CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = M : Mut = T208I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
M	208	T208I		nonsyn	aCa	aTa	2199	2199	1	27144-27146

Details of the mutation T208I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
M	208	T208I	aCa	aTa	2199	2199	All	0.000421
M	208	T208I	aCa	aTa	386	386	B.1.1.7	0.000346
M	208	T208I	aCa	aTa	190	190	B.1.517.1	1
M	208	T208I	aCa	aTa	164	164	AY.4	0.000255
M	208	T208I	aCa	aTa	129	129	AY.29	0.002035
M	208	T208I	aCa	aTa	105	105	AY.43	0.000465
M	208	T208I	aCa	aTa	93	93	B.1.617.2	0.00035
M	208	T208I	aCa	aTa	87	87	AY.103	0.00054
M	208	T208I	aCa	aTa	66	66	B.1.1.519	0.002621
M	208	T208I	aCa	aTa	64	64	B.1.2	0.000564
M	208	T208I	aCa	aTa	55	55	AY.3	0.000547
M	208	T208I	aCa	aTa	49	49	AY.5	0.001012
M	208	T208I	aCa	aTa	46	46	AY.44	0.00028
M	208	T208I	aCa	aTa	43	43	AY.25	0.000259
M	208	T208I	aCa	aTa	42	42	B.1.177	0.000553
M	208	T208I	aCa	aTa	40	40	AY.7.1	0.004508
M	208	T208I	aCa	aTa	36	36	B.1.351	0.00107
M	208	T208I	aCa	aTa	31	31	B.1	0.000284
M	208	T208I	aCa	aTa	28	28	B.1.526	0.000658
M	208	T208I	aCa	aTa	27	27	AY.26	0.000764
M	208	T208I	aCa	aTa	19	19	AY.4.2	0.000412
M	208	T208I	aCa	aTa	18	18	AY.47	0.00056
M	208	T208I	aCa	aTa	16	16	AY.102	0.000424
M	208	T208I	aCa	aTa	15	15	AY.42	0.000603
M	208	T208I	aCa	aTa	15	15	B.1.1	0.000272
M	208	T208I	aCa	aTa	14	14	B.1.221	0.000994
M	208	T208I	aCa	aTa	12	12	AY.100	0.000552
M	208	T208I	aCa	aTa	12	12	B.1.575	0.003641
M	208	T208I	aCa	aTa	12	12	P.1	0.000189
M	208	T208I	aCa	aTa	11	11	AY.98	0.000869
M	208	T208I	aCa	aTa	10	10	AY.117	0.000845
M	208	T208I	aCa	aTa	10	10	B.1.427	0.000505
M	208	T208I	aCa	aTa	9	9	AY.119	0.000318
M	208	T208I	aCa	aTa	9	9	AY.35	0.002097
M	208	T208I	aCa	aTa	9	9	B.1.621	0.000797
M	208	T208I	aCa	aTa	8	8	AY.39	0.000198
M	208	T208I	aCa	aTa	8	8	AY.7.2	0.004474
M	208	T208I	aCa	aTa	8	8	B.1.637	0.000585
M	208	T208I	aCa	aTa	7	7	AY.20	0.000272
M	208	T208I	aCa	aTa	6	6	AY.120	0.000223
M	208	T208I	aCa	aTa	6	6	AY.23	0.000418
M	208	T208I	aCa	aTa	6	6	AY.9.2	0.00022
M	208	T208I	aCa	aTa	6	6	Q.1	0.000758
M	208	T208I	aCa	aTa	6	6	R.1	0.00054
M	208	T208I	aCa	aTa	5	5	AY.111	0.000916
M	208	T208I	aCa	aTa	5	5	AY.46.6	0.000361
M	208	T208I	aCa	aTa	5	5	AY.9	0.000338
M	208	T208I	aCa	aTa	5	5	AY.98.1	0.000242
M	208	T208I	aCa	aTa	5	5	AY.99.2	0.000461
M	208	T208I	aCa	aTa	5	5	B.1.1.10	0.005574
M	208	T208I	aCa	aTa	5	5	B.1.1.316	0.004625
M	208	T208I	aCa	aTa	5	5	B.1.177.65	0.003327
M	208	T208I	aCa	aTa	5	5	B.1.429	0.000118
M	208	T208I	aCa	aTa	5	5	D.2	0.000375
M	208	T208I	aCa	aTa	5	5	P.1.14	0.000239
M	208	T208I	aCa	aTa	4	4	AY.121	0.000541
M	208	T208I	aCa	aTa	4	4	AY.58	0.00363
M	208	T208I	aCa	aTa	4	4	AY.74	0.000463
M	208	T208I	aCa	aTa	4	4	B.1.1.141	0.008048
M	208	T208I	aCa	aTa	4	4	B.1.258	0.000266
M	208	T208I	aCa	aTa	3	3	AY.118	0.000188
M	208	T208I	aCa	aTa	3	3	AY.29.1	0.000662
M	208	T208I	aCa	aTa	3	3	AY.33	0.0002
M	208	T208I	aCa	aTa	3	3	AY.36	0.000445
M	208	T208I	aCa	aTa	3	3	B.1.1.214	0.000166
M	208	T208I	aCa	aTa	3	3	B.1.1.347	0.054545
M	208	T208I	aCa	aTa	3	3	B.1.1.486	0.004732
M	208	T208I	aCa	aTa	3	3	B.1.177.7	0.000495
M	208	T208I	aCa	aTa	3	3	B.1.36	0.000438
M	208	T208I	aCa	aTa	3	3	B.1.525	0.000339
M	208	T208I	aCa	aTa	3	3	B.1.626	0.017143
M	208	T208I	aCa	aTa	3	3	P.2	0.00056
M	208	T208I	aCa	aTa	2	2	A.27	0.003311
M	208	T208I	aCa	aTa	2	2	AD.2	0.000438
M	208	T208I	aCa	aTa	2	2	AY.2	0.000712
M	208	T208I	aCa	aTa	2	2	AY.34	0.000194
M	208	T208I	aCa	aTa	2	2	AY.39.1	0.000079
M	208	T208I	aCa	aTa	2	2	AY.45	0.000243
M	208	T208I	aCa	aTa	2	2	AY.46.4	0.000329
M	208	T208I	aCa	aTa	2	2	AY.48	0.00093
M	208	T208I	aCa	aTa	2	2	AY.5.3	0.000675
M	208	T208I	aCa	aTa	2	2	AY.54	0.000191
M	208	T208I	aCa	aTa	2	2	AY.62	0.000871
M	208	T208I	aCa	aTa	2	2	AY.70	0.000417
M	208	T208I	aCa	aTa	2	2	AY.85	0.000854
M	208	T208I	aCa	aTa	2	2	B.1.1.222	0.000408
M	208	T208I	aCa	aTa	2	2	B.1.1.416	0.00181
M	208	T208I	aCa	aTa	2	2	B.1.160	0.000062
M	208	T208I	aCa	aTa	2	2	B.1.177.12	0.000303
M	208	T208I	aCa	aTa	2	2	B.1.210	0.004264
M	208	T208I	aCa	aTa	2	2	B.1.241	0.001623
M	208	T208I	aCa	aTa	2	2	B.1.305	0.004301
M	208	T208I	aCa	aTa	2	2	B.1.36.10	0.009569
M	208	T208I	aCa	aTa	2	2	B.1.413	0.008511
M	208	T208I	aCa	aTa	2	2	B.1.551	0.002581
M	208	T208I	aCa	aTa	2	2	B.1.564	0.000852
M	208	T208I	aCa	aTa	2	2	B.1.595	0.000522
M	208	T208I	aCa	aTa	2	2	B.1.595.4	0.014599
M	208	T208I	aCa	aTa	2	2	P.1.10	0.000539
M	208	T208I	aCa	aTa	2	2	P.1.15	0.000465
M	208	T208I	aCa	aTa	2	2	P.1.17	0.000324
M	208	T208I	aCa	aTa	2	2	P.1.4	0.001953
M	208	T208I	aCa	aTa	2	2	Q.3	0.00029
M	208	T208I	aCa	aTa	1	1	A	0.000387
M	208	T208I	aCa	aTa	1	1	A.2.2	0.001689
M	208	T208I	aCa	aTa	1	1	A.2.5.2	0.001572
M	208	T208I	aCa	aTa	1	1	A.21	0.00277
M	208	T208I	aCa	aTa	1	1	AU.3	0.00211
M	208	T208I	aCa	aTa	1	1	AY.109	0.00074
M	208	T208I	aCa	aTa	1	1	AY.113	0.000142
M	208	T208I	aCa	aTa	1	1	AY.114	0.000231
M	208	T208I	aCa	aTa	1	1	AY.116	0.000287
M	208	T208I	aCa	aTa	1	1	AY.12	0.000316
M	208	T208I	aCa	aTa	1	1	AY.120.1	0.000321
M	208	T208I	aCa	aTa	1	1	AY.14	0.000088
M	208	T208I	aCa	aTa	1	1	AY.16	0.00038
M	208	T208I	aCa	aTa	1	1	AY.39.2	0.001541
M	208	T208I	aCa	aTa	1	1	AY.41	0.000294
M	208	T208I	aCa	aTa	1	1	AY.46.2	0.000635
M	208	T208I	aCa	aTa	1	1	AY.56	0.001605
M	208	T208I	aCa	aTa	1	1	AY.59	0.00053
M	208	T208I	aCa	aTa	1	1	AY.6	0.000041
M	208	T208I	aCa	aTa	1	1	AY.61	0.000105
M	208	T208I	aCa	aTa	1	1	AY.64	0.000595
M	208	T208I	aCa	aTa	1	1	AY.73	0.000665
M	208	T208I	aCa	aTa	1	1	AY.75	0.000056
M	208	T208I	aCa	aTa	1	1	AY.75.1	0.00018
M	208	T208I	aCa	aTa	1	1	AY.79	0.001211
M	208	T208I	aCa	aTa	1	1	AY.89	0.004902
M	208	T208I	aCa	aTa	1	1	AY.9.1	0.000084
M	208	T208I	aCa	aTa	1	1	AY.92	0.000287
M	208	T208I	aCa	aTa	1	1	B.1.1.186	0.003436
M	208	T208I	aCa	aTa	1	1	B.1.1.226	0.005814
M	208	T208I	aCa	aTa	1	1	B.1.1.231	0.003096
M	208	T208I	aCa	aTa	1	1	B.1.1.240	0.004695
M	208	T208I	aCa	aTa	1	1	B.1.1.25	0.000569
M	208	T208I	aCa	aTa	1	1	B.1.1.270	0.010309
M	208	T208I	aCa	aTa	1	1	B.1.1.273	0.006757
M	208	T208I	aCa	aTa	1	1	B.1.1.277	0.000759
M	208	T208I	aCa	aTa	1	1	B.1.1.284	0.000107
M	208	T208I	aCa	aTa	1	1	B.1.1.311	0.000358
M	208	T208I	aCa	aTa	1	1	B.1.1.317	0.000412
M	208	T208I	aCa	aTa	1	1	B.1.1.318	0.000302
M	208	T208I	aCa	aTa	1	1	B.1.1.33	0.000421
M	208	T208I	aCa	aTa	1	1	B.1.1.332	0.03125
M	208	T208I	aCa	aTa	1	1	B.1.1.50	0.000679
M	208	T208I	aCa	aTa	1	1	B.1.1.97	0.029412
M	208	T208I	aCa	aTa	1	1	B.1.110.3	0.000718
M	208	T208I	aCa	aTa	1	1	B.1.139	0.000733
M	208	T208I	aCa	aTa	1	1	B.1.147	0.000756
M	208	T208I	aCa	aTa	1	1	B.1.157	0.002985
M	208	T208I	aCa	aTa	1	1	B.1.177.10	0.000878
M	208	T208I	aCa	aTa	1	1	B.1.177.17	0.000821
M	208	T208I	aCa	aTa	1	1	B.1.177.21	0.000076
M	208	T208I	aCa	aTa	1	1	B.1.177.30	0.002513
M	208	T208I	aCa	aTa	1	1	B.1.177.58	0.001332
M	208	T208I	aCa	aTa	1	1	B.1.177.63	0.002703
M	208	T208I	aCa	aTa	1	1	B.1.177.68	0.015152
M	208	T208I	aCa	aTa	1	1	B.1.177.75	0.001041
M	208	T208I	aCa	aTa	1	1	B.1.177.77	0.000726
M	208	T208I	aCa	aTa	1	1	B.1.177.86	0.000183
M	208	T208I	aCa	aTa	1	1	B.1.179	0.003759
M	208	T208I	aCa	aTa	1	1	B.1.214.2	0.0006
M	208	T208I	aCa	aTa	1	1	B.1.232	0.000537
M	208	T208I	aCa	aTa	1	1	B.1.243	0.00007
M	208	T208I	aCa	aTa	1	1	B.1.252	0.006623
M	208	T208I	aCa	aTa	1	1	B.1.258.7	0.001912
M	208	T208I	aCa	aTa	1	1	B.1.258.9	0.005
M	208	T208I	aCa	aTa	1	1	B.1.264	0.012346
M	208	T208I	aCa	aTa	1	1	B.1.279	0.000514
M	208	T208I	aCa	aTa	1	1	B.1.311	0.000275
M	208	T208I	aCa	aTa	1	1	B.1.320	0.001245
M	208	T208I	aCa	aTa	1	1	B.1.325	0.006897
M	208	T208I	aCa	aTa	1	1	B.1.333	0.010526
M	208	T208I	aCa	aTa	1	1	B.1.349	0.000715
M	208	T208I	aCa	aTa	1	1	B.1.350	0.002933
M	208	T208I	aCa	aTa	1	1	B.1.351.2	0.000303
M	208	T208I	aCa	aTa	1	1	B.1.36.18	0.00042
M	208	T208I	aCa	aTa	1	1	B.1.360	0.012658
M	208	T208I	aCa	aTa	1	1	B.1.362	0.001541
M	208	T208I	aCa	aTa	1	1	B.1.408	0.00369
M	208	T208I	aCa	aTa	1	1	B.1.436	0.001029
M	208	T208I	aCa	aTa	1	1	B.1.438.1	0.000107
M	208	T208I	aCa	aTa	1	1	B.1.497	0.000315
M	208	T208I	aCa	aTa	1	1	B.1.509	0.000866
M	208	T208I	aCa	aTa	1	1	B.1.517	0.000427
M	208	T208I	aCa	aTa	1	1	B.1.561	0.000397
M	208	T208I	aCa	aTa	1	1	B.1.568	0.001111
M	208	T208I	aCa	aTa	1	1	B.1.609	0.000479
M	208	T208I	aCa	aTa	1	1	B.1.617.1	0.000129
M	208	T208I	aCa	aTa	1	1	B.1.628	0.000352
M	208	T208I	aCa	aTa	1	1	B.1.81	0.021277
M	208	T208I	aCa	aTa	1	1	B.1.93	0.000934
M	208	T208I	aCa	aTa	1	1	B.3.1	0.001658
M	208	T208I	aCa	aTa	1	1	B.4.8	0.071429
M	208	T208I	aCa	aTa	1	1	C.37	0.000116

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.