CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 348 & Codon = Tat

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	348	D348Y		nonsyn	Gat	Tat	1571	1570	0.999363	29315-29317

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	348	D348Y	Gat	Tat	1570	1571	All	0.0003
N	348	D348Y	Gat	Tat	261	261	B.1.1.7	0.000234
N	348	D348Y	Gat	Tat	202	202	AY.4	0.000314
N	348	D348Y	Gat	Tat	113	113	AY.3	0.001124
N	348	D348Y	Gat	Tat	113	113	B.1.617.2	0.000425
N	348	D348Y	Gat	Tat	86	86	AY.7	0.016856
N	348	D348Y	Gat	Tat	43	43	AY.43	0.000191
N	348	D348Y	Gat	Tat	43	43	B.1.160	0.001341
N	348	D348Y	Gat	Tat	40	40	B.1.2	0.000352
N	348	D348Y	Gat	Tat	39	39	AY.44	0.000237
N	348	D348Y	Gat	Tat	38	38	AY.25	0.000229
N	348	D348Y	Gat	Tat	37	37	B.1	0.000339
N	348	D348Y	Gat	Tat	37	37	B.1.526	0.00087
N	348	D348Y	Gat	Tat	31	31	B.1.1.214	0.001719
N	348	D348Y	Gat	Tat	26	26	B.1.1	0.000472
N	348	D348Y	Gat	Tat	17	17	B.1.351	0.000505
N	348	D348Y	Gat	Tat	17	17	P.1	0.000268
N	348	D348Y	Gat	Tat	15	15	AY.39	0.000371
N	348	D348Y	Gat	Tat	14	14	AY.117	0.001183
N	348	D348Y	Gat	Tat	14	14	B.1.351.2	0.004236
N	348	D348Y	Gat	Tat	12	12	B.1.1.519	0.000477
N	348	D348Y	Gat	Tat	12	12	B.1.311	0.003295
N	348	D348Y	Gat	Tat	11	11	AY.33	0.000735
N	348	D348Y	Gat	Tat	10	10	AY.102	0.000265
N	348	D348Y	Gat	Tat	10	10	B.1.1.222	0.00204
N	348	D348Y	Gat	Tat	10	10	B.1.177	0.000132
N	348	D348Y	Gat	Tat	9	9	AY.47	0.00028
N	348	D348Y	Gat	Tat	9	9	B.1.177.12	0.001365
N	348	D348Y	Gat	Tat	8	8	AY.20	0.000311
N	348	D348Y	Gat	Tat	8	8	AY.42	0.000322
N	348	D348Y	Gat	Tat	7	7	AY.98.1	0.000339
N	348	D348Y	Gat	Tat	7	7	B.1.558	0.031963
N	348	D348Y	Gat	Tat	7	7	P.1.16	0.002619
N	348	D348Y	Gat	Tat	6	6	AY.5	0.000124
N	348	D348Y	Gat	Tat	6	6	AY.82	0.008141
N	348	D348Y	Gat	Tat	6	6	B.1.429	0.000141
N	348	D348Y	Gat	Tat	6	6	B.1.637	0.000438
N	348	D348Y	Gat	Tat	5	5	AY.14	0.00044
N	348	D348Y	Gat	Tat	5	5	AY.26	0.000142
N	348	D348Y	Gat	Tat	5	5	B.1.1.67	0.022831
N	348	D348Y	Gat	Tat	5	5	B.1.221	0.000355
N	348	D348Y	Gat	Tat	5	5	B.1.617.1	0.000645
N	348	D348Y	Gat	Tat	5	5	B.1.621	0.000443
N	348	D348Y	Gat	Tat	4	4	AY.119	0.000141
N	348	D348Y	Gat	Tat	4	4	AY.12	0.001264
N	348	D348Y	Gat	Tat	4	4	AY.121	0.000541
N	348	D348Y	Gat	Tat	4	4	AY.29	0.000063
N	348	D348Y	Gat	Tat	4	4	AY.32	0.00213
N	348	D348Y	Gat	Tat	4	4	B.1.1.301	0.004717
N	348	D348Y	Gat	Tat	4	4	B.1.1.318	0.001207
N	348	D348Y	Gat	Tat	4	4	B.1.110.3	0.002874
N	348	D348Y	Gat	Tat	4	4	B.1.128	0.002541
N	348	D348Y	Gat	Tat	4	4	B.1.177.21	0.000306
N	348	D348Y	Gat	Tat	4	4	B.1.36	0.000584
N	348	D348Y	Gat	Tat	4	4	B.1.596	0.000349
N	348	D348Y	Gat	Tat	4	4	P.1.1	0.001271
N	348	D348Y	Gat	Tat	3	3	AY.3.1	0.000256
N	348	D348Y	Gat	Tat	3	3	AY.34	0.000291
N	348	D348Y	Gat	Tat	3	3	AY.4.5	0.000322
N	348	D348Y	Gat	Tat	3	3	AY.9.1	0.000251
N	348	D348Y	Gat	Tat	3	3	B.1.1.25	0.001706
N	348	D348Y	Gat	Tat	3	3	B.1.1.70	0.001023
N	348	D348Y	Gat	Tat	3	3	B.1.199	0.012397
N	348	D348Y	Gat	Tat	3	3	B.1.243	0.000209
N	348	D348Y	Gat	Tat	3	3	B.1.258	0.0002
N	348	D348Y	Gat	Tat	3	3	B.1.427	0.000151
N	348	D348Y	Gat	Tat	3	3	B.1.561	0.001191
N	348	D348Y	Gat	Tat	3	3	B.27	0.046154
N	348	D348Y	Gat	Tat	3	3	P.1.14	0.000143
N	348	D348Y	Gat	Tat	2	2	AY.10	0.00106
N	348	D348Y	Gat	Tat	2	2	AY.100	0.000092
N	348	D348Y	Gat	Tat	2	2	AY.103	0.000012
N	348	D348Y	Gat	Tat	2	2	AY.120	0.000074
N	348	D348Y	Gat	Tat	2	2	AY.13	0.000322
N	348	D348Y	Gat	Tat	2	2	AY.23	0.000139
N	348	D348Y	Gat	Tat	2	2	AY.27	0.000129
N	348	D348Y	Gat	Tat	2	2	AY.28	0.003781
N	348	D348Y	Gat	Tat	2	2	AY.4.2	0.000043
N	348	D348Y	Gat	Tat	2	2	AY.45	0.000243
N	348	D348Y	Gat	Tat	2	2	AY.46	0.000208
N	348	D348Y	Gat	Tat	2	2	AY.48	0.00093
N	348	D348Y	Gat	Tat	2	2	AY.53	0.000575
N	348	D348Y	Gat	Tat	2	2	AY.62	0.000871
N	348	D348Y	Gat	Tat	2	2	AY.74	0.000231
N	348	D348Y	Gat	Tat	2	2	AY.9	0.000135
N	348	D348Y	Gat	Tat	2	2	B.1.1.117	0.019417
N	348	D348Y	Gat	Tat	2	2	B.1.1.207	0.002364
N	348	D348Y	Gat	Tat	2	2	B.1.1.263	0.003115
N	348	D348Y	Gat	Tat	2	2	B.1.1.354	0.008772
N	348	D348Y	Gat	Tat	2	2	B.1.1.39	0.001019
N	348	D348Y	Gat	Tat	2	2	B.1.1.4	0.005952
N	348	D348Y	Gat	Tat	2	2	B.1.305	0.004301
N	348	D348Y	Gat	Tat	2	2	C.37	0.000232
N	348	D348Y	Gat	Tat	1	1		0.055556
N	348	D348Y	Gat	Tat	1	1	A	0.000387
N	348	D348Y	Gat	Tat	1	1	A.3	0.002096
N	348	D348Y	Gat	Tat	1	1	AD.2	0.000219
N	348	D348Y	Gat	Tat	1	1	AY.116	0.000287
N	348	D348Y	Gat	Tat	1	1	AY.118	0.000063
N	348	D348Y	Gat	Tat	1	1	AY.16	0.00038
N	348	D348Y	Gat	Tat	1	1	AY.19	0.00114
N	348	D348Y	Gat	Tat	1	1	AY.30	0.000396
N	348	D348Y	Gat	Tat	1	1	AY.37	0.000316
N	348	D348Y	Gat	Tat	1	1	AY.46.4	0.000165
N	348	D348Y	Gat	Tat	1	1	AY.46.6	0.000072
N	348	D348Y	Gat	Tat	1	1	AY.55	0.000917
N	348	D348Y	Gat	Tat	1	1	AY.6	0.000041
N	348	D348Y	Gat	Tat	1	1	AY.61	0.000105
N	348	D348Y	Gat	Tat	1	1	AY.68	0.000274
N	348	D348Y	Gat	Tat	1	1	AY.69	0.000187
N	348	D348Y	Gat	Tat	1	1	AY.75.1	0.00018
N	348	D348Y	Gat	Tat	1	1	AY.83	0.001724
N	348	D348Y	Gat	Tat	1	1	AY.9.2	0.000037
N	348	D348Y	Gat	Tat	1	1	AY.92	0.000287
N	348	D348Y	Gat	Tat	1	1	AY.95	0.000761
N	348	D348Y	Gat	Tat	1	1	B	0.000128
N	348	D348Y	Gat	Tat	1	1	B.1.1.141	0.002012
N	348	D348Y	Gat	Tat	1	1	B.1.1.157	0.000913
N	348	D348Y	Gat	Tat	1	1	B.1.1.187	0.00885
N	348	D348Y	Gat	Tat	1	1	B.1.1.216	0.00089
N	348	D348Y	Gat	Tat	1	1	B.1.1.316	0.000925
N	348	D348Y	Gat	Tat	1	1	B.1.1.348	0.000796
N	348	D348Y	Gat	Tat	1	1	B.1.1.37	0.000193
N	348	D348Y	Gat	Tat	1	1	B.1.1.371	0.010417
N	348	D348Y	Gat	Tat	1	1	B.1.1.419	0.007407
N	348	D348Y	Gat	Tat	1	1	B.1.1.50	0.000679
N	348	D348Y	Gat	Tat	1	1	B.1.1.63	0.000386
N	348	D348Y	Gat	Tat	1	1	B.1.1.89	0.006061
N	348	D348Y	Gat	Tat	1	1	B.1.160.14	0.002119
N	348	D348Y	Gat	Tat	1	1	B.1.177.73	0.000566
N	348	D348Y	Gat	Tat	1	1	B.1.177.82	0.000477
N	348	D348Y	Gat	Tat	1	1	B.1.177.84	0.006667
N	348	D348Y	Gat	Tat	1	1	B.1.177.86	0.000183
N	348	D348Y	Gat	Tat	1	1	B.1.215	0.009615
N	348	D348Y	Gat	Tat	1	1	B.1.235	0.002519
N	348	D348Y	Gat	Tat	1	1	B.1.240	0.000216
N	348	D348Y	Gat	Tat	1	1	B.1.241	0.000812
N	348	D348Y	Gat	Tat	1	1	B.1.258.14	0.00098
N	348	D348Y	Gat	Tat	1	1	B.1.258.4	0.003448
N	348	D348Y	Gat	Tat	1	1	B.1.320	0.001245
N	348	D348Y	Gat	Tat	1	1	B.1.36.29	0.000517
N	348	D348Y	Gat	Tat	1	1	B.1.36.8	0.001
N	348	D348Y	Gat	Tat	1	1	B.1.367	0.000792
N	348	D348Y	Gat	Tat	1	1	B.1.391	0.001127
N	348	D348Y	Gat	Tat	1	1	B.1.400	0.000429
N	348	D348Y	Gat	Tat	1	1	B.1.415.1	0.007576
N	348	D348Y	Gat	Tat	1	1	B.1.428	0.00102
N	348	D348Y	Gat	Tat	1	1	B.1.497	0.000315
N	348	D348Y	Gat	Tat	1	1	B.1.517	0.000427
N	348	D348Y	Gat	Tat	1	1	B.1.523	0.002451
N	348	D348Y	Gat	Tat	1	1	B.1.541	0.004425
N	348	D348Y	Gat	Tat	1	1	B.1.551	0.00129
N	348	D348Y	Gat	Tat	1	1	B.1.567	0.003333
N	348	D348Y	Gat	Tat	1	1	B.1.577	0.000687
N	348	D348Y	Gat	Tat	1	1	B.1.582	0.000491
N	348	D348Y	Gat	Tat	1	1	B.1.587	0.001898
N	348	D348Y	Gat	Tat	1	1	B.1.595	0.000261
N	348	D348Y	Gat	Tat	1	1	B.1.628	0.000352
N	348	D348Y	Gat	Tat	1	1	B.1.635	0.017544
N	348	D348Y	Gat	Tat	1	1	B.15	0.017544
N	348	D348Y	Gat	Tat	1	1	B.40	0.000364
N	348	D348Y	Gat	Tat	1	1	B.45	0.003831
N	348	D348Y	Gat	Tat	1	1	P.1.7	0.000319
N	348	D348Y	Gat	Tat	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.