CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
N | 16 | T16M | nonsyn | aCg | aTg | 2406 | 2406 | 1 | 28319-28321 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
N | 16 | T16M | aCg | aTg | 2406 | 2406 | All | 0.00046 |
N | 16 | T16M | aCg | aTg | 377 | 377 | B.1.1.7 | 0.000337 |
N | 16 | T16M | aCg | aTg | 347 | 347 | AY.44 | 0.002112 |
N | 16 | T16M | aCg | aTg | 240 | 240 | B.1.2 | 0.002113 |
N | 16 | T16M | aCg | aTg | 121 | 121 | AY.4 | 0.000188 |
N | 16 | T16M | aCg | aTg | 115 | 115 | B.1.362 | 0.177196 |
N | 16 | T16M | aCg | aTg | 101 | 101 | AY.43 | 0.000447 |
N | 16 | T16M | aCg | aTg | 94 | 94 | B.1.617.2 | 0.000354 |
N | 16 | T16M | aCg | aTg | 72 | 72 | B.1 | 0.000659 |
N | 16 | T16M | aCg | aTg | 69 | 69 | AY.103 | 0.000428 |
N | 16 | T16M | aCg | aTg | 51 | 51 | B.1.1 | 0.000925 |
N | 16 | T16M | aCg | aTg | 39 | 39 | B.1.177 | 0.000514 |
N | 16 | T16M | aCg | aTg | 38 | 38 | B.1.429 | 0.000894 |
N | 16 | T16M | aCg | aTg | 36 | 36 | AY.7.1 | 0.004057 |
N | 16 | T16M | aCg | aTg | 29 | 29 | AY.47 | 0.000902 |
N | 16 | T16M | aCg | aTg | 25 | 25 | AY.25 | 0.00015 |
N | 16 | T16M | aCg | aTg | 24 | 24 | AY.3 | 0.000239 |
N | 16 | T16M | aCg | aTg | 24 | 24 | B.1.351 | 0.000713 |
N | 16 | T16M | aCg | aTg | 23 | 23 | AY.4.2 | 0.000499 |
N | 16 | T16M | aCg | aTg | 21 | 21 | B.1.1.284 | 0.002255 |
N | 16 | T16M | aCg | aTg | 21 | 21 | B.1.596 | 0.00183 |
N | 16 | T16M | aCg | aTg | 20 | 20 | B.1.311 | 0.005491 |
N | 16 | T16M | aCg | aTg | 19 | 19 | B.1.177.36 | 0.306452 |
N | 16 | T16M | aCg | aTg | 18 | 18 | B.1.160 | 0.000561 |
N | 16 | T16M | aCg | aTg | 17 | 17 | B.1.177.86 | 0.003119 |
N | 16 | T16M | aCg | aTg | 17 | 17 | P.1 | 0.000268 |
N | 16 | T16M | aCg | aTg | 16 | 16 | B.1.36.29 | 0.008277 |
N | 16 | T16M | aCg | aTg | 14 | 14 | AY.111 | 0.002564 |
N | 16 | T16M | aCg | aTg | 13 | 13 | AY.35 | 0.00303 |
N | 16 | T16M | aCg | aTg | 13 | 13 | B.1.177.20 | 0.019727 |
N | 16 | T16M | aCg | aTg | 13 | 13 | B.1.427 | 0.000656 |
N | 16 | T16M | aCg | aTg | 12 | 12 | AY.38 | 0.005991 |
N | 16 | T16M | aCg | aTg | 11 | 11 | B.1.177.43 | 0.016248 |
N | 16 | T16M | aCg | aTg | 11 | 11 | B.1.525 | 0.001245 |
N | 16 | T16M | aCg | aTg | 10 | 10 | AY.6 | 0.000411 |
N | 16 | T16M | aCg | aTg | 10 | 10 | B.1.1.214 | 0.000555 |
N | 16 | T16M | aCg | aTg | 9 | 9 | AY.118 | 0.000564 |
N | 16 | T16M | aCg | aTg | 9 | 9 | AY.39 | 0.000222 |
N | 16 | T16M | aCg | aTg | 8 | 8 | B.1.36 | 0.001167 |
N | 16 | T16M | aCg | aTg | 7 | 7 | AY.100 | 0.000322 |
N | 16 | T16M | aCg | aTg | 7 | 7 | AY.102 | 0.000186 |
N | 16 | T16M | aCg | aTg | 6 | 6 | AY.26 | 0.00017 |
N | 16 | T16M | aCg | aTg | 6 | 6 | AY.3.1 | 0.000512 |
N | 16 | T16M | aCg | aTg | 6 | 6 | B.1.177.7 | 0.000989 |
N | 16 | T16M | aCg | aTg | 6 | 6 | B.1.369 | 0.001711 |
N | 16 | T16M | aCg | aTg | 6 | 6 | B.1.526 | 0.000141 |
N | 16 | T16M | aCg | aTg | 6 | 6 | B.1.595 | 0.001566 |
N | 16 | T16M | aCg | aTg | 5 | 5 | AY.119 | 0.000177 |
N | 16 | T16M | aCg | aTg | 5 | 5 | AY.121 | 0.000677 |
N | 16 | T16M | aCg | aTg | 5 | 5 | AY.46 | 0.00052 |
N | 16 | T16M | aCg | aTg | 5 | 5 | AY.5 | 0.000103 |
N | 16 | T16M | aCg | aTg | 5 | 5 | B.1.258 | 0.000333 |
N | 16 | T16M | aCg | aTg | 5 | 5 | P.1.7 | 0.001596 |
N | 16 | T16M | aCg | aTg | 4 | 4 | AY.20 | 0.000155 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.1.28 | 0.001245 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.1.317 | 0.001647 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.177.44 | 0.002076 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.177.56 | 0.00267 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.400 | 0.001716 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.599 | 0.014599 |
N | 16 | T16M | aCg | aTg | 4 | 4 | B.1.600 | 0.023392 |
N | 16 | T16M | aCg | aTg | 3 | 3 | AY.29 | 0.000047 |
N | 16 | T16M | aCg | aTg | 3 | 3 | AY.54 | 0.000286 |
N | 16 | T16M | aCg | aTg | 3 | 3 | AY.98 | 0.000237 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.1.228 | 0.009146 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.1.429 | 0.013825 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.1.519 | 0.000119 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.160.20 | 0.026786 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.160.26 | 0.007264 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.177.60 | 0.000655 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.177.75 | 0.003122 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.221 | 0.000213 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.597 | 0.013889 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.621 | 0.000266 |
N | 16 | T16M | aCg | aTg | 3 | 3 | B.1.621.1 | 0.001517 |
N | 16 | T16M | aCg | aTg | 3 | 3 | P.2 | 0.00056 |
N | 16 | T16M | aCg | aTg | 2 | 2 | A | 0.000774 |
N | 16 | T16M | aCg | aTg | 2 | 2 | A.23.1 | 0.001408 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AU.2 | 0.004843 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.1 | 0.000791 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.34 | 0.000194 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.39.1 | 0.000079 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.62 | 0.000871 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.67 | 0.000929 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.74 | 0.000231 |
N | 16 | T16M | aCg | aTg | 2 | 2 | AY.99.2 | 0.000184 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.161 | 0.007067 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.189 | 0.003026 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.27 | 0.011299 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.294 | 0.002532 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.39 | 0.001019 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.412 | 0.015267 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.50 | 0.001358 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.1.63 | 0.000772 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.177.6 | 0.001953 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.243 | 0.000139 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.3 | 0.005236 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.444 | 0.031746 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.466.2 | 0.000782 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.517.1 | 0.010526 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.580 | 0.00813 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.1.619.1 | 0.001283 |
N | 16 | T16M | aCg | aTg | 2 | 2 | B.23 | 0.005848 |
N | 16 | T16M | aCg | aTg | 2 | 2 | C.31 | 0.035714 |
N | 16 | T16M | aCg | aTg | 2 | 2 | P.1.15 | 0.000465 |
N | 16 | T16M | aCg | aTg | 2 | 2 | Q.8 | 0.00033 |
N | 16 | T16M | aCg | aTg | 2 | 2 | R.1 | 0.00018 |
N | 16 | T16M | aCg | aTg | 1 | 1 | A.3 | 0.002096 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AB.1 | 0.008197 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AQ.2 | 0.111111 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.101 | 0.00049 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.120 | 0.000037 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.16.1 | 0.00047 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.23 | 0.00007 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.27 | 0.000065 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.33 | 0.000067 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.42 | 0.00004 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.45 | 0.000122 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.48 | 0.000465 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.66 | 0.00107 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.7 | 0.000196 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.85 | 0.000427 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.9.1 | 0.000084 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.9.2 | 0.000037 |
N | 16 | T16M | aCg | aTg | 1 | 1 | AY.93 | 0.000273 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.1 | 0.000327 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.117 | 0.009709 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.219 | 0.005 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.282 | 0.011628 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.298 | 0.000862 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.304 | 0.002809 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.33 | 0.000421 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.37 | 0.000193 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.435 | 0.034483 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.461 | 0.012048 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.464 | 0.001473 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.523 | 0.001563 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.1.70 | 0.000341 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.110 | 0.004525 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.120 | 0.007692 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.146 | 0.004237 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.11 | 0.001698 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.12 | 0.000152 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.16 | 0.000664 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.32 | 0.00135 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.35 | 0.000691 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.4 | 0.000211 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.45 | 0.000381 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.5 | 0.001242 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.57 | 0.000281 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.62 | 0.001192 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.76 | 0.002494 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.77 | 0.000726 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.81 | 0.000189 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.83 | 0.001481 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.87 | 0.000728 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.177.9 | 0.001332 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.199 | 0.004132 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.210 | 0.002132 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.214.2 | 0.0006 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.234 | 0.000132 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.240 | 0.000216 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.258.5 | 0.008772 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.265 | 0.001271 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.36.7 | 0.004 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.361 | 0.001289 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.416 | 0.001269 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.423 | 0.010204 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.438.1 | 0.000107 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.443 | 0.004673 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.503 | 0.002488 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.504 | 0.03125 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.561 | 0.000397 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.564 | 0.000426 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.575.1 | 0.002439 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.623 | 0.000536 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.627 | 0.00202 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.1.88.1 | 0.004808 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.40 | 0.000364 |
N | 16 | T16M | aCg | aTg | 1 | 1 | B.6.6 | 0.000889 |
N | 16 | T16M | aCg | aTg | 1 | 1 | C.37 | 0.000116 |
N | 16 | T16M | aCg | aTg | 1 | 1 | D.2 | 0.000075 |
N | 16 | T16M | aCg | aTg | 1 | 1 | P.1.12 | 0.000484 |
N | 16 | T16M | aCg | aTg | 1 | 1 | P.1.14 | 0.000048 |
N | 16 | T16M | aCg | aTg | 1 | 1 | P.1.17 | 0.000162 |
N | 16 | T16M | aCg | aTg | 1 | 1 | Q.1 | 0.000126 |
N | 16 | T16M | aCg | aTg | 1 | 1 | Q.3 | 0.000145 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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