CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = N : CodonNum = 157 & Codon = aCc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
N	157	I157T		nonsyn	aTc	aCc	387	387	1	28742-28744

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
N	157	I157T	aTc	aCc	387	387	All	0.000074
N	157	I157T	aTc	aCc	80	80	P.1	0.00126
N	157	I157T	aTc	aCc	60	60	AY.4	0.000093
N	157	I157T	aTc	aCc	57	57	B.1.1.7	0.000051
N	157	I157T	aTc	aCc	34	34	B.1.617.2	0.000128
N	157	I157T	aTc	aCc	17	17	AY.43	0.000075
N	157	I157T	aTc	aCc	16	16	AY.42	0.000644
N	157	I157T	aTc	aCc	15	15	AY.44	0.000091
N	157	I157T	aTc	aCc	10	10	AY.25	0.00006
N	157	I157T	aTc	aCc	9	9	AY.92	0.002585
N	157	I157T	aTc	aCc	6	6	AY.103	0.000037
N	157	I157T	aTc	aCc	6	6	B	0.000767
N	157	I157T	aTc	aCc	5	5	B.1.177	0.000066
N	157	I157T	aTc	aCc	4	4	AY.120	0.000149
N	157	I157T	aTc	aCc	4	4	AY.3	0.00004
N	157	I157T	aTc	aCc	4	4	AY.4.5	0.00043
N	157	I157T	aTc	aCc	4	4	B.1.1	0.000073
N	157	I157T	aTc	aCc	4	4	B.1.2	0.000035
N	157	I157T	aTc	aCc	3	3	AY.102	0.00008
N	157	I157T	aTc	aCc	2	2	AY.100	0.000092
N	157	I157T	aTc	aCc	2	2	AY.117	0.000169
N	157	I157T	aTc	aCc	2	2	AY.20	0.000078
N	157	I157T	aTc	aCc	2	2	AY.84	0.000875
N	157	I157T	aTc	aCc	2	2	AY.98.1	0.000097
N	157	I157T	aTc	aCc	2	2	B.1.221	0.000142
N	157	I157T	aTc	aCc	2	2	B.1.258	0.000133
N	157	I157T	aTc	aCc	2	2	B.1.582	0.000981
N	157	I157T	aTc	aCc	1	1	AY.109	0.00074
N	157	I157T	aTc	aCc	1	1	AY.13	0.000161
N	157	I157T	aTc	aCc	1	1	AY.39	0.000025
N	157	I157T	aTc	aCc	1	1	AY.39.2	0.001541
N	157	I157T	aTc	aCc	1	1	AY.46	0.000104
N	157	I157T	aTc	aCc	1	1	AY.54	0.000095
N	157	I157T	aTc	aCc	1	1	AY.71	0.000475
N	157	I157T	aTc	aCc	1	1	AY.75	0.000056
N	157	I157T	aTc	aCc	1	1	AY.93	0.000273
N	157	I157T	aTc	aCc	1	1	AY.99.1	0.001553
N	157	I157T	aTc	aCc	1	1	AY.99.2	0.000092
N	157	I157T	aTc	aCc	1	1	B.1.1.28	0.000311
N	157	I157T	aTc	aCc	1	1	B.1.1.33	0.000421
N	157	I157T	aTc	aCc	1	1	B.1.160	0.000031
N	157	I157T	aTc	aCc	1	1	B.1.177.21	0.000076
N	157	I157T	aTc	aCc	1	1	B.1.177.33	0.001645
N	157	I157T	aTc	aCc	1	1	B.1.177.57	0.000281
N	157	I157T	aTc	aCc	1	1	B.1.236	0.002053
N	157	I157T	aTc	aCc	1	1	B.1.243	0.00007
N	157	I157T	aTc	aCc	1	1	B.1.258.17	0.000104
N	157	I157T	aTc	aCc	1	1	B.1.351.2	0.000303
N	157	I157T	aTc	aCc	1	1	B.1.429	0.000024
N	157	I157T	aTc	aCc	1	1	B.1.503	0.002488
N	157	I157T	aTc	aCc	1	1	B.1.526	0.000024
N	157	I157T	aTc	aCc	1	1	B.1.568	0.001111
N	157	I157T	aTc	aCc	1	1	B.1.595	0.000261
N	157	I157T	aTc	aCc	1	1	B.1.621	0.000089
N	157	I157T	aTc	aCc	1	1	B.1.621.1	0.000506
N	157	I157T	aTc	aCc	1	1	C.36.3	0.000567
N	157	I157T	aTc	aCc	1	1	C.37	0.000116
N	157	I157T	aTc	aCc	1	1	P.1.12	0.000484
N	157	I157T	aTc	aCc	1	1	P.1.13	0.000898
N	157	I157T	aTc	aCc	1	1	P.1.8	0.004785

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.