CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 418 | Q418H | nonsyn | caG | caT | 17987 | 17920 | 0.996275 | 29525-29527 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 418 | Q418H | caG | caT | 17920 | 17987 | All | 0.003427 |
N | 418 | Q418H | caG | caT | 11103 | 11103 | R.1 | 0.99937 |
N | 418 | Q418H | caG | caT | 2130 | 2131 | B.1.1.519 | 0.084584 |
N | 418 | Q418H | caG | caT | 609 | 610 | B.1.617.2 | 0.002293 |
N | 418 | Q418H | caG | caT | 416 | 416 | AY.75 | 0.023305 |
N | 418 | Q418H | caG | caT | 320 | 321 | B.1.2 | 0.002818 |
N | 418 | Q418H | caG | caT | 314 | 314 | AY.102 | 0.008325 |
N | 418 | Q418H | caG | caT | 293 | 294 | B.1.1.7 | 0.000262 |
N | 418 | Q418H | caG | caT | 287 | 288 | B.1.1 | 0.005206 |
N | 418 | Q418H | caG | caT | 285 | 285 | AY.98.1 | 0.013803 |
N | 418 | Q418H | caG | caT | 280 | 280 | B.1.1.214 | 0.015528 |
N | 418 | Q418H | caG | caT | 182 | 183 | B.1.351 | 0.00541 |
N | 418 | Q418H | caG | caT | 159 | 159 | AY.103 | 0.000987 |
N | 418 | Q418H | caG | caT | 139 | 140 | B.1.177 | 0.00183 |
N | 418 | Q418H | caG | caT | 127 | 134 | AY.4 | 0.000198 |
N | 418 | Q418H | caG | caT | 116 | 118 | B.1 | 0.001063 |
N | 418 | Q418H | caG | caT | 103 | 103 | B.1.1.220 | 0.19145 |
N | 418 | Q418H | caG | caT | 79 | 79 | AY.39 | 0.001952 |
N | 418 | Q418H | caG | caT | 73 | 75 | AY.43 | 0.000323 |
N | 418 | Q418H | caG | caT | 43 | 43 | B.1.575 | 0.013046 |
N | 418 | Q418H | caG | caT | 33 | 34 | AY.44 | 0.000201 |
N | 418 | Q418H | caG | caT | 34 | 34 | B.1.1.525 | 0.185792 |
N | 418 | Q418H | caG | caT | 31 | 31 | AY.3 | 0.000308 |
N | 418 | Q418H | caG | caT | 14 | 31 | AY.4.2 | 0.000304 |
N | 418 | Q418H | caG | caT | 30 | 30 | B.1.243 | 0.002088 |
N | 418 | Q418H | caG | caT | 29 | 29 | B.1.625 | 0.068235 |
N | 418 | Q418H | caG | caT | 29 | 29 | P.1 | 0.000457 |
N | 418 | Q418H | caG | caT | 24 | 27 | AY.25 | 0.000144 |
N | 418 | Q418H | caG | caT | 26 | 27 | AY.5 | 0.000537 |
N | 418 | Q418H | caG | caT | 23 | 23 | AY.120 | 0.000855 |
N | 418 | Q418H | caG | caT | 22 | 22 | AY.33 | 0.001469 |
N | 418 | Q418H | caG | caT | 18 | 18 | P.1.17.1 | 0.015748 |
N | 418 | Q418H | caG | caT | 17 | 17 | AY.119 | 0.0006 |
N | 418 | Q418H | caG | caT | 17 | 17 | AY.20 | 0.000661 |
N | 418 | Q418H | caG | caT | 17 | 17 | AY.9.2 | 0.000624 |
N | 418 | Q418H | caG | caT | 17 | 17 | B.1.1.317 | 0.006999 |
N | 418 | Q418H | caG | caT | 16 | 16 | B.1.596 | 0.001394 |
N | 418 | Q418H | caG | caT | 15 | 15 | AY.73 | 0.00998 |
N | 418 | Q418H | caG | caT | 14 | 14 | AY.98 | 0.001106 |
N | 418 | Q418H | caG | caT | 13 | 13 | AY.7.1 | 0.001465 |
N | 418 | Q418H | caG | caT | 13 | 13 | B.1.1.280 | 0.040123 |
N | 418 | Q418H | caG | caT | 9 | 13 | B.1.526 | 0.000212 |
N | 418 | Q418H | caG | caT | 12 | 12 | B.1.1.10 | 0.013378 |
N | 418 | Q418H | caG | caT | 11 | 11 | B.1.416 | 0.013959 |
N | 418 | Q418H | caG | caT | 10 | 10 | AY.29 | 0.000158 |
N | 418 | Q418H | caG | caT | 10 | 10 | AY.34 | 0.00097 |
N | 418 | Q418H | caG | caT | 9 | 9 | AY.117 | 0.000761 |
N | 418 | Q418H | caG | caT | 9 | 9 | AY.39.1 | 0.000357 |
N | 418 | Q418H | caG | caT | 9 | 9 | AY.47 | 0.00028 |
N | 418 | Q418H | caG | caT | 9 | 9 | B.1.258.3 | 0.015075 |
N | 418 | Q418H | caG | caT | 3 | 8 | AY.45 | 0.000365 |
N | 418 | Q418H | caG | caT | 7 | 8 | AY.46 | 0.000729 |
N | 418 | Q418H | caG | caT | 8 | 8 | AY.84 | 0.0035 |
N | 418 | Q418H | caG | caT | 7 | 8 | B.1.160 | 0.000218 |
N | 418 | Q418H | caG | caT | 6 | 8 | B.1.429 | 0.000141 |
N | 418 | Q418H | caG | caT | 8 | 8 | P.1.14 | 0.000382 |
N | 418 | Q418H | caG | caT | 8 | 8 | P.1.17 | 0.001294 |
N | 418 | Q418H | caG | caT | 7 | 7 | AY.100 | 0.000322 |
N | 418 | Q418H | caG | caT | 7 | 7 | B.1.1.222 | 0.001428 |
N | 418 | Q418H | caG | caT | 7 | 7 | B.1.177.77 | 0.005084 |
N | 418 | Q418H | caG | caT | 7 | 7 | B.1.177.85 | 0.038043 |
N | 418 | Q418H | caG | caT | 6 | 6 | AY.26 | 0.00017 |
N | 418 | Q418H | caG | caT | 5 | 5 | B.1.1.311 | 0.001791 |
N | 418 | Q418H | caG | caT | 5 | 5 | B.1.177.12 | 0.000758 |
N | 418 | Q418H | caG | caT | 5 | 5 | C.37 | 0.00058 |
N | 418 | Q418H | caG | caT | 4 | 4 | AY.4.4 | 0.001637 |
N | 418 | Q418H | caG | caT | 4 | 4 | AY.42 | 0.000161 |
N | 418 | Q418H | caG | caT | 3 | 4 | AY.6 | 0.000123 |
N | 418 | Q418H | caG | caT | 4 | 4 | AY.61 | 0.000419 |
N | 418 | Q418H | caG | caT | 4 | 4 | AY.99.2 | 0.000369 |
N | 418 | Q418H | caG | caT | 4 | 4 | B.1.1.216 | 0.003562 |
N | 418 | Q418H | caG | caT | 3 | 3 | A.2.5 | 0.001497 |
N | 418 | Q418H | caG | caT | 3 | 3 | AY.106 | 0.001005 |
N | 418 | Q418H | caG | caT | 3 | 3 | AY.23 | 0.000209 |
N | 418 | Q418H | caG | caT | 3 | 3 | AY.62 | 0.001307 |
N | 418 | Q418H | caG | caT | 3 | 3 | AY.75.1 | 0.000541 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.161 | 0.010601 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.318 | 0.000905 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.37 | 0.000579 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.39 | 0.001529 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.521 | 0.016043 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.1.83 | 0.00813 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.351.2 | 0.000908 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.351.3 | 0.002629 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.525 | 0.000339 |
N | 418 | Q418H | caG | caT | 2 | 3 | B.1.577 | 0.001375 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.621 | 0.000266 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.621.1 | 0.001517 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.637 | 0.000219 |
N | 418 | Q418H | caG | caT | 3 | 3 | B.1.9.1 | 0.096774 |
N | 418 | Q418H | caG | caT | 3 | 3 | P.1.15 | 0.000697 |
N | 418 | Q418H | caG | caT | 2 | 2 | A.23.1 | 0.001408 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.113 | 0.000285 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.14 | 0.000176 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.32 | 0.001065 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.37 | 0.000632 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.46.1 | 0.002053 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.5.3 | 0.000675 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.5.4 | 0.000553 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.54 | 0.000191 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.68 | 0.000547 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.9.1 | 0.000167 |
N | 418 | Q418H | caG | caT | 2 | 2 | AY.92 | 0.000575 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.1 | 0.000653 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.198 | 0.002937 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.25 | 0.001137 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.28 | 0.000622 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.291 | 0.001485 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.305 | 0.007722 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.306 | 0.000877 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.51 | 0.003436 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.523 | 0.003125 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.1.70 | 0.000682 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.258 | 0.000133 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.265 | 0.002541 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.36.8 | 0.002 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.396 | 0.001411 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.503 | 0.004975 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.575.1 | 0.004878 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.595 | 0.000522 |
N | 418 | Q418H | caG | caT | 2 | 2 | B.1.617.1 | 0.000258 |
N | 418 | Q418H | caG | caT | 2 | 2 | C.16 | 0.002121 |
N | 418 | Q418H | caG | caT | 2 | 2 | L.3 | 0.007092 |
N | 418 | Q418H | caG | caT | 2 | 2 | P.2 | 0.000373 |
N | 418 | Q418H | caG | caT | 2 | 2 | Q.3 | 0.00029 |
N | 418 | Q418H | caG | caT | 1 | 1 | A.2.4 | 0.003367 |
N | 418 | Q418H | caG | caT | 1 | 1 | AE.8 | 0.000489 |
N | 418 | Q418H | caG | caT | 1 | 1 | AM.4 | 0.003571 |
N | 418 | Q418H | caG | caT | 1 | 1 | AU.3 | 0.00211 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.104 | 0.001984 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.116 | 0.000287 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.118 | 0.000063 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.15 | 0.002222 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.19 | 0.00114 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.3.1 | 0.000085 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.30 | 0.000396 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.34.1 | 0.00051 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.36 | 0.000148 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.4.3 | 0.000842 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.41 | 0.000294 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.46.3 | 0.000934 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.46.6 | 0.000072 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.64 | 0.000595 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.7 | 0.000196 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.82 | 0.001357 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.83 | 0.001724 |
N | 418 | Q418H | caG | caT | 1 | 1 | AY.9 | 0.000068 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.196 | 0.005714 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.221 | 0.010101 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.232 | 0.001815 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.236 | 0.006897 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.261 | 0.008621 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.263 | 0.001558 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.277 | 0.000759 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.284 | 0.000107 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.300 | 0.010753 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.33 | 0.000421 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.416 | 0.000905 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.419 | 0.007407 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.46 | 0.004367 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.464 | 0.001473 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.522 | 0.017241 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.526 | 0.003546 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.1.8 | 0.003584 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.161 | 0.017241 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.4 | 0.000211 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.56 | 0.000668 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.57 | 0.000281 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.60 | 0.000218 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.65 | 0.000665 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.75 | 0.001041 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.81 | 0.000189 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.84 | 0.006667 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.177.86 | 0.000183 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.195 | 0.005025 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.221 | 0.000071 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.234 | 0.000132 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.260 | 0.003344 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.298 | 0.002114 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.324 | 0.001605 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.36.10 | 0.004785 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.36.18 | 0.00042 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.36.29 | 0.000517 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.369 | 0.000285 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.389 | 0.001002 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.427 | 0.00005 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.428 | 0.00102 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.468 | 0.005714 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.470 | 0.001404 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.524 | 0.001406 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.561 | 0.000397 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.568 | 0.001111 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.606 | 0.006024 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.609 | 0.000479 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.1.628 | 0.000352 |
N | 418 | Q418H | caG | caT | 1 | 1 | B.11 | 0.005128 |
N | 418 | Q418H | caG | caT | 1 | 1 | C.1 | 0.002392 |
N | 418 | Q418H | caG | caT | 1 | 1 | C.36 | 0.000911 |
N | 418 | Q418H | caG | caT | 1 | 1 | D.2 | 0.000075 |
N | 418 | Q418H | caG | caT | 1 | 1 | P.1.12 | 0.000484 |
N | 418 | Q418H | caG | caT | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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