CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 35 | A35A | syn | gcG | gcC | 30162 | 3856 | 0.127843 | 28376-28378 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 35 | A35A | gcG | gcC | 3856 | 30162 | All | 0.000738 |
N | 35 | A35A | gcG | gcC | 51 | 4205 | B.1.617.2 | 0.000192 |
N | 35 | A35A | gcG | gcC | 1162 | 4190 | AY.4 | 0.001809 |
N | 35 | A35A | gcG | gcC | 107 | 3084 | B.1.1.7 | 0.000096 |
N | 35 | A35A | gcG | gcC | 1411 | 1411 | A.23.1 | 0.993662 |
N | 35 | A35A | gcG | gcC | 3 | 1063 | AY.43 | 0.000013 |
N | 35 | A35A | gcG | gcC | 10 | 1028 | AY.102 | 0.000265 |
N | 35 | A35A | gcG | gcC | 6 | 499 | B.1.177 | 0.000079 |
N | 35 | A35A | gcG | gcC | 113 | 427 | B.1.2 | 0.000995 |
N | 35 | A35A | gcG | gcC | 25 | 400 | AY.39 | 0.000618 |
N | 35 | A35A | gcG | gcC | 142 | 390 | P.1 | 0.002237 |
N | 35 | A35A | gcG | gcC | 3 | 348 | AY.98.1 | 0.000145 |
N | 35 | A35A | gcG | gcC | 56 | 327 | B.1 | 0.000513 |
N | 35 | A35A | gcG | gcC | 11 | 302 | AY.103 | 0.000068 |
N | 35 | A35A | gcG | gcC | 17 | 293 | AY.44 | 0.000103 |
N | 35 | A35A | gcG | gcC | 24 | 245 | AY.25 | 0.000144 |
N | 35 | A35A | gcG | gcC | 24 | 162 | AY.61 | 0.002515 |
N | 35 | A35A | gcG | gcC | 3 | 150 | B.1.1.306 | 0.001315 |
N | 35 | A35A | gcG | gcC | 3 | 148 | AY.3 | 0.00003 |
N | 35 | A35A | gcG | gcC | 11 | 137 | B.1.526 | 0.000259 |
N | 35 | A35A | gcG | gcC | 55 | 126 | B.1.1 | 0.000998 |
N | 35 | A35A | gcG | gcC | 8 | 124 | B.1.1.519 | 0.000318 |
N | 35 | A35A | gcG | gcC | 123 | 123 | B.1.1.301 | 0.145047 |
N | 35 | A35A | gcG | gcC | 5 | 119 | AY.98 | 0.000395 |
N | 35 | A35A | gcG | gcC | 95 | 109 | B.1.177.7 | 0.015661 |
N | 35 | A35A | gcG | gcC | 7 | 108 | B.1.258.17 | 0.000728 |
N | 35 | A35A | gcG | gcC | 3 | 107 | AY.29 | 0.000047 |
N | 35 | A35A | gcG | gcC | 7 | 95 | B.1.1.222 | 0.001428 |
N | 35 | A35A | gcG | gcC | 93 | 93 | A.23 | 0.978947 |
N | 35 | A35A | gcG | gcC | 9 | 85 | AY.117 | 0.000761 |
N | 35 | A35A | gcG | gcC | 17 | 83 | B.1.36 | 0.00248 |
N | 35 | A35A | gcG | gcC | 6 | 75 | AY.46 | 0.000624 |
N | 35 | A35A | gcG | gcC | 1 | 72 | AY.5 | 0.000021 |
N | 35 | A35A | gcG | gcC | 15 | 66 | AY.26 | 0.000425 |
N | 35 | A35A | gcG | gcC | 6 | 66 | B.1.160 | 0.000187 |
N | 35 | A35A | gcG | gcC | 1 | 58 | AY.36 | 0.000148 |
N | 35 | A35A | gcG | gcC | 5 | 54 | AY.20 | 0.000194 |
N | 35 | A35A | gcG | gcC | 2 | 53 | AY.120 | 0.000074 |
N | 35 | A35A | gcG | gcC | 2 | 53 | AY.42 | 0.00008 |
N | 35 | A35A | gcG | gcC | 3 | 52 | B.1.258 | 0.0002 |
N | 35 | A35A | gcG | gcC | 3 | 51 | AY.100 | 0.000138 |
N | 35 | A35A | gcG | gcC | 9 | 51 | AY.119 | 0.000318 |
N | 35 | A35A | gcG | gcC | 3 | 44 | AY.69 | 0.00056 |
N | 35 | A35A | gcG | gcC | 2 | 39 | AY.113 | 0.000285 |
N | 35 | A35A | gcG | gcC | 2 | 39 | AY.45 | 0.000243 |
N | 35 | A35A | gcG | gcC | 3 | 38 | AY.92 | 0.000862 |
N | 35 | A35A | gcG | gcC | 5 | 37 | AY.33 | 0.000334 |
N | 35 | A35A | gcG | gcC | 2 | 35 | B.1.609 | 0.000959 |
N | 35 | A35A | gcG | gcC | 1 | 34 | AY.4.2 | 0.000022 |
N | 35 | A35A | gcG | gcC | 3 | 31 | P.1.14 | 0.000143 |
N | 35 | A35A | gcG | gcC | 1 | 29 | AY.23 | 0.00007 |
N | 35 | A35A | gcG | gcC | 10 | 27 | AY.47 | 0.000311 |
N | 35 | A35A | gcG | gcC | 1 | 27 | AY.9 | 0.000068 |
N | 35 | A35A | gcG | gcC | 1 | 23 | B | 0.000128 |
N | 35 | A35A | gcG | gcC | 11 | 22 | A | 0.004257 |
N | 35 | A35A | gcG | gcC | 2 | 22 | R.1 | 0.00018 |
N | 35 | A35A | gcG | gcC | 2 | 21 | B.1.427 | 0.000101 |
N | 35 | A35A | gcG | gcC | 2 | 20 | AY.84 | 0.000875 |
N | 35 | A35A | gcG | gcC | 14 | 20 | B.1.1.216 | 0.012467 |
N | 35 | A35A | gcG | gcC | 2 | 19 | AY.121 | 0.000271 |
N | 35 | A35A | gcG | gcC | 3 | 18 | AY.99.2 | 0.000276 |
N | 35 | A35A | gcG | gcC | 7 | 17 | AY.5.3 | 0.002362 |
N | 35 | A35A | gcG | gcC | 2 | 15 | B.1.525 | 0.000226 |
N | 35 | A35A | gcG | gcC | 5 | 13 | B.1.1.28 | 0.001556 |
N | 35 | A35A | gcG | gcC | 5 | 12 | AY.120.1 | 0.001605 |
N | 35 | A35A | gcG | gcC | 1 | 12 | Q.8 | 0.000165 |
N | 35 | A35A | gcG | gcC | 6 | 11 | B.1.1.1 | 0.00196 |
N | 35 | A35A | gcG | gcC | 2 | 10 | AY.110 | 0.000225 |
N | 35 | A35A | gcG | gcC | 1 | 10 | AY.46.4 | 0.000165 |
N | 35 | A35A | gcG | gcC | 7 | 10 | AY.59 | 0.003708 |
N | 35 | A35A | gcG | gcC | 4 | 10 | AY.89 | 0.019608 |
N | 35 | A35A | gcG | gcC | 1 | 10 | C.37 | 0.000116 |
N | 35 | A35A | gcG | gcC | 3 | 9 | AY.4.4 | 0.001227 |
N | 35 | A35A | gcG | gcC | 2 | 9 | AY.7.1 | 0.000225 |
N | 35 | A35A | gcG | gcC | 1 | 9 | B.1.36.8 | 0.001 |
N | 35 | A35A | gcG | gcC | 2 | 8 | B.1.456 | 0.006536 |
N | 35 | A35A | gcG | gcC | 1 | 7 | A.1 | 0.000282 |
N | 35 | A35A | gcG | gcC | 2 | 7 | B.1.36.29 | 0.001035 |
N | 35 | A35A | gcG | gcC | 2 | 6 | A.2.5 | 0.000998 |
N | 35 | A35A | gcG | gcC | 1 | 6 | AY.16.1 | 0.00047 |
N | 35 | A35A | gcG | gcC | 6 | 6 | AY.39.1.1 | 0.004348 |
N | 35 | A35A | gcG | gcC | 4 | 6 | AY.66 | 0.004278 |
N | 35 | A35A | gcG | gcC | 2 | 6 | P.1.12 | 0.000968 |
N | 35 | A35A | gcG | gcC | 1 | 5 | AY.1 | 0.000396 |
N | 35 | A35A | gcG | gcC | 4 | 5 | AY.101 | 0.001962 |
N | 35 | A35A | gcG | gcC | 4 | 5 | AY.12 | 0.001264 |
N | 35 | A35A | gcG | gcC | 5 | 5 | B.1.160.26 | 0.012107 |
N | 35 | A35A | gcG | gcC | 2 | 5 | B.1.177.12 | 0.000303 |
N | 35 | A35A | gcG | gcC | 2 | 5 | D.2 | 0.00015 |
N | 35 | A35A | gcG | gcC | 4 | 4 | AY.79 | 0.004843 |
N | 35 | A35A | gcG | gcC | 2 | 4 | B.1.1.25 | 0.001137 |
N | 35 | A35A | gcG | gcC | 1 | 4 | B.1.1.433 | 0.001425 |
N | 35 | A35A | gcG | gcC | 1 | 4 | B.1.1.50 | 0.000679 |
N | 35 | A35A | gcG | gcC | 3 | 3 | AY.2 | 0.001068 |
N | 35 | A35A | gcG | gcC | 1 | 3 | B.1.1.263 | 0.001558 |
N | 35 | A35A | gcG | gcC | 2 | 3 | B.1.1.39 | 0.001019 |
N | 35 | A35A | gcG | gcC | 2 | 3 | B.6.6 | 0.001778 |
N | 35 | A35A | gcG | gcC | 1 | 3 | W.4 | 0.001351 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.1.135 | 0.004695 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.1.284 | 0.000107 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.1.368 | 0.003086 |
N | 35 | A35A | gcG | gcC | 2 | 2 | B.1.1.461 | 0.024096 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.1.464 | 0.001473 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.177.44 | 0.000519 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.236 | 0.002053 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.36.24 | 0.006173 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.1.416 | 0.001269 |
N | 35 | A35A | gcG | gcC | 1 | 2 | B.3.1 | 0.001658 |
N | 35 | A35A | gcG | gcC | 1 | 1 | AY.104 | 0.001984 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.10 | 0.001115 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.16 | 0.055556 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.161 | 0.003534 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.398 | 0.003226 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.413 | 0.006897 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.462 | 0.008621 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.1.83 | 0.00271 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.177.43 | 0.001477 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.177.86 | 0.000183 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.214 | 0.003663 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.36.10 | 0.004785 |
N | 35 | A35A | gcG | gcC | 1 | 1 | B.1.523 | 0.002451 |
N | 35 | A35A | gcG | gcC | 1 | 1 | M.3 | 0.076923 |
N | 35 | A35A | gcG | gcC | 1 | 1 | Q.4 | 0.000455 |
N | 35 | A35A | gcG | gcC | 1 | 1 | U.1 | 0.012821 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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