CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 319 | R319R | syn | cgC | cgT | 1634 | 1619 | 0.99082 | 29228-29230 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 319 | R319R | cgC | cgT | 1619 | 1634 | All | 0.00031 |
N | 319 | R319R | cgC | cgT | 791 | 792 | AY.25 | 0.004758 |
N | 319 | R319R | cgC | cgT | 146 | 146 | AY.4 | 0.000227 |
N | 319 | R319R | cgC | cgT | 125 | 126 | B.1.1.7 | 0.000112 |
N | 319 | R319R | cgC | cgT | 85 | 85 | AY.44 | 0.000517 |
N | 319 | R319R | cgC | cgT | 45 | 45 | B.1.1.500 | 0.9 |
N | 319 | R319R | cgC | cgT | 37 | 37 | B.1.258 | 0.002462 |
N | 319 | R319R | cgC | cgT | 33 | 33 | B.1.177.60 | 0.007208 |
N | 319 | R319R | cgC | cgT | 33 | 33 | B.1.617.2 | 0.000124 |
N | 319 | R319R | cgC | cgT | 18 | 18 | AY.5 | 0.000372 |
N | 319 | R319R | cgC | cgT | 14 | 14 | B.1.177 | 0.000184 |
N | 319 | R319R | cgC | cgT | 14 | 14 | B.1.177.23 | 0.045307 |
N | 319 | R319R | cgC | cgT | 12 | 13 | AY.103 | 0.000075 |
N | 319 | R319R | cgC | cgT | 12 | 12 | B.1.429 | 0.000282 |
N | 319 | R319R | cgC | cgT | 11 | 11 | B.1 | 0.000101 |
N | 319 | R319R | cgC | cgT | 9 | 10 | AY.3 | 0.00009 |
N | 319 | R319R | cgC | cgT | 10 | 10 | AY.39 | 0.000247 |
N | 319 | R319R | cgC | cgT | 9 | 9 | AY.121 | 0.001218 |
N | 319 | R319R | cgC | cgT | 8 | 9 | AY.43 | 0.000035 |
N | 319 | R319R | cgC | cgT | 9 | 9 | B.1.2 | 0.000079 |
N | 319 | R319R | cgC | cgT | 7 | 8 | AY.29 | 0.00011 |
N | 319 | R319R | cgC | cgT | 8 | 8 | AY.75 | 0.000448 |
N | 319 | R319R | cgC | cgT | 8 | 8 | AY.94 | 0.003541 |
N | 319 | R319R | cgC | cgT | 8 | 8 | B.1.526 | 0.000188 |
N | 319 | R319R | cgC | cgT | 7 | 7 | B.1.595 | 0.001827 |
N | 319 | R319R | cgC | cgT | 7 | 7 | B.1.596 | 0.00061 |
N | 319 | R319R | cgC | cgT | 6 | 6 | AY.117 | 0.000507 |
N | 319 | R319R | cgC | cgT | 5 | 6 | AY.4.2 | 0.000108 |
N | 319 | R319R | cgC | cgT | 6 | 6 | B.1.1 | 0.000109 |
N | 319 | R319R | cgC | cgT | 6 | 6 | P.1 | 0.000095 |
N | 319 | R319R | cgC | cgT | 4 | 4 | AY.95 | 0.003044 |
N | 319 | R319R | cgC | cgT | 4 | 4 | B.1.160 | 0.000125 |
N | 319 | R319R | cgC | cgT | 4 | 4 | B.1.177.12 | 0.000607 |
N | 319 | R319R | cgC | cgT | 4 | 4 | B.1.525 | 0.000453 |
N | 319 | R319R | cgC | cgT | 4 | 4 | B.1.590 | 0.018182 |
N | 319 | R319R | cgC | cgT | 3 | 3 | 0.166667 | |
N | 319 | R319R | cgC | cgT | 3 | 3 | AU.3 | 0.006329 |
N | 319 | R319R | cgC | cgT | 3 | 3 | AY.100 | 0.000138 |
N | 319 | R319R | cgC | cgT | 3 | 3 | AY.20 | 0.000117 |
N | 319 | R319R | cgC | cgT | 3 | 3 | AY.36 | 0.000445 |
N | 319 | R319R | cgC | cgT | 3 | 3 | AY.7 | 0.000588 |
N | 319 | R319R | cgC | cgT | 3 | 3 | B.1.1.519 | 0.000119 |
N | 319 | R319R | cgC | cgT | 3 | 3 | B.1.177.86 | 0.00055 |
N | 319 | R319R | cgC | cgT | 2 | 3 | B.1.351 | 0.000059 |
N | 319 | R319R | cgC | cgT | 3 | 3 | D.2 | 0.000225 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.102 | 0.000053 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.109 | 0.001479 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.110 | 0.000225 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.14 | 0.000176 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.23 | 0.000139 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.26 | 0.000057 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.39.1 | 0.000079 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.42 | 0.00008 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.45 | 0.000243 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.46 | 0.000208 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.54 | 0.000191 |
N | 319 | R319R | cgC | cgT | 2 | 2 | AY.58 | 0.001815 |
N | 319 | R319R | cgC | cgT | 2 | 2 | B.1.1.28 | 0.000622 |
N | 319 | R319R | cgC | cgT | 2 | 2 | B.1.1.39 | 0.001019 |
N | 319 | R319R | cgC | cgT | 2 | 2 | B.1.575 | 0.000607 |
N | 319 | R319R | cgC | cgT | 2 | 2 | B.1.637 | 0.000146 |
N | 319 | R319R | cgC | cgT | 2 | 2 | C.38 | 0.016129 |
N | 319 | R319R | cgC | cgT | 2 | 2 | P.1.14 | 0.000096 |
N | 319 | R319R | cgC | cgT | 1 | 1 | A | 0.000387 |
N | 319 | R319R | cgC | cgT | 1 | 1 | A.3 | 0.002096 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AD.2 | 0.000219 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.104 | 0.001984 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.113 | 0.000142 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.12 | 0.000316 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.120.2.1 | 0.000498 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.24 | 0.000431 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.29.1 | 0.000221 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.3.1 | 0.000085 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.33 | 0.000067 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.34 | 0.000097 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.4.2.1 | 0.000149 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.5.4 | 0.000277 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.61 | 0.000105 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.68 | 0.000274 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.71 | 0.000475 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.89 | 0.004902 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.90 | 0.000684 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.98 | 0.000079 |
N | 319 | R319R | cgC | cgT | 1 | 1 | AY.98.1 | 0.000048 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B | 0.000128 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.1.117 | 0.009709 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.1.306 | 0.000438 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.1.318 | 0.000302 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.1.41 | 0.006329 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.1.50 | 0.000679 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.177.21 | 0.000076 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.177.40 | 0.005155 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.214.2 | 0.0006 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.240 | 0.000216 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.243 | 0.00007 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.258.2 | 0.004505 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.289 | 0.00266 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.36.16 | 0.001425 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.380 | 0.006623 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.398 | 0.002976 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.466.2 | 0.000391 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.623 | 0.000536 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.1.8 | 0.001972 |
N | 319 | R319R | cgC | cgT | 1 | 1 | B.5 | 0.038462 |
N | 319 | R319R | cgC | cgT | 1 | 1 | N.4 | 0.004255 |
N | 319 | R319R | cgC | cgT | 1 | 1 | P.1.7 | 0.000319 |
N | 319 | R319R | cgC | cgT | 1 | 1 | Q.8 | 0.000165 |
N | 319 | R319R | cgC | cgT | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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