | A173A | gcA | gcG | 1 | 1 | B.1.628 | 0.000352 |
N | 173 | A173A | gcA | gcT | 1 | 1 | C.1 | 0.002392 |
N | 173 | A173A | gcA | gcT | 1 | 1 | C.14 | 0.004329 |
N | 173 | A173A | gcA | gcT | 1 | 1 | C.23 | 0.005814 |
N | 173 | A173A | gcA | gcG | 1 | 1 | C.26 | 0.007353 |
N | 173 | A173A | gcA | gcT | 1 | 1 | C.37 | 0.000116 |
N | 173 | A173A | gcA | gcT | 1 | 1 | C.38 | 0.008065 |
N | 173 | A173A | gcA | gcG | 1 | 1 | P.1.16 | 0.000374 |
N | 173 | A173A | gcA | gcT | 1 | 1 | P.1.7 | 0.000319 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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