CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 418 & Codon = caT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	418	Q418H		nonsyn	caG	caT	17987	17920	0.996275	29525-29527

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	418	Q418H	caG	caT	17920	17987	All	0.003427
N	418	Q418H	caG	caT	11103	11103	R.1	0.99937
N	418	Q418H	caG	caT	2130	2131	B.1.1.519	0.084584
N	418	Q418H	caG	caT	609	610	B.1.617.2	0.002293
N	418	Q418H	caG	caT	416	416	AY.75	0.023305
N	418	Q418H	caG	caT	320	321	B.1.2	0.002818
N	418	Q418H	caG	caT	314	314	AY.102	0.008325
N	418	Q418H	caG	caT	293	294	B.1.1.7	0.000262
N	418	Q418H	caG	caT	287	288	B.1.1	0.005206
N	418	Q418H	caG	caT	285	285	AY.98.1	0.013803
N	418	Q418H	caG	caT	280	280	B.1.1.214	0.015528
N	418	Q418H	caG	caT	182	183	B.1.351	0.00541
N	418	Q418H	caG	caT	159	159	AY.103	0.000987
N	418	Q418H	caG	caT	139	140	B.1.177	0.00183
N	418	Q418H	caG	caT	127	134	AY.4	0.000198
N	418	Q418H	caG	caT	116	118	B.1	0.001063
N	418	Q418H	caG	caT	103	103	B.1.1.220	0.19145
N	418	Q418H	caG	caT	79	79	AY.39	0.001952
N	418	Q418H	caG	caT	73	75	AY.43	0.000323
N	418	Q418H	caG	caT	43	43	B.1.575	0.013046
N	418	Q418H	caG	caT	33	34	AY.44	0.000201
N	418	Q418H	caG	caT	34	34	B.1.1.525	0.185792
N	418	Q418H	caG	caT	31	31	AY.3	0.000308
N	418	Q418H	caG	caT	14	31	AY.4.2	0.000304
N	418	Q418H	caG	caT	30	30	B.1.243	0.002088
N	418	Q418H	caG	caT	29	29	B.1.625	0.068235
N	418	Q418H	caG	caT	29	29	P.1	0.000457
N	418	Q418H	caG	caT	24	27	AY.25	0.000144
N	418	Q418H	caG	caT	26	27	AY.5	0.000537
N	418	Q418H	caG	caT	23	23	AY.120	0.000855
N	418	Q418H	caG	caT	22	22	AY.33	0.001469
N	418	Q418H	caG	caT	18	18	P.1.17.1	0.015748
N	418	Q418H	caG	caT	17	17	AY.119	0.0006
N	418	Q418H	caG	caT	17	17	AY.20	0.000661
N	418	Q418H	caG	caT	17	17	AY.9.2	0.000624
N	418	Q418H	caG	caT	17	17	B.1.1.317	0.006999
N	418	Q418H	caG	caT	16	16	B.1.596	0.001394
N	418	Q418H	caG	caT	15	15	AY.73	0.00998
N	418	Q418H	caG	caT	14	14	AY.98	0.001106
N	418	Q418H	caG	caT	13	13	AY.7.1	0.001465
N	418	Q418H	caG	caT	13	13	B.1.1.280	0.040123
N	418	Q418H	caG	caT	9	13	B.1.526	0.000212
N	418	Q418H	caG	caT	12	12	B.1.1.10	0.013378
N	418	Q418H	caG	caT	11	11	B.1.416	0.013959
N	418	Q418H	caG	caT	10	10	AY.29	0.000158
N	418	Q418H	caG	caT	10	10	AY.34	0.00097
N	418	Q418H	caG	caT	9	9	AY.117	0.000761
N	418	Q418H	caG	caT	9	9	AY.39.1	0.000357
N	418	Q418H	caG	caT	9	9	AY.47	0.00028
N	418	Q418H	caG	caT	9	9	B.1.258.3	0.015075
N	418	Q418H	caG	caT	3	8	AY.45	0.000365
N	418	Q418H	caG	caT	7	8	AY.46	0.000729
N	418	Q418H	caG	caT	8	8	AY.84	0.0035
N	418	Q418H	caG	caT	7	8	B.1.160	0.000218
N	418	Q418H	caG	caT	6	8	B.1.429	0.000141
N	418	Q418H	caG	caT	8	8	P.1.14	0.000382
N	418	Q418H	caG	caT	8	8	P.1.17	0.001294
N	418	Q418H	caG	caT	7	7	AY.100	0.000322
N	418	Q418H	caG	caT	7	7	B.1.1.222	0.001428
N	418	Q418H	caG	caT	7	7	B.1.177.77	0.005084
N	418	Q418H	caG	caT	7	7	B.1.177.85	0.038043
N	418	Q418H	caG	caT	6	6	AY.26	0.00017
N	418	Q418H	caG	caT	5	5	B.1.1.311	0.001791
N	418	Q418H	caG	caT	5	5	B.1.177.12	0.000758
N	418	Q418H	caG	caT	5	5	C.37	0.00058
N	418	Q418H	caG	caT	4	4	AY.4.4	0.001637
N	418	Q418H	caG	caT	4	4	AY.42	0.000161
N	418	Q418H	caG	caT	3	4	AY.6	0.000123
N	418	Q418H	caG	caT	4	4	AY.61	0.000419
N	418	Q418H	caG	caT	4	4	AY.99.2	0.000369
N	418	Q418H	caG	caT	4	4	B.1.1.216	0.003562
N	418	Q418H	caG	caT	3	3	A.2.5	0.001497
N	418	Q418H	caG	caT	3	3	AY.106	0.001005
N	418	Q418H	caG	caT	3	3	AY.23	0.000209
N	418	Q418H	caG	caT	3	3	AY.62	0.001307
N	418	Q418H	caG	caT	3	3	AY.75.1	0.000541
N	418	Q418H	caG	caT	3	3	B.1.1.161	0.010601
N	418	Q418H	caG	caT	3	3	B.1.1.318	0.000905
N	418	Q418H	caG	caT	3	3	B.1.1.37	0.000579
N	418	Q418H	caG	caT	3	3	B.1.1.39	0.001529
N	418	Q418H	caG	caT	3	3	B.1.1.521	0.016043
N	418	Q418H	caG	caT	3	3	B.1.1.83	0.00813
N	418	Q418H	caG	caT	3	3	B.1.351.2	0.000908
N	418	Q418H	caG	caT	3	3	B.1.351.3	0.002629
N	418	Q418H	caG	caT	3	3	B.1.525	0.000339
N	418	Q418H	caG	caT	2	3	B.1.577	0.001375
N	418	Q418H	caG	caT	3	3	B.1.621	0.000266
N	418	Q418H	caG	caT	3	3	B.1.621.1	0.001517
N	418	Q418H	caG	caT	3	3	B.1.637	0.000219
N	418	Q418H	caG	caT	3	3	B.1.9.1	0.096774
N	418	Q418H	caG	caT	3	3	P.1.15	0.000697
N	418	Q418H	caG	caT	2	2	A.23.1	0.001408
N	418	Q418H	caG	caT	2	2	AY.113	0.000285
N	418	Q418H	caG	caT	2	2	AY.14	0.000176
N	418	Q418H	caG	caT	2	2	AY.32	0.001065
N	418	Q418H	caG	caT	2	2	AY.37	0.000632
N	418	Q418H	caG	caT	2	2	AY.46.1	0.002053
N	418	Q418H	caG	caT	2	2	AY.5.3	0.000675
N	418	Q418H	caG	caT	2	2	AY.5.4	0.000553
N	418	Q418H	caG	caT	2	2	AY.54	0.000191
N	418	Q418H	caG	caT	2	2	AY.68	0.000547
N	418	Q418H	caG	caT	2	2	AY.9.1	0.000167
N	418	Q418H	caG	caT	2	2	AY.92	0.000575
N	418	Q418H	caG	caT	2	2	B.1.1.1	0.000653
N	418	Q418H	caG	caT	2	2	B.1.1.198	0.002937
N	418	Q418H	caG	caT	2	2	B.1.1.25	0.001137
N	418	Q418H	caG	caT	2	2	B.1.1.28	0.000622
N	418	Q418H	caG	caT	2	2	B.1.1.291	0.001485
N	418	Q418H	caG	caT	2	2	B.1.1.305	0.007722
N	418	Q418H	caG	caT	2	2	B.1.1.306	0.000877
N	418	Q418H	caG	caT	2	2	B.1.1.51	0.003436
N	418	Q418H	caG	caT	2	2	B.1.1.523	0.003125
N	418	Q418H	caG	caT	2	2	B.1.1.70	0.000682
N	418	Q418H	caG	caT	2	2	B.1.258	0.000133
N	418	Q418H	caG	caT	2	2	B.1.265	0.002541
N	418	Q418H	caG	caT	2	2	B.1.36.8	0.002
N	418	Q418H	caG	caT	2	2	B.1.396	0.001411
N	418	Q418H	caG	caT	2	2	B.1.503	0.004975
N	418	Q418H	caG	caT	2	2	B.1.575.1	0.004878
N	418	Q418H	caG	caT	2	2	B.1.595	0.000522
N	418	Q418H	caG	caT	2	2	B.1.617.1	0.000258
N	418	Q418H	caG	caT	2	2	C.16	0.002121
N	418	Q418H	caG	caT	2	2	L.3	0.007092
N	418	Q418H	caG	caT	2	2	P.2	0.000373
N	418	Q418H	caG	caT	2	2	Q.3	0.00029
N	418	Q418H	caG	caT	1	1	A.2.4	0.003367
N	418	Q418H	caG	caT	1	1	AE.8	0.000489
N	418	Q418H	caG	caT	1	1	AM.4	0.003571
N	418	Q418H	caG	caT	1	1	AU.3	0.00211
N	418	Q418H	caG	caT	1	1	AY.104	0.001984
N	418	Q418H	caG	caT	1	1	AY.116	0.000287
N	418	Q418H	caG	caT	1	1	AY.118	0.000063
N	418	Q418H	caG	caT	1	1	AY.15	0.002222
N	418	Q418H	caG	caT	1	1	AY.19	0.00114
N	418	Q418H	caG	caT	1	1	AY.3.1	0.000085
N	418	Q418H	caG	caT	1	1	AY.30	0.000396
N	418	Q418H	caG	caT	1	1	AY.34.1	0.00051
N	418	Q418H	caG	caT	1	1	AY.36	0.000148
N	418	Q418H	caG	caT	1	1	AY.4.3	0.000842
N	418	Q418H	caG	caT	1	1	AY.41	0.000294
N	418	Q418H	caG	caT	1	1	AY.46.3	0.000934
N	418	Q418H	caG	caT	1	1	AY.46.6	0.000072
N	418	Q418H	caG	caT	1	1	AY.64	0.000595
N	418	Q418H	caG	caT	1	1	AY.7	0.000196
N	418	Q418H	caG	caT	1	1	AY.82	0.001357
N	418	Q418H	caG	caT	1	1	AY.83	0.001724
N	418	Q418H	caG	caT	1	1	AY.9	0.000068
N	418	Q418H	caG	caT	1	1	B.1.1.196	0.005714
N	418	Q418H	caG	caT	1	1	B.1.1.221	0.010101
N	418	Q418H	caG	caT	1	1	B.1.1.232	0.001815
N	418	Q418H	caG	caT	1	1	B.1.1.236	0.006897
N	418	Q418H	caG	caT	1	1	B.1.1.261	0.008621
N	418	Q418H	caG	caT	1	1	B.1.1.263	0.001558
N	418	Q418H	caG	caT	1	1	B.1.1.277	0.000759
N	418	Q418H	caG	caT	1	1	B.1.1.284	0.000107
N	418	Q418H	caG	caT	1	1	B.1.1.300	0.010753
N	418	Q418H	caG	caT	1	1	B.1.1.33	0.000421
N	418	Q418H	caG	caT	1	1	B.1.1.416	0.000905
N	418	Q418H	caG	caT	1	1	B.1.1.419	0.007407
N	418	Q418H	caG	caT	1	1	B.1.1.46	0.004367
N	418	Q418H	caG	caT	1	1	B.1.1.464	0.001473
N	418	Q418H	caG	caT	1	1	B.1.1.522	0.017241
N	418	Q418H	caG	caT	1	1	B.1.1.526	0.003546
N	418	Q418H	caG	caT	1	1	B.1.1.8	0.003584
N	418	Q418H	caG	caT	1	1	B.1.161	0.017241
N	418	Q418H	caG	caT	1	1	B.1.177.4	0.000211
N	418	Q418H	caG	caT	1	1	B.1.177.56	0.000668
N	418	Q418H	caG	caT	1	1	B.1.177.57	0.000281
N	418	Q418H	caG	caT	1	1	B.1.177.60	0.000218
N	418	Q418H	caG	caT	1	1	B.1.177.65	0.000665
N	418	Q418H	caG	caT	1	1	B.1.177.75	0.001041
N	418	Q418H	caG	caT	1	1	B.1.177.81	0.000189
N	418	Q418H	caG	caT	1	1	B.1.177.84	0.006667
N	418	Q418H	caG	caT	1	1	B.1.177.86	0.000183
N	418	Q418H	caG	caT	1	1	B.1.195	0.005025
N	418	Q418H	caG	caT	1	1	B.1.221	0.000071
N	418	Q418H	caG	caT	1	1	B.1.234	0.000132
N	418	Q418H	caG	caT	1	1	B.1.260	0.003344
N	418	Q418H	caG	caT	1	1	B.1.298	0.002114
N	418	Q418H	caG	caT	1	1	B.1.324	0.001605
N	418	Q418H	caG	caT	1	1	B.1.36.10	0.004785
N	418	Q418H	caG	caT	1	1	B.1.36.18	0.00042
N	418	Q418H	caG	caT	1	1	B.1.36.29	0.000517
N	418	Q418H	caG	caT	1	1	B.1.369	0.000285
N	418	Q418H	caG	caT	1	1	B.1.389	0.001002
N	418	Q418H	caG	caT	1	1	B.1.427	0.00005
N	418	Q418H	caG	caT	1	1	B.1.428	0.00102
N	418	Q418H	caG	caT	1	1	B.1.468	0.005714
N	418	Q418H	caG	caT	1	1	B.1.470	0.001404
N	418	Q418H	caG	caT	1	1	B.1.524	0.001406
N	418	Q418H	caG	caT	1	1	B.1.561	0.000397
N	418	Q418H	caG	caT	1	1	B.1.568	0.001111
N	418	Q418H	caG	caT	1	1	B.1.606	0.006024
N	418	Q418H	caG	caT	1	1	B.1.609	0.000479
N	418	Q418H	caG	caT	1	1	B.1.628	0.000352
N	418	Q418H	caG	caT	1	1	B.11	0.005128
N	418	Q418H	caG	caT	1	1	C.1	0.002392
N	418	Q418H	caG	caT	1	1	C.36	0.000911
N	418	Q418H	caG	caT	1	1	D.2	0.000075
N	418	Q418H	caG	caT	1	1	P.1.12	0.000484
N	418	Q418H	caG	caT	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.