CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 3 | D3L | nonsyn | GAT | CTA | 1132443 | 1129900 | 0.997754 | 28280-28282 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 3 | D3L | GAT | CTA | 1129900 | 1132443 | All | 0.216107 |
N | 3 | D3L | GAT | CTA | 1099460 | 1100535 | B.1.1.7 | 0.984262 |
N | 3 | D3L | GAT | CTA | 7763 | 7784 | Q.1 | 0.980672 |
N | 3 | D3L | GAT | CTA | 6707 | 6708 | Q.3 | 0.972734 |
N | 3 | D3L | GAT | CTA | 6024 | 6027 | Q.8 | 0.993404 |
N | 3 | D3L | GAT | CTA | 2773 | 3380 | B.1.1 | 0.050305 |
N | 3 | D3L | GAT | CTA | 1965 | 1966 | Q.4 | 0.893588 |
N | 3 | D3L | GAT | CTA | 1623 | 1624 | Q.2 | 0.995706 |
N | 3 | D3L | GAT | CTA | 1023 | 1489 | B.1 | 0.00937 |
N | 3 | D3L | GAT | CTA | 891 | 891 | Q.7 | 0.99 |
N | 3 | D3L | GAT | CTA | 144 | 202 | B.1.177.73 | 0.08154 |
N | 3 | D3L | GAT | CTA | 140 | 140 | Q.6 | 0.927152 |
N | 3 | D3L | GAT | CTA | 138 | 138 | B.1.214.2 | 0.082734 |
N | 3 | D3L | GAT | CTA | 36 | 71 | B.1.1.409 | 0.101983 |
N | 3 | D3L | GAT | CTA | 58 | 64 | B | 0.007413 |
N | 3 | D3L | GAT | CTA | 48 | 62 | B.1.375 | 0.039344 |
N | 3 | D3L | GAT | CTA | 46 | 60 | B.1.177 | 0.000606 |
N | 3 | D3L | GAT | CTA | 39 | 59 | B.1.221 | 0.00277 |
N | 3 | D3L | GAT | CTA | 59 | 59 | Q.5 | 1 |
N | 3 | D3L | GAT | CTA | 37 | 52 | B.1.2 | 0.000326 |
N | 3 | D3L | GAT | CTA | 44 | 47 | B.1.258.17 | 0.004575 |
N | 3 | D3L | GAT | CTA | 38 | 47 | B.1.576 | 0.034451 |
N | 3 | D3L | GAT | CTA | 44 | 47 | P.1 | 0.000693 |
N | 3 | D3L | GAT | CTA | 45 | 45 | XA | 1 |
N | 3 | D3L | GAT | CTA | 36 | 43 | B.1.526 | 0.000846 |
N | 3 | D3L | GAT | CTA | 38 | 39 | P.1.1 | 0.012071 |
N | 3 | D3L | GAT | CTA | 35 | 38 | AY.44 | 0.000213 |
N | 3 | D3L | GAT | CTA | 27 | 38 | B.1.177.7 | 0.004451 |
N | 3 | D3L | GAT | CTA | 25 | 38 | B.1.596 | 0.002178 |
N | 3 | D3L | GAT | CTA | 14 | 27 | B.1.1.507 | 0.121739 |
N | 3 | D3L | GAT | CTA | 21 | 26 | B.1.617.2 | 0.000079 |
N | 3 | D3L | GAT | CTA | 22 | 22 | B.1.214.3 | 0.157143 |
N | 3 | D3L | GAT | CTA | 11 | 21 | B.1.1.161 | 0.038869 |
N | 3 | D3L | GAT | CTA | 18 | 21 | B.1.1.519 | 0.000715 |
N | 3 | D3L | GAT | CTA | 19 | 21 | B.1.351 | 0.000565 |
N | 3 | D3L | GAT | CTA | 16 | 20 | B.1.160 | 0.000499 |
N | 3 | D3L | GAT | CTA | 12 | 19 | AY.43 | 0.000053 |
N | 3 | D3L | GAT | CTA | 11 | 16 | 0.611111 | |
N | 3 | D3L | GAT | CTA | 16 | 16 | AY.26 | 0.000453 |
N | 3 | D3L | GAT | CTA | 13 | 15 | B.1.1.220 | 0.024164 |
N | 3 | D3L | GAT | CTA | 11 | 12 | AY.29 | 0.000174 |
N | 3 | D3L | GAT | CTA | 12 | 12 | P.1.16 | 0.004489 |
N | 3 | D3L | GAT | CTA | 11 | 11 | B.1.1.312 | 0.021033 |
N | 3 | D3L | GAT | CTA | 9 | 11 | B.1.429 | 0.000212 |
N | 3 | D3L | GAT | CTA | 11 | 11 | B.1.525 | 0.001245 |
N | 3 | D3L | GAT | CTA | 7 | 11 | B.1.623 | 0.003755 |
N | 3 | D3L | GAT | CTA | 10 | 10 | B.1.1.39 | 0.005097 |
N | 3 | D3L | GAT | CTA | 7 | 10 | B.1.139 | 0.005132 |
N | 3 | D3L | GAT | CTA | 8 | 10 | B.1.427 | 0.000404 |
N | 3 | D3L | GAT | CTA | 10 | 10 | B.1.609 | 0.004794 |
N | 3 | D3L | GAT | CTA | 6 | 9 | AY.4 | 0.000009 |
N | 3 | D3L | GAT | CTA | 7 | 9 | B.1.311 | 0.001922 |
N | 3 | D3L | GAT | CTA | 8 | 9 | B.1.621 | 0.000708 |
N | 3 | D3L | GAT | CTA | 5 | 8 | A.2.5 | 0.002495 |
N | 3 | D3L | GAT | CTA | 4 | 8 | AY.42 | 0.000161 |
N | 3 | D3L | GAT | CTA | 7 | 8 | B.1.1.70 | 0.002387 |
N | 3 | D3L | GAT | CTA | 8 | 8 | B.1.258 | 0.000532 |
N | 3 | D3L | GAT | CTA | 4 | 7 | A | 0.001548 |
N | 3 | D3L | GAT | CTA | 6 | 7 | AY.25 | 0.000036 |
N | 3 | D3L | GAT | CTA | 6 | 7 | B.1.1.28 | 0.001867 |
N | 3 | D3L | GAT | CTA | 4 | 7 | B.1.617.1 | 0.000516 |
N | 3 | D3L | GAT | CTA | 4 | 7 | B.1.637 | 0.000292 |
N | 3 | D3L | GAT | CTA | 6 | 6 | AY.30 | 0.002374 |
N | 3 | D3L | GAT | CTA | 3 | 6 | AY.92 | 0.000862 |
N | 3 | D3L | GAT | CTA | 5 | 6 | B.1.1.10 | 0.005574 |
N | 3 | D3L | GAT | CTA | 3 | 6 | B.1.1.370 | 0.037975 |
N | 3 | D3L | GAT | CTA | 6 | 6 | B.1.1.528 | 0.028846 |
N | 3 | D3L | GAT | CTA | 6 | 6 | B.1.336 | 0.014634 |
N | 3 | D3L | GAT | CTA | 3 | 6 | B.1.369 | 0.000856 |
N | 3 | D3L | GAT | CTA | 6 | 6 | B.1.411 | 0.022222 |
N | 3 | D3L | GAT | CTA | 4 | 6 | B.1.595 | 0.001044 |
N | 3 | D3L | GAT | CTA | 6 | 6 | B.1.625 | 0.014118 |
N | 3 | D3L | GAT | CTA | 4 | 6 | P.1.12 | 0.001936 |
N | 3 | D3L | GAT | CTA | 6 | 6 | R.1 | 0.00054 |
N | 3 | D3L | GAT | CTA | 5 | 5 | AY.102 | 0.000133 |
N | 3 | D3L | GAT | CTA | 3 | 5 | AY.52 | 0.002443 |
N | 3 | D3L | GAT | CTA | 5 | 5 | B.1.1.294 | 0.006329 |
N | 3 | D3L | GAT | CTA | 3 | 5 | B.1.580 | 0.012195 |
N | 3 | D3L | GAT | CTA | 4 | 5 | B.1.628 | 0.001409 |
N | 3 | D3L | GAT | CTA | 3 | 5 | C.36.3 | 0.001702 |
N | 3 | D3L | GAT | CTA | 5 | 5 | P.1.17 | 0.000809 |
N | 3 | D3L | GAT | CTA | 3 | 4 | AY.75.1 | 0.000541 |
N | 3 | D3L | GAT | CTA | 3 | 4 | B.1.149 | 0.010274 |
N | 3 | D3L | GAT | CTA | 4 | 4 | B.1.157 | 0.01194 |
N | 3 | D3L | GAT | CTA | 2 | 4 | B.1.177.86 | 0.000367 |
N | 3 | D3L | GAT | CTA | 4 | 4 | B.1.214 | 0.014652 |
N | 3 | D3L | GAT | CTA | 3 | 4 | B.1.234 | 0.000396 |
N | 3 | D3L | GAT | CTA | 3 | 4 | B.1.243 | 0.000209 |
N | 3 | D3L | GAT | CTA | 4 | 4 | B.1.258.14 | 0.003922 |
N | 3 | D3L | GAT | CTA | 2 | 4 | B.1.397 | 0.009709 |
N | 3 | D3L | GAT | CTA | 2 | 4 | B.1.599 | 0.007299 |
N | 3 | D3L | GAT | CTA | 2 | 4 | B.1.94 | 0.054054 |
N | 3 | D3L | GAT | CTA | 2 | 4 | P.1.13 | 0.001797 |
N | 3 | D3L | GAT | CTA | 3 | 4 | P.1.15 | 0.000697 |
N | 3 | D3L | GAT | CTA | 3 | 3 | AY.113 | 0.000427 |
N | 3 | D3L | GAT | CTA | 3 | 3 | AY.20 | 0.000117 |
N | 3 | D3L | GAT | CTA | 3 | 3 | AY.3 | 0.00003 |
N | 3 | D3L | GAT | CTA | 2 | 3 | AY.39.1 | 0.000079 |
N | 3 | D3L | GAT | CTA | 3 | 3 | B.1.1.318 | 0.000905 |
N | 3 | D3L | GAT | CTA | 3 | 3 | B.1.1.524 | 0.0625 |
N | 3 | D3L | GAT | CTA | 3 | 3 | B.1.1.525 | 0.016393 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.1.99 | 0.047619 |
N | 3 | D3L | GAT | CTA | 3 | 3 | B.1.170 | 0.012931 |
N | 3 | D3L | GAT | CTA | 3 | 3 | B.1.214.4 | 0.027273 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.524 | 0.002813 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.565 | 0.001621 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.577 | 0.001375 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.619 | 0.001742 |
N | 3 | D3L | GAT | CTA | 2 | 3 | B.1.620 | 0.001892 |
N | 3 | D3L | GAT | CTA | 3 | 3 | C.37 | 0.000348 |
N | 3 | D3L | GAT | CTA | 2 | 2 | AY.103 | 0.000012 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.13 | 0.000161 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.23 | 0.00007 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.34 | 0.000097 |
N | 3 | D3L | GAT | CTA | 2 | 2 | AY.39 | 0.000049 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.40 | 0.000964 |
N | 3 | D3L | GAT | CTA | 2 | 2 | AY.46 | 0.000208 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.75 | 0.000056 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.9.2 | 0.000037 |
N | 3 | D3L | GAT | CTA | 1 | 2 | AY.95 | 0.000761 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.171 | 0.003676 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.1.189 | 0.003026 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.216 | 0.00089 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.236 | 0.006897 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.1.315 | 0.016949 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.374 | 0.002375 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.389 | 0.006061 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.1.413 | 0.013793 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.1.464 | 0.001473 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.177.52 | 0.001757 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.177.67 | 0.007634 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.206 | 0.000816 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.237 | 0.00995 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.301 | 0.005917 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.367 | 0.001585 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.399 | 0.001934 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.432 | 0.011236 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.433 | 0.003195 |
N | 3 | D3L | GAT | CTA | 2 | 2 | B.1.517 | 0.000854 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.564 | 0.000426 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.627 | 0.00202 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.634 | 0.003425 |
N | 3 | D3L | GAT | CTA | 1 | 2 | B.1.636 | 0.006711 |
N | 3 | D3L | GAT | CTA | 2 | 2 | P.1.7 | 0.000639 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.100 | 0.000046 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.118 | 0.000063 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.2 | 0.000356 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.54 | 0.000095 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.68 | 0.000274 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.7 | 0.000196 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.77 | 0.001127 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.84 | 0.000437 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.9.1 | 0.000084 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AY.96 | 0.002075 |
N | 3 | D3L | GAT | CTA | 1 | 1 | AZ.2 | 0.000821 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.141 | 0.002012 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.254 | 0.011236 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.265 | 0.003155 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.280 | 0.003086 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.291 | 0.000742 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.301 | 0.001179 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.306 | 0.000438 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.33 | 0.000421 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.34 | 0.013158 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.340 | 0.045455 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.367 | 0.055556 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.372 | 0.000689 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.50 | 0.000679 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.51 | 0.001718 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.523 | 0.001563 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.526 | 0.003546 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.1.89 | 0.006061 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.140 | 0.018868 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.160.14 | 0.002119 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.160.16 | 0.000929 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.160.8 | 0.001289 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.177.31 | 0.011494 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.177.35 | 0.000691 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.177.81 | 0.000189 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.177.84 | 0.006667 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.179 | 0.003759 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.214.1 | 0.02 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.371 | 0.001122 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.415.1 | 0.007576 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.459 | 0.004082 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.462 | 0.007246 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.466.2 | 0.000391 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.533 | 0.009615 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.575 | 0.000303 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.590 | 0.004545 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.1.78 | 0.008547 |
N | 3 | D3L | GAT | CTA | 1 | 1 | B.6 | 0.00091 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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