CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 6 | P6P | syn | ccC | ccT | 13407 | 12992 | 0.969046 | 28289-28291 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 6 | P6P | ccC | ccT | 12992 | 13407 | All | 0.002485 |
N | 6 | P6P | ccC | ccT | 6326 | 6378 | AY.4 | 0.009846 |
N | 6 | P6P | ccC | ccT | 1490 | 1491 | B.1.232 | 0.800645 |
N | 6 | P6P | ccC | ccT | 880 | 889 | B.1.1.7 | 0.000788 |
N | 6 | P6P | ccC | ccT | 532 | 532 | AY.34 | 0.051585 |
N | 6 | P6P | ccC | ccT | 225 | 446 | AY.44 | 0.00137 |
N | 6 | P6P | ccC | ccT | 314 | 330 | B.1.617.2 | 0.001182 |
N | 6 | P6P | ccC | ccT | 313 | 320 | B.1.2 | 0.002756 |
N | 6 | P6P | ccC | ccT | 235 | 235 | B.1.596 | 0.020478 |
N | 6 | P6P | ccC | ccT | 204 | 204 | B.1.526 | 0.004795 |
N | 6 | P6P | ccC | ccT | 163 | 173 | AY.43 | 0.000722 |
N | 6 | P6P | ccC | ccT | 161 | 161 | AY.25 | 0.000968 |
N | 6 | P6P | ccC | ccT | 136 | 145 | P.1 | 0.002143 |
N | 6 | P6P | ccC | ccT | 129 | 136 | AY.103 | 0.000801 |
N | 6 | P6P | ccC | ccT | 136 | 136 | B.1.1.413 | 0.937931 |
N | 6 | P6P | ccC | ccT | 113 | 122 | B.1 | 0.001035 |
N | 6 | P6P | ccC | ccT | 81 | 81 | B.1.1 | 0.001469 |
N | 6 | P6P | ccC | ccT | 74 | 77 | AY.39 | 0.001829 |
N | 6 | P6P | ccC | ccT | 73 | 73 | P.2 | 0.013624 |
N | 6 | P6P | ccC | ccT | 59 | 59 | AY.29 | 0.000931 |
N | 6 | P6P | ccC | ccT | 57 | 58 | AY.5 | 0.001177 |
N | 6 | P6P | ccC | ccT | 39 | 48 | AY.3 | 0.000388 |
N | 6 | P6P | ccC | ccT | 46 | 46 | B.1.234 | 0.006069 |
N | 6 | P6P | ccC | ccT | 40 | 42 | B.1.177 | 0.000527 |
N | 6 | P6P | ccC | ccT | 40 | 41 | B.1.351 | 0.001189 |
N | 6 | P6P | ccC | ccT | 38 | 38 | B.1.1.353 | 0.791667 |
N | 6 | P6P | ccC | ccT | 38 | 38 | B.1.243 | 0.002644 |
N | 6 | P6P | ccC | ccT | 35 | 35 | B.1.1.37 | 0.00675 |
N | 6 | P6P | ccC | ccT | 32 | 32 | AY.42 | 0.001287 |
N | 6 | P6P | ccC | ccT | 29 | 30 | B.1.160 | 0.000904 |
N | 6 | P6P | ccC | ccT | 29 | 29 | AY.121 | 0.003924 |
N | 6 | P6P | ccC | ccT | 12 | 29 | B.1.429 | 0.000282 |
N | 6 | P6P | ccC | ccT | 26 | 27 | AY.102 | 0.000689 |
N | 6 | P6P | ccC | ccT | 27 | 27 | AY.23 | 0.001883 |
N | 6 | P6P | ccC | ccT | 27 | 27 | AY.79 | 0.032688 |
N | 6 | P6P | ccC | ccT | 26 | 26 | B.1.1.432 | 0.032911 |
N | 6 | P6P | ccC | ccT | 24 | 24 | P.1.14 | 0.001147 |
N | 6 | P6P | ccC | ccT | 23 | 23 | AY.61 | 0.00241 |
N | 6 | P6P | ccC | ccT | 19 | 19 | AY.100 | 0.000874 |
N | 6 | P6P | ccC | ccT | 18 | 19 | AY.33 | 0.001202 |
N | 6 | P6P | ccC | ccT | 19 | 19 | AY.6 | 0.000781 |
N | 6 | P6P | ccC | ccT | 1 | 17 | B.1.1.222 | 0.000204 |
N | 6 | P6P | ccC | ccT | 17 | 17 | B.1.1.318 | 0.00513 |
N | 6 | P6P | ccC | ccT | 17 | 17 | B.1.146 | 0.072034 |
N | 6 | P6P | ccC | ccT | 16 | 16 | AY.119 | 0.000565 |
N | 6 | P6P | ccC | ccT | 16 | 16 | B.1.1.176 | 0.00703 |
N | 6 | P6P | ccC | ccT | 16 | 16 | B.1.36.38 | 0.026273 |
N | 6 | P6P | ccC | ccT | 16 | 16 | C.36.3 | 0.009075 |
N | 6 | P6P | ccC | ccT | 16 | 16 | P.1.16 | 0.005986 |
N | 6 | P6P | ccC | ccT | 14 | 15 | AY.26 | 0.000396 |
N | 6 | P6P | ccC | ccT | 15 | 15 | AY.62 | 0.006536 |
N | 6 | P6P | ccC | ccT | 10 | 14 | AY.4.2 | 0.000217 |
N | 6 | P6P | ccC | ccT | 14 | 14 | AY.9.1 | 0.001172 |
N | 6 | P6P | ccC | ccT | 14 | 14 | B.1.438.1 | 0.001502 |
N | 6 | P6P | ccC | ccT | 13 | 13 | A.2.5 | 0.006487 |
N | 6 | P6P | ccC | ccT | 13 | 13 | B.1.1.301 | 0.01533 |
N | 6 | P6P | ccC | ccT | 13 | 13 | B.1.1.306 | 0.005699 |
N | 6 | P6P | ccC | ccT | 12 | 13 | B.1.177.82 | 0.005728 |
N | 6 | P6P | ccC | ccT | 13 | 13 | P.1.15 | 0.00302 |
N | 6 | P6P | ccC | ccT | 12 | 12 | AY.113 | 0.001709 |
N | 6 | P6P | ccC | ccT | 12 | 12 | AY.9.2 | 0.000441 |
N | 6 | P6P | ccC | ccT | 11 | 12 | B.1.258.17 | 0.001144 |
N | 6 | P6P | ccC | ccT | 12 | 12 | Q.4 | 0.005457 |
N | 6 | P6P | ccC | ccT | 11 | 11 | AY.59 | 0.005826 |
N | 6 | P6P | ccC | ccT | 9 | 11 | AY.75 | 0.000504 |
N | 6 | P6P | ccC | ccT | 10 | 11 | B.1.1.519 | 0.000397 |
N | 6 | P6P | ccC | ccT | 11 | 11 | B.1.336 | 0.026829 |
N | 6 | P6P | ccC | ccT | 10 | 10 | AY.14 | 0.00088 |
N | 6 | P6P | ccC | ccT | 9 | 10 | AY.46 | 0.000937 |
N | 6 | P6P | ccC | ccT | 9 | 10 | B.1.258 | 0.000599 |
N | 6 | P6P | ccC | ccT | 9 | 9 | B.1.621 | 0.000797 |
N | 6 | P6P | ccC | ccT | 8 | 8 | AY.70 | 0.001668 |
N | 6 | P6P | ccC | ccT | 8 | 8 | B.1.1.316 | 0.007401 |
N | 6 | P6P | ccC | ccT | 7 | 7 | AY.120.1 | 0.002247 |
N | 6 | P6P | ccC | ccT | 4 | 7 | AY.20 | 0.000155 |
N | 6 | P6P | ccC | ccT | 7 | 7 | AY.4.5 | 0.000752 |
N | 6 | P6P | ccC | ccT | 7 | 7 | AY.46.4 | 0.001152 |
N | 6 | P6P | ccC | ccT | 7 | 7 | AY.88 | 0.006189 |
N | 6 | P6P | ccC | ccT | 6 | 6 | A.21 | 0.01662 |
N | 6 | P6P | ccC | ccT | 6 | 6 | AY.120 | 0.000223 |
N | 6 | P6P | ccC | ccT | 6 | 6 | AY.39.1 | 0.000238 |
N | 6 | P6P | ccC | ccT | 6 | 6 | AY.4.4 | 0.002455 |
N | 6 | P6P | ccC | ccT | 5 | 6 | AY.47 | 0.000156 |
N | 6 | P6P | ccC | ccT | 6 | 6 | D.2 | 0.00045 |
N | 6 | P6P | ccC | ccT | 5 | 5 | AY.110 | 0.000563 |
N | 6 | P6P | ccC | ccT | 5 | 5 | AY.41 | 0.00147 |
N | 6 | P6P | ccC | ccT | 5 | 5 | B.1.1.286 | 0.014493 |
N | 6 | P6P | ccC | ccT | 5 | 5 | B.1.36 | 0.00073 |
N | 6 | P6P | ccC | ccT | 5 | 5 | B.1.398 | 0.014881 |
N | 6 | P6P | ccC | ccT | 5 | 5 | B.1.404 | 0.00651 |
N | 6 | P6P | ccC | ccT | 4 | 5 | B.1.427 | 0.000202 |
N | 6 | P6P | ccC | ccT | 5 | 5 | B.1.466 | 0.116279 |
N | 6 | P6P | ccC | ccT | 5 | 5 | Q.8 | 0.000825 |
N | 6 | P6P | ccC | ccT | 5 | 5 | R.1 | 0.00045 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.117 | 0.000338 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.120.2.1 | 0.001993 |
N | 6 | P6P | ccC | ccT | 3 | 4 | AY.27 | 0.000194 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.3.1 | 0.000341 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.45 | 0.000487 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.5.4 | 0.001107 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.92 | 0.001149 |
N | 6 | P6P | ccC | ccT | 4 | 4 | AY.93 | 0.001092 |
N | 6 | P6P | ccC | ccT | 4 | 4 | B.1.1.214 | 0.000222 |
N | 6 | P6P | ccC | ccT | 4 | 4 | B.1.400 | 0.001716 |
N | 6 | P6P | ccC | ccT | 4 | 4 | B.1.637 | 0.000292 |
N | 6 | P6P | ccC | ccT | 3 | 3 | A.2 | 0.001985 |
N | 6 | P6P | ccC | ccT | 2 | 3 | AY.105 | 0.001286 |
N | 6 | P6P | ccC | ccT | 3 | 3 | AY.106 | 0.001005 |
N | 6 | P6P | ccC | ccT | 3 | 3 | AY.16.1 | 0.00141 |
N | 6 | P6P | ccC | ccT | 3 | 3 | AY.69 | 0.00056 |
N | 6 | P6P | ccC | ccT | 3 | 3 | AY.84 | 0.001312 |
N | 6 | P6P | ccC | ccT | 3 | 3 | AY.9 | 0.000203 |
N | 6 | P6P | ccC | ccT | 3 | 3 | B.1.1.28 | 0.000934 |
N | 6 | P6P | ccC | ccT | 3 | 3 | B.1.221 | 0.000213 |
N | 6 | P6P | ccC | ccT | 3 | 3 | B.1.420 | 0.03125 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.116 | 0.000574 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.46.2 | 0.001271 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.54 | 0.000191 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.63 | 0.000774 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.75.1 | 0.000361 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.87 | 0.001665 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.97 | 0.003401 |
N | 6 | P6P | ccC | ccT | 2 | 2 | AY.98.1 | 0.000097 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B | 0.000256 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.1.216 | 0.001781 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.1.348 | 0.001592 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.1.372 | 0.001377 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.1.50 | 0.001358 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.170 | 0.008621 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.177.81 | 0.000379 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.214.2 | 0.001199 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.240 | 0.000431 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.36.29 | 0.001035 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.466.2 | 0.000782 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.518 | 0.023529 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.524 | 0.002813 |
N | 6 | P6P | ccC | ccT | 2 | 2 | B.1.564.1 | 0.003155 |
N | 6 | P6P | ccC | ccT | 2 | 2 | Q.3 | 0.00029 |
N | 6 | P6P | ccC | ccT | 1 | 1 | A.23.1 | 0.000704 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.104 | 0.001984 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.109 | 0.00074 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.111 | 0.000183 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.114 | 0.000231 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.13 | 0.000161 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.19 | 0.00114 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.29.1 | 0.000221 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.30 | 0.000396 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.32 | 0.000532 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.34.1 | 0.00051 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.39.2 | 0.001541 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.4.3 | 0.000842 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.46.1 | 0.001027 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.53 | 0.000288 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.55 | 0.000917 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.68 | 0.000274 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.71 | 0.000475 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.72 | 0.001361 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.74 | 0.000116 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.8 | 0.000606 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.98 | 0.000079 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AY.99.2 | 0.000092 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AZ.1 | 0.000867 |
N | 6 | P6P | ccC | ccT | 1 | 1 | AZ.2 | 0.000821 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.16 | 0.055556 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.174 | 0.003378 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.244 | 0.015385 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.326 | 0.001761 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.33 | 0.000421 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.39 | 0.00051 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.409 | 0.002833 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.417 | 0.002703 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.434 | 0.000349 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.466 | 0.008696 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.1.99 | 0.02381 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.110.3 | 0.000718 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.157 | 0.002985 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.54 | 0.000606 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.55 | 0.002331 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.60 | 0.000218 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.63 | 0.002703 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.7 | 0.000165 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.177.77 | 0.000726 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.214 | 0.003663 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.237 | 0.004975 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.241 | 0.000812 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.260 | 0.003344 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.265 | 0.001271 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.284 | 0.013158 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.311 | 0.000275 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.349 | 0.000715 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.36.10 | 0.004785 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.36.18 | 0.00042 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.36.22 | 0.001208 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.36.7 | 0.004 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.36.8 | 0.001 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.361 | 0.001289 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.362 | 0.001541 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.369 | 0.000285 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.417 | 0.028571 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.422 | 0.000812 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.428 | 0.00102 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.438 | 0.006536 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.443 | 0.004673 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.460 | 0.017857 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.538 | 0.008065 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.564 | 0.000426 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.595 | 0.000261 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.605 | 0.005952 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.607 | 0.052632 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.617.1 | 0.000129 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.620 | 0.000946 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.621.1 | 0.000506 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.623 | 0.000536 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.626 | 0.005714 |
N | 6 | P6P | ccC | ccT | 1 | 1 | B.1.93 | 0.000934 |
N | 6 | P6P | ccC | ccT | 1 | 1 | C.11 | 0.010638 |
N | 6 | P6P | ccC | ccT | 1 | 1 | N.4 | 0.004255 |
N | 6 | P6P | ccC | ccT | 1 | 1 | P.1.12 | 0.000484 |
N | 6 | P6P | ccC | ccT | 1 | 1 | P.1.17 | 0.000162 |
N | 6 | P6P | ccC | ccT | 1 | 1 | P.1.7 | 0.000319 |
N | 6 | P6P | ccC | ccT | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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