CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 81 | D81D | syn | gaT | gaC | 1170 | 1170 | 1 | 28514-28516 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 81 | D81D | gaT | gaC | 1170 | 1170 | All | 0.000224 |
N | 81 | D81D | gaT | gaC | 229 | 229 | C.1.2 | 0.974468 |
N | 81 | D81D | gaT | gaC | 119 | 119 | B.1.177.73 | 0.067384 |
N | 81 | D81D | gaT | gaC | 103 | 103 | B.1.1.7 | 0.000092 |
N | 81 | D81D | gaT | gaC | 57 | 57 | B.1.1.50 | 0.038697 |
N | 81 | D81D | gaT | gaC | 50 | 50 | AY.4 | 0.000078 |
N | 81 | D81D | gaT | gaC | 45 | 45 | B.1.177 | 0.000593 |
N | 81 | D81D | gaT | gaC | 37 | 37 | B.1.617.2 | 0.000139 |
N | 81 | D81D | gaT | gaC | 34 | 34 | C.36.3.1 | 0.092391 |
N | 81 | D81D | gaT | gaC | 33 | 33 | AY.43 | 0.000146 |
N | 81 | D81D | gaT | gaC | 31 | 31 | AY.25 | 0.000186 |
N | 81 | D81D | gaT | gaC | 30 | 30 | B.1.177.21 | 0.002294 |
N | 81 | D81D | gaT | gaC | 28 | 28 | B.1.2 | 0.000247 |
N | 81 | D81D | gaT | gaC | 27 | 27 | AY.103 | 0.000168 |
N | 81 | D81D | gaT | gaC | 26 | 26 | B.1.1.328 | 0.440678 |
N | 81 | D81D | gaT | gaC | 24 | 24 | B.1.1 | 0.000435 |
N | 81 | D81D | gaT | gaC | 24 | 24 | B.1.214.2 | 0.014388 |
N | 81 | D81D | gaT | gaC | 18 | 18 | B.1.232 | 0.009672 |
N | 81 | D81D | gaT | gaC | 13 | 13 | AY.100 | 0.000598 |
N | 81 | D81D | gaT | gaC | 13 | 13 | AY.5 | 0.000268 |
N | 81 | D81D | gaT | gaC | 13 | 13 | AY.51 | 0.011818 |
N | 81 | D81D | gaT | gaC | 12 | 12 | AY.4.2 | 0.00026 |
N | 81 | D81D | gaT | gaC | 11 | 11 | B.1 | 0.000101 |
N | 81 | D81D | gaT | gaC | 9 | 9 | B.1.526 | 0.000212 |
N | 81 | D81D | gaT | gaC | 8 | 8 | AY.9 | 0.000541 |
N | 81 | D81D | gaT | gaC | 8 | 8 | AY.9.2 | 0.000294 |
N | 81 | D81D | gaT | gaC | 8 | 8 | B.1.1.39 | 0.004077 |
N | 81 | D81D | gaT | gaC | 8 | 8 | P.1 | 0.000126 |
N | 81 | D81D | gaT | gaC | 7 | 7 | AY.44 | 0.000043 |
N | 81 | D81D | gaT | gaC | 6 | 6 | AY.29 | 0.000095 |
N | 81 | D81D | gaT | gaC | 5 | 5 | AY.3 | 0.00005 |
N | 81 | D81D | gaT | gaC | 5 | 5 | AY.46 | 0.00052 |
N | 81 | D81D | gaT | gaC | 4 | 4 | AY.57 | 0.002625 |
N | 81 | D81D | gaT | gaC | 4 | 4 | B.1.1.348 | 0.003185 |
N | 81 | D81D | gaT | gaC | 4 | 4 | B.1.1.519 | 0.000159 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.102 | 0.00008 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.119 | 0.000106 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.120 | 0.000112 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.20 | 0.000117 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.26 | 0.000085 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.69 | 0.00056 |
N | 81 | D81D | gaT | gaC | 3 | 3 | AY.98.1 | 0.000145 |
N | 81 | D81D | gaT | gaC | 3 | 3 | B.1.1.354 | 0.013158 |
N | 81 | D81D | gaT | gaC | 3 | 3 | B.1.357 | 0.028571 |
N | 81 | D81D | gaT | gaC | 3 | 3 | C.35 | 0.002322 |
N | 81 | D81D | gaT | gaC | 3 | 3 | P.2 | 0.00056 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.12 | 0.000632 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.23 | 0.000139 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.34 | 0.000194 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.39 | 0.000049 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.56 | 0.00321 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.61 | 0.00021 |
N | 81 | D81D | gaT | gaC | 2 | 2 | AY.81 | 0.003984 |
N | 81 | D81D | gaT | gaC | 2 | 2 | B.1.1.134 | 0.022727 |
N | 81 | D81D | gaT | gaC | 2 | 2 | B.1.160 | 0.000062 |
N | 81 | D81D | gaT | gaC | 2 | 2 | B.1.36 | 0.000292 |
N | 81 | D81D | gaT | gaC | 2 | 2 | B.1.36.27 | 0.001527 |
N | 81 | D81D | gaT | gaC | 2 | 2 | C.1 | 0.004785 |
N | 81 | D81D | gaT | gaC | 2 | 2 | C.37 | 0.000232 |
N | 81 | D81D | gaT | gaC | 1 | 1 | A | 0.000387 |
N | 81 | D81D | gaT | gaC | 1 | 1 | A.1 | 0.000282 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.108 | 0.001103 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.117 | 0.000085 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.13 | 0.000161 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.16 | 0.00038 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.30 | 0.000396 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.33 | 0.000067 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.39.1 | 0.00004 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.4.3 | 0.000842 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.42 | 0.00004 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.45 | 0.000122 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.47 | 0.000031 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.5.3 | 0.000337 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.54 | 0.000095 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.6 | 0.000041 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.67 | 0.000464 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.72 | 0.001361 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.75.1 | 0.00018 |
N | 81 | D81D | gaT | gaC | 1 | 1 | AY.92 | 0.000287 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.1 | 0.000327 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.277 | 0.000759 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.28 | 0.000311 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.294 | 0.001266 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.312 | 0.001912 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.317 | 0.000412 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.326 | 0.001761 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.389 | 0.006061 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.402 | 0.011111 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.1.486 | 0.001577 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.128 | 0.000635 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.177.53 | 0.002392 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.177.82 | 0.000477 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.177.86 | 0.000183 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.240 | 0.000216 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.243 | 0.00007 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.258 | 0.000067 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.298 | 0.002114 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.349 | 0.000715 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.351 | 0.00003 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.36.7 | 0.004 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.396 | 0.000706 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.400 | 0.000429 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.429 | 0.000024 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.466.2 | 0.000391 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.527 | 0.003704 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.575 | 0.000303 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.576 | 0.000907 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.620 | 0.000946 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.621 | 0.000089 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.623 | 0.000536 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.630 | 0.005236 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.631 | 0.003367 |
N | 81 | D81D | gaT | gaC | 1 | 1 | B.1.637 | 0.000073 |
N | 81 | D81D | gaT | gaC | 1 | 1 | C.16 | 0.00106 |
N | 81 | D81D | gaT | gaC | 1 | 1 | N.9 | 0.005952 |
N | 81 | D81D | gaT | gaC | 1 | 1 | P.1.14 | 0.000048 |
N | 81 | D81D | gaT | gaC | 1 | 1 | Q.8 | 0.000165 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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