CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 318 | S318S | syn | tcG | tcA | 15396 | 1691 | 0.109834 | 29225-29227 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 318 | S318S | tcG | tcA | 1691 | 15396 | All | 0.000323 |
N | 318 | S318S | tcG | tcA | 2 | 1998 | B.1.1.519 | 0.000079 |
N | 318 | S318S | tcG | tcA | 276 | 1825 | B.1.1.7 | 0.000247 |
N | 318 | S318S | tcG | tcA | 21 | 611 | B.1.617.2 | 0.000079 |
N | 318 | S318S | tcG | tcA | 148 | 557 | AY.4 | 0.00023 |
N | 318 | S318S | tcG | tcA | 26 | 520 | AY.43 | 0.000115 |
N | 318 | S318S | tcG | tcA | 448 | 449 | AY.78 | 0.690293 |
N | 318 | S318S | tcG | tcA | 78 | 370 | AY.103 | 0.000484 |
N | 318 | S318S | tcG | tcA | 40 | 270 | AY.44 | 0.000243 |
N | 318 | S318S | tcG | tcA | 37 | 172 | B.1 | 0.000339 |
N | 318 | S318S | tcG | tcA | 9 | 148 | AY.102 | 0.000239 |
N | 318 | S318S | tcG | tcA | 16 | 142 | AY.25 | 0.000096 |
N | 318 | S318S | tcG | tcA | 32 | 130 | B.1.2 | 0.000282 |
N | 318 | S318S | tcG | tcA | 1 | 126 | AY.26 | 0.000028 |
N | 318 | S318S | tcG | tcA | 19 | 121 | B.1.243 | 0.001322 |
N | 318 | S318S | tcG | tcA | 2 | 98 | B.1.596 | 0.000174 |
N | 318 | S318S | tcG | tcA | 2 | 90 | B.1.160 | 0.000062 |
N | 318 | S318S | tcG | tcA | 14 | 89 | B.1.1 | 0.000254 |
N | 318 | S318S | tcG | tcA | 20 | 71 | AY.3 | 0.000199 |
N | 318 | S318S | tcG | tcA | 14 | 70 | P.1 | 0.000221 |
N | 318 | S318S | tcG | tcA | 46 | 62 | B.1.429 | 0.001082 |
N | 318 | S318S | tcG | tcA | 1 | 56 | AY.4.2 | 0.000022 |
N | 318 | S318S | tcG | tcA | 3 | 56 | AY.47 | 0.000093 |
N | 318 | S318S | tcG | tcA | 6 | 48 | AY.39 | 0.000148 |
N | 318 | S318S | tcG | tcA | 24 | 48 | AY.42 | 0.000966 |
N | 318 | S318S | tcG | tcA | 26 | 43 | AY.29 | 0.00041 |
N | 318 | S318S | tcG | tcA | 9 | 42 | B.1.177 | 0.000119 |
N | 318 | S318S | tcG | tcA | 19 | 39 | AY.20 | 0.000738 |
N | 318 | S318S | tcG | tcA | 38 | 39 | B.1.1.305 | 0.146718 |
N | 318 | S318S | tcG | tcA | 17 | 38 | AY.120 | 0.000632 |
N | 318 | S318S | tcG | tcA | 35 | 37 | AY.91 | 0.025566 |
N | 318 | S318S | tcG | tcA | 9 | 28 | AY.23 | 0.000628 |
N | 318 | S318S | tcG | tcA | 2 | 28 | AY.5 | 0.000041 |
N | 318 | S318S | tcG | tcA | 16 | 27 | B.1.221 | 0.001137 |
N | 318 | S318S | tcG | tcA | 12 | 26 | AY.34 | 0.001164 |
N | 318 | S318S | tcG | tcA | 23 | 26 | AY.36 | 0.003409 |
N | 318 | S318S | tcG | tcA | 19 | 25 | AY.14 | 0.001672 |
N | 318 | S318S | tcG | tcA | 6 | 23 | AY.119 | 0.000212 |
N | 318 | S318S | tcG | tcA | 1 | 23 | AY.33 | 0.000067 |
N | 318 | S318S | tcG | tcA | 11 | 21 | B.1.526 | 0.000259 |
N | 318 | S318S | tcG | tcA | 2 | 19 | B.1.36.29 | 0.001035 |
N | 318 | S318S | tcG | tcA | 1 | 15 | B.1.36 | 0.000146 |
N | 318 | S318S | tcG | tcA | 12 | 15 | R.1 | 0.00108 |
N | 318 | S318S | tcG | tcA | 6 | 14 | P.1.14 | 0.000287 |
N | 318 | S318S | tcG | tcA | 1 | 13 | AY.75 | 0.000056 |
N | 318 | S318S | tcG | tcA | 1 | 12 | AY.98.1 | 0.000048 |
N | 318 | S318S | tcG | tcA | 11 | 11 | AY.57 | 0.007218 |
N | 318 | S318S | tcG | tcA | 2 | 11 | AY.99.2 | 0.000184 |
N | 318 | S318S | tcG | tcA | 8 | 11 | B.1.1.318 | 0.002414 |
N | 318 | S318S | tcG | tcA | 2 | 11 | B.1.351 | 0.000059 |
N | 318 | S318S | tcG | tcA | 10 | 11 | B.1.561 | 0.00397 |
N | 318 | S318S | tcG | tcA | 2 | 10 | AY.117 | 0.000169 |
N | 318 | S318S | tcG | tcA | 4 | 10 | AY.118 | 0.000251 |
N | 318 | S318S | tcG | tcA | 1 | 10 | AY.9.1 | 0.000084 |
N | 318 | S318S | tcG | tcA | 2 | 9 | AY.100 | 0.000092 |
N | 318 | S318S | tcG | tcA | 8 | 9 | AY.4.5 | 0.00086 |
N | 318 | S318S | tcG | tcA | 5 | 8 | AY.121 | 0.000677 |
N | 318 | S318S | tcG | tcA | 1 | 8 | AY.27 | 0.000065 |
N | 318 | S318S | tcG | tcA | 1 | 8 | B.1.258 | 0.000067 |
N | 318 | S318S | tcG | tcA | 1 | 8 | B.1.617.1 | 0.000129 |
N | 318 | S318S | tcG | tcA | 1 | 7 | AY.12 | 0.000316 |
N | 318 | S318S | tcG | tcA | 6 | 7 | AY.16 | 0.002278 |
N | 318 | S318S | tcG | tcA | 4 | 7 | B.1.525 | 0.000453 |
N | 318 | S318S | tcG | tcA | 1 | 7 | B.1.575 | 0.000303 |
N | 318 | S318S | tcG | tcA | 2 | 7 | C.37 | 0.000232 |
N | 318 | S318S | tcG | tcA | 2 | 7 | P.2 | 0.000373 |
N | 318 | S318S | tcG | tcA | 3 | 6 | AY.69 | 0.00056 |
N | 318 | S318S | tcG | tcA | 1 | 5 | AY.92 | 0.000287 |
N | 318 | S318S | tcG | tcA | 1 | 4 | AY.105 | 0.000643 |
N | 318 | S318S | tcG | tcA | 1 | 4 | AY.75.1 | 0.00018 |
N | 318 | S318S | tcG | tcA | 1 | 4 | AY.85 | 0.000427 |
N | 318 | S318S | tcG | tcA | 4 | 4 | B.1.36.8 | 0.004 |
N | 318 | S318S | tcG | tcA | 2 | 4 | B.1.369 | 0.00057 |
N | 318 | S318S | tcG | tcA | 3 | 3 | AY.1 | 0.001187 |
N | 318 | S318S | tcG | tcA | 1 | 3 | AY.110 | 0.000113 |
N | 318 | S318S | tcG | tcA | 1 | 3 | AY.116 | 0.000287 |
N | 318 | S318S | tcG | tcA | 1 | 3 | AY.4.2.1 | 0.000149 |
N | 318 | S318S | tcG | tcA | 1 | 3 | AY.46.2 | 0.000635 |
N | 318 | S318S | tcG | tcA | 1 | 3 | AY.5.4 | 0.000277 |
N | 318 | S318S | tcG | tcA | 2 | 3 | AY.87 | 0.001665 |
N | 318 | S318S | tcG | tcA | 1 | 3 | B.1.234 | 0.000132 |
N | 318 | S318S | tcG | tcA | 1 | 3 | B.1.438.1 | 0.000107 |
N | 318 | S318S | tcG | tcA | 1 | 3 | B.1.466.2 | 0.000391 |
N | 318 | S318S | tcG | tcA | 1 | 3 | B.1.619.1 | 0.000641 |
N | 318 | S318S | tcG | tcA | 2 | 2 | A.2 | 0.001324 |
N | 318 | S318S | tcG | tcA | 1 | 2 | AY.114 | 0.000231 |
N | 318 | S318S | tcG | tcA | 1 | 2 | AY.24 | 0.000431 |
N | 318 | S318S | tcG | tcA | 1 | 2 | AY.55 | 0.000917 |
N | 318 | S318S | tcG | tcA | 1 | 2 | AY.64 | 0.000595 |
N | 318 | S318S | tcG | tcA | 1 | 2 | B.1.1.284 | 0.000107 |
N | 318 | S318S | tcG | tcA | 2 | 2 | B.1.1.70 | 0.000682 |
N | 318 | S318S | tcG | tcA | 2 | 2 | B.1.177.4 | 0.000422 |
N | 318 | S318S | tcG | tcA | 1 | 2 | B.1.311 | 0.000275 |
N | 318 | S318S | tcG | tcA | 1 | 2 | B.1.366 | 0.004878 |
N | 318 | S318S | tcG | tcA | 1 | 2 | B.1.400 | 0.000429 |
N | 318 | S318S | tcG | tcA | 2 | 2 | B.1.416 | 0.002538 |
N | 318 | S318S | tcG | tcA | 1 | 1 | A.1 | 0.000282 |
N | 318 | S318S | tcG | tcA | 1 | 1 | A.12 | 0.166667 |
N | 318 | S318S | tcG | tcA | 1 | 1 | AY.86 | 0.00083 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.200 | 0.007463 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.232 | 0.001815 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.279 | 0.001121 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.351 | 0.002793 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.523 | 0.001563 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.1.54 | 0.003021 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.104 | 0.00369 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.177.11 | 0.001698 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.177.12 | 0.000152 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.177.16 | 0.000664 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.177.60 | 0.000218 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.201 | 0.005682 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.396 | 0.000706 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.421 | 0.007463 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.527 | 0.003704 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.538 | 0.008065 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.556 | 0.007519 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.564 | 0.000426 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.609 | 0.000479 |
N | 318 | S318S | tcG | tcA | 1 | 1 | B.1.69 | 0.035714 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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