CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 41 & Codon = Agg

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	41	R41R		syn	Cgg	Agg	21185	188	0.0088742	28394-28396

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	41	R41R	Cgg	Agg	188	21185	All	0.000036
N	41	R41R	Cgg	Agg	20	4470	B.1.1.7	0.000018
N	41	R41R	Cgg	Agg	2	4407	B.1.617.2	0.000008
N	41	R41R	Cgg	Agg	6	1244	AY.4	0.000009
N	41	R41R	Cgg	Agg	1	212	AY.39	0.000025
N	41	R41R	Cgg	Agg	1	164	B.1.1	0.000018
N	41	R41R	Cgg	Agg	5	147	AY.75	0.00028
N	41	R41R	Cgg	Agg	2	121	AY.43	0.000009
N	41	R41R	Cgg	Agg	3	121	AY.44	0.000018
N	41	R41R	Cgg	Agg	1	94	AY.102	0.000027
N	41	R41R	Cgg	Agg	1	89	AY.33	0.000067
N	41	R41R	Cgg	Agg	4	77	B.1	0.000037
N	41	R41R	Cgg	Agg	2	75	AY.103	0.000012
N	41	R41R	Cgg	Agg	22	70	B.1.2	0.000194
N	41	R41R	Cgg	Agg	54	58	B.1.526	0.001269
N	41	R41R	Cgg	Agg	1	57	P.1	0.000016
N	41	R41R	Cgg	Agg	1	42	AY.3	0.00001
N	41	R41R	Cgg	Agg	7	37	AY.45	0.000852
N	41	R41R	Cgg	Agg	9	34	AY.20	0.00035
N	41	R41R	Cgg	Agg	2	17	AY.110	0.000225
N	41	R41R	Cgg	Agg	1	14	B.1.1.519	0.00004
N	41	R41R	Cgg	Agg	1	14	B.1.243	0.00007
N	41	R41R	Cgg	Agg	1	12	AY.9.2	0.000037
N	41	R41R	Cgg	Agg	5	10	B.1.160	0.000156
N	41	R41R	Cgg	Agg	9	9	B.1.409	0.007031
N	41	R41R	Cgg	Agg	1	8	AY.26	0.000028
N	41	R41R	Cgg	Agg	2	8	B	0.000256
N	41	R41R	Cgg	Agg	2	8	P.1.17	0.000324
N	41	R41R	Cgg	Agg	1	7	B.1.351	0.00003
N	41	R41R	Cgg	Agg	2	6	AY.47	0.000062
N	41	R41R	Cgg	Agg	5	6	B.1.221	0.000355
N	41	R41R	Cgg	Agg	3	5	B.1.36	0.000438
N	41	R41R	Cgg	Agg	1	4	AY.52	0.000814
N	41	R41R	Cgg	Agg	1	4	AY.67	0.000464
N	41	R41R	Cgg	Agg	1	4	B.1.1.25	0.000569
N	41	R41R	Cgg	Agg	1	2	B.1.177.81	0.000189
N	41	R41R	Cgg	Agg	2	2	B.1.575	0.000607
N	41	R41R	Cgg	Agg	1	2	P.1.14	0.000048
N	41	R41R	Cgg	Agg	1	1	B.1.1.419	0.007407
N	41	R41R	Cgg	Agg	1	1	B.1.1.70	0.000341
N	41	R41R	Cgg	Agg	1	1	B.1.177.8	0.000752
N	41	R41R	Cgg	Agg	1	1	B.1.473	0.019231

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.