CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 348 | D348D | syn | gaT | gaC | 1580 | 1580 | 1 | 29315-29317 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 348 | D348D | gaT | gaC | 1580 | 1580 | All | 0.000302 |
N | 348 | D348D | gaT | gaC | 631 | 631 | B.1.1.432 | 0.798734 |
N | 348 | D348D | gaT | gaC | 128 | 128 | B.1.1.7 | 0.000115 |
N | 348 | D348D | gaT | gaC | 83 | 83 | AY.4 | 0.000129 |
N | 348 | D348D | gaT | gaC | 72 | 72 | AY.5 | 0.001487 |
N | 348 | D348D | gaT | gaC | 71 | 71 | B.1.617.2 | 0.000267 |
N | 348 | D348D | gaT | gaC | 69 | 69 | B.1 | 0.000632 |
N | 348 | D348D | gaT | gaC | 60 | 60 | P.1.14 | 0.002868 |
N | 348 | D348D | gaT | gaC | 59 | 59 | B.1.2 | 0.00052 |
N | 348 | D348D | gaT | gaC | 32 | 32 | AY.103 | 0.000199 |
N | 348 | D348D | gaT | gaC | 24 | 24 | B.1.22 | 0.031621 |
N | 348 | D348D | gaT | gaC | 20 | 20 | AY.44 | 0.000122 |
N | 348 | D348D | gaT | gaC | 19 | 19 | AY.71 | 0.009026 |
N | 348 | D348D | gaT | gaC | 17 | 17 | B.1.1 | 0.000308 |
N | 348 | D348D | gaT | gaC | 16 | 16 | AY.26 | 0.000453 |
N | 348 | D348D | gaT | gaC | 15 | 15 | B.1.1.37 | 0.002893 |
N | 348 | D348D | gaT | gaC | 14 | 14 | B.1.177.60 | 0.003058 |
N | 348 | D348D | gaT | gaC | 13 | 13 | P.1 | 0.000205 |
N | 348 | D348D | gaT | gaC | 12 | 12 | AY.43 | 0.000053 |
N | 348 | D348D | gaT | gaC | 12 | 12 | AY.99.2 | 0.001106 |
N | 348 | D348D | gaT | gaC | 12 | 12 | P.1.17 | 0.001941 |
N | 348 | D348D | gaT | gaC | 11 | 11 | B.1.177 | 0.000145 |
N | 348 | D348D | gaT | gaC | 8 | 8 | AY.102 | 0.000212 |
N | 348 | D348D | gaT | gaC | 8 | 8 | AY.25 | 0.000048 |
N | 348 | D348D | gaT | gaC | 7 | 7 | AY.3 | 0.00007 |
N | 348 | D348D | gaT | gaC | 7 | 7 | AY.33 | 0.000467 |
N | 348 | D348D | gaT | gaC | 7 | 7 | AY.4.2 | 0.000152 |
N | 348 | D348D | gaT | gaC | 7 | 7 | B.1.36 | 0.001021 |
N | 348 | D348D | gaT | gaC | 6 | 6 | AY.23 | 0.000418 |
N | 348 | D348D | gaT | gaC | 6 | 6 | B.1.111 | 0.007051 |
N | 348 | D348D | gaT | gaC | 5 | 5 | AY.120.1 | 0.001605 |
N | 348 | D348D | gaT | gaC | 5 | 5 | B | 0.000639 |
N | 348 | D348D | gaT | gaC | 5 | 5 | C.37 | 0.00058 |
N | 348 | D348D | gaT | gaC | 4 | 4 | AY.39.1 | 0.000158 |
N | 348 | D348D | gaT | gaC | 4 | 4 | B.1.1.158 | 0.04878 |
N | 348 | D348D | gaT | gaC | 4 | 4 | B.1.1.216 | 0.003562 |
N | 348 | D348D | gaT | gaC | 4 | 4 | P.1.4 | 0.003906 |
N | 348 | D348D | gaT | gaC | 3 | 3 | A | 0.001161 |
N | 348 | D348D | gaT | gaC | 3 | 3 | A.28 | 0.007937 |
N | 348 | D348D | gaT | gaC | 3 | 3 | AY.35 | 0.000699 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.1.159 | 0.014019 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.1.220 | 0.005576 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.1.222 | 0.000612 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.1.244 | 0.046154 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.375 | 0.002459 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.466.2 | 0.001174 |
N | 348 | D348D | gaT | gaC | 3 | 3 | B.1.596 | 0.000261 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.20 | 0.000078 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.3.1 | 0.000171 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.37 | 0.000632 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.47 | 0.000062 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.6 | 0.000082 |
N | 348 | D348D | gaT | gaC | 2 | 2 | AY.69 | 0.000373 |
N | 348 | D348D | gaT | gaC | 2 | 2 | B.1.206 | 0.001631 |
N | 348 | D348D | gaT | gaC | 2 | 2 | R.1 | 0.00018 |
N | 348 | D348D | gaT | gaC | 1 | 1 | 0.055556 | |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.116 | 0.000287 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.117 | 0.000085 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.120 | 0.000037 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.14 | 0.000088 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.16 | 0.00038 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.27 | 0.000065 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.30 | 0.000396 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.32 | 0.000532 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.34.1 | 0.00051 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.46.6 | 0.000072 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.54 | 0.000095 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.65 | 0.000533 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.79 | 0.001211 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.87 | 0.000833 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.90 | 0.000684 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.92 | 0.000287 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.98.1 | 0.000048 |
N | 348 | D348D | gaT | gaC | 1 | 1 | AY.99 | 0.001049 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.10 | 0.001115 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.186 | 0.003436 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.198 | 0.001468 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.214 | 0.000055 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.25 | 0.000569 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.279 | 0.001121 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.284 | 0.000107 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.306 | 0.000438 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.519 | 0.00004 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.1.89 | 0.006061 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.160 | 0.000031 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.177.50 | 0.004695 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.177.69 | 0.001484 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.179 | 0.003759 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.201 | 0.005682 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.258 | 0.000067 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.258.17 | 0.000104 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.351.3 | 0.000876 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.36.26 | 0.002857 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.36.27 | 0.000763 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.363 | 0.012987 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.427 | 0.00005 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.429 | 0.000024 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.525 | 0.000113 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.526 | 0.000024 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.564 | 0.000426 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.567 | 0.003333 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.571 | 0.009709 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.595 | 0.000261 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.609 | 0.000479 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.617.1 | 0.000129 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.1.78 | 0.008547 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.23 | 0.002924 |
N | 348 | D348D | gaT | gaC | 1 | 1 | B.29 | 0.003509 |
N | 348 | D348D | gaT | gaC | 1 | 1 | P.1.1 | 0.000318 |
N | 348 | D348D | gaT | gaC | 1 | 1 | P.1.15 | 0.000232 |
N | 348 | D348D | gaT | gaC | 1 | 1 | Q.1 | 0.000126 |
N | 348 | D348D | gaT | gaC | 1 | 1 | Q.8 | 0.000165 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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