CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
M | 175 | T175M | nonsyn | aCg | aTg | 2790 | 2790 | 1 | 27045-27047 |
Details of the mutation T175M within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
M | 175 | T175M | aCg | aTg | 2790 | 2790 | All | 0.000534 |
M | 175 | T175M | aCg | aTg | 1222 | 1222 | B.1.1 | 0.022168 |
M | 175 | T175M | aCg | aTg | 196 | 196 | B.1.1.7 | 0.000175 |
M | 175 | T175M | aCg | aTg | 152 | 152 | AY.4 | 0.000237 |
M | 175 | T175M | aCg | aTg | 119 | 119 | B.1.617.2 | 0.000448 |
M | 175 | T175M | aCg | aTg | 103 | 103 | B.1.1.257 | 1 |
M | 175 | T175M | aCg | aTg | 82 | 82 | B.1 | 0.000751 |
M | 175 | T175M | aCg | aTg | 70 | 70 | B.1.1.323 | 0.985915 |
M | 175 | T175M | aCg | aTg | 52 | 52 | B.1.1.142 | 0.912281 |
M | 175 | T175M | aCg | aTg | 52 | 52 | B.1.1.17 | 0.866667 |
M | 175 | T175M | aCg | aTg | 48 | 48 | AY.43 | 0.000213 |
M | 175 | T175M | aCg | aTg | 43 | 43 | B.1.177 | 0.000566 |
M | 175 | T175M | aCg | aTg | 38 | 38 | AY.29 | 0.000599 |
M | 175 | T175M | aCg | aTg | 33 | 33 | AY.14 | 0.002904 |
M | 175 | T175M | aCg | aTg | 33 | 33 | AY.25 | 0.000198 |
M | 175 | T175M | aCg | aTg | 27 | 27 | AY.27 | 0.001747 |
M | 175 | T175M | aCg | aTg | 25 | 25 | AY.44 | 0.000152 |
M | 175 | T175M | aCg | aTg | 20 | 20 | B.1.177.60 | 0.004369 |
M | 175 | T175M | aCg | aTg | 20 | 20 | B.1.2 | 0.000176 |
M | 175 | T175M | aCg | aTg | 17 | 17 | AY.26 | 0.000481 |
M | 175 | T175M | aCg | aTg | 17 | 17 | B | 0.002173 |
M | 175 | T175M | aCg | aTg | 16 | 16 | AY.99.2 | 0.001475 |
M | 175 | T175M | aCg | aTg | 15 | 15 | AY.103 | 0.000093 |
M | 175 | T175M | aCg | aTg | 15 | 15 | AY.3 | 0.000149 |
M | 175 | T175M | aCg | aTg | 14 | 14 | AY.102 | 0.000371 |
M | 175 | T175M | aCg | aTg | 13 | 13 | AY.118 | 0.000814 |
M | 175 | T175M | aCg | aTg | 10 | 10 | AY.33 | 0.000668 |
M | 175 | T175M | aCg | aTg | 10 | 10 | AY.6 | 0.000411 |
M | 175 | T175M | aCg | aTg | 9 | 9 | B.1.1.222 | 0.001836 |
M | 175 | T175M | aCg | aTg | 9 | 9 | B.1.1.319 | 0.157895 |
M | 175 | T175M | aCg | aTg | 8 | 8 | AY.39 | 0.000198 |
M | 175 | T175M | aCg | aTg | 8 | 8 | B.1.1.434 | 0.002788 |
M | 175 | T175M | aCg | aTg | 8 | 8 | B.1.1.519 | 0.000318 |
M | 175 | T175M | aCg | aTg | 8 | 8 | B.1.391 | 0.009019 |
M | 175 | T175M | aCg | aTg | 8 | 8 | B.1.429 | 0.000188 |
M | 175 | T175M | aCg | aTg | 8 | 8 | B.1.596 | 0.000697 |
M | 175 | T175M | aCg | aTg | 7 | 7 | AY.3.1 | 0.000597 |
M | 175 | T175M | aCg | aTg | 7 | 7 | AY.75 | 0.000392 |
M | 175 | T175M | aCg | aTg | 6 | 6 | AY.20 | 0.000233 |
M | 175 | T175M | aCg | aTg | 6 | 6 | AY.5 | 0.000124 |
M | 175 | T175M | aCg | aTg | 6 | 6 | B.1.1.214 | 0.000333 |
M | 175 | T175M | aCg | aTg | 6 | 6 | B.1.351 | 0.000178 |
M | 175 | T175M | aCg | aTg | 6 | 6 | B.1.526 | 0.000141 |
M | 175 | T175M | aCg | aTg | 6 | 6 | P.1 | 0.000095 |
M | 175 | T175M | aCg | aTg | 5 | 5 | AY.32 | 0.002662 |
M | 175 | T175M | aCg | aTg | 5 | 5 | AY.42 | 0.000201 |
M | 175 | T175M | aCg | aTg | 5 | 5 | AY.54 | 0.000477 |
M | 175 | T175M | aCg | aTg | 5 | 5 | AY.98 | 0.000395 |
M | 175 | T175M | aCg | aTg | 5 | 5 | B.1.221 | 0.000355 |
M | 175 | T175M | aCg | aTg | 4 | 4 | AY.106 | 0.00134 |
M | 175 | T175M | aCg | aTg | 4 | 4 | AY.9.2 | 0.000147 |
M | 175 | T175M | aCg | aTg | 4 | 4 | B.1.177.57 | 0.001124 |
M | 175 | T175M | aCg | aTg | 4 | 4 | B.1.427 | 0.000202 |
M | 175 | T175M | aCg | aTg | 4 | 4 | B.1.509 | 0.003463 |
M | 175 | T175M | aCg | aTg | 4 | 4 | R.1 | 0.00036 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.114 | 0.000693 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.116.1 | 0.000934 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.120 | 0.000112 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.46.4 | 0.000494 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.47 | 0.000093 |
M | 175 | T175M | aCg | aTg | 3 | 3 | AY.9 | 0.000203 |
M | 175 | T175M | aCg | aTg | 3 | 3 | B.1.160 | 0.000094 |
M | 175 | T175M | aCg | aTg | 3 | 3 | B.1.234 | 0.000396 |
M | 175 | T175M | aCg | aTg | 3 | 3 | B.1.36 | 0.000438 |
M | 175 | T175M | aCg | aTg | 3 | 3 | D.2 | 0.000225 |
M | 175 | T175M | aCg | aTg | 3 | 3 | P.1.14 | 0.000143 |
M | 175 | T175M | aCg | aTg | 3 | 3 | P.1.15 | 0.000697 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.100 | 0.000092 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.111 | 0.000366 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.117 | 0.000169 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.29.1 | 0.000441 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.4.2 | 0.000043 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.4.2.1 | 0.000298 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.45 | 0.000243 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.46 | 0.000208 |
M | 175 | T175M | aCg | aTg | 2 | 2 | AY.62 | 0.000871 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.1.192 | 0.004619 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.1.311 | 0.000716 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.1.355 | 0.030769 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.177.81 | 0.000379 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.258 | 0.000133 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.351.2 | 0.000605 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.36.10 | 0.009569 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.612 | 0.005305 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.620 | 0.001892 |
M | 175 | T175M | aCg | aTg | 2 | 2 | B.1.621 | 0.000177 |
M | 175 | T175M | aCg | aTg | 2 | 2 | C.35 | 0.001548 |
M | 175 | T175M | aCg | aTg | 2 | 2 | C.36.3 | 0.001134 |
M | 175 | T175M | aCg | aTg | 1 | 1 | A | 0.000387 |
M | 175 | T175M | aCg | aTg | 1 | 1 | A.2 | 0.000662 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AE.8 | 0.000489 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.101 | 0.00049 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.121 | 0.000135 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.13 | 0.000161 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.15 | 0.002222 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.22 | 0.002092 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.23 | 0.00007 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.24 | 0.000431 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.34 | 0.000097 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.36 | 0.000148 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.4.5 | 0.000107 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.5.2 | 0.002463 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.51 | 0.000909 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.60 | 0.000938 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.64 | 0.000595 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.65 | 0.000533 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.69 | 0.000187 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.7 | 0.000196 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.75.1 | 0.00018 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.84 | 0.000437 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.91 | 0.00073 |
M | 175 | T175M | aCg | aTg | 1 | 1 | AY.93 | 0.000273 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.10 | 0.001115 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.161 | 0.003534 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.174 | 0.003378 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.220 | 0.001859 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.256 | 0.013699 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.268 | 0.014925 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.28 | 0.000311 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.284 | 0.000107 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.33 | 0.000421 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.356 | 0.008547 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.369 | 0.000446 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.419 | 0.007407 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.420 | 0.001006 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.462 | 0.008621 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.464 | 0.001473 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.481 | 0.071429 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.525 | 0.005464 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.70 | 0.000341 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.71 | 0.006061 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.1.8 | 0.003584 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.16 | 0.000664 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.32 | 0.00135 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.4 | 0.000211 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.46 | 0.000918 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.52 | 0.001757 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.62 | 0.001192 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.65 | 0.000665 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.177.83 | 0.001481 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.201 | 0.005682 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.206 | 0.000816 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.243 | 0.00007 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.258.17 | 0.000104 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.265 | 0.001271 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.279 | 0.000514 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.338 | 0.008621 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.36.17 | 0.000494 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.361 | 0.001289 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.362 | 0.001541 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.369 | 0.000285 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.404 | 0.001302 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.433 | 0.003195 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.516 | 0.001957 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.517 | 0.000427 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.551 | 0.00129 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.588 | 0.00091 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.609 | 0.000479 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.617.1 | 0.000129 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.628 | 0.000352 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.1.91 | 0.002075 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.28 | 0.003279 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.3 | 0.000831 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.3.1 | 0.001658 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.39 | 0.002331 |
M | 175 | T175M | aCg | aTg | 1 | 1 | B.4 | 0.002208 |
M | 175 | T175M | aCg | aTg | 1 | 1 | P.1.13 | 0.000898 |
M | 175 | T175M | aCg | aTg | 1 | 1 | P.1.4 | 0.000977 |
M | 175 | T175M | aCg | aTg | 1 | 1 | P.1.6 | 0.001946 |
M | 175 | T175M | aCg | aTg | 1 | 1 | P.3 | 0.001595 |
M | 175 | T175M | aCg | aTg | 1 | 1 | Q.2 | 0.000613 |
M | 175 | T175M | aCg | aTg | 1 | 1 | Q.8 | 0.000165 |
M | 175 | T175M | aCg | aTg | 1 | 1 | W.1 | 0.008696 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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