CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 217 & Codon = Tct

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	217	A217S		nonsyn	Gct	Tct	2568	2567	0.999611	28922-28924

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	217	A217S	Gct	Tct	2567	2568	All	0.000491
N	217	A217S	Gct	Tct	436	436	AY.4	0.000679
N	217	A217S	Gct	Tct	224	224	AY.43	0.000992
N	217	A217S	Gct	Tct	213	213	B.1.618	0.858871
N	217	A217S	Gct	Tct	169	169	B.1.1.7	0.000151
N	217	A217S	Gct	Tct	133	133	B.1.617.2	0.000501
N	217	A217S	Gct	Tct	116	116	AY.12	0.036662
N	217	A217S	Gct	Tct	86	86	AY.103	0.000534
N	217	A217S	Gct	Tct	82	82	B.1.525	0.009279
N	217	A217S	Gct	Tct	81	81	AY.44	0.000493
N	217	A217S	Gct	Tct	75	75	AY.6	0.003085
N	217	A217S	Gct	Tct	69	69	B.1	0.000632
N	217	A217S	Gct	Tct	59	59	B.1.1.519	0.002343
N	217	A217S	Gct	Tct	51	51	AY.26	0.001444
N	217	A217S	Gct	Tct	37	37	AY.25	0.000223
N	217	A217S	Gct	Tct	36	36	AY.102	0.000955
N	217	A217S	Gct	Tct	31	31	AY.100	0.001426
N	217	A217S	Gct	Tct	30	30	AY.3	0.000298
N	217	A217S	Gct	Tct	29	29	AY.4.3	0.024411
N	217	A217S	Gct	Tct	27	27	AY.46.4	0.004442
N	217	A217S	Gct	Tct	27	27	B.1.2	0.000238
N	217	A217S	Gct	Tct	26	26	AY.39	0.000642
N	217	A217S	Gct	Tct	24	24	AY.98.1	0.001162
N	217	A217S	Gct	Tct	23	23	B.1.177.60	0.005024
N	217	A217S	Gct	Tct	21	21	AY.29	0.000331
N	217	A217S	Gct	Tct	19	19	B.1.1.214	0.001054
N	217	A217S	Gct	Tct	18	18	B.1.177	0.000237
N	217	A217S	Gct	Tct	18	18	B.1.582	0.008832
N	217	A217S	Gct	Tct	17	17	P.1	0.000268
N	217	A217S	Gct	Tct	16	16	AY.42	0.000644
N	217	A217S	Gct	Tct	13	13	AY.113	0.001851
N	217	A217S	Gct	Tct	11	11	B.1.346	0.014417
N	217	A217S	Gct	Tct	10	10	AY.9.2	0.000367
N	217	A217S	Gct	Tct	9	9	AY.109	0.006657
N	217	A217S	Gct	Tct	9	9	AY.4.2	0.000195
N	217	A217S	Gct	Tct	9	9	B.1.429	0.000212
N	217	A217S	Gct	Tct	8	8	AY.119	0.000282
N	217	A217S	Gct	Tct	8	8	AY.5	0.000165
N	217	A217S	Gct	Tct	8	8	B.1.1.294	0.010127
N	217	A217S	Gct	Tct	8	8	B.1.1.37	0.001543
N	217	A217S	Gct	Tct	8	8	B.1.637	0.000585
N	217	A217S	Gct	Tct	8	8	C.37	0.000929
N	217	A217S	Gct	Tct	7	7	AY.111	0.001282
N	217	A217S	Gct	Tct	7	7	AY.117	0.000592
N	217	A217S	Gct	Tct	7	7	AY.27	0.000453
N	217	A217S	Gct	Tct	7	7	B.1.450	0.079545
N	217	A217S	Gct	Tct	7	7	B.1.621	0.00062
N	217	A217S	Gct	Tct	6	6	AY.36	0.000889
N	217	A217S	Gct	Tct	6	6	B.1.1	0.000109
N	217	A217S	Gct	Tct	6	6	B.1.324	0.009631
N	217	A217S	Gct	Tct	6	6	B.1.36	0.000875
N	217	A217S	Gct	Tct	5	5	AY.120	0.000186
N	217	A217S	Gct	Tct	5	5	AY.20	0.000194
N	217	A217S	Gct	Tct	5	5	AY.47	0.000156
N	217	A217S	Gct	Tct	5	5	AY.61	0.000524
N	217	A217S	Gct	Tct	5	5	AY.68	0.001369
N	217	A217S	Gct	Tct	5	5	B.1.526	0.000118
N	217	A217S	Gct	Tct	4	4	AY.118	0.000251
N	217	A217S	Gct	Tct	4	4	AY.46	0.000416
N	217	A217S	Gct	Tct	4	4	AY.46.6	0.000289
N	217	A217S	Gct	Tct	4	4	AY.99.2	0.000369
N	217	A217S	Gct	Tct	4	4	B.1.1.74	0.017241
N	217	A217S	Gct	Tct	4	4	B.1.351	0.000119
N	217	A217S	Gct	Tct	4	4	B.6.6	0.003556
N	217	A217S	Gct	Tct	3	3	AY.121	0.000406
N	217	A217S	Gct	Tct	3	3	AY.23	0.000209
N	217	A217S	Gct	Tct	3	3	AY.33	0.0002
N	217	A217S	Gct	Tct	3	3	AY.4.5	0.000322
N	217	A217S	Gct	Tct	3	3	AY.45	0.000365
N	217	A217S	Gct	Tct	3	3	AY.46.5	0.000595
N	217	A217S	Gct	Tct	3	3	AY.7.2	0.001678
N	217	A217S	Gct	Tct	3	3	AY.77	0.003382
N	217	A217S	Gct	Tct	3	3	AY.98	0.000237
N	217	A217S	Gct	Tct	3	3	B.1.177.46	0.002755
N	217	A217S	Gct	Tct	3	3	B.1.177.58	0.003995
N	217	A217S	Gct	Tct	2	3	B.1.221	0.000142
N	217	A217S	Gct	Tct	3	3	B.1.595	0.000783
N	217	A217S	Gct	Tct	2	2	AY.34	0.000194
N	217	A217S	Gct	Tct	2	2	AY.39.1	0.000079
N	217	A217S	Gct	Tct	2	2	AY.50	0.001599
N	217	A217S	Gct	Tct	2	2	AY.54	0.000191
N	217	A217S	Gct	Tct	2	2	AY.78	0.003082
N	217	A217S	Gct	Tct	2	2	AY.82	0.002714
N	217	A217S	Gct	Tct	2	2	AY.92	0.000575
N	217	A217S	Gct	Tct	2	2	B.1.1.194	0.009901
N	217	A217S	Gct	Tct	2	2	B.1.1.216	0.001781
N	217	A217S	Gct	Tct	2	2	B.1.1.291	0.001485
N	217	A217S	Gct	Tct	2	2	B.1.1.448	0.004065
N	217	A217S	Gct	Tct	2	2	B.1.160	0.000062
N	217	A217S	Gct	Tct	2	2	B.1.22	0.002635
N	217	A217S	Gct	Tct	2	2	B.1.258	0.000133
N	217	A217S	Gct	Tct	2	2	B.1.258.17	0.000208
N	217	A217S	Gct	Tct	2	2	B.1.311	0.000549
N	217	A217S	Gct	Tct	2	2	B.1.36.31	0.003503
N	217	A217S	Gct	Tct	2	2	B.1.427	0.000101
N	217	A217S	Gct	Tct	2	2	B.1.575	0.000607
N	217	A217S	Gct	Tct	2	2	B.1.596	0.000174
N	217	A217S	Gct	Tct	2	2	B.47	0.040816
N	217	A217S	Gct	Tct	2	2	C.36	0.001821
N	217	A217S	Gct	Tct	2	2	P.1.15	0.000465
N	217	A217S	Gct	Tct	1	1	A.19	0.009434
N	217	A217S	Gct	Tct	1	1	A.2.2	0.001689
N	217	A217S	Gct	Tct	1	1	A.29	0.005319
N	217	A217S	Gct	Tct	1	1	AY.1	0.000396
N	217	A217S	Gct	Tct	1	1	AY.10	0.00053
N	217	A217S	Gct	Tct	1	1	AY.105	0.000643
N	217	A217S	Gct	Tct	1	1	AY.108	0.001103
N	217	A217S	Gct	Tct	1	1	AY.116	0.000287
N	217	A217S	Gct	Tct	1	1	AY.120.1	0.000321
N	217	A217S	Gct	Tct	1	1	AY.29.1	0.000221
N	217	A217S	Gct	Tct	1	1	AY.30	0.000396
N	217	A217S	Gct	Tct	1	1	AY.39.2	0.001541
N	217	A217S	Gct	Tct	1	1	AY.5.3	0.000337
N	217	A217S	Gct	Tct	1	1	AY.5.4	0.000277
N	217	A217S	Gct	Tct	1	1	AY.51	0.000909
N	217	A217S	Gct	Tct	1	1	AY.55	0.000917
N	217	A217S	Gct	Tct	1	1	AY.57	0.000656
N	217	A217S	Gct	Tct	1	1	AY.60	0.000938
N	217	A217S	Gct	Tct	1	1	AY.64	0.000595
N	217	A217S	Gct	Tct	1	1	AY.69	0.000187
N	217	A217S	Gct	Tct	1	1	AY.7.1	0.000113
N	217	A217S	Gct	Tct	1	1	AY.70	0.000209
N	217	A217S	Gct	Tct	1	1	AY.71	0.000475
N	217	A217S	Gct	Tct	1	1	AY.75.1	0.00018
N	217	A217S	Gct	Tct	1	1	AY.9	0.000068
N	217	A217S	Gct	Tct	1	1	AY.9.1	0.000084
N	217	A217S	Gct	Tct	1	1	AY.91	0.00073
N	217	A217S	Gct	Tct	1	1	AY.94	0.000443
N	217	A217S	Gct	Tct	1	1	AY.99	0.001049
N	217	A217S	Gct	Tct	1	1	B.1.1.1	0.000327
N	217	A217S	Gct	Tct	1	1	B.1.1.153	0.001095
N	217	A217S	Gct	Tct	1	1	B.1.1.176	0.000439
N	217	A217S	Gct	Tct	1	1	B.1.1.213	0.021739
N	217	A217S	Gct	Tct	1	1	B.1.1.222	0.000204
N	217	A217S	Gct	Tct	1	1	B.1.1.243	0.004082
N	217	A217S	Gct	Tct	1	1	B.1.1.306	0.000438
N	217	A217S	Gct	Tct	1	1	B.1.1.325	0.025641
N	217	A217S	Gct	Tct	1	1	B.1.1.326	0.001761
N	217	A217S	Gct	Tct	1	1	B.1.1.348	0.000796
N	217	A217S	Gct	Tct	1	1	B.1.1.373	0.02381
N	217	A217S	Gct	Tct	1	1	B.1.1.389	0.006061
N	217	A217S	Gct	Tct	1	1	B.1.1.434	0.000349
N	217	A217S	Gct	Tct	1	1	B.1.1.50	0.000679
N	217	A217S	Gct	Tct	1	1	B.1.112	0.005181
N	217	A217S	Gct	Tct	1	1	B.1.177.12	0.000152
N	217	A217S	Gct	Tct	1	1	B.1.177.15	0.000631
N	217	A217S	Gct	Tct	1	1	B.1.177.75	0.001041
N	217	A217S	Gct	Tct	1	1	B.1.177.77	0.000726
N	217	A217S	Gct	Tct	1	1	B.1.177.8	0.000752
N	217	A217S	Gct	Tct	1	1	B.1.177.82	0.000477
N	217	A217S	Gct	Tct	1	1	B.1.188	0.016667
N	217	A217S	Gct	Tct	1	1	B.1.221.2	0.004016
N	217	A217S	Gct	Tct	1	1	B.1.234	0.000132
N	217	A217S	Gct	Tct	1	1	B.1.314	0.007519
N	217	A217S	Gct	Tct	1	1	B.1.389	0.001002
N	217	A217S	Gct	Tct	1	1	B.1.391	0.001127
N	217	A217S	Gct	Tct	1	1	B.1.527	0.003704
N	217	A217S	Gct	Tct	1	1	B.1.576	0.000907
N	217	A217S	Gct	Tct	1	1	B.1.619.1	0.000641
N	217	A217S	Gct	Tct	1	1	B.1.631	0.003367
N	217	A217S	Gct	Tct	1	1	P.1.12	0.000484
N	217	A217S	Gct	Tct	1	1	P.1.7	0.000319
N	217	A217S	Gct	Tct	1	1	P.2	0.000187
N	217	A217S	Gct	Tct	1	1	Q.7	0.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.