CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 234 | M234I | nonsyn | atG | atC | 157953 | 38375 | 0.242952 | 28973-28975 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 234 | M234I | atG | atC | 38375 | 157953 | All | 0.00734 |
N | 234 | M234I | atG | atC | 29233 | 29464 | B.1.160 | 0.911708 |
N | 234 | M234I | atG | atC | 1 | 5446 | B.1.258.17 | 0.000104 |
N | 234 | M234I | atG | atC | 183 | 2555 | B.1 | 0.001676 |
N | 234 | M234I | atG | atC | 11 | 2477 | B.1.561 | 0.004367 |
N | 234 | M234I | atG | atC | 8 | 1386 | B.1.1 | 0.000145 |
N | 234 | M234I | atG | atC | 1327 | 1356 | AY.25 | 0.007982 |
N | 234 | M234I | atG | atC | 1047 | 1048 | B.1.160.16 | 0.973048 |
N | 234 | M234I | atG | atC | 775 | 775 | B.1.160.8 | 0.998711 |
N | 234 | M234I | atG | atC | 588 | 588 | B.1.160.17 | 1 |
N | 234 | M234I | atG | atC | 480 | 480 | B.1.160.7 | 0.997921 |
N | 234 | M234I | atG | atC | 9 | 466 | B.1.1.7 | 0.000008 |
N | 234 | M234I | atG | atC | 465 | 465 | B.1.160.14 | 0.985169 |
N | 234 | M234I | atG | atC | 24 | 425 | B.1.609 | 0.011505 |
N | 234 | M234I | atG | atC | 407 | 407 | B.1.160.26 | 0.985472 |
N | 234 | M234I | atG | atC | 7 | 407 | B.1.523 | 0.017157 |
N | 234 | M234I | atG | atC | 334 | 334 | B.1.160.28 | 0.976608 |
N | 234 | M234I | atG | atC | 2 | 316 | AY.44 | 0.000012 |
N | 234 | M234I | atG | atC | 38 | 278 | AY.4 | 0.000059 |
N | 234 | M234I | atG | atC | 5 | 255 | B.1.258 | 0.000333 |
N | 234 | M234I | atG | atC | 233 | 233 | B.1.160.29 | 0.983122 |
N | 234 | M234I | atG | atC | 225 | 225 | B.1.160.24 | 0.995575 |
N | 234 | M234I | atG | atC | 225 | 225 | B.1.160.33 | 0.995575 |
N | 234 | M234I | atG | atC | 4 | 224 | B.1.2 | 0.000035 |
N | 234 | M234I | atG | atC | 206 | 206 | B.1.160.23 | 0.995169 |
N | 234 | M234I | atG | atC | 198 | 198 | B.1.160.30 | 0.589286 |
N | 234 | M234I | atG | atC | 195 | 196 | B.1.160.15 | 0.965347 |
N | 234 | M234I | atG | atC | 11 | 193 | B.1.617.2 | 0.000041 |
N | 234 | M234I | atG | atC | 186 | 186 | B.1.160.32 | 0.798283 |
N | 234 | M234I | atG | atC | 174 | 174 | B.1.160.11 | 0.994286 |
N | 234 | M234I | atG | atC | 154 | 154 | B.1.160.12 | 0.987179 |
N | 234 | M234I | atG | atC | 146 | 146 | B.1.160.22 | 0.986486 |
N | 234 | M234I | atG | atC | 4 | 139 | B.1.36 | 0.000584 |
N | 234 | M234I | atG | atC | 138 | 138 | B.1.160.9 | 0.992806 |
N | 234 | M234I | atG | atC | 135 | 135 | B.1.160.18 | 0.985401 |
N | 234 | M234I | atG | atC | 124 | 124 | B.1.160.31 | 1 |
N | 234 | M234I | atG | atC | 121 | 121 | AB.1 | 0.991803 |
N | 234 | M234I | atG | atC | 114 | 114 | B.1.160.10 | 0.919355 |
N | 234 | M234I | atG | atC | 90 | 90 | B.1.160.25 | 1 |
N | 234 | M234I | atG | atC | 18 | 85 | P.1 | 0.000284 |
N | 234 | M234I | atG | atC | 81 | 82 | B.1.160.20 | 0.723214 |
N | 234 | M234I | atG | atC | 1 | 70 | B.1.1.50 | 0.000679 |
N | 234 | M234I | atG | atC | 57 | 68 | B.1.177 | 0.000751 |
N | 234 | M234I | atG | atC | 11 | 66 | AY.26 | 0.000311 |
N | 234 | M234I | atG | atC | 53 | 66 | B.1.221 | 0.003765 |
N | 234 | M234I | atG | atC | 65 | 65 | B.1.160.27 | 0.984848 |
N | 234 | M234I | atG | atC | 1 | 56 | AY.103 | 0.000006 |
N | 234 | M234I | atG | atC | 45 | 49 | B.1.1.39 | 0.022936 |
N | 234 | M234I | atG | atC | 49 | 49 | B.1.160.21 | 1 |
N | 234 | M234I | atG | atC | 1 | 49 | B.1.460 | 0.017857 |
N | 234 | M234I | atG | atC | 1 | 46 | AY.3 | 0.00001 |
N | 234 | M234I | atG | atC | 9 | 37 | B | 0.00115 |
N | 234 | M234I | atG | atC | 36 | 36 | B.1.160.13 | 1 |
N | 234 | M234I | atG | atC | 12 | 35 | B.1.177.73 | 0.006795 |
N | 234 | M234I | atG | atC | 5 | 30 | AY.43 | 0.000022 |
N | 234 | M234I | atG | atC | 30 | 30 | B.1.177.31 | 0.344828 |
N | 234 | M234I | atG | atC | 30 | 30 | B.1.177.44 | 0.015568 |
N | 234 | M234I | atG | atC | 28 | 28 | B.1.160.19 | 1 |
N | 234 | M234I | atG | atC | 26 | 26 | B.1.1.445 | 0.962963 |
N | 234 | M234I | atG | atC | 23 | 25 | B.1.1.265 | 0.072555 |
N | 234 | M234I | atG | atC | 21 | 21 | AY.64 | 0.0125 |
N | 234 | M234I | atG | atC | 1 | 21 | B.1.177.7 | 0.000165 |
N | 234 | M234I | atG | atC | 20 | 21 | B.1.258.11 | 0.007927 |
N | 234 | M234I | atG | atC | 1 | 21 | B.1.582 | 0.000491 |
N | 234 | M234I | atG | atC | 1 | 18 | B.1.567 | 0.003333 |
N | 234 | M234I | atG | atC | 1 | 14 | AY.102 | 0.000027 |
N | 234 | M234I | atG | atC | 1 | 12 | B.1.351 | 0.00003 |
N | 234 | M234I | atG | atC | 3 | 12 | B.1.36.29 | 0.001552 |
N | 234 | M234I | atG | atC | 3 | 11 | AY.23 | 0.000209 |
N | 234 | M234I | atG | atC | 1 | 11 | AY.61 | 0.000105 |
N | 234 | M234I | atG | atC | 2 | 11 | B.1.1.294 | 0.002532 |
N | 234 | M234I | atG | atC | 11 | 11 | B.1.177.43 | 0.016248 |
N | 234 | M234I | atG | atC | 10 | 10 | R.1 | 0.0009 |
N | 234 | M234I | atG | atC | 3 | 9 | AY.39 | 0.000074 |
N | 234 | M234I | atG | atC | 1 | 9 | B.1.214.2 | 0.0006 |
N | 234 | M234I | atG | atC | 6 | 9 | B.1.509 | 0.005195 |
N | 234 | M234I | atG | atC | 1 | 8 | AY.16 | 0.00038 |
N | 234 | M234I | atG | atC | 1 | 8 | AY.47 | 0.000031 |
N | 234 | M234I | atG | atC | 1 | 8 | B.1.1.216 | 0.00089 |
N | 234 | M234I | atG | atC | 4 | 8 | B.1.375 | 0.003279 |
N | 234 | M234I | atG | atC | 1 | 7 | A | 0.000387 |
N | 234 | M234I | atG | atC | 1 | 6 | AY.33 | 0.000067 |
N | 234 | M234I | atG | atC | 2 | 6 | B.1.409 | 0.001563 |
N | 234 | M234I | atG | atC | 5 | 5 | AY.116 | 0.001434 |
N | 234 | M234I | atG | atC | 2 | 5 | P.1.15 | 0.000465 |
N | 234 | M234I | atG | atC | 4 | 4 | B.1.260 | 0.013378 |
N | 234 | M234I | atG | atC | 4 | 4 | B.1.465 | 0.015209 |
N | 234 | M234I | atG | atC | 1 | 4 | B.1.468 | 0.005714 |
N | 234 | M234I | atG | atC | 4 | 4 | B.1.473 | 0.076923 |
N | 234 | M234I | atG | atC | 2 | 3 | AY.119 | 0.000071 |
N | 234 | M234I | atG | atC | 1 | 3 | AY.4.2 | 0.000022 |
N | 234 | M234I | atG | atC | 1 | 3 | B.1.157 | 0.002985 |
N | 234 | M234I | atG | atC | 2 | 2 | AY.117 | 0.000169 |
N | 234 | M234I | atG | atC | 2 | 2 | AY.7 | 0.000392 |
N | 234 | M234I | atG | atC | 2 | 2 | B.1.1.153 | 0.002191 |
N | 234 | M234I | atG | atC | 1 | 2 | B.1.1.37 | 0.000193 |
N | 234 | M234I | atG | atC | 2 | 2 | B.1.222 | 0.003384 |
N | 234 | M234I | atG | atC | 2 | 2 | B.1.36.22 | 0.002415 |
N | 234 | M234I | atG | atC | 2 | 2 | B.1.416.1 | 0.003125 |
N | 234 | M234I | atG | atC | 1 | 2 | B.1.428 | 0.00102 |
N | 234 | M234I | atG | atC | 1 | 2 | B.1.453 | 0.003236 |
N | 234 | M234I | atG | atC | 1 | 2 | B.1.599 | 0.00365 |
N | 234 | M234I | atG | atC | 2 | 2 | B.23 | 0.005848 |
N | 234 | M234I | atG | atC | 1 | 2 | C.16 | 0.00106 |
N | 234 | M234I | atG | atC | 1 | 1 | A.19 | 0.009434 |
N | 234 | M234I | atG | atC | 1 | 1 | AN.1 | 0.02 |
N | 234 | M234I | atG | atC | 1 | 1 | AY.69 | 0.000187 |
N | 234 | M234I | atG | atC | 1 | 1 | AY.7.2 | 0.000559 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.1.176 | 0.000439 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.1.236 | 0.006897 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.1.302 | 0.002075 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.1.381 | 0.04 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.1.70 | 0.000341 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.104 | 0.00369 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.124 | 0.007812 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.20 | 0.001517 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.21 | 0.000076 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.23 | 0.003236 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.32 | 0.00135 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.8 | 0.000752 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.177.85 | 0.005435 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.326 | 0.007576 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.36.25 | 0.002208 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.36.35 | 0.002604 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.36.8 | 0.001 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.378 | 0.006849 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.406 | 0.006061 |
N | 234 | M234I | atG | atC | 1 | 1 | B.1.474 | 0.001901 |
N | 234 | M234I | atG | atC | 1 | 1 | B.40 | 0.000364 |
N | 234 | M234I | atG | atC | 1 | 1 | C.18 | 0.002591 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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