CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 198 | T198I | nonsyn | aCt | aTt | 1395 | 1395 | 1 | 28865-28867 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 198 | T198I | aCt | aTt | 1395 | 1395 | All | 0.000267 |
N | 198 | T198I | aCt | aTt | 264 | 264 | B.1.469 | 0.953069 |
N | 198 | T198I | aCt | aTt | 215 | 215 | AY.4 | 0.000335 |
N | 198 | T198I | aCt | aTt | 115 | 115 | B.1.1.7 | 0.000103 |
N | 198 | T198I | aCt | aTt | 87 | 87 | AY.103 | 0.00054 |
N | 198 | T198I | aCt | aTt | 87 | 87 | B.1 | 0.000797 |
N | 198 | T198I | aCt | aTt | 63 | 63 | B.1.617.2 | 0.000237 |
N | 198 | T198I | aCt | aTt | 55 | 55 | AY.43 | 0.000244 |
N | 198 | T198I | aCt | aTt | 51 | 51 | B.1.223 | 0.141667 |
N | 198 | T198I | aCt | aTt | 45 | 45 | AY.102 | 0.001193 |
N | 198 | T198I | aCt | aTt | 31 | 31 | B.1.1 | 0.000562 |
N | 198 | T198I | aCt | aTt | 30 | 30 | P.1.1 | 0.00953 |
N | 198 | T198I | aCt | aTt | 22 | 22 | B.1.1.348 | 0.017516 |
N | 198 | T198I | aCt | aTt | 18 | 18 | B.1.2 | 0.000158 |
N | 198 | T198I | aCt | aTt | 17 | 17 | B.1.139 | 0.012463 |
N | 198 | T198I | aCt | aTt | 16 | 16 | AY.44 | 0.000097 |
N | 198 | T198I | aCt | aTt | 16 | 16 | P.1 | 0.000252 |
N | 198 | T198I | aCt | aTt | 12 | 12 | B.1.258.17 | 0.001248 |
N | 198 | T198I | aCt | aTt | 10 | 10 | B.1.1.318 | 0.003018 |
N | 198 | T198I | aCt | aTt | 8 | 8 | AY.118 | 0.000501 |
N | 198 | T198I | aCt | aTt | 8 | 8 | AY.20 | 0.000311 |
N | 198 | T198I | aCt | aTt | 8 | 8 | B.1.177 | 0.000105 |
N | 198 | T198I | aCt | aTt | 8 | 8 | B.1.637 | 0.000585 |
N | 198 | T198I | aCt | aTt | 7 | 7 | AY.39 | 0.000173 |
N | 198 | T198I | aCt | aTt | 7 | 7 | AY.5 | 0.000145 |
N | 198 | T198I | aCt | aTt | 7 | 7 | B.1.1.25 | 0.00398 |
N | 198 | T198I | aCt | aTt | 7 | 7 | B.1.36 | 0.001021 |
N | 198 | T198I | aCt | aTt | 7 | 7 | B.1.480 | 0.017413 |
N | 198 | T198I | aCt | aTt | 6 | 6 | AY.119 | 0.000212 |
N | 198 | T198I | aCt | aTt | 6 | 6 | B.1.243 | 0.000418 |
N | 198 | T198I | aCt | aTt | 6 | 6 | B.1.466.2 | 0.002347 |
N | 198 | T198I | aCt | aTt | 5 | 5 | B.1.1.277 | 0.003794 |
N | 198 | T198I | aCt | aTt | 5 | 5 | B.1.258.9 | 0.025 |
N | 198 | T198I | aCt | aTt | 5 | 5 | B.40 | 0.001821 |
N | 198 | T198I | aCt | aTt | 5 | 5 | D.2 | 0.000375 |
N | 198 | T198I | aCt | aTt | 4 | 4 | AY.121 | 0.000541 |
N | 198 | T198I | aCt | aTt | 4 | 4 | AY.14 | 0.000352 |
N | 198 | T198I | aCt | aTt | 4 | 4 | AY.29 | 0.000063 |
N | 198 | T198I | aCt | aTt | 4 | 4 | AY.74 | 0.000463 |
N | 198 | T198I | aCt | aTt | 4 | 4 | B.1.160.10 | 0.032258 |
N | 198 | T198I | aCt | aTt | 4 | 4 | C.36.2 | 0.137931 |
N | 198 | T198I | aCt | aTt | 3 | 3 | AY.25 | 0.000018 |
N | 198 | T198I | aCt | aTt | 3 | 3 | AY.3 | 0.00003 |
N | 198 | T198I | aCt | aTt | 3 | 3 | AY.47 | 0.000093 |
N | 198 | T198I | aCt | aTt | 3 | 3 | AY.54 | 0.000286 |
N | 198 | T198I | aCt | aTt | 3 | 3 | B.1.195 | 0.015075 |
N | 198 | T198I | aCt | aTt | 3 | 3 | B.1.210 | 0.006397 |
N | 198 | T198I | aCt | aTt | 3 | 3 | B.1.221 | 0.000213 |
N | 198 | T198I | aCt | aTt | 3 | 3 | B.1.462 | 0.021739 |
N | 198 | T198I | aCt | aTt | 3 | 3 | C.36.3 | 0.001702 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.30 | 0.000791 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.37 | 0.000632 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.42 | 0.00008 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.45 | 0.000243 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.46 | 0.000208 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.86 | 0.00166 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.9 | 0.000135 |
N | 198 | T198I | aCt | aTt | 2 | 2 | AY.9.2 | 0.000073 |
N | 198 | T198I | aCt | aTt | 2 | 2 | B | 0.000256 |
N | 198 | T198I | aCt | aTt | 2 | 2 | B.1.258 | 0.000133 |
N | 198 | T198I | aCt | aTt | 2 | 2 | B.1.9 | 0.012346 |
N | 198 | T198I | aCt | aTt | 2 | 2 | P.1.15 | 0.000465 |
N | 198 | T198I | aCt | aTt | 1 | 1 | A.2.5 | 0.000499 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.111 | 0.000183 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.113 | 0.000142 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.114 | 0.000231 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.120 | 0.000037 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.16 | 0.00038 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.23 | 0.00007 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.23.1 | 0.000417 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.24 | 0.000431 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.26 | 0.000028 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.29.1 | 0.000221 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.4.2 | 0.000022 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.4.5 | 0.000107 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.46.2 | 0.000635 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.46.4 | 0.000165 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.46.6 | 0.000072 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.5.3 | 0.000337 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.5.4 | 0.000277 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.52 | 0.000814 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.58 | 0.000907 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.6 | 0.000041 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.75 | 0.000056 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.75.1 | 0.00018 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.98 | 0.000079 |
N | 198 | T198I | aCt | aTt | 1 | 1 | AY.99.2 | 0.000092 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.1 | 0.000327 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.176 | 0.000439 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.28 | 0.000311 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.306 | 0.000438 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.317 | 0.000412 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.466 | 0.008696 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.519 | 0.00004 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.1.70 | 0.000341 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.110.3 | 0.000718 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.160.20 | 0.008929 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.177.77 | 0.000726 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.232 | 0.000537 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.240 | 0.000216 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.276 | 0.016949 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.281 | 0.021739 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.311 | 0.000275 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.337 | 0.005587 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.351 | 0.00003 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.367 | 0.000792 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.396 | 0.000706 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.420 | 0.010417 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.428 | 0.00102 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.561 | 0.000397 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.576 | 0.000907 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.578 | 0.017857 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.582 | 0.000491 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.588 | 0.00091 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.595.1 | 0.005848 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.596 | 0.000087 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.1.602 | 0.006536 |
N | 198 | T198I | aCt | aTt | 1 | 1 | B.3 | 0.000831 |
N | 198 | T198I | aCt | aTt | 1 | 1 | P.1.17 | 0.000162 |
N | 198 | T198I | aCt | aTt | 1 | 1 | P.1.2 | 0.001156 |
N | 198 | T198I | aCt | aTt | 1 | 1 | P.1.7 | 0.000319 |
N | 198 | T198I | aCt | aTt | 1 | 1 | Q.1 | 0.000126 |
N | 198 | T198I | aCt | aTt | 1 | 1 | R.1 | 0.00009 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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