CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 175 & Codon = ggT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	175	G175G		syn	ggG	ggT	4326	2907	0.671983	28796-28798

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	175	G175G	ggG	ggT	2907	4326	All	0.000556
N	175	G175G	ggG	ggT	2169	2170	AY.5	0.044788
N	175	G175G	ggG	ggT	73	818	B.1.1.7	0.000065
N	175	G175G	ggG	ggT	56	188	AY.4	0.000087
N	175	G175G	ggG	ggT	71	98	B.1.617.2	0.000267
N	175	G175G	ggG	ggT	71	71	AY.5.3	0.023954
N	175	G175G	ggG	ggT	8	60	AY.103	0.00005
N	175	G175G	ggG	ggT	59	60	AY.29	0.000931
N	175	G175G	ggG	ggT	43	49	AY.46	0.004475
N	175	G175G	ggG	ggT	46	46	AY.108	0.050717
N	175	G175G	ggG	ggT	29	45	B.1	0.000266
N	175	G175G	ggG	ggT	3	44	AY.26	0.000085
N	175	G175G	ggG	ggT	14	41	AY.44	0.000085
N	175	G175G	ggG	ggT	27	37	B.1.2	0.000238
N	175	G175G	ggG	ggT	32	32	P.1.14	0.00153
N	175	G175G	ggG	ggT	6	29	AY.25	0.000036
N	175	G175G	ggG	ggT	8	29	AY.3	0.00008
N	175	G175G	ggG	ggT	22	22	B.1.1.170	0.027431
N	175	G175G	ggG	ggT	12	21	B.1.427	0.000606
N	175	G175G	ggG	ggT	13	20	AY.43	0.000058
N	175	G175G	ggG	ggT	13	20	B.1.177	0.000171
N	175	G175G	ggG	ggT	8	19	AY.47	0.000249
N	175	G175G	ggG	ggT	17	17	AY.120	0.000632
N	175	G175G	ggG	ggT	17	17	AY.98	0.001343
N	175	G175G	ggG	ggT	7	16	AY.102	0.000186
N	175	G175G	ggG	ggT	3	16	P.1	0.000047
N	175	G175G	ggG	ggT	1	11	B.1.351	0.00003
N	175	G175G	ggG	ggT	8	9	AY.42	0.000322
N	175	G175G	ggG	ggT	2	9	B.1.429	0.000047
N	175	G175G	ggG	ggT	1	6	B.1.160	0.000031
N	175	G175G	ggG	ggT	6	6	B.1.507	0.067416
N	175	G175G	ggG	ggT	3	5	AY.119	0.000106
N	175	G175G	ggG	ggT	1	5	AY.20	0.000039
N	175	G175G	ggG	ggT	3	5	AY.39	0.000074
N	175	G175G	ggG	ggT	1	5	B.1.526	0.000024
N	175	G175G	ggG	ggT	2	5	C.37	0.000232
N	175	G175G	ggG	ggT	4	4	AY.54	0.000381
N	175	G175G	ggG	ggT	1	4	B.1.621	0.000089
N	175	G175G	ggG	ggT	3	3	AY.23	0.000209
N	175	G175G	ggG	ggT	2	3	AY.4.2	0.000043
N	175	G175G	ggG	ggT	3	3	AY.45	0.000365
N	175	G175G	ggG	ggT	3	3	AY.69	0.00056
N	175	G175G	ggG	ggT	3	3	AY.9	0.000203
N	175	G175G	ggG	ggT	2	3	B.1.221	0.000142
N	175	G175G	ggG	ggT	2	2	AE.1	0.022727
N	175	G175G	ggG	ggT	2	2	AY.121	0.000271
N	175	G175G	ggG	ggT	2	2	AY.33	0.000134
N	175	G175G	ggG	ggT	2	2	AY.73	0.001331
N	175	G175G	ggG	ggT	2	2	B.1.177.73	0.001133
N	175	G175G	ggG	ggT	1	2	D.2	0.000075
N	175	G175G	ggG	ggT	1	1	A	0.000387
N	175	G175G	ggG	ggT	1	1	AY.12	0.000316
N	175	G175G	ggG	ggT	1	1	AY.34.1	0.00051
N	175	G175G	ggG	ggT	1	1	AY.36	0.000148
N	175	G175G	ggG	ggT	1	1	AY.4.3	0.000842
N	175	G175G	ggG	ggT	1	1	AY.46.6	0.000072
N	175	G175G	ggG	ggT	1	1	AY.5.4	0.000277
N	175	G175G	ggG	ggT	1	1	AY.52	0.000814
N	175	G175G	ggG	ggT	1	1	AY.84	0.000437
N	175	G175G	ggG	ggT	1	1	AY.88	0.000884
N	175	G175G	ggG	ggT	1	1	AY.9.2	0.000037
N	175	G175G	ggG	ggT	1	1	AY.93	0.000273
N	175	G175G	ggG	ggT	1	1	B	0.000128
N	175	G175G	ggG	ggT	1	1	B.1.1.25	0.000569
N	175	G175G	ggG	ggT	1	1	B.1.1.413	0.006897
N	175	G175G	ggG	ggT	1	1	B.1.177.12	0.000152
N	175	G175G	ggG	ggT	1	1	B.1.346	0.001311
N	175	G175G	ggG	ggT	1	1	B.1.36.18	0.00042
N	175	G175G	ggG	ggT	1	1	B.1.462	0.007246
N	175	G175G	ggG	ggT	1	1	B.1.582	0.000491

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.