CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 70 | V70F | nonsyn | Gtt | Ttt | 4425 | 4425 | 1 | 26730-26732 |
Details of the mutation V70F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 70 | V70F | Gtt | Ttt | 4425 | 4425 | All | 0.000846 |
M | 70 | V70F | Gtt | Ttt | 838 | 838 | B.1.1.207 | 0.990544 |
M | 70 | V70F | Gtt | Ttt | 591 | 591 | AY.4 | 0.00092 |
M | 70 | V70F | Gtt | Ttt | 403 | 403 | B.1.1.7 | 0.000361 |
M | 70 | V70F | Gtt | Ttt | 369 | 369 | B.1.1 | 0.006694 |
M | 70 | V70F | Gtt | Ttt | 265 | 265 | B.1.617.2 | 0.000998 |
M | 70 | V70F | Gtt | Ttt | 131 | 131 | B.1 | 0.0012 |
M | 70 | V70F | Gtt | Ttt | 89 | 89 | B.1.1.344 | 0.956989 |
M | 70 | V70F | Gtt | Ttt | 87 | 87 | R.1 | 0.007831 |
M | 70 | V70F | Gtt | Ttt | 84 | 84 | AY.25 | 0.000505 |
M | 70 | V70F | Gtt | Ttt | 81 | 81 | AY.3 | 0.000806 |
M | 70 | V70F | Gtt | Ttt | 79 | 79 | AY.43 | 0.00035 |
M | 70 | V70F | Gtt | Ttt | 69 | 69 | P.1 | 0.001087 |
M | 70 | V70F | Gtt | Ttt | 67 | 67 | AY.100 | 0.003082 |
M | 70 | V70F | Gtt | Ttt | 67 | 67 | AY.103 | 0.000416 |
M | 70 | V70F | Gtt | Ttt | 66 | 66 | B.1.2 | 0.000581 |
M | 70 | V70F | Gtt | Ttt | 59 | 59 | B.1.177 | 0.000777 |
M | 70 | V70F | Gtt | Ttt | 58 | 58 | AY.44 | 0.000353 |
M | 70 | V70F | Gtt | Ttt | 46 | 46 | B.1.1.63 | 0.017747 |
M | 70 | V70F | Gtt | Ttt | 44 | 44 | AY.42 | 0.00177 |
M | 70 | V70F | Gtt | Ttt | 44 | 44 | B.1.1.519 | 0.001747 |
M | 70 | V70F | Gtt | Ttt | 39 | 39 | B.1.617.1 | 0.00503 |
M | 70 | V70F | Gtt | Ttt | 37 | 37 | AY.27 | 0.002395 |
M | 70 | V70F | Gtt | Ttt | 27 | 27 | AY.4.2 | 0.000586 |
M | 70 | V70F | Gtt | Ttt | 26 | 26 | B.1.596 | 0.002266 |
M | 70 | V70F | Gtt | Ttt | 25 | 25 | AY.119 | 0.000883 |
M | 70 | V70F | Gtt | Ttt | 24 | 24 | B.1.160 | 0.000749 |
M | 70 | V70F | Gtt | Ttt | 23 | 23 | B.1.177.77 | 0.016703 |
M | 70 | V70F | Gtt | Ttt | 22 | 22 | AY.39 | 0.000544 |
M | 70 | V70F | Gtt | Ttt | 19 | 19 | AY.102 | 0.000504 |
M | 70 | V70F | Gtt | Ttt | 19 | 19 | AY.61 | 0.001991 |
M | 70 | V70F | Gtt | Ttt | 18 | 18 | AY.29 | 0.000284 |
M | 70 | V70F | Gtt | Ttt | 18 | 18 | AY.98.1 | 0.000872 |
M | 70 | V70F | Gtt | Ttt | 18 | 18 | B.1.258 | 0.001198 |
M | 70 | V70F | Gtt | Ttt | 14 | 14 | AY.20 | 0.000544 |
M | 70 | V70F | Gtt | Ttt | 14 | 14 | B.1.279 | 0.007191 |
M | 70 | V70F | Gtt | Ttt | 13 | 13 | AY.14 | 0.001144 |
M | 70 | V70F | Gtt | Ttt | 13 | 13 | B.1.1.189 | 0.019667 |
M | 70 | V70F | Gtt | Ttt | 11 | 11 | B.1.1.311 | 0.00394 |
M | 70 | V70F | Gtt | Ttt | 11 | 11 | P.1.14 | 0.000526 |
M | 70 | V70F | Gtt | Ttt | 10 | 10 | B.1.526 | 0.000235 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | AY.113 | 0.001282 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | AY.121 | 0.001218 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | AY.23 | 0.000628 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | B.1.258.17 | 0.000936 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | B.1.497 | 0.002833 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | P.1.15 | 0.002091 |
M | 70 | V70F | Gtt | Ttt | 9 | 9 | V.2 | 0.290323 |
M | 70 | V70F | Gtt | Ttt | 8 | 8 | AY.26 | 0.000226 |
M | 70 | V70F | Gtt | Ttt | 8 | 8 | AY.33 | 0.000534 |
M | 70 | V70F | Gtt | Ttt | 8 | 8 | AY.47 | 0.000249 |
M | 70 | V70F | Gtt | Ttt | 8 | 8 | B.1.1.348 | 0.006369 |
M | 70 | V70F | Gtt | Ttt | 8 | 8 | P.1.7 | 0.002554 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | AY.46.6 | 0.000505 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | AY.75 | 0.000392 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | AY.99.2 | 0.000645 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | B.1.1.507 | 0.06087 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | B.1.427 | 0.000353 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | B.1.525 | 0.000792 |
M | 70 | V70F | Gtt | Ttt | 7 | 7 | B.1.628 | 0.002467 |
M | 70 | V70F | Gtt | Ttt | 6 | 6 | AY.29.1 | 0.001323 |
M | 70 | V70F | Gtt | Ttt | 6 | 6 | AY.6 | 0.000247 |
M | 70 | V70F | Gtt | Ttt | 6 | 6 | B.1.1.214 | 0.000333 |
M | 70 | V70F | Gtt | Ttt | 6 | 6 | B.1.609 | 0.002876 |
M | 70 | V70F | Gtt | Ttt | 6 | 6 | B.1.621 | 0.000531 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | AY.111 | 0.000916 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | AY.53 | 0.001438 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | AY.93 | 0.001365 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | B | 0.000639 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | B.1.243 | 0.000348 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | B.1.252 | 0.033113 |
M | 70 | V70F | Gtt | Ttt | 5 | 5 | B.1.351.2 | 0.001513 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | A | 0.001548 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.114 | 0.000924 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.117 | 0.000338 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.3.1 | 0.000341 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.34 | 0.000388 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.4.4 | 0.001637 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.45 | 0.000487 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | AY.46 | 0.000416 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.25 | 0.002274 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.284 | 0.00043 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.301 | 0.004717 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.37 | 0.000771 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.462 | 0.034483 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.1.61 | 0.035088 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.139 | 0.002933 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.177.60 | 0.000874 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.214.2 | 0.002398 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.240 | 0.000862 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | B.1.637 | 0.000292 |
M | 70 | V70F | Gtt | Ttt | 4 | 4 | C.35 | 0.003096 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.105 | 0.001929 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.116 | 0.00086 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.120 | 0.000112 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.46.1 | 0.00308 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.5 | 0.000062 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.75.1 | 0.000541 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.9 | 0.000203 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | AY.9.2 | 0.00011 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.351 | 0.000089 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.36 | 0.000438 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.415.1 | 0.022727 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.429 | 0.000071 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.587 | 0.005693 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.1.627 | 0.006061 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | B.4 | 0.006623 |
M | 70 | V70F | Gtt | Ttt | 3 | 3 | P.1.13 | 0.002695 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.118 | 0.000125 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.16 | 0.000759 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.37 | 0.000632 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.4.5 | 0.000215 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.46.5 | 0.000397 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.5.4 | 0.000553 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.55 | 0.001835 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.59 | 0.001059 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.69 | 0.000373 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.7 | 0.000392 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.84 | 0.000875 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.92 | 0.000575 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | AY.99 | 0.002099 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.1 | 0.000653 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.216 | 0.001781 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.279 | 0.002242 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.326 | 0.003521 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.369 | 0.000892 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.398 | 0.006452 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.1.410 | 0.074074 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.160.8 | 0.002577 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.177.33 | 0.003289 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.177.81 | 0.000379 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.177.87 | 0.001456 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.210 | 0.004264 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.221 | 0.000142 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.234 | 0.000264 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.517 | 0.000854 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.564 | 0.000852 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | B.1.595 | 0.000522 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | C.36 | 0.001821 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | C.37 | 0.000232 |
M | 70 | V70F | Gtt | Ttt | 2 | 2 | P.1.16 | 0.000748 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | A.2.2 | 0.001689 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | A.2.4 | 0.003367 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AP.1 | 0.001502 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.107 | 0.000466 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.22 | 0.002092 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.34.1 | 0.00051 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.38 | 0.000499 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.39.1 | 0.00004 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.4.3 | 0.000842 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.5.3 | 0.000337 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.62 | 0.000436 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.64 | 0.000595 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.67 | 0.000464 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.7.1 | 0.000113 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.70 | 0.000209 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.77 | 0.001127 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.89 | 0.004902 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.9.1 | 0.000084 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.94 | 0.000443 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.95 | 0.000761 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AY.97 | 0.001701 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | AZ.3 | 0.00152 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.174 | 0.003378 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.205 | 0.003717 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.222 | 0.000204 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.261 | 0.008621 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.274 | 0.005051 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.277 | 0.000759 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.306 | 0.000438 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.307 | 0.002532 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.317 | 0.000412 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.33 | 0.000421 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.41 | 0.006329 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.44 | 0.00241 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.1.50 | 0.000679 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.104 | 0.00369 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.158 | 0.02381 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.19 | 0.001431 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.21 | 0.000076 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.23 | 0.003236 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.43 | 0.001477 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.54 | 0.000606 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.57 | 0.000281 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.177.65 | 0.000665 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.179 | 0.003759 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.232 | 0.000537 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.236 | 0.002053 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.311 | 0.000275 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.356 | 0.001727 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.36.35 | 0.002604 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.367 | 0.000792 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.378 | 0.006849 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.383 | 0.009009 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.393 | 0.028571 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.416 | 0.001269 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.418 | 0.015873 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.438.1 | 0.000107 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.444 | 0.015873 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.582 | 0.000491 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.589 | 0.007576 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.619 | 0.000871 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.625 | 0.002353 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.1.638 | 0.052632 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.27 | 0.015385 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.28 | 0.003279 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.6 | 0.00091 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | B.6.6 | 0.000889 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | C.36.3 | 0.000567 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | D.2 | 0.000075 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | N.1 | 0.016949 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | N.4 | 0.004255 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | N.5 | 0.001767 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | P.1.12 | 0.000484 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | P.2 | 0.000187 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | Q.3 | 0.000145 |
M | 70 | V70F | Gtt | Ttt | 1 | 1 | Q.4 | 0.000455 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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