CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 373 & Codon = aaT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	373	K373N		nonsyn	aaG	aaT	18852	18134	0.961914	29390-29392

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	373	K373N	aaG	aaT	18134	18852	All	0.003468
N	373	K373N	aaG	aaT	8043	8043	AY.74	0.930149
N	373	K373N	aaG	aaT	1868	1908	B.1.617.2	0.007034
N	373	K373N	aaG	aaT	1767	1810	AY.103	0.010971
N	373	K373N	aaG	aaT	1289	1366	AY.4	0.002006
N	373	K373N	aaG	aaT	619	841	B.1.1.7	0.000554
N	373	K373N	aaG	aaT	391	400	AY.46	0.040695
N	373	K373N	aaG	aaT	377	392	AY.44	0.002295
N	373	K373N	aaG	aaT	367	391	AY.43	0.001626
N	373	K373N	aaG	aaT	349	361	AY.102	0.009253
N	373	K373N	aaG	aaT	317	317	B.1.177.65	0.210912
N	373	K373N	aaG	aaT	234	234	AY.9.2	0.008595
N	373	K373N	aaG	aaT	226	226	AY.86	0.187552
N	373	K373N	aaG	aaT	157	157	AY.98	0.012402
N	373	K373N	aaG	aaT	113	118	AY.25	0.00068
N	373	K373N	aaG	aaT	106	110	AY.119	0.003743
N	373	K373N	aaG	aaT	90	91	AY.39	0.002224
N	373	K373N	aaG	aaT	53	90	B.1	0.000485
N	373	K373N	aaG	aaT	81	88	B.1.2	0.000713
N	373	K373N	aaG	aaT	82	87	AY.3	0.000816
N	373	K373N	aaG	aaT	75	75	AY.107	0.034949
N	373	K373N	aaG	aaT	9	70	AY.47	0.00028
N	373	K373N	aaG	aaT	55	55	AY.7.1	0.006199
N	373	K373N	aaG	aaT	46	46	AY.120.1	0.014767
N	373	K373N	aaG	aaT	41	42	AY.98.1	0.001986
N	373	K373N	aaG	aaT	37	41	B.1.1	0.000671
N	373	K373N	aaG	aaT	39	40	B.1.234	0.005146
N	373	K373N	aaG	aaT	40	40	B.1.517	0.017079
N	373	K373N	aaG	aaT	38	39	AY.46.4	0.006251
N	373	K373N	aaG	aaT	26	38	P.1	0.00041
N	373	K373N	aaG	aaT	37	37	AY.21	0.070209
N	373	K373N	aaG	aaT	37	37	AY.39.1.1	0.026812
N	373	K373N	aaG	aaT	37	37	AY.4.5	0.003977
N	373	K373N	aaG	aaT	35	36	AY.45	0.004259
N	373	K373N	aaG	aaT	34	35	AY.5	0.000702
N	373	K373N	aaG	aaT	26	31	AY.6	0.001069
N	373	K373N	aaG	aaT	22	26	AY.20	0.000855
N	373	K373N	aaG	aaT	22	26	AY.29	0.000347
N	373	K373N	aaG	aaT	24	25	AY.4.2	0.000521
N	373	K373N	aaG	aaT	21	25	AY.42	0.000845
N	373	K373N	aaG	aaT	23	24	AY.120	0.000855
N	373	K373N	aaG	aaT	21	24	AY.26	0.000595
N	373	K373N	aaG	aaT	22	23	AY.33	0.001469
N	373	K373N	aaG	aaT	22	23	B.1.36	0.00321
N	373	K373N	aaG	aaT	19	23	B.1.526	0.000447
N	373	K373N	aaG	aaT	17	19	AY.100	0.000782
N	373	K373N	aaG	aaT	15	19	AY.117	0.001268
N	373	K373N	aaG	aaT	3	19	AY.39.1	0.000119
N	373	K373N	aaG	aaT	18	18	AY.46.6	0.0013
N	373	K373N	aaG	aaT	18	18	P.1.1	0.005718
N	373	K373N	aaG	aaT	17	17	AY.35	0.003962
N	373	K373N	aaG	aaT	13	17	AY.5.3	0.004386
N	373	K373N	aaG	aaT	17	17	B.1.1.257	0.165049
N	373	K373N	aaG	aaT	16	16	AY.9	0.001082
N	373	K373N	aaG	aaT	14	15	AY.106	0.004689
N	373	K373N	aaG	aaT	15	15	AY.23.1	0.00626
N	373	K373N	aaG	aaT	14	14	AY.24	0.006034
N	373	K373N	aaG	aaT	13	13	AY.118	0.000814
N	373	K373N	aaG	aaT	12	13	B.1.1.519	0.000477
N	373	K373N	aaG	aaT	11	13	B.1.160	0.000343
N	373	K373N	aaG	aaT	7	13	B.1.177	0.000092
N	373	K373N	aaG	aaT	13	13	B.1.177.4	0.002744
N	373	K373N	aaG	aaT	13	13	B.1.243	0.000905
N	373	K373N	aaG	aaT	10	13	B.1.351	0.000297
N	373	K373N	aaG	aaT	11	13	B.1.429	0.000259
N	373	K373N	aaG	aaT	12	12	B.1.1.50	0.008147
N	373	K373N	aaG	aaT	11	11	AY.113	0.001566
N	373	K373N	aaG	aaT	11	11	AY.114	0.002542
N	373	K373N	aaG	aaT	10	11	AY.23	0.000697
N	373	K373N	aaG	aaT	11	11	AY.54	0.001049
N	373	K373N	aaG	aaT	11	11	AY.84	0.004812
N	373	K373N	aaG	aaT	10	10	AY.104	0.019841
N	373	K373N	aaG	aaT	8	10	AY.27	0.000518
N	373	K373N	aaG	aaT	10	10	AY.34	0.00097
N	373	K373N	aaG	aaT	9	10	AY.46.2	0.005718
N	373	K373N	aaG	aaT	8	10	AY.75	0.000448
N	373	K373N	aaG	aaT	7	10	AY.99.2	0.000645
N	373	K373N	aaG	aaT	9	9	AY.75.1	0.001623
N	373	K373N	aaG	aaT	9	9	AY.90	0.00616
N	373	K373N	aaG	aaT	5	9	B.1.617.1	0.000645
N	373	K373N	aaG	aaT	8	8	AY.121	0.001083
N	373	K373N	aaG	aaT	7	8	AY.3.1	0.000597
N	373	K373N	aaG	aaT	8	8	B.1.1.222	0.001632
N	373	K373N	aaG	aaT	7	8	B.1.438.1	0.000751
N	373	K373N	aaG	aaT	7	7	AY.116	0.002007
N	373	K373N	aaG	aaT	7	7	AY.36	0.001037
N	373	K373N	aaG	aaT	7	7	AY.41	0.002058
N	373	K373N	aaG	aaT	7	7	AY.51	0.006364
N	373	K373N	aaG	aaT	7	7	AY.53	0.002013
N	373	K373N	aaG	aaT	6	7	AY.78	0.009245
N	373	K373N	aaG	aaT	7	7	B.1.351.3	0.006135
N	373	K373N	aaG	aaT	2	7	B.1.36.17	0.000988
N	373	K373N	aaG	aaT	7	7	C.37	0.000812
N	373	K373N	aaG	aaT	6	6	AY.116.1	0.001869
N	373	K373N	aaG	aaT	6	6	AY.34.1	0.00306
N	373	K373N	aaG	aaT	6	6	AY.56	0.009631
N	373	K373N	aaG	aaT	6	6	AY.59	0.003178
N	373	K373N	aaG	aaT	6	6	AY.61	0.000629
N	373	K373N	aaG	aaT	6	6	B.1.1.284	0.000644
N	373	K373N	aaG	aaT	5	5	AY.5.4	0.001384
N	373	K373N	aaG	aaT	5	5	AY.71	0.002375
N	373	K373N	aaG	aaT	5	5	AY.9.1	0.000419
N	373	K373N	aaG	aaT	5	5	B.1.400	0.002145
N	373	K373N	aaG	aaT	2	5	R.1	0.00018
N	373	K373N	aaG	aaT	4	4	AY.108	0.00441
N	373	K373N	aaG	aaT	4	4	AY.13	0.000644
N	373	K373N	aaG	aaT	4	4	AY.46.1	0.004107
N	373	K373N	aaG	aaT	4	4	AY.48	0.00186
N	373	K373N	aaG	aaT	4	4	AY.55	0.00367
N	373	K373N	aaG	aaT	4	4	AY.64	0.002381
N	373	K373N	aaG	aaT	4	4	AY.8	0.002424
N	373	K373N	aaG	aaT	4	4	AY.88	0.003537
N	373	K373N	aaG	aaT	4	4	B.1.1.312	0.007648
N	373	K373N	aaG	aaT	2	4	B.1.1.434	0.000697
N	373	K373N	aaG	aaT	3	4	B.1.258	0.0002
N	373	K373N	aaG	aaT	4	4	B.1.427	0.000202
N	373	K373N	aaG	aaT	4	4	B.1.609	0.001918
N	373	K373N	aaG	aaT	4	4	B.1.637	0.000292
N	373	K373N	aaG	aaT	2	3	AY.12	0.000632
N	373	K373N	aaG	aaT	1	3	AY.16.1	0.00047
N	373	K373N	aaG	aaT	3	3	AY.58	0.002722
N	373	K373N	aaG	aaT	3	3	AY.62	0.001307
N	373	K373N	aaG	aaT	3	3	AY.65	0.001599
N	373	K373N	aaG	aaT	3	3	AY.67	0.001393
N	373	K373N	aaG	aaT	3	3	AY.73	0.001996
N	373	K373N	aaG	aaT	3	3	AY.92	0.000862
N	373	K373N	aaG	aaT	3	3	B.1.1.214	0.000166
N	373	K373N	aaG	aaT	3	3	B.1.1.275	0.033708
N	373	K373N	aaG	aaT	2	3	B.1.1.28	0.000622
N	373	K373N	aaG	aaT	3	3	B.1.177.60	0.000655
N	373	K373N	aaG	aaT	3	3	B.1.177.73	0.001699
N	373	K373N	aaG	aaT	3	3	B.1.36.18	0.001261
N	373	K373N	aaG	aaT	2	3	B.1.409	0.001563
N	373	K373N	aaG	aaT	2	3	B.1.499	0.002101
N	373	K373N	aaG	aaT	2	3	B.1.525	0.000226
N	373	K373N	aaG	aaT	3	3	C.16	0.003181
N	373	K373N	aaG	aaT	3	3	P.1.14	0.000143
N	373	K373N	aaG	aaT	3	3	P.1.7	0.000958
N	373	K373N	aaG	aaT	3	3	Q.1	0.000379
N	373	K373N	aaG	aaT	2	2	A	0.000774
N	373	K373N	aaG	aaT	2	2	AE.8	0.000978
N	373	K373N	aaG	aaT	2	2	AY.101	0.000981
N	373	K373N	aaG	aaT	2	2	AY.105	0.001286
N	373	K373N	aaG	aaT	2	2	AY.109	0.001479
N	373	K373N	aaG	aaT	2	2	AY.111	0.000366
N	373	K373N	aaG	aaT	1	2	AY.16	0.00038
N	373	K373N	aaG	aaT	2	2	AY.29.1	0.000441
N	373	K373N	aaG	aaT	1	2	AY.46.5	0.000198
N	373	K373N	aaG	aaT	2	2	AY.68	0.000547
N	373	K373N	aaG	aaT	2	2	AY.7	0.000392
N	373	K373N	aaG	aaT	2	2	AY.72	0.002721
N	373	K373N	aaG	aaT	2	2	AY.83	0.003448
N	373	K373N	aaG	aaT	2	2	AY.85	0.000854
N	373	K373N	aaG	aaT	2	2	AY.91.1	0.00813
N	373	K373N	aaG	aaT	2	2	AY.93	0.000546
N	373	K373N	aaG	aaT	2	2	AY.94	0.000885
N	373	K373N	aaG	aaT	1	2	B	0.000128
N	373	K373N	aaG	aaT	1	2	B.1.1.25	0.000569
N	373	K373N	aaG	aaT	2	2	B.1.1.26	0.010471
N	373	K373N	aaG	aaT	2	2	B.1.1.398	0.006452
N	373	K373N	aaG	aaT	2	2	B.1.1.83	0.00542
N	373	K373N	aaG	aaT	2	2	B.1.240	0.000431
N	373	K373N	aaG	aaT	2	2	B.1.351.2	0.000605
N	373	K373N	aaG	aaT	2	2	B.1.416	0.002538
N	373	K373N	aaG	aaT	2	2	B.1.506	0.047619
N	373	K373N	aaG	aaT	2	2	B.1.538	0.016129
N	373	K373N	aaG	aaT	2	2	B.1.596	0.000174
N	373	K373N	aaG	aaT	2	2	B.1.628	0.000705
N	373	K373N	aaG	aaT	2	2	C.3	0.015267
N	373	K373N	aaG	aaT	2	2	D.2	0.00015
N	373	K373N	aaG	aaT	2	2	N.4	0.008511
N	373	K373N	aaG	aaT	1	2	P.1.16	0.000374
N	373	K373N	aaG	aaT	2	2	P.1.17	0.000324
N	373	K373N	aaG	aaT	2	2	P.7	0.008734
N	373	K373N	aaG	aaT	1	1	A.2.5.1	0.004808
N	373	K373N	aaG	aaT	1	1	AY.1	0.000396
N	373	K373N	aaG	aaT	1	1	AY.110	0.000113
N	373	K373N	aaG	aaT	1	1	AY.17	0.008197
N	373	K373N	aaG	aaT	1	1	AY.30	0.000396
N	373	K373N	aaG	aaT	1	1	AY.38	0.000499
N	373	K373N	aaG	aaT	1	1	AY.4.1	0.000737
N	373	K373N	aaG	aaT	1	1	AY.4.3	0.000842
N	373	K373N	aaG	aaT	1	1	AY.5.1	0.003759
N	373	K373N	aaG	aaT	1	1	AY.52	0.000814
N	373	K373N	aaG	aaT	1	1	AY.57	0.000656
N	373	K373N	aaG	aaT	1	1	AY.60	0.000938
N	373	K373N	aaG	aaT	1	1	AY.69	0.000187
N	373	K373N	aaG	aaT	1	1	AY.7.2	0.000559
N	373	K373N	aaG	aaT	1	1	AY.70	0.000209
N	373	K373N	aaG	aaT	1	1	AY.87	0.000833
N	373	K373N	aaG	aaT	1	1	AY.91	0.00073
N	373	K373N	aaG	aaT	1	1	AY.96	0.002075
N	373	K373N	aaG	aaT	1	1	AY.99	0.001049
N	373	K373N	aaG	aaT	1	1	B.1.1.1	0.000327
N	373	K373N	aaG	aaT	1	1	B.1.1.141	0.002012
N	373	K373N	aaG	aaT	1	1	B.1.1.186	0.003436
N	373	K373N	aaG	aaT	1	1	B.1.1.191	0.004762
N	373	K373N	aaG	aaT	1	1	B.1.1.207	0.001182
N	373	K373N	aaG	aaT	1	1	B.1.1.263	0.001558
N	373	K373N	aaG	aaT	1	1	B.1.1.306	0.000438
N	373	K373N	aaG	aaT	1	1	B.1.1.333	0.001076
N	373	K373N	aaG	aaT	1	1	B.1.1.348	0.000796
N	373	K373N	aaG	aaT	1	1	B.1.1.372	0.000689
N	373	K373N	aaG	aaT	1	1	B.1.1.397	0.002252
N	373	K373N	aaG	aaT	1	1	B.1.1.462	0.008621
N	373	K373N	aaG	aaT	1	1	B.1.1.54	0.003021
N	373	K373N	aaG	aaT	1	1	B.1.1.99	0.02381
N	373	K373N	aaG	aaT	1	1	B.1.14	0.017544
N	373	K373N	aaG	aaT	1	1	B.1.177.12	0.000152
N	373	K373N	aaG	aaT	1	1	B.1.177.56	0.000668
N	373	K373N	aaG	aaT	1	1	B.1.177.83	0.001481
N	373	K373N	aaG	aaT	1	1	B.1.177.9	0.001332
N	373	K373N	aaG	aaT	1	1	B.1.22	0.001318
N	373	K373N	aaG	aaT	1	1	B.1.221	0.000071
N	373	K373N	aaG	aaT	1	1	B.1.236	0.002053
N	373	K373N	aaG	aaT	1	1	B.1.241	0.000812
N	373	K373N	aaG	aaT	1	1	B.1.258.17	0.000104
N	373	K373N	aaG	aaT	1	1	B.1.258.19	0.007092
N	373	K373N	aaG	aaT	1	1	B.1.316	0.111111
N	373	K373N	aaG	aaT	1	1	B.1.320	0.001245
N	373	K373N	aaG	aaT	1	1	B.1.332	0.003497
N	373	K373N	aaG	aaT	1	1	B.1.351.5	0.0006
N	373	K373N	aaG	aaT	1	1	B.1.36.29	0.000517
N	373	K373N	aaG	aaT	1	1	B.1.36.36	0.000602
N	373	K373N	aaG	aaT	1	1	B.1.402	0.009804
N	373	K373N	aaG	aaT	1	1	B.1.428.3	0.012821
N	373	K373N	aaG	aaT	1	1	B.1.460	0.017857
N	373	K373N	aaG	aaT	1	1	B.1.523	0.002451
N	373	K373N	aaG	aaT	1	1	B.1.561	0.000397
N	373	K373N	aaG	aaT	1	1	B.1.565	0.00081
N	373	K373N	aaG	aaT	1	1	B.1.575	0.000303
N	373	K373N	aaG	aaT	1	1	B.1.599	0.00365
N	373	K373N	aaG	aaT	1	1	B.1.619.1	0.000641
N	373	K373N	aaG	aaT	1	1	B.1.620	0.000946
N	373	K373N	aaG	aaT	1	1	B.1.621	0.000089
N	373	K373N	aaG	aaT	1	1	B.1.9.5	0.005682
N	373	K373N	aaG	aaT	1	1	B.3	0.000831
N	373	K373N	aaG	aaT	1	1	B.55	0.00295
N	373	K373N	aaG	aaT	1	1	P.1.10	0.000269
N	373	K373N	aaG	aaT	1	1	P.1.12	0.000484
N	373	K373N	aaG	aaT	1	1	P.1.15	0.000232
N	373	K373N	aaG	aaT	1	1	P.1.17.1	0.000875
N	373	K373N	aaG	aaT	1	1	Q.3	0.000145
N	373	K373N	aaG	aaT	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.