CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 16 | T16T | syn | acG | acA | 6743 | 2063 | 0.305947 | 28319-28321 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 16 | T16T | acG | acA | 2063 | 6743 | All | 0.000395 |
N | 16 | T16T | acG | acA | 1132 | 1132 | B.1.177.10 | 0.993854 |
N | 16 | T16T | acG | acA | 63 | 1130 | B.1.1.7 | 0.000056 |
N | 16 | T16T | acG | acA | 29 | 893 | AY.4 | 0.000045 |
N | 16 | T16T | acG | acA | 72 | 176 | B.1.2 | 0.000634 |
N | 16 | T16T | acG | acA | 54 | 175 | B.1 | 0.000495 |
N | 16 | T16T | acG | acA | 8 | 146 | B.1.617.2 | 0.00003 |
N | 16 | T16T | acG | acA | 37 | 119 | B.1.177 | 0.000487 |
N | 16 | T16T | acG | acA | 71 | 115 | B.1.1 | 0.001288 |
N | 16 | T16T | acG | acA | 1 | 114 | AY.74 | 0.000116 |
N | 16 | T16T | acG | acA | 79 | 105 | B.1.429 | 0.001859 |
N | 16 | T16T | acG | acA | 1 | 95 | B.1.1.50 | 0.000679 |
N | 16 | T16T | acG | acA | 10 | 87 | AY.103 | 0.000062 |
N | 16 | T16T | acG | acA | 8 | 77 | AY.43 | 0.000035 |
N | 16 | T16T | acG | acA | 9 | 67 | AY.3 | 0.00009 |
N | 16 | T16T | acG | acA | 10 | 64 | P.1 | 0.000158 |
N | 16 | T16T | acG | acA | 9 | 60 | B.1.160 | 0.000281 |
N | 16 | T16T | acG | acA | 12 | 52 | AY.25 | 0.000072 |
N | 16 | T16T | acG | acA | 40 | 52 | B.1.1.519 | 0.001588 |
N | 16 | T16T | acG | acA | 5 | 51 | AY.44 | 0.00003 |
N | 16 | T16T | acG | acA | 34 | 39 | B.1.1.1 | 0.011107 |
N | 16 | T16T | acG | acA | 2 | 32 | AY.46.6 | 0.000144 |
N | 16 | T16T | acG | acA | 27 | 31 | B.1.1.63 | 0.010417 |
N | 16 | T16T | acG | acA | 29 | 29 | B.1.1.434 | 0.010108 |
N | 16 | T16T | acG | acA | 28 | 29 | B.1.466.2 | 0.010955 |
N | 16 | T16T | acG | acA | 5 | 27 | B.1.351 | 0.000149 |
N | 16 | T16T | acG | acA | 24 | 24 | B.1.1.70 | 0.008186 |
N | 16 | T16T | acG | acA | 1 | 24 | B.1.243 | 0.00007 |
N | 16 | T16T | acG | acA | 14 | 21 | B.1.1.216 | 0.012467 |
N | 16 | T16T | acG | acA | 13 | 20 | B.1.258 | 0.000865 |
N | 16 | T16T | acG | acA | 1 | 20 | B.1.526 | 0.000024 |
N | 16 | T16T | acG | acA | 17 | 19 | B.1.1.305 | 0.065637 |
N | 16 | T16T | acG | acA | 3 | 16 | AY.121 | 0.000406 |
N | 16 | T16T | acG | acA | 4 | 14 | AY.4.2 | 0.000087 |
N | 16 | T16T | acG | acA | 11 | 14 | AY.98 | 0.000869 |
N | 16 | T16T | acG | acA | 10 | 13 | P.1.14 | 0.000478 |
N | 16 | T16T | acG | acA | 2 | 11 | AY.6 | 0.000082 |
N | 16 | T16T | acG | acA | 11 | 11 | B.1.527 | 0.040741 |
N | 16 | T16T | acG | acA | 1 | 9 | AY.118 | 0.000063 |
N | 16 | T16T | acG | acA | 1 | 9 | AY.29 | 0.000016 |
N | 16 | T16T | acG | acA | 1 | 9 | AY.75 | 0.000056 |
N | 16 | T16T | acG | acA | 9 | 9 | B.1.177.72 | 0.030508 |
N | 16 | T16T | acG | acA | 1 | 9 | B.1.396 | 0.000706 |
N | 16 | T16T | acG | acA | 3 | 8 | AY.9.2 | 0.00011 |
N | 16 | T16T | acG | acA | 8 | 8 | B.1.1.354 | 0.035088 |
N | 16 | T16T | acG | acA | 3 | 8 | B.1.36 | 0.000438 |
N | 16 | T16T | acG | acA | 1 | 7 | AY.48 | 0.000465 |
N | 16 | T16T | acG | acA | 1 | 7 | AY.61 | 0.000105 |
N | 16 | T16T | acG | acA | 1 | 6 | AY.20 | 0.000039 |
N | 16 | T16T | acG | acA | 6 | 6 | B.1.1.265 | 0.018927 |
N | 16 | T16T | acG | acA | 6 | 6 | B.1.1.291 | 0.004454 |
N | 16 | T16T | acG | acA | 6 | 6 | B.1.36.26 | 0.017143 |
N | 16 | T16T | acG | acA | 2 | 6 | P.1.15 | 0.000465 |
N | 16 | T16T | acG | acA | 4 | 5 | B.1.1.25 | 0.002274 |
N | 16 | T16T | acG | acA | 2 | 5 | B.1.525 | 0.000226 |
N | 16 | T16T | acG | acA | 2 | 5 | B.1.621 | 0.000177 |
N | 16 | T16T | acG | acA | 4 | 4 | AY.114 | 0.000924 |
N | 16 | T16T | acG | acA | 1 | 4 | AY.46 | 0.000104 |
N | 16 | T16T | acG | acA | 1 | 4 | AY.47 | 0.000031 |
N | 16 | T16T | acG | acA | 3 | 4 | AY.77 | 0.003382 |
N | 16 | T16T | acG | acA | 4 | 4 | B.1.1.28 | 0.001245 |
N | 16 | T16T | acG | acA | 1 | 4 | B.1.1.448 | 0.002033 |
N | 16 | T16T | acG | acA | 4 | 4 | B.1.1.526 | 0.014184 |
N | 16 | T16T | acG | acA | 4 | 4 | B.1.111 | 0.0047 |
N | 16 | T16T | acG | acA | 1 | 4 | B.1.36.29 | 0.000517 |
N | 16 | T16T | acG | acA | 4 | 4 | B.1.36.9 | 0.012862 |
N | 16 | T16T | acG | acA | 2 | 4 | B.1.582 | 0.000981 |
N | 16 | T16T | acG | acA | 2 | 3 | A.23.1 | 0.001408 |
N | 16 | T16T | acG | acA | 2 | 3 | AY.111 | 0.000366 |
N | 16 | T16T | acG | acA | 3 | 3 | AY.29.1 | 0.000662 |
N | 16 | T16T | acG | acA | 1 | 3 | AY.34 | 0.000097 |
N | 16 | T16T | acG | acA | 3 | 3 | AY.7.2 | 0.001678 |
N | 16 | T16T | acG | acA | 2 | 3 | B.1.1.277 | 0.001517 |
N | 16 | T16T | acG | acA | 1 | 3 | B.1.1.317 | 0.000412 |
N | 16 | T16T | acG | acA | 3 | 3 | B.1.1.368 | 0.009259 |
N | 16 | T16T | acG | acA | 2 | 3 | B.1.177.73 | 0.001133 |
N | 16 | T16T | acG | acA | 2 | 3 | B.1.177.8 | 0.001505 |
N | 16 | T16T | acG | acA | 1 | 3 | B.1.36.18 | 0.00042 |
N | 16 | T16T | acG | acA | 1 | 3 | B.1.595 | 0.000261 |
N | 16 | T16T | acG | acA | 3 | 3 | B.40 | 0.001093 |
N | 16 | T16T | acG | acA | 2 | 3 | C.36 | 0.001821 |
N | 16 | T16T | acG | acA | 2 | 2 | AY.39.1 | 0.000079 |
N | 16 | T16T | acG | acA | 1 | 2 | AY.69 | 0.000187 |
N | 16 | T16T | acG | acA | 1 | 2 | AY.75.1 | 0.00018 |
N | 16 | T16T | acG | acA | 1 | 2 | B.1.1.141 | 0.002012 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.1.159 | 0.009346 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.1.198 | 0.002937 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.1.378 | 0.014599 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.1.432 | 0.002532 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.192 | 0.018519 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.201 | 0.011364 |
N | 16 | T16T | acG | acA | 1 | 2 | B.1.258.17 | 0.000104 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.36.10 | 0.009569 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.466.1 | 0.014388 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.524 | 0.002813 |
N | 16 | T16T | acG | acA | 2 | 2 | B.1.609 | 0.000959 |
N | 16 | T16T | acG | acA | 2 | 2 | C.16 | 0.002121 |
N | 16 | T16T | acG | acA | 2 | 2 | C.23 | 0.011628 |
N | 16 | T16T | acG | acA | 1 | 2 | P.1.17 | 0.000162 |
N | 16 | T16T | acG | acA | 1 | 2 | Q.3 | 0.000145 |
N | 16 | T16T | acG | acA | 1 | 1 | A.19 | 0.009434 |
N | 16 | T16T | acG | acA | 1 | 1 | AY.108 | 0.001103 |
N | 16 | T16T | acG | acA | 1 | 1 | AY.4.1 | 0.000737 |
N | 16 | T16T | acG | acA | 1 | 1 | AY.5.4 | 0.000277 |
N | 16 | T16T | acG | acA | 1 | 1 | B | 0.000128 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.220 | 0.001859 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.222 | 0.000204 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.273 | 0.006757 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.306 | 0.000438 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.369 | 0.000446 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.37 | 0.000193 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.372 | 0.000689 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.420 | 0.001006 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.46 | 0.004367 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.521 | 0.005348 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.1.58 | 0.005376 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.177.23 | 0.003236 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.177.42 | 0.000894 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.314 | 0.007519 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.320 | 0.001245 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.351.3 | 0.000876 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.36.8 | 0.001 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.381 | 0.007812 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.425 | 0.002994 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.497 | 0.000315 |
N | 16 | T16T | acG | acA | 1 | 1 | B.1.9.4 | 0.006135 |
N | 16 | T16T | acG | acA | 1 | 1 | C.33 | 0.058824 |
N | 16 | T16T | acG | acA | 1 | 1 | C.9 | 0.030303 |
N | 16 | T16T | acG | acA | 1 | 1 | N.6 | 0.007092 |
N | 16 | T16T | acG | acA | 1 | 1 | P.1.12 | 0.000484 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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